Annotation Detail
Information
- Associated Genes
- SETD2
- Associated Variants
-
SETD2 MUTATION
SETD2 MUTATION - Associated Disease
- Adenocarcinoma of colon
- Source Database
- DisGeNET
- Description
- The BH3-mimetic obatoclax reduces HIF-1α levels and HIF-1 transcriptional activity and sensitizes hypoxic colon adenocarcinoma cells to 5-fluorouracil.
- Pubmed
- 25979228
- Section of the abstract supporting the evidence
- TITLE
- Number of the section of the abstract supporting the evidence
- 0
- Number of the sentence supporting the evidence
- 0
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs