Annotation Detail
Information
- Associated Genes
- SETD2
- Associated Variants
-
SETD2 MUTATION
SETD2 MUTATION - Associated Disease
- liver carcinoma
- Source Database
- DisGeNET
- Description
- Hypoxia inducible factor-1 (HIF-1) is one of the key mediators of the hypoxia signaling pathway, and was recently proven to be required for sorafenib resistance in hepatocarcinoma (HCC).
- Pubmed
- 25531114
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00624316305784698
Drugs