chr4:85475150:> Detail (hg38)

Information

Genome

Assembly Position
hg19 chr4:86,396,303-86,923,821 
hg38 chr4:85,475,150-86,002,668

HGVS

Type Transcript Protein
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

[No Data.]

Prediction

[No Data.]

ClinVar

Clinical Significance
Review star [No Data.]
Show details
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score Disease name Description Source Pubmed Links
0.003 squamous cell carcinoma NA BeFree Detail
0.001 Malignant tumor of cervix NA BeFree Detail
0.005 colorectal carcinoma Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects aga... BeFree 26294215 Detail
<0.001 Colorectal Neoplasms NA BeFree Detail
<0.001 adenoid cystic carcinoma NA BeFree Detail
<0.001 Ependymoma NA BeFree Detail
<0.001 Esophageal Neoplasms p21 rs3176352 G>C and p73 rs1801173 C>T polymorphisms are associated with an inc... BeFree 24820515 Detail
<0.001 Fanconi anemia NA BeFree Detail
<0.001 gastritis NA BeFree Detail
<0.001 Gastrointestinal Neoplasms NA BeFree Detail
<0.001 glioblastoma NA BeFree Detail
<0.001 Glioma NA BeFree Detail
<0.001 Focal glomerulosclerosis NA BeFree Detail
<0.001 Graft-vs-Host Disease NA BeFree Detail
<0.001 hepatitis B NA BeFree Detail
<0.001 hepatitis C NA BeFree Detail
<0.001 Hunger NA BeFree Detail
<0.001 Kidney Diseases NA BeFree Detail
0.001 leukemia NA BeFree Detail
0.002 chronic lymphocytic leukemia NA BeFree Detail
<0.001 lymphoid leukemia NA BeFree Detail
0.002 Acute lymphocytic leukemia NA BeFree Detail
0.003 Leukemia, Myelocytic, Acute NA BeFree Detail
<0.001 myeloid leukemia NA BeFree Detail
<0.001 Myeloid Leukemia, Chronic NA BeFree Detail
<0.001 Leukemia, Myeloid, Chronic-Phase NA BeFree Detail
<0.001 acute promyelocytic leukemia NA BeFree Detail
<0.001 Leukoplakia NA BeFree Detail
<0.001 liver cirrhosis NA BeFree Detail
<0.001 Liver neoplasms NA BeFree Detail
0.004 lymphoma NA BeFree Detail
<0.001 Lymphoma, Non-Hodgkin NA BeFree Detail
<0.001 Lymphoproliferative Disorders NA BeFree Detail
0.001 Malignant neoplasm of stomach Our meta-analysis indicates that p73 G4A might not have a major effect on risk o... BeFree 25400764 Detail
<0.001 medulloblastoma NA BeFree Detail
0.002 melanoma NA BeFree Detail
0.001 meningioma NA BeFree Detail
<0.001 mitral valve stenosis NA BeFree Detail
<0.001 Mixed Salivary Gland Tumor NA BeFree Detail
0.001 multiple myeloma NA BeFree Detail
<0.001 multiple sclerosis NA BeFree Detail
<0.001 Nasal Polyps NA BeFree Detail
0.004 Neoplasm Metastasis We constructed oncolytic viruses armed with an inhibitor of deacetylation and/or... BeFree 25071017 Detail
0.004 Neoplasm Metastasis Restin suppressed epithelial-mesenchymal transition and tumor metastasis in brea... BeFree 25972084 Detail
0.009 neuroblastoma NA BeFree Detail
<0.001 Melanocytic nevus NA BeFree Detail
<0.001 oligodendroglioma NA BeFree Detail
<0.001 osteosarcoma NA BeFree Detail
0.004 ovarian carcinoma NA BeFree Detail
<0.001 Parathyroid Neoplasms NA BeFree Detail
<0.001 Precancerous Conditions NA BeFree Detail
<0.001 Preleukemia NA BeFree Detail
<0.001 retinoblastoma NA BeFree Detail
<0.001 Stomach Neoplasms NA BeFree Detail
<0.001 Thyroid Neoplasm NA BeFree Detail
0.002 Tobacco use disorder NA GAD Detail
<0.001 Vascular Diseases NA BeFree Detail
<0.001 B-Cell Lymphomas NA BeFree Detail
<0.001 diffuse large B-cell lymphoma NA BeFree Detail
<0.001 Lymphoma, Large-Cell, Follicular NA BeFree Detail
<0.001 T-Cell Lymphoma NA BeFree Detail
<0.001 Lymphoma, T-Cell, Cutaneous NA BeFree Detail
<0.001 acute leukemia NA BeFree Detail
<0.001 Epstein-Barr Virus Infections NA BeFree Detail
<0.001 Oral Cavity Carcinoma NA BeFree Detail
<0.001 Adenocarcinoma of lung (disorder) NA BeFree Detail
<0.001 esophageal carcinoma p21 rs3176352 G>C and p73 rs1801173 C>T polymorphisms are associated with an inc... BeFree 24820515 Detail
<0.001 Malignant neoplasm of mouth NA BeFree Detail
<0.001 Malignant neoplasm of oropharynx NA BeFree Detail
<0.001 Malignant neoplasm of gallbladder NA BeFree Detail
<0.001 Autoimmune thyroid disease NA BeFree Detail
0.002 Tumor Progression In parallel, although the tumor-suppressor p53 acts as the first barrier against... BeFree 26032560 Detail
<0.001 cholangiocarcinoma NA BeFree Detail
0.001 Lip and oral cavity carcinoma NA BeFree Detail
<0.001 gallbladder carcinoma NA BeFree Detail
<0.001 pancreatic carcinoma NA BeFree Detail
<0.001 Testicular embryonal carcinoma NA BeFree Detail
0.004 Malignant neoplasm of lung Treatment of cells with curcumin induced both p53 and the related protein p73 in... BeFree 25910231 Detail
<0.001 parathyroid adenoma NA BeFree Detail
<0.001 inflammatory breast carcinoma NA BeFree Detail
<0.001 Ovarian epithelial cancer stage III NA BeFree Detail
<0.001 gastric adenocarcinoma NA BeFree Detail
<0.001 Metastatic melanoma Eradication of metastatic melanoma through cooperative expression of RNA-based H... BeFree 25071017 Detail
<0.001 Cancer of Head and Neck NA BeFree Detail
<0.001 Squamous cell carcinoma of esophagus p21 rs3176352 G>C and p73 rs1801173 C>T SNPs are associated with increased risk ... BeFree 24820515 Detail
<0.001 Squamous cell carcinoma of esophagus The oncogene and tumor suppressor gene protein expression was related to the pro... BeFree 25622532 Detail
<0.001 Solid tumour NA BeFree Detail
<0.001 Squamous cell carcinoma of oropharynx NA BeFree Detail
0.001 cervix carcinoma NA BeFree Detail
<0.001 Segmental glomerulosclerosis NA BeFree Detail
<0.001 pilocytic astrocytoma NA BeFree Detail
<0.001 anaplastic oligodendroglioma NA BeFree Detail
<0.001 Human papilloma virus infection NA BeFree Detail
<0.001 Malignant neoplasm of pancreas NA BeFree Detail
<0.001 Disseminated Malignant Neoplasm We constructed oncolytic viruses armed with an inhibitor of deacetylation and/or... BeFree 25071017 Detail
0.001 Malignant neoplasm of prostate NA BeFree Detail
<0.001 Hematopoietic Neoplasms NA BeFree Detail
0.002 Hematologic Neoplasms NA BeFree Detail
0.120 Electrocardiogram: P-R interval NA GWASCAT Detail
<0.001 endometrial carcinoma NA BeFree Detail
0.001 Malignant neoplasm of esophagus p21 rs3176352 G>C and p73 rs1801173 C>T polymorphisms are associated with an inc... BeFree 24820515 Detail
<0.001 Recurrent Carcinoma NA BeFree Detail
0.001 Thyroid carcinoma NA BeFree Detail
<0.001 Squamous cell carcinoma of skin NA BeFree Detail
<0.001 Squamous cell carcinoma of mouth NA BeFree Detail
<0.001 Osteosarcoma of bone NA BeFree Detail
0.014 Carcinogenesis Thus, the impact of p73 on tumorigenesis depends on a subtle balance between tum... BeFree 24742294 Detail
0.014 Carcinogenesis The transcription factor p73 belongs to the p53-family and regulates tumorigenes... BeFree 25514460 Detail
<0.001 Leukemogenesis NA BeFree Detail
0.002 prostate carcinoma NA BeFree Detail
0.001 Epithelial ovarian cancer NA BeFree Detail
0.005 breast carcinoma Transcriptional regulation of the p73 gene by Nrf-2 and promoter CpG methylation... BeFree 25071010 Detail
0.005 breast carcinoma Restin suppressed epithelial-mesenchymal transition and tumor metastasis in brea... BeFree 25972084 Detail
