Annotation Detail
Information
- Associated Genes
- APEX1
- Associated Variants
-
APEX1 MUTATION
APEX1 MUTATION - Associated Disease
- Kidney Diseases
- Source Database
- DisGeNET
- Description
- We have reported a possible involvement of apurinic/apyrimidinic endonuclease 1 (APE1), one of the DNA repair pathways, in various nephropathy models and found that there is a close connection between APE1 and p53-dependent apoptosis.
- Pubmed
- 25363496
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 1
- Original source reporting the Gene Disease association
- BeFree,GAD
- DisGENET score for the Gene Disease association
- 0.00263847385068233
Drugs