Annotation Detail
Information
- Associated Genes
- APEX1
- Associated Variants
-
APEX1 MUTATION
APEX1 MUTATION - Associated Disease
- pancreatic ductal adenocarcinoma
- Source Database
- DisGeNET
- Description
- In particular, we focused on understanding the implications of the novel interaction between these two pathways in primary pancreatic ductal adenocarcinoma tumor cells and provide the first evidence that this mechanism has implications for overcoming the resistance against experimental drugs targeting Ref-1 activity, with clear translational implications.
- Pubmed
- 25492865
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs