Annotation Detail
Information
- Associated Genes
- THBS1
- Associated Variants
-
THBS1 MUTATION
THBS1 MUTATION - Associated Disease
- Tumor Angiogenesis
- Source Database
- DisGeNET
- Description
- They can modulate pro-angiogenic signals induced by vascular endothelial growth factor (VEGF) and anti-angiogenic signals induced by thrombospondin-1 (TSP-1), and therefore promote or inhibit tumor angiogenesis.
- Pubmed
- 26144623
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 3
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00325730246496364
Drugs