Annotation Detail
Information
- Associated Genes
- APEX1
- Associated Variants
-
APEX1 MUTATION
APEX1 MUTATION - Associated Disease
- AIDS related complex
- Source Database
- DisGeNET
- Description
- To evaluate the changes of oxidative DNA damage (in the form of 8-OHdG) and three key DNA base-excision repair (BER) proteins, human 8-oxoguanine DNA glycosylase 1 (hOGG1), apurinic/apyrimidinic endonuclease 1 (APE1) and DNA polymerase β (Pol β), in lens epithelium cells (LECs), cortex and nucleus of lenses with age-related cataract (ARC) and age-matched controls.
- Pubmed
- 24911554
- Section of the abstract supporting the evidence
- PURPOSE
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 1
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs