chr3:47057918:> Detail (hg19)

Information

Genome

Assembly Position
hg19 chr3:47,057,918-47,205,603
hg38 chr3:47,016,428-47,164,113 

HGVS

Type Transcript Protein
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

[No Data.]

Prediction

[No Data.]

ClinVar

Clinical Significance
Review star [No Data.]
Show details
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score Disease name Description Source Pubmed Links
<0.001 squamous cell carcinoma NA BeFree Detail
<0.001 carotid stenosis NA BeFree Detail
<0.001 cerebral infarction NA BeFree Detail
<0.001 Malignant tumor of cervix NA BeFree Detail
<0.001 Congenital chromosomal disease NA BeFree Detail
<0.001 colitis NA BeFree Detail
<0.001 ulcerative colitis NA BeFree Detail
0.001 colorectal carcinoma NA BeFree Detail
<0.001 Colorectal Neoplasms NA BeFree Detail
<0.001 Coronary Arteriosclerosis NA BeFree Detail
<0.001 Coronary heart disease NA BeFree Detail
0.120 adenoid cystic carcinoma NA CTD_human Detail
0.120 Phyllodes Tumor NA CTD_human Detail
<0.001 Fatty Liver NA BeFree Detail
<0.001 gastritis Myeloid HIF-1 is protective in Helicobacter pylori-mediated gastritis. BeFree 25710915 Detail
0.002 glioblastoma NA BeFree Detail
0.002 Glioma NA BeFree Detail
<0.001 Heart failure NA BeFree Detail
<0.001 congestive heart failure NA BeFree Detail
<0.001 hemangioma NA BeFree Detail
0.002 Von Hippel-Lindau syndrome We performed immunohistochemical studies on 23 hemangioblastomas, 13 meningiomas... BeFree 25310734 Detail
<0.001 HIV Infections NA BeFree Detail
<0.001 hyperglycemia NA BeFree Detail
<0.001 Hypertensive disease Dysregulation of HIF-1- and HIF-2-mediated transcription leads to imbalance of p... BeFree 25772710 Detail
<0.001 pulmonary hypertension NA BeFree Detail
<0.001 hypoglycemia NA BeFree Detail
<0.001 Inflammatory Bowel Diseases NA BeFree Detail
0.004 ischemia NA BeFree Detail
<0.001 Kidney Diseases NA BeFree Detail
<0.001 Kidney Neoplasm NA BeFree Detail
0.121 leukemia Histone methyltransferases, including MLL1, DOT1L, EZH2, and SETD2 are recurrent... BeFree,CTD_human 25592767 Detail
<0.001 Acute lymphocytic leukemia Mutations in epigenetic regulators including SETD2 are gained during relapse in ... BeFree 24662245 Detail
<0.001 Leukemia, Myelocytic, Acute ESKM was more potent in vivo against JMN mesothelioma, and effective against SET... BeFree 24850840 Detail
<0.001 Leukemia, Myelomonocytic, Chronic NA BeFree Detail
0.003 Liver neoplasms NA BeFree Detail
<0.001 lymphoma NA BeFree Detail
0.002 Malignant neoplasm of stomach NA BeFree Detail
0.002 melanoma NA BeFree Detail
<0.001 Melanoma, Experimental NA BeFree Detail
<0.001 multiple myeloma NA BeFree Detail
<0.001 myocardial infarction NA BeFree Detail
0.010 Neoplasm Metastasis Intratumoral hypoxia followed by stabilization/activation of hypoxia-inducible f... BeFree 25506893 Detail
<0.001 neuroblastoma NA BeFree Detail
0.002 ovarian carcinoma Hypoxia-inducible factor-1 (HIF-1) is one of the most promising pharmacological ... BeFree 25756515 Detail
<0.001 Pancreatic Neoplasm The aim of study was to discuss the correlation and regulatory mechanism of HIF-... BeFree 25119596 Detail
<0.001 peritonitis NA BeFree Detail
<0.001 pheochromocytoma NA BeFree Detail
<0.001 polycythemia NA BeFree Detail
<0.001 Precancerous Conditions NA BeFree Detail
<0.001 progeria NA BeFree Detail
<0.001 pulmonary fibrosis NA BeFree Detail
<0.001 retinal degeneration NA BeFree Detail
0.003 schizophrenia NA BeFree,GAD Detail
<0.001 systemic scleroderma NA BeFree Detail
<0.001 Skin Diseases, Infectious NA BeFree Detail
<0.001 Stomach Neoplasms NA BeFree Detail
0.001 Cerebrovascular accident Collectively, these results demonstrate that NCX1 expression is regulated by the... BeFree 25972164 Detail
<0.001 Thrombocythemia, Essential NA BeFree Detail
<0.001 thymoma Genes in histone modification [BAP1 (n = 6; 13%), SETD2 (n = 5; 11%), ASXL1 (n =... BeFree 25482724 Detail
<0.001 ureteral obstruction NA BeFree Detail
<0.001 Vascular Diseases NA BeFree Detail
<0.001 Ichthyosis, X-Linked NA BeFree Detail
<0.001 acute leukemia NA BeFree Detail
<0.001 Adenocarcinoma of rectum NA BeFree Detail
<0.001 Myocardial Ischemia NA BeFree Detail
<0.001 Adenocarcinoma of lung (disorder) NA BeFree Detail
<0.001 esophageal carcinoma NA BeFree Detail
<0.001 Secondary malignant neoplasm of bone NA BeFree Detail
0.120 Sotos' syndrome NA ORPHANET Detail
0.009 Tumor Progression As one of the major mediators of hypoxic response, hypoxia inducible factor-1 (H... BeFree 25101278 Detail
0.009 Tumor Progression HIF-1-mediated suppression of acyl-CoA dehydrogenases and fatty acid oxidation i... BeFree 25242319 Detail
0.009 Tumor Progression As NSD1 and SETD2 are known tumor suppressors and loss of H4K20 trimethylation i... BeFree 25611383 Detail
<0.001 thymic carcinoma Genes in histone modification [BAP1 (n = 6; 13%), SETD2 (n = 5; 11%), ASXL1 (n =... BeFree 25482724 Detail
<0.001 Pneumonia, Interstitial NA BeFree Detail
<0.001 Adenocarcinoma, Clear Cell NA BeFree Detail
<0.001 hemangioblastoma Expression of HIF-1 regulated proteins vascular endothelial growth factor, carbo... BeFree 25310734 Detail
<0.001 uveal melanoma NA BeFree Detail
0.003 pancreatic carcinoma Expression of HIF-1 in pancreatic cancer cells increased under the condition of ... BeFree 25119596 Detail
0.003 pancreatic carcinoma This study has investigated the effect of lentiviral vector-mediated RNA interfe... BeFree 25853522 Detail
<0.001 hemangioma of liver NA BeFree Detail
<0.001 Acute mountain sickness NA BeFree Detail
<0.001 Papillary thyroid carcinoma NA BeFree Detail
<0.001 Iron deficiency NA BeFree Detail
0.001 Malignant neoplasm of lung Endometral carcinoma is the most common malignant tumor of the female genital tr... BeFree 25556481 Detail
0.001 Malignant neoplasm of lung In addition, PA-12 blocked the nuclear translocalization of PKM2 in lung cancer ... BeFree 25813626 Detail
<0.001 Carcinoma breast stage IV NA BeFree Detail
<0.001 Metastatic melanoma NA BeFree Detail
<0.001 Liver and Intrahepatic Biliary Tract Carcinoma SIRT1 expression was associated with HIF1 protein accumulation in both the NBNC ... BeFree 25736100 Detail
0.004 Conventional (Clear Cell) Renal Cell Carcinoma In agreement, SETD2-mutant clear cell renal cell carcinoma (ccRCC) cells display... BeFree 24843002 Detail
0.004 Conventional (Clear Cell) Renal Cell Carcinoma Loss of MLH1 confers resistance to PI3Kβ inhibitors in renal clear cell carcinom... BeFree 25528216 Detail
0.004 Conventional (Clear Cell) Renal Cell Carcinoma miR-106b-5p targets tumor suppressor gene SETD2 to inactive its function in clea... BeFree 25714014 Detail
0.004 Conventional (Clear Cell) Renal Cell Carcinoma TGX221 is a novel inhibitor with high selectivity for ccRCC with VHL and SETD2 m... BeFree 25853938 Detail
0.004 Conventional (Clear Cell) Renal Cell Carcinoma PBRM1 was found to be mutated in about 40% of ccRCC tumors, whereas BAP1 and SET... BeFree 25873528 Detail
0.004 Conventional (Clear Cell) Renal Cell Carcinoma High selectivity of PI3Kβ inhibitors in SETD2-mutated renal clear cell carcinoma... BeFree 26537074 Detail
0.004 Solid tumour Hypoxia-inducible factor-1 (HIF-1) is a key heterodimeric transcription factor f... BeFree 24916276 Detail
<0.001 Adenocarcinoma of pancreas NA BeFree Detail
<0.001 cervix carcinoma NA BeFree Detail
<0.001 anaplastic astrocytoma NA BeFree Detail
<0.001 Adenocarcinoma of colon The BH3-mimetic obatoclax reduces HIF-1α levels and HIF-1 transcriptional activi... BeFree 25979228 Detail
<0.001 Malignant neoplasm of liver SIRT1 expression was associated with HIF1 protein accumulation in both the NBNC ... BeFree 25736100 Detail
0.004 Malignant neoplasm of pancreas Expression of HIF-1 in pancreatic cancer cells increased under the condition of ... BeFree 25119596 Detail
0.004 Malignant neoplasm of pancreas This study has investigated the effect of lentiviral vector-mediated RNA interfe... BeFree 25853522 Detail
<0.001 Trichoepithelioma We used immunohistochemical staining of formalin-fixed paraffin-embedded BCC (n ... BeFree 25181405 Detail
<0.001 Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site Myeloid HIF-1 is protective in Helicobacter pylori-mediated gastritis. BeFree 25710915 Detail
0.004 Malignant neoplasm of prostate NA BeFree Detail
<0.001 endometrial carcinoma 75 patients with endometrial carcinoma and 75 patients whose underwent hysterect... BeFree 25556481 Detail
<0.001 Secondary malignant neoplasm of liver NA BeFree Detail
<0.001 Thyroid carcinoma NA BeFree Detail
<0.001 Malignant glioma NA BeFree Detail
0.009 Carcinogenesis In our study, we examined a new therapeutic alternative in the treatment of mult... BeFree 24627437 Detail
0.009 Carcinogenesis As one of the major mediators of hypoxic response, hypoxia inducible factor-1 (H... BeFree 25101278 Detail
0.009 Carcinogenesis To examine whether HIF-1 is involved in the tumorigenesis of RMG-1 cells, we est... BeFree 25756515 Detail
0.009 Carcinogenesis Repression of ERβ contributes to tumorigenesis because it enables HIF-1/VEGF sig... BeFree 25818291 Detail
<0.001 Leukemogenesis NA BeFree Detail
0.004 prostate carcinoma NA BeFree Detail
<0.001 Chronic myeloproliferative disorder We screened 79 acute myeloid leukemia (AML) cell lines and found five positive f... BeFree 16408098 Detail
<0.001 Epithelial ovarian cancer NA BeFree Detail
<0.001 Progressive Neoplastic Disease NA BeFree Detail
0.005 breast carcinoma Human breast cancer database analysis revealed that increased expression (greate... BeFree 25587023 Detail
0.002 Carcinoma of lung Endometral carcinoma is the most common malignant tumor of the female genital tr... BeFree 25556481 Detail
0.002 Carcinoma of lung In addition, PA-12 blocked the nuclear translocalization of PKM2 in lung cancer ... BeFree 25813626 Detail
<0.001 Secondary malignant neoplasm of lymph node FOXP1 expression was significantly correlated with the expression of HIF1 and VE... BeFree 25778315 Detail
0.002 colon carcinoma Colon cancer cell response to the BH3-mimetic was unmodified by HIF-1 activation... BeFree 25979228 Detail
0.002 stomach carcinoma NA BeFree Detail
<0.001 Central neuroblastoma NA BeFree Detail
<0.001 Malignant neoplasm of kidney NA BeFree Detail
<0.001 Cardiac defects NA BeFree Detail
<0.001 malignant pleural mesothelioma NA BeFree Detail
<0.001 Invasive breast carcinoma NA BeFree Detail
<0.001 Stromal Neoplasm NA BeFree Detail
<0.001 Cerebral Ischemia NA BeFree Detail
<0.001 ovarian neoplasm NA BeFree Detail
0.120 Microsatellite Instability NA CTD_human Detail
<0.001 Spondylarthropathies NA BeFree Detail
0.002 Malignant neoplasm of ovary Hypoxia-inducible factor-1 (HIF-1) is one of the most promising pharmacological ... BeFree 25756515 Detail
<0.001 Squamous cell carcinoma of the head and neck NA BeFree Detail
<0.001 sarcoma NA BeFree Detail
<0.001 Chronic myeloproliferative disorder NA BeFree Detail
<0.001 Staphylococcus aureus infection NA BeFree Detail
<0.001 Thymoma, type C Genes in histone modification [BAP1 (n = 6; 13%), SETD2 (n = 5; 11%), ASXL1 (n =... BeFree 25482724 Detail
<0.001 Hereditary Nonpolyposis Colorectal Cancer NA BeFree Detail
<0.001 Non-Hereditary Clear Cell Renal Cell Carcinoma NA BeFree Detail
<0.001 pancreatic ductal adenocarcinoma NA BeFree Detail
<0.001 Papillary renal cell carcinoma, sporadic NA BeFree Detail
0.001 renal carcinoma NA BeFree Detail
0.120 Mammary Neoplasms NA BeFree,CTD_human Detail
<0.001 Angiogenic Switch NA BeFree Detail
0.007 Tumor Angiogenesis During tumor progression, hypoxia-inducible factor 1 (HIF-1) plays a critical ro... BeFree 26297910 Detail
<0.001 Tumor Expansion NA BeFree Detail
<0.001 Tumor Promotion NA BeFree Detail
0.001 colorectal cancer NA BeFree Detail
<0.001 cancer angiogenesis NA BeFree Detail
0.001 Glioblastoma multiforme NA BeFree Detail
<0.001 tumor vasculature NA BeFree Detail
<0.001 ABLEPHARON-MACROSTOMIA SYNDROME NA BeFree Detail
<0.001 uterine corpus cancer In this study, we aimed to investigate the association between HIF-1 1772 C/T po... BeFree 25556481 Detail
0.006 liver carcinoma We also summarized the latest findings concerning the role of HIF-1 in the devel... BeFree 25101278 Detail
0.006 liver carcinoma Hypoxia inducible factor-1 (HIF-1) is one of the key mediators of the hypoxia si... BeFree 25531114 Detail
0.006 liver carcinoma Thus, NF-κB both positively and negatively fine-tuned HIF-1 in hypoxic hepatocar... BeFree 25823824 Detail
<0.001 aggressive cancer NA BeFree Detail
<0.001 Progressive cGVHD NA BeFree Detail
<0.001 Triple Negative Breast Neoplasms NA BeFree Detail
<0.001 Experimental Organism Basal Cell Carcinoma We used immunohistochemical staining of formalin-fixed paraffin-embedded BCC (n ... BeFree 25181405 Detail
<0.001 Tumors in animals NA BeFree Detail
<0.001 Abscess NA BeFree Detail
<0.001 adenocarcinoma NA BeFree Detail
<0.001 adenoma NA BeFree Detail
<0.001 anemia NA BeFree Detail
<0.001 arteriosclerosis NA BeFree Detail
<0.001 rheumatoid arthritis NA BeFree Detail
<0.001 Astrocytoma NA BeFree Detail
<0.001 atherosclerosis NA BeFree Detail
<0.001 Bacterial Infections NA BeFree Detail
0.006 Malignant neoplasm of breast Human breast cancer database analysis revealed that increased expression (greate... BeFree 25587023 Detail
0.002 Malignant tumor of colon Colon cancer cell response to the BH3-mimetic was unmodified by HIF-1 activation... BeFree 25979228 Detail
<0.001 Malignant neoplasm of endometrium In this study, we aimed to investigate the association between HIF-1 1772 C/T po... BeFree 25556481 Detail
<0.001 Rectal Carcinoma NA BeFree Detail
<0.001 Non-small cell lung carcinoma NA BeFree Detail
<0.001 Carcinoma, Papillary NA BeFree Detail
0.124 renal cell carcinoma MOTIF analysis of aberrantly hypermethylated regions revealed enrichment for bin... BeFree,CTD_human 24916699 Detail
0.124 renal cell carcinoma PI3Kβ inhibitor TGX221 selectively inhibits renal cell carcinoma cells with both... BeFree,CTD_human 25853938 Detail
Annotation

Annotations

DescrptionSourceLinks
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Myeloid HIF-1 is protective in Helicobacter pylori-mediated gastritis. DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
We performed immunohistochemical studies on 23 hemangioblastomas, 13 meningiomas and 4 hemangioperic... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Dysregulation of HIF-1- and HIF-2-mediated transcription leads to imbalance of pro-oxidant and anti-... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Histone methyltransferases, including MLL1, DOT1L, EZH2, and SETD2 are recurrently deregulated in hu... DisGeNET Detail
Mutations in epigenetic regulators including SETD2 are gained during relapse in paediatric acute lym... DisGeNET Detail
ESKM was more potent in vivo against JMN mesothelioma, and effective against SET2 AML and fresh ALL ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Intratumoral hypoxia followed by stabilization/activation of hypoxia-inducible factor 1 (HIF-1) and ... DisGeNET Detail
NA DisGeNET Detail
Hypoxia-inducible factor-1 (HIF-1) is one of the most promising pharmacological targets for all type... DisGeNET Detail
The aim of study was to discuss the correlation and regulatory mechanism of HIF-1 and miR-191 expres... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Collectively, these results demonstrate that NCX1 expression is regulated by the Sp3/REST/HDAC1/HDAC... DisGeNET Detail
NA DisGeNET Detail
Genes in histone modification [BAP1 (n = 6; 13%), SETD2 (n = 5; 11%), ASXL1 (n = 2; 4%)], chromatin ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
As one of the major mediators of hypoxic response, hypoxia inducible factor-1 (HIF-1) has been shown... DisGeNET Detail
HIF-1-mediated suppression of acyl-CoA dehydrogenases and fatty acid oxidation is critical for cance... DisGeNET Detail
As NSD1 and SETD2 are known tumor suppressors and loss of H4K20 trimethylation is an early event in ... DisGeNET Detail
Genes in histone modification [BAP1 (n = 6; 13%), SETD2 (n = 5; 11%), ASXL1 (n = 2; 4%)], chromatin ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Expression of HIF-1 regulated proteins vascular endothelial growth factor, carbonic anhydrase IX and... DisGeNET Detail
NA DisGeNET Detail
Expression of HIF-1 in pancreatic cancer cells increased under the condition of chronic hypoxia, whi... DisGeNET Detail
This study has investigated the effect of lentiviral vector-mediated RNA interference (RNAi) targeti... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Endometral carcinoma is the most common malignant tumor of the female genital tract and the fourth m... DisGeNET Detail
In addition, PA-12 blocked the nuclear translocalization of PKM2 in lung cancer cells, resulting in ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
SIRT1 expression was associated with HIF1 protein accumulation in both the NBNC liver and liver canc... DisGeNET Detail
In agreement, SETD2-mutant clear cell renal cell carcinoma (ccRCC) cells displayed impaired DNA dama... DisGeNET Detail
Loss of MLH1 confers resistance to PI3Kβ inhibitors in renal clear cell carcinoma with SETD2 mutatio... DisGeNET Detail
miR-106b-5p targets tumor suppressor gene SETD2 to inactive its function in clear cell renal cell ca... DisGeNET Detail
TGX221 is a novel inhibitor with high selectivity for ccRCC with VHL and SETD2 mutations. DisGeNET Detail
PBRM1 was found to be mutated in about 40% of ccRCC tumors, whereas BAP1 and SETD2 were each mutated... DisGeNET Detail
High selectivity of PI3Kβ inhibitors in SETD2-mutated renal clear cell carcinoma. DisGeNET Detail
Hypoxia-inducible factor-1 (HIF-1) is a key heterodimeric transcription factor for the cellular adap... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The BH3-mimetic obatoclax reduces HIF-1α levels and HIF-1 transcriptional activity and sensitizes hy... DisGeNET Detail
SIRT1 expression was associated with HIF1 protein accumulation in both the NBNC liver and liver canc... DisGeNET Detail
Expression of HIF-1 in pancreatic cancer cells increased under the condition of chronic hypoxia, whi... DisGeNET Detail
This study has investigated the effect of lentiviral vector-mediated RNA interference (RNAi) targeti... DisGeNET Detail
We used immunohistochemical staining of formalin-fixed paraffin-embedded BCC (n = 45) and TE (n = 35... DisGeNET Detail
Myeloid HIF-1 is protective in Helicobacter pylori-mediated gastritis. DisGeNET Detail
NA DisGeNET Detail
75 patients with endometrial carcinoma and 75 patients whose underwent hysterectomy for non tumoral ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
In our study, we examined a new therapeutic alternative in the treatment of multiresistant lung aden... DisGeNET Detail
As one of the major mediators of hypoxic response, hypoxia inducible factor-1 (HIF-1) has been shown... DisGeNET Detail
To examine whether HIF-1 is involved in the tumorigenesis of RMG-1 cells, we established HIF-1α-sile... DisGeNET Detail
Repression of ERβ contributes to tumorigenesis because it enables HIF-1/VEGF signaling that sustains... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
We screened 79 acute myeloid leukemia (AML) cell lines and found five positive for JAK2 V617F (HEL, ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Human breast cancer database analysis revealed that increased expression (greater than the median) o... DisGeNET Detail
Endometral carcinoma is the most common malignant tumor of the female genital tract and the fourth m... DisGeNET Detail
In addition, PA-12 blocked the nuclear translocalization of PKM2 in lung cancer cells, resulting in ... DisGeNET Detail
FOXP1 expression was significantly correlated with the expression of HIF1 and VEGF (r=0.54, p<0.01 a... DisGeNET Detail
Colon cancer cell response to the BH3-mimetic was unmodified by HIF-1 activation and OBX induced a d... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Hypoxia-inducible factor-1 (HIF-1) is one of the most promising pharmacological targets for all type... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Genes in histone modification [BAP1 (n = 6; 13%), SETD2 (n = 5; 11%), ASXL1 (n = 2; 4%)], chromatin ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
During tumor progression, hypoxia-inducible factor 1 (HIF-1) plays a critical role in tumor angiogen... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
In this study, we aimed to investigate the association between HIF-1 1772 C/T polymorphisms and endo... DisGeNET Detail
We also summarized the latest findings concerning the role of HIF-1 in the development of HCC, which... DisGeNET Detail
Hypoxia inducible factor-1 (HIF-1) is one of the key mediators of the hypoxia signaling pathway, and... DisGeNET Detail
Thus, NF-κB both positively and negatively fine-tuned HIF-1 in hypoxic hepatocarcinoma cells. DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
We used immunohistochemical staining of formalin-fixed paraffin-embedded BCC (n = 45) and TE (n = 35... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Human breast cancer database analysis revealed that increased expression (greater than the median) o... DisGeNET Detail
Colon cancer cell response to the BH3-mimetic was unmodified by HIF-1 activation and OBX induced a d... DisGeNET Detail
In this study, we aimed to investigate the association between HIF-1 1772 C/T polymorphisms and endo... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
MOTIF analysis of aberrantly hypermethylated regions revealed enrichment for binding sites of AP2a, ... DisGeNET Detail
PI3Kβ inhibitor TGX221 selectively inhibits renal cell carcinoma cells with both VHL and SETD2 mutat... DisGeNET Detail

Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
dbSNP
rs386626619 dbSNP
Genome
hg19
Position
chr3:47,057,918-47,205,603
Variant Type
snv
Genome browser