0.004 Carcinoma of lung Treatment of cells with curcumin induced both p53 and the related protein p73 in... BeFree 25910231 Detail
0.001 Secondary malignant neoplasm of lymph node NA BeFree Detail
<0.001 colon carcinoma NA BeFree Detail
0.002 stomach carcinoma Our meta-analysis indicates that p73 G4A might not have a major effect on risk o... BeFree 25400764 Detail
0.002 Carcinoma of bladder NA BeFree Detail
0.008 Central neuroblastoma NA BeFree Detail
<0.001 Malignant neoplasm of kidney NA BeFree Detail
<0.001 Well Differentiated Oligodendroglioma NA BeFree Detail
<0.001 Malignant Squamous Cell Neoplasm NA BeFree Detail
<0.001 Helicobacter pylori infection NA BeFree Detail
0.002 Drug-Induced Liver Injury NA GAD Detail
<0.001 Borderline ovarian tumour NA BeFree Detail
<0.001 Intraepithelial Neoplasia NA BeFree Detail
<0.001 ovarian neoplasm NA BeFree Detail
<0.001 Ovarian adenocarcinoma NA BeFree Detail
0.003 Malignant neoplasm of ovary NA BeFree Detail
0.001 Squamous cell carcinoma of the head and neck NA BeFree Detail
<0.001 Precursor B-cell lymphoblastic leukemia NA BeFree Detail
<0.001 Sporadic Breast Carcinoma NA BeFree Detail
<0.001 differentiated thyroid gland carcinoma NA BeFree Detail
<0.001 renal carcinoma NA BeFree Detail
<0.001 Mammary Neoplasms NA BeFree Detail
<0.001 Autism Spectrum Disorders NA BeFree Detail
<0.001 Hepatocarcinogenesis NA BeFree Detail
<0.001 Tumor Angiogenesis NA BeFree Detail
0.004 colorectal cancer Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects aga... BeFree 26294215 Detail
<0.001 Cirrhosis NA BeFree Detail
<0.001 androgen independent prostate cancer NA BeFree Detail
<0.001 Meningioma, benign, no ICD-O subtype NA BeFree Detail
<0.001 uterine corpus cancer NA BeFree Detail
0.004 Precursor Cell Lymphoblastic Leukemia Lymphoma NA BeFree,GAD Detail
0.005 liver carcinoma Piper betle leaf extracts induced human hepatocellular carcinoma Hep3B cell deat... BeFree 25371988 Detail
<0.001 Oropharyngeal Carcinoma NA BeFree Detail
<0.001 XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP C NA BeFree Detail
<0.001 Nasopharyngeal carcinoma NA BeFree Detail
<0.001 GASTRIC CANCER, INTESTINAL NA BeFree Detail
<0.001 myelodysplastic syndrome NA BeFree Detail
<0.001 FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) NA BeFree Detail
<0.001 Triple Negative Breast Neoplasms Together, these results indicate that activation of a RASAL2/ARHGAP24/RAC1 modul... BeFree 25384218 Detail
<0.001 Allergic disposition NA BeFree Detail
0.001 adenocarcinoma NA BeFree Detail
<0.001 adenoma NA BeFree Detail
<0.001 Alzheimer's disease NA BeFree Detail
<0.001 arteriosclerosis NA BeFree Detail
<0.001 Astrocytoma NA BeFree Detail
<0.001 atherosclerosis NA BeFree Detail
0.002 Malignant neoplasm of urinary bladder NA BeFree Detail
<0.001 Blast Phase NA BeFree Detail
<0.001 Brain Neoplasms NA BeFree Detail
0.005 Malignant neoplasm of breast Transcriptional regulation of the p73 gene by Nrf-2 and promoter CpG methylation... BeFree 25071010 Detail
0.005 Malignant neoplasm of breast Restin suppressed epithelial-mesenchymal transition and tumor metastasis in brea... BeFree 25972084 Detail
<0.001 Malignant tumor of colon NA BeFree Detail
<0.001 Malignant neoplasm of endometrium NA BeFree Detail
<0.001 Rectal Carcinoma NA BeFree Detail
0.001 Malignant neoplasm of thyroid NA BeFree Detail
<0.001 Bronchogenic Carcinoma NA BeFree Detail
<0.001 Merkel cell carcinoma NA BeFree Detail
0.002 Non-small cell lung carcinoma Association between a p73 gene polymorphism and genetic susceptibility to non-sm... BeFree 25556480 Detail
<0.001 renal cell carcinoma NA BeFree Detail
Annotation

