Annotation Detail
Information
- Associated Genes
- APEX1
- Associated Variants
-
APEX1 MUTATION
APEX1 MUTATION - Associated Disease
- Tumor Angiogenesis
- Source Database
- DisGeNET
- Description
- It has been shown that apurinic/apyrimidinic endonuclease 1 (APE1), a dually functional protein possessing both base excision repair and redox activities, is involved in tumor angiogenesis, although these mechanisms are not fully understood.
- Pubmed
- 26250694
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
Drugs