chr14:20455191:> Detail (hg38)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr14:20,923,350-20,925,931 |
| hg38 | chr14:20,455,191-20,457,772 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
| Score | Disease name | Description | Source | Pubmed | Links |
|---|---|---|---|---|---|
| <0.001 | squamous cell carcinoma | NA | BeFree | Detail | |
| 0.080 | brain ischemia | NA | RGD | Detail | |
| <0.001 | Malignant tumor of cervix | NA | BeFree | Detail | |
| 0.005 | Uterine Cervical Neoplasm | NA | GAD,LHGDN | Detail | |
| <0.001 | Primary biliary cirrhosis | NA | BeFree | Detail | |
| 0.002 | Chromosome Aberrations | NA | GAD | Detail | |
| 0.003 | Cockayne syndrome | NA | LHGDN | Detail | |
| <0.001 | ulcerative colitis | NA | BeFree | Detail | |
| 0.008 | Colorectal Neoplasms | NA | GAD,LHGDN | Detail | |
| <0.001 | Coronary heart disease | NA | BeFree | Detail | |
| 0.009 | DNA Damage | NA | GAD | Detail | |
| <0.001 | Muscular Dystrophy, Duchenne | NA | BeFree | Detail | |
| <0.001 | Epilepsy, Temporal Lobe | NA | BeFree | Detail | |
| 0.005 | Esophageal Neoplasms | NA | BeFree,GAD | Detail | |
| <0.001 | gastritis | NA | BeFree | Detail | |
| <0.001 | glioblastoma | APE1/REF-1 down-regulation enhances the cytotoxic effects of temozolomide in a r... | BeFree | 26520369 | Detail |
| 0.014 | Glioma | NA | BeFree,GAD,LHGDN | Detail | |
| 0.002 | Graft-vs-Host Disease | NA | GAD | Detail | |
| 0.002 | Head and Neck Neoplasms | NA | GAD | Detail | |
| 0.120 | Heart Diseases | NA | CTD_human | Detail | |
| <0.001 | HIV Infections | NA | BeFree | Detail | |
| <0.001 | Hodgkin Disease | NA | BeFree | Detail | |
| <0.001 | Huntington disease | NA | BeFree | Detail | |
| 0.003 | Hyperplasia | NA | LHGDN | Detail | |
| <0.001 | Hypertensive disease | NA | BeFree | Detail | |
| <0.001 | male infertility | NA | BeFree | Detail | |
| <0.001 | keratosis | NA | BeFree | Detail | |
| 0.003 | Kidney Diseases | We have reported a possible involvement of apurinic/apyrimidinic endonuclease 1 ... | BeFree,GAD | 25363496 | Detail |
| 0.002 | Laryngeal neoplasm | NA | GAD | Detail | |
| <0.001 | Fibroid Tumor | NA | BeFree | Detail | |
| <0.001 | leiomyosarcoma | NA | BeFree | Detail | |
| <0.001 | leptospirosis | NA | BeFree | Detail | |
| 0.011 | leukemia | NA | BeFree,GAD,LHGDN | Detail | |
| <0.001 | Leukemia, Myelocytic, Acute | NA | BeFree | Detail | |
| 0.002 | myeloid leukemia | NA | GAD | Detail | |
| <0.001 | Liver diseases | NA | BeFree | Detail | |
| 0.080 | Lung diseases | NA | RGD | Detail | |
| 0.002 | Chronic Obstructive Airway Disease | NA | GAD | Detail | |
| 0.011 | Lung Neoplasms | NA | BeFree,LHGDN | Detail | |
| 0.002 | Lymphatic Metastasis | NA | GAD | Detail | |
| 0.002 | Lymphoma, Follicular | NA | GAD | Detail | |
| 0.134 | melanoma | NA | BeFree,CTD_human,GAD,LHGDN | Detail | |
| <0.001 | Melanosis | NA | BeFree | Detail | |
| 0.002 | Meningeal Neoplasms | NA | GAD | Detail | |
| 0.002 | meningioma | NA | GAD | Detail | |
| <0.001 | meningitis | NA | BeFree | Detail | |
| <0.001 | aseptic meningitis | NA | BeFree | Detail | |
| 0.002 | Mouth Neoplasms | NA | GAD | Detail | |
| 0.004 | multiple myeloma | NA | BeFree,LHGDN | Detail | |
| 0.002 | multiple sclerosis | NA | GAD | Detail | |
| 0.005 | myocardial infarction | NA | BeFree,GAD,LHGDN | Detail | |
| 0.080 | Myocardial Reperfusion Injury | NA | RGD | Detail | |
| 0.004 | Neoplasm Metastasis | NA | BeFree,LHGDN | Detail | |
| 0.002 | Neural Tube Defects | NA | GAD | Detail | |
| 0.002 | acoustic neuroma | NA | GAD | Detail | |
| <0.001 | osteoporosis | NA | BeFree | Detail | |
| 0.005 | osteosarcoma | Apurinic/apyrimidinic endonuclease 1 regulates angiogenesis in a transforming gr... | BeFree,LHGDN | 26250694 | Detail |
| 0.001 | ovarian carcinoma | NA | BeFree | Detail | |
| 0.003 | Pancreatic Neoplasm | NA | LHGDN | Detail | |
| 0.002 | Pharyngeal Neoplasms | NA | GAD | Detail | |
| <0.001 | pneumonia | NA | BeFree | Detail | |
| 0.002 | Adenomatous Polyposis Coli | NA | GAD | Detail | |
| 0.002 | pre-eclampsia | NA | GAD | Detail | |
| 0.002 | Precancerous Conditions | NA | GAD | Detail | |
| 0.120 | Prostatic Neoplasms | NA | CTD_human | Detail | |
| 0.003 | pterygium | NA | BeFree,GAD | Detail | |
| 0.080 | Reperfusion Injury | NA | RGD | Detail | |
| <0.001 | retinoblastoma | NA | BeFree | Detail | |
| 0.200 | Seizures | NA | CTD_human,RGD | Detail | |
| <0.001 | seminoma | NA | BeFree | Detail | |
| <0.001 | Age-related cataract | The changes of 8-OHdG, hOGG1, APE1 and Pol β in lenses of patients with age-rela... | BeFree | 24911554 | Detail |
| 0.005 | Skin Neoplasms | NA | GAD | Detail | |
| <0.001 | hereditary spherocytosis | NA | BeFree | Detail | |
| 0.080 | status epilepticus | NA | RGD | Detail | |
| 0.127 | Stomach Neoplasms | NA | CTD_human,GAD | Detail | |
| 0.008 | Cerebrovascular accident | NA | BeFree,GAD,LHGDN | Detail | |
| 0.005 | Thyroid Neoplasm | NA | GAD,LHGDN | Detail | |
| <0.001 | Trisomy | NA | BeFree | Detail | |
| <0.001 | Uterine Fibroids | NA | BeFree | Detail | |
| <0.001 | vitiligo | NA | BeFree | Detail | |
| 0.002 | Helicobacter Infections | NA | GAD | Detail | |
| 0.002 | diffuse large B-cell lymphoma | NA | GAD | Detail | |
| <0.001 | Meningitis, Bacterial | In recent papers published by our group, we described the associations between t... | BeFree | 26316174 | Detail |
| <0.001 | essential hypertension | NA | BeFree | Detail | |
| <0.001 | cataract | NA | BeFree | Detail | |
| <0.001 | Gastric adenoma | NA | BeFree | Detail | |
| <0.001 | Migraine Disorders | Our findings have suggested that APE1, XRCC3, XPD, and hOGG1 gene variants could... | BeFree | 24892639 | Detail |
| <0.001 | Cutaneous Melanoma | NA | BeFree | Detail | |
| 0.001 | Adenocarcinoma of lung (disorder) | NA | BeFree | Detail | |
| <0.001 | esophageal carcinoma | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of testis | NA | BeFree | Detail | |
| <0.001 | Smith-Lemli-Opitz syndrome | NA | BeFree | Detail | |
| <0.001 | Germ cell tumor | NA | BeFree | Detail | |
| 0.003 | alveolar rhabdomyosarcoma | NA | BeFree,LHGDN | Detail | |
| 0.003 | Rhabdomyosarcoma, Embryonal | NA | LHGDN | Detail | |
| <0.001 | smooth muscle tumor | NA | BeFree | Detail | |
| <0.001 | Melanosis coli | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of female breast | Germline variations of apurinic/apyrimidinic endonuclease 1 (APEX1) detected in ... | BeFree | 25292033 | Detail |
| 0.001 | pancreatic carcinoma | NA | BeFree | Detail | |
| <0.001 | Pick Disease of the Brain | NA | BeFree | Detail | |
| 0.049 | Malignant neoplasm of lung | Evaluating the association of polymorphisms in the HAP1 gene with lung cancer ri... | BeFree,GAD | 25081373 | Detail |
| 0.049 | Malignant neoplasm of lung | The interaction of APEX1 variant with polycyclic aromatic hydrocarbons on increa... | BeFree,GAD | 25156607 | Detail |
| 0.049 | Malignant neoplasm of lung | Development of APE1 enzymatic DNA repair assays: low APE1 activity is associated... | BeFree,GAD | 26045303 | Detail |
| <0.001 | Parkinsonian Disorders | NA | BeFree | Detail | |
| 0.120 | Disease Progression | NA | CTD_human | Detail | |
| <0.001 | Xeroderma Pigmentosum, Complementation Group D | NA | BeFree | Detail | |
| <0.001 | gastric adenocarcinoma | NA | BeFree | Detail | |
| <0.001 | Malignant Childhood Neoplasm | NA | BeFree | Detail | |
| <0.001 | intraocular retinoblastoma | NA | BeFree | Detail | |
| <0.001 | Liver and Intrahepatic Biliary Tract Carcinoma | NA | BeFree | Detail | |
| <0.001 | Squamous cell carcinoma of esophagus | NA | BeFree | Detail | |
| <0.001 | Solid tumour | NA | BeFree | Detail | |
| 0.003 | cervix carcinoma | NA | BeFree,GAD | Detail | |
| 0.002 | Arsenic Poisoning | NA | GAD | Detail | |
| <0.001 | Teratoma, Malignant | NA | BeFree | Detail | |
| <0.001 | frontotemporal dementia | NA | BeFree | Detail | |
| <0.001 | Amnesia, Transient Global | NA | BeFree | Detail | |
| <0.001 | Ocular albinism, type I | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of liver | NA | BeFree | Detail | |
| 0.006 | Malignant neoplasm of pancreas | NA | BeFree,GAD | Detail | |
| <0.001 | Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site | NA | BeFree | Detail | |
| 0.002 | Hematologic Neoplasms | NA | GAD | Detail | |
| <0.001 | Familial aplasia of the vermis | NA | BeFree | Detail | |
| <0.001 | endometrial carcinoma | NA | BeFree | Detail | |
| <0.001 | Overweight | NA | BeFree | Detail | |
| <0.001 | Neurodegenerative Disorders | NA | BeFree | Detail | |
| <0.001 | Environmental Carcinogenesis | Human AP endonuclease 1: a potential marker for the prediction of environmental ... | BeFree | 25243052 | Detail |
| <0.001 | Malignant neoplasm of esophagus | NA | BeFree | Detail | |
| 0.002 | Osteosarcoma of bone | Apurinic/apyrimidinic endonuclease 1 regulates angiogenesis in a transforming gr... | BeFree | 26250694 | Detail |
| <0.001 | Intraocular pressure disorder | Gene-based analysis found suggestive associations between IOP and the genes HAP1... | BeFree | 25525164 | Detail |
| 0.003 | Carcinogenesis | In summary, our data show that patients with colorectal cancer present expressio... | BeFree | 25268610 | Detail |
| 0.002 | subcutaneous fibrosis | NA | GAD | Detail | |
| <0.001 | hyperhomocysteinemia | NA | BeFree | Detail | |
| 0.002 | Epithelial ovarian cancer | NA | GAD | Detail | |
| 0.005 | breast carcinoma | In conclusion, our study demonstrates a significant association between germ lin... | BeFree | 25292033 | Detail |
| 0.005 | breast carcinoma | HAP1 gene expression is associated with radiosensitivity in breast cancer cells. | BeFree | 25446120 | Detail |
| 0.009 | Carcinoma of lung | Evaluating the association of polymorphisms in the HAP1 gene with lung cancer ri... | BeFree | 25081373 | Detail |
| 0.009 | Carcinoma of lung | The interaction of APEX1 variant with polycyclic aromatic hydrocarbons on increa... | BeFree | 25156607 | Detail |
| 0.009 | Carcinoma of lung | Development of APE1 enzymatic DNA repair assays: low APE1 activity is associated... | BeFree | 26045303 | Detail |
| <0.001 | Secondary malignant neoplasm of lymph node | NA | BeFree | Detail | |
| <0.001 | colon carcinoma | NA | BeFree | Detail | |
| 0.002 | Carcinoma of bladder | NA | BeFree | Detail | |
| <0.001 | biliary tract cancer | NA | BeFree | Detail | |
| 0.001 | Helicobacter pylori infection | NA | BeFree | Detail | |
| <0.001 | Testicular malignant germ cell tumor | NA | BeFree | Detail | |
| <0.001 | Hyperkeratosis | NA | BeFree | Detail | |
| <0.001 | Carcinoma, Pancreatic Ductal | In recent years, Ref-1 has emerged as a promising therapeutic target in cancer, ... | BeFree | 25492865 | Detail |
| 0.003 | ovarian neoplasm | NA | BeFree,LHGDN | Detail | |
| 0.002 | Papillomavirus Infections | NA | GAD | Detail | |
| <0.001 | Malignant neoplasm of ovary | NA | BeFree | Detail | |
| <0.001 | Squamous cell carcinoma of the head and neck | NA | BeFree | Detail | |
| <0.001 | Adenoma of large intestine | NA | BeFree | Detail | |
| <0.001 | Pediatric Intraocular Retinoblastoma | NA | BeFree | Detail | |
| <0.001 | pancreatic ductal adenocarcinoma | In particular, we focused on understanding the implications of the novel interac... | BeFree | 25492865 | Detail |
| <0.001 | differentiated thyroid gland carcinoma | NA | BeFree | Detail | |
| 0.120 | Micronuclei, Chromosome-Defective | NA | CTD_human | Detail | |
| 0.008 | Mammary Neoplasms | NA | LHGDN | Detail | |
| <0.001 | Hepatocarcinogenesis | NA | BeFree | Detail | |
| <0.001 | Tumor Angiogenesis | It has been shown that apurinic/apyrimidinic endonuclease 1 (APE1), a dually fun... | BeFree | 26250694 | Detail |
| <0.001 | Tumor Promotion | NA | BeFree | Detail | |
| <0.001 | Xenograft Model | NA | BeFree | Detail | |
| <0.001 | Rash and Dermatitis Adverse Event Associated with Chemoradiation | NA | BeFree | Detail | |
| <0.001 | Hyperkeratosis | Data from a case-control study of 792 cases and 792 matched controls conducted i... | BeFree | 17374727 | Detail |
| <0.001 | Melanosis | Data from a case-control study of 792 cases and 792 matched controls conducted i... | BeFree | 17374727 | Detail |
| <0.001 | VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding) | NA | BeFree | Detail | |
| <0.001 | keratosis | Data from a case-control study of 792 cases and 792 matched controls conducted i... | BeFree | 17374727 | Detail |
| <0.001 | Amyotrophic Lateral Sclerosis, Sporadic | NA | BeFree | Detail | |
| <0.001 | uterine corpus cancer | NA | BeFree | Detail | |
| 0.002 | Malignant neoplasm of stomach | To evaluate the association between genetic polymorphisms of X-ray repair cross-... | BeFree | 19147860 | Detail |
| 0.125 | liver carcinoma | The role of APE/Ref-1 signaling pathway in hepatocellular carcinoma progression. | BeFree,CTD_human,LHGDN | 25109342 | Detail |
| 0.002 | stomach carcinoma | To evaluate the association between genetic polymorphisms of X-ray repair cross-... | BeFree | 19147860 | Detail |
| <0.001 | SPHEROCYTOSIS, TYPE 1 (disorder) | NA | BeFree | Detail | |
| 0.028 | Malignant neoplasm of urinary bladder | Using multifactor dimensionality reduction approach, the four-factor model, incl... | BeFree | 17220334 | Detail |
| 0.080 | Cerebral Hemorrhage | NA | RGD | Detail | |
| <0.001 | Early-Stage Breast Carcinoma | To test this hypothesis, we investigated 1406 ER(+) early-stage breast cancers w... | BeFree | 25111287 | Detail |
| <0.001 | Homocysteinemia | NA | BeFree | Detail | |
| 0.004 | Non-small cell lung carcinoma | Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G>C, 8... | BeFree | 16195237 | Detail |
| 0.003 | Infection | NA | LHGDN | Detail | |
| <0.001 | Melanosis coli | Data from a case-control study of 792 cases and 792 matched controls conducted i... | BeFree | 17374727 | Detail |
| <0.001 | Pneumonitis | NA | BeFree | Detail | |
| 0.002 | Carcinoma of bladder | Using multifactor dimensionality reduction approach, the four-factor model, incl... | BeFree | 17220334 | Detail |
| 0.008 | adenocarcinoma | NA | BeFree,GAD,LHGDN | Detail | |
| <0.001 | adenoma | NA | BeFree | Detail | |
| <0.001 | AIDS related complex | To evaluate the changes of oxidative DNA damage (in the form of 8-OHdG) and thre... | BeFree | 24911554 | Detail |
| 0.003 | Alzheimer's disease | NA | BeFree,GAD | Detail | |
| 0.004 | amyotrophic lateral sclerosis | NA | BeFree,LHGDN | Detail | |
| <0.001 | arteriosclerosis | NA | BeFree | Detail | |
| <0.001 | atherosclerosis | NA | BeFree | Detail | |
| 0.049 | Malignant neoplasm of lung | In conclusion, the APE1 Asp148Glu polymorphism is highly predictive for lung can... | BeFree | 17531525 | Detail |
| <0.001 | Rash and Dermatitis Adverse Event Associated with Chemoradiation | We genotyped SNPs of ADPRT (rs1136410 [V762A]), XRCC1 (rs1799782 [R194W], rs2548... | BeFree | 21420246 | Detail |
| 0.009 | Carcinoma of lung | In conclusion, the APE1 Asp148Glu polymorphism is highly predictive for lung can... | BeFree | 17531525 | Detail |
| 0.009 | Carcinoma of lung | These results suggest that APE1 Asp148Glu and XRCC1 Arg399Gln polymorphisms migh... | BeFree | 15044328 | Detail |
| 0.049 | Malignant neoplasm of lung | These results suggest that APE1 Asp148Glu and XRCC1 Arg399Gln polymorphisms migh... | BeFree | 15044328 | Detail |
| 0.002 | Biliary Tract Neoplasm | NA | GAD | Detail | |
| 0.028 | Malignant neoplasm of urinary bladder | NA | BeFree,GAD | Detail | |
| 0.005 | Brain Neoplasms | NA | BeFree,GAD | Detail | |
| 0.019 | Malignant neoplasm of breast | In conclusion, our study demonstrates a significant association between germ lin... | BeFree,GAD | 25292033 | Detail |
| 0.019 | Malignant neoplasm of breast | HAP1 gene expression is associated with radiosensitivity in breast cancer cells. | BeFree,GAD | 25446120 | Detail |
| <0.001 | Malignant tumor of colon | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of endometrium | NA | BeFree | Detail | |
| <0.001 | female breast carcinoma | Germline variations of apurinic/apyrimidinic endonuclease 1 (APEX1) detected in ... | BeFree | 25292033 | Detail |
| 0.004 | Non-small cell lung carcinoma | In addition, utilizing human non-small-cell lung cancer sample tissue as well as... | BeFree | 25452143 | Detail |
| <0.001 | renal cell carcinoma | NA | BeFree | Detail |
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| APE1/REF-1 down-regulation enhances the cytotoxic effects of temozolomide in a resistant glioblastom... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| We have reported a possible involvement of apurinic/apyrimidinic endonuclease 1 (APE1), one of the D... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
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| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Apurinic/apyrimidinic endonuclease 1 regulates angiogenesis in a transforming growth factor β-depend... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The changes of 8-OHdG, hOGG1, APE1 and Pol β in lenses of patients with age-related cataract. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In recent papers published by our group, we described the associations between the single nucleotide... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Our findings have suggested that APE1, XRCC3, XPD, and hOGG1 gene variants could facilitate the deve... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Germline variations of apurinic/apyrimidinic endonuclease 1 (APEX1) detected in female breast cancer... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Evaluating the association of polymorphisms in the HAP1 gene with lung cancer risk: a meta-analysis. | DisGeNET | Detail |
| The interaction of APEX1 variant with polycyclic aromatic hydrocarbons on increasing chromosome dama... | DisGeNET | Detail |
| Development of APE1 enzymatic DNA repair assays: low APE1 activity is associated with increase lung ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Human AP endonuclease 1: a potential marker for the prediction of environmental carcinogenesis risk. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Apurinic/apyrimidinic endonuclease 1 regulates angiogenesis in a transforming growth factor β-depend... | DisGeNET | Detail |
| Gene-based analysis found suggestive associations between IOP and the genes HAP1, MTBP, FREM3, and P... | DisGeNET | Detail |
| In summary, our data show that patients with colorectal cancer present expression changes in several... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In conclusion, our study demonstrates a significant association between germ line APEX1 mutations an... | DisGeNET | Detail |
| HAP1 gene expression is associated with radiosensitivity in breast cancer cells. | DisGeNET | Detail |
| Evaluating the association of polymorphisms in the HAP1 gene with lung cancer risk: a meta-analysis. | DisGeNET | Detail |
| The interaction of APEX1 variant with polycyclic aromatic hydrocarbons on increasing chromosome dama... | DisGeNET | Detail |
| Development of APE1 enzymatic DNA repair assays: low APE1 activity is associated with increase lung ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In recent years, Ref-1 has emerged as a promising therapeutic target in cancer, particularly in panc... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In particular, we focused on understanding the implications of the novel interaction between these t... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| It has been shown that apurinic/apyrimidinic endonuclease 1 (APE1), a dually functional protein poss... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... | DisGeNET | Detail |
| Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| To evaluate the association between genetic polymorphisms of X-ray repair cross-complementing group ... | DisGeNET | Detail |
| The role of APE/Ref-1 signaling pathway in hepatocellular carcinoma progression. | DisGeNET | Detail |
| To evaluate the association between genetic polymorphisms of X-ray repair cross-complementing group ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Using multifactor dimensionality reduction approach, the four-factor model, including smoking status... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| To test this hypothesis, we investigated 1406 ER(+) early-stage breast cancers with 20 years' long-t... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Our results indicate that SNPs in the NER genes ERCC1 (Asn118Asn, 15310G>C, 8902G>T), XPA (-4G... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Data from a case-control study of 792 cases and 792 matched controls conducted in Bangladesh from 20... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Using multifactor dimensionality reduction approach, the four-factor model, including smoking status... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| To evaluate the changes of oxidative DNA damage (in the form of 8-OHdG) and three key DNA base-excis... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In conclusion, the APE1 Asp148Glu polymorphism is highly predictive for lung cancer, and cumulative ... | DisGeNET | Detail |
| We genotyped SNPs of ADPRT (rs1136410 [V762A]), XRCC1 (rs1799782 [R194W], rs25489 [R280H], and rs254... | DisGeNET | Detail |
| In conclusion, the APE1 Asp148Glu polymorphism is highly predictive for lung cancer, and cumulative ... | DisGeNET | Detail |
| These results suggest that APE1 Asp148Glu and XRCC1 Arg399Gln polymorphisms might modify the risk of... | DisGeNET | Detail |
| These results suggest that APE1 Asp148Glu and XRCC1 Arg399Gln polymorphisms might modify the risk of... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In conclusion, our study demonstrates a significant association between germ line APEX1 mutations an... | DisGeNET | Detail |
| HAP1 gene expression is associated with radiosensitivity in breast cancer cells. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Germline variations of apurinic/apyrimidinic endonuclease 1 (APEX1) detected in female breast cancer... | DisGeNET | Detail |
| In addition, utilizing human non-small-cell lung cancer sample tissue as well as a nude mouse xenogr... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- dbSNP
- rs3136820 dbSNP
- Genome
- hg38
- Position
- chr14:20,455,191-20,457,772
- Variant Type
- snv
Genome browser