Ocular surface disease

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Information
Disease name
Ocular surface disease
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT06355128 Active, not recruiting A Cross-sectional Study of Ocular Manifestations During the Covid-19 Pandemic in Hubei Province January 1, 2024 April 30, 2024
NCT06404541 Active, not recruiting Phase 4 A Comparative Study Between Preservative With Benzalkonium Chloride vs Preservative Free Eye Drops on the Ocular Surface January 10, 2024 May 2024
NCT05938985 Active, not recruiting Croatian Version of the Ocular Surface Disease Index Questionnaire (OSDI) June 12, 2023 November 2, 2023
NCT01254370 Completed Phase 2 Safety and Efficacy Study of Catioprost® (Unpreserved Latanoprost 0.005% Emulsion) Compared to Travatan Z® to Treat Glaucoma and Ocular Surface Disease November 2010 June 2011
NCT01552174 Completed Management of Eyelid Disorders by Ophthalmologists in Usual Medical Practice March 2012 April 2014
NCT00346450 Completed Phase 3 Autologous ex Vivo Conjunctival Epithelial Cell Expansion for Ocular Surface Transplantation October 2001 December 2003
NCT00554411 Completed Assessing Ocular Surface Changes After Changing Glaucoma Medications November 2007 August 2011
NCT01178242 Completed N/A Salivary Gland Transplantation in the Treatment of Dry Eye in Patients With Stevens-Johnson Syndrome. December 2008 December 2010
NCT03923244 Completed N/A Dry Eye Syndrome Description During Cataract Surgery, With Multimodal Analysis of the Ocular Surface April 1, 2019 March 6, 2020
NCT03945071 Completed N/A The Effect of Punctal Plugs on Ocular Surface After Povidone-Iodine Preparation of Intravitreal Injection June 1, 2019 October 18, 2020
NCT03968731 Completed N/A Meibomian Gland Dysfunction Management With ZEST Protocol June 10, 2019 May 31, 2020
NCT04133311 Completed Phase 3 A Phase III Multinational Multicenter Investigator-Masked Randomized Active-Controlled Trial Comparing the Efficacy and Safety of DE-130A With Xalatan® in Patients With Open-Angle Glaucoma or Ocular Hypertension April 10, 2019 October 26, 2022
NCT04351100 Completed Efficacy of Diacerein on Ocular Surface Disease in Degenerative Arthritis Patients October 1, 2019 July 31, 2020
NCT04452279 Completed N/A Ocular Surface Disease Changes After iStent or iStent Inject Implantation With Phacoemulsification May 1, 2018 August 15, 2019
NCT04493658 Completed Differential Diagnosis of Sjögren's Versus Non-Sjögren's Dry Eye January 11, 2021 October 3, 2022
NCT04535388 Completed N/A LK Scleral Lens for Patients With Intractable Ocular Surface Diseases May 1, 2012 April 22, 2014
NCT04536129 Completed N/A Effects of Topical Low Dose Preservative-free Hydrocortisone on Intraocular Pressure November 4, 2019 March 4, 2020
NCT04649177 Completed N/A Pilot Study to Investigate the Feasibility, Reliability and Efficacy of Utilizing OCT to Automate PROSE Fitting December 15, 2020 March 23, 2022
NCT04673604 Completed N/A From Preserved, to Preservative-free Cyclosporine 0.1% Enhanced Triple Glaucoma Therapy May 6, 2018 June 29, 2020
NCT04812951 Completed Early Phase 1 Cyclosporine 0.1% Eye Drops as Prophylactic Treatment In Cataract Surgery February 17, 2021 February 23, 2022
NCT04828057 Completed Preservative-free Fixed-dose Combination of Tafluprost 0.0015% / Timolol 0.5% in Patients With Open-angle Glaucoma or Ocular Hypertension: Clinical Effectiveness, Tolerability and Safety in a Real World Setting September 1, 2021 August 24, 2022
NCT04918823 Completed Phase 1/Phase 2 Novel Use of Cyclosporine Ophthalmic Emulsion 0.05% on Application of PROSE Devices for Management of Patients With Ocular Surface Disease July 15, 2021 April 14, 2023
NCT04949295 Completed Evaluation of Ocular Surface in Hemodialysis Patients by Ocular Surface Analyzer January 1, 2021 December 31, 2021
NCT04960696 Completed Effect on Ocular Surface Symptoms of Online Education April 14, 2021 June 20, 2021
NCT05319470 Completed Ocular Surface Disease and IOP Monitoring With Travoprost Without Conservatives March 15, 2022 May 15, 2023
NCT05528016 Completed N/A Short and Long-term Results of Skin Versus Skin Plus Orbicularis Resection Blepharoplasty May 1, 2021 August 1, 2022
NCT05832996 Completed Phase 4 Cool vs Room-temperature Artificial Tears March 1, 2022 July 6, 2022
NCT06013436 Completed AST Combined With 0.05% Cyclosporin Eye Drop Improve Corneal Nerve Density in Patients With SS Dry Eye June 1, 2022 June 1, 2023
NCT02656394 Completed Phase 2 Amelioration of Adverse Ocular Side Effects of Glaucoma Medications in Glaucoma Patients Using Topical GL101 January 22, 2016 December 30, 2018
NCT02802137 Completed Phase 4 24-hour Efficacy and Ocular Surface With Talfuprost and Triple Combined Therapy March 2015 January 2016
NCT02999035 Completed Validation of a Newly Developed Liquid Jet Aesthesiometer January 2017 June 2017
NCT03302273 Completed N/A Corneal Epithelial Stem Cells and Dry Eye Disease February 1, 2019 April 1, 2022
NCT03364322 Completed Influencing Factors on Dry Eye Syndrome and Ocular Surface Disease June 1, 2016 June 30, 2017
NCT03659955 Completed N/A Autologous Blood Treatment for Ocular Surface Disease November 7, 2017 March 14, 2019
NCT03686059 Completed Phase 4 Outcome of Omega 3 FA and Punctal Plugs on Ocular Surface Disease July 2, 2018 November 20, 2019
NCT03769454 Completed Phase 1 A Phase I Study of PP-001 Eye Drops in Healthy Adult Volunteers November 20, 2018 March 15, 2022
NCT06370585 Not yet recruiting Phase 1 Clinical Study to Evaluate the Safety and Tolerability of PRO-229 Ophthalmic Solution Compared to Lagricel® Ofteno PF May 30, 2024 September 30, 2024
NCT06427629 Not yet recruiting N/A Investigator-initiated Clinical Trial to Observe Conjunctival Goblet Cell Using an Anterior Segment Imaging Device June 2024 June 2026
NCT06375343 Not yet recruiting Phase 1 Study to Evaluating PRO-240 Ophthalmic Solution Compared to Optive® October 30, 2024 June 2025
NCT04010422 Recruiting Ocular Function in Autism Spectrum Disorder May 15, 2019 December 31, 2023
NCT05195801 Recruiting Optic Nerve Diameter and Intraocular Pressure Changes in Patients Undergoing Vitrectomy Under General Anesthesia January 1, 2022 September 1, 2024
NCT04354545 Recruiting Treatment of Ocular Discomfort in Glaucoma Patients Using Multiple Topical Medications April 1, 2021 June 1, 2024
NCT06298890 Recruiting The Pattern of Dry Eye Disease After Cataract Surgery March 2024 September 2027
NCT06256770 Recruiting Evaluation of the Safety and Efficacy of Rigid Breathable Scleral Contact Lenses for the Correction of Ametropia November 1, 2022 December 1, 2024
NCT00348114 Suspended Phase 2 Transplantation of Cultivated Limbal Epithelium on Amniotic Membrane for Limbal Stem Cell Deficiency May 2002 May 2006
NCT03591874 Terminated Phase 3 Study of Brimonidine Tartrate Nanoemulsion Eye Drops in Patients With Ocular Graft-vs-Host Disease December 23, 2018 April 30, 2020
NCT01942421 Unknown status Phase 2/Phase 3 Ocular Surface Reconstruction With Cultivated Autologus Mucosal Epithelial Transplantation January 2008 December 2013
NCT04530864 Unknown status Phase 4 Pre-Surgical Ocular Surface Treatment With Intracanalicular Dexamethasone Insert And Effect On Intraocular Lens Measurement Accuracy January 2021 July 2021
NCT02894489 Unknown status N/A Changes of Visual Function, Ocular Surface Structures and Physiology After Long-Termed Contact Lens Wear August 2016 August 2019
NCT05247099 Unknown status Pediatric Eye Care Investigated Team February 2022 July 2022
NCT04608084 Unknown status Phase 4 Platelet Rich Plasma Eye Drops for Treatment of Ocular Surface Disease January 2021 January 2023
NCT04067973 Unknown status Impact of Prematurity on the Optic Nerve September 2, 2019 September 2, 2020
NCT01284439 Unknown status N/A Hydroxypropylmethylcellulose 0.3% and Sodium Hyaluronate 0.18% for Ocular Surface Disease in Glaucoma January 2011 February 2012
NCT05145959 Unknown status N/A Meibomian Gland Probing in the Sub-Acute Phase of Patients With Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis December 1, 2021 March 1, 2024
NCT01630551 Withdrawn N/A Omega 3 Supplementation and Ocular Surface Disease in Glaucoma April 2012 February 2017
NCT04735510 Withdrawn Phase 3 Novel Use of Restasis and PROSE Devices May 2021 September 2021