Annotations

DescrptionSourceLinks
NA DisGeNET Detail
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Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Canc... DisGeNET Detail
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p21 rs3176352 G>C and p73 rs1801173 C>T polymorphisms are associated with an increased risk of esoph... DisGeNET Detail
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Our meta-analysis indicates that p73 G4A might not have a major effect on risk of gastric cancer. DisGeNET Detail
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We constructed oncolytic viruses armed with an inhibitor of deacetylation and/or p73 to specifically... DisGeNET Detail
Restin suppressed epithelial-mesenchymal transition and tumor metastasis in breast cancer cells thro... DisGeNET Detail
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p21 rs3176352 G>C and p73 rs1801173 C>T polymorphisms are associated with an increased risk of esoph... DisGeNET Detail
NA DisGeNET Detail
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In parallel, although the tumor-suppressor p53 acts as the first barrier against tumor transformatio... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
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NA DisGeNET Detail
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Treatment of cells with curcumin induced both p53 and the related protein p73 in head and neck and l... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Eradication of metastatic melanoma through cooperative expression of RNA-based HDAC1 inhibitor and p... DisGeNET Detail
NA DisGeNET Detail
p21 rs3176352 G>C and p73 rs1801173 C>T SNPs are associated with increased risk of ESCC. DisGeNET Detail
The oncogene and tumor suppressor gene protein expression was related to the prognostic factor, and ... DisGeNET Detail
NA DisGeNET Detail
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We constructed oncolytic viruses armed with an inhibitor of deacetylation and/or p73 to specifically... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
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p21 rs3176352 G>C and p73 rs1801173 C>T polymorphisms are associated with an increased risk of esoph... DisGeNET Detail
NA DisGeNET Detail
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Thus, the impact of p73 on tumorigenesis depends on a subtle balance between tumor-promoting and -su... DisGeNET Detail
The transcription factor p73 belongs to the p53-family and regulates tumorigenesis via its two N-ter... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Transcriptional regulation of the p73 gene by Nrf-2 and promoter CpG methylation in human breast can... DisGeNET Detail
Restin suppressed epithelial-mesenchymal transition and tumor metastasis in breast cancer cells thro... DisGeNET Detail
Treatment of cells with curcumin induced both p53 and the related protein p73 in head and neck and l... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Our meta-analysis indicates that p73 G4A might not have a major effect on risk of gastric cancer. DisGeNET Detail
NA DisGeNET Detail
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Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Canc... DisGeNET Detail
NA DisGeNET Detail
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NA DisGeNET Detail
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Piper betle leaf extracts induced human hepatocellular carcinoma Hep3B cell death via MAPKs regulati... DisGeNET Detail
NA DisGeNET Detail
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Together, these results indicate that activation of a RASAL2/ARHGAP24/RAC1 module contributes to TNB... DisGeNET Detail
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Transcriptional regulation of the p73 gene by Nrf-2 and promoter CpG methylation in human breast can... DisGeNET Detail
Restin suppressed epithelial-mesenchymal transition and tumor metastasis in breast cancer cells thro... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
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Association between a p73 gene polymorphism and genetic susceptibility to non-small cell lung cancer... DisGeNET Detail
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Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
Genome
hg38
Position
chr4:85,475,150-86,002,668
Variant Type
snv
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