chr9:128149071:> Detail (hg38)

Information

Genome

Assembly Position
hg19 chr9:130,911,350-130,915,732 
hg38 chr9:128,149,071-128,153,453

HGVS

Type Transcript Protein
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

[No Data.]

Prediction

[No Data.]

ClinVar

Clinical Significance
Review star [No Data.]
Show details
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score Disease name Description Source Pubmed Links
<0.001 squamous cell carcinoma NA BeFree Detail
0.001 Malignant tumor of cervix NA BeFree Detail
<0.001 choriocarcinoma NA BeFree Detail
<0.001 colitis NA BeFree Detail
<0.001 ulcerative colitis NA BeFree Detail
0.083 Colonic Neoplasms NA LHGDN,RGD Detail
<0.001 colorectal carcinoma NA BeFree Detail
<0.001 Crohn Disease NA BeFree Detail
<0.001 Cyst NA BeFree Detail
0.120 contact dermatitis NA CTD_human Detail
<0.001 diabetes mellitus NA BeFree Detail
0.080 Diabetes Mellitus, Experimental NA RGD Detail
<0.001 Diabetes Mellitus, Insulin-Dependent NA BeFree Detail
<0.001 Diabetes Mellitus, Non-Insulin-Dependent NA BeFree Detail
0.080 Diabetic Nephropathy NA BeFree,RGD Detail
<0.001 diverticulitis NA BeFree Detail
<0.001 Experimental Autoimmune Encephalomyelitis NA BeFree Detail
<0.001 Fatty Liver NA BeFree Detail
<0.001 glioblastoma NA BeFree Detail
<0.001 Glioma NA BeFree Detail
0.003 IgA glomerulonephritis NA LHGDN Detail
<0.001 Heart failure NA BeFree Detail
<0.001 congestive heart failure NA BeFree Detail
0.120 heart valve disease NA CTD_human Detail
0.120 Hepatitis, Animal NA CTD_human Detail
0.001 HIV Infections NA BeFree Detail
<0.001 Hypertensive disease NA BeFree Detail
<0.001 pulmonary hypertension Up-regulated lipocalin-2 in pulmonary hypertension involving in pulmonary artery... BeFree 25076856 Detail
0.123 Inflammation NA CTD_human,LHGDN Detail
<0.001 Inflammatory Bowel Diseases NA BeFree Detail
<0.001 ischemia NA BeFree Detail
0.127 Kidney Diseases NA BeFree,CTD_human,LHGDN Detail
0.003 Kidney Failure, Acute Our findings suggest that neutrophils are the major source of circulating LCN2 i... BeFree 24599361 Detail
0.003 Kidney Failure, Acute As neutrophil gelatinase-associated lipocalin (NGAL) has been shown to predict a... BeFree 25611655 Detail
<0.001 Kidney Failure, Chronic NA BeFree Detail
0.003 Polycystic Kidney Diseases NA BeFree,LHGDN Detail
0.003 leukemia NA BeFree,LHGDN Detail
0.003 Leukemia, Myelocytic, Acute NA BeFree,LHGDN Detail
0.001 Myeloid Leukemia, Chronic NA BeFree Detail
<0.001 lichen planus NA BeFree Detail
<0.001 liver cirrhosis NA BeFree Detail
0.120 Liver Cirrhosis, Experimental NA CTD_human Detail
<0.001 Liver neoplasms NA BeFree Detail
<0.001 Lung diseases NA BeFree Detail
0.003 Lupus Erythematosus, Systemic NA LHGDN Detail
<0.001 multiple sclerosis NA BeFree Detail
0.003 myocardial infarction NA BeFree,LHGDN Detail
0.080 myocarditis NA BeFree,RGD Detail
0.003 Nasal Polyps NA BeFree,LHGDN Detail
0.127 Neoplasm Metastasis Because breast cancer patient survival inversely correlates with metastasis, we ... BeFree,CTD_human,LHGDN 24467226 Detail
0.127 Neoplasm Metastasis Neutrophil gelatinase-associated lipocalin (NGAL) and matrix metalloproteinase-9... BeFree,CTD_human,LHGDN 25542236 Detail
0.127 Neoplasm Metastasis Therefore, targeted inhibition of LCN2 may represent a therapeutic strategy to p... BeFree,CTD_human,LHGDN 25728945 Detail
<0.001 nervous system disorder NA BeFree Detail
0.083 obesity Plasma NGAL may play a role in the development of insulin resistance in GDM, and... BeFree,RGD 24530115 Detail
0.083 obesity Estrogen receptor (ER)α-regulated lipocalin 2 expression in adipose tissue links... BeFree,RGD 25468909 Detail
<0.001 Obesity, Morbid NA BeFree Detail
0.003 Degenerative polyarthritis NA LHGDN Detail
<0.001 ovarian carcinoma NA BeFree Detail
<0.001 Ovarian Diseases NA BeFree Detail
0.005 Pancreatic Neoplasm NA LHGDN Detail
<0.001 pancreatitis NA BeFree Detail
<0.001 Parakeratosis NA BeFree Detail
<0.001 peritonitis NA BeFree Detail
<0.001 Pneumococcal Infections NA BeFree Detail
<0.001 pneumonia NA BeFree Detail
<0.001 Lobar Pneumonia NA BeFree Detail
<0.001 polycythemia vera NA BeFree Detail
<0.001 Adenomatous Polyposis Coli NA BeFree Detail
<0.001 polyps NA BeFree Detail
<0.001 Precancerous Conditions NA BeFree Detail
<0.001 Prostatic Neoplasms NA BeFree Detail
<0.001 psoriasis NA BeFree Detail
0.001 kidney failure NA BeFree Detail
0.003 Reperfusion Injury NA LHGDN Detail
<0.001 Respiratory Tract Infections NA BeFree Detail
<0.001 Septicemia At the time of first sample collection in the ED, gene expression of Interleukin... BeFree 25343379 Detail
0.003 sialadenitis NA BeFree,LHGDN Detail
<0.001 Dermatologic disorders NA BeFree Detail
<0.001 Skin Neoplasms NA BeFree Detail
<0.001 Cerebrovascular accident NA BeFree Detail
<0.001 Thrombocythemia, Essential NA BeFree Detail
<0.001 ureteral obstruction NA BeFree Detail
<0.001 urinary tract infection Lipocalin 2 imparts selective pressure on bacterial growth in the bladder and is... BeFree 25398327 Detail
<0.001 severe combined immunodeficiency NA BeFree Detail
<0.001 gestational diabetes The changes of neutrophil gelatinase-associated lipocalin in plasma and its expr... BeFree 24530115 Detail
<0.001 Neurofibrillary degeneration (morphologic abnormality) NA BeFree Detail
<0.001 Polycystic Kidney, Autosomal Dominant NA BeFree Detail
<0.001 Acute appendicitis NOS (disorder) NA BeFree Detail
<0.001 Pancreatitis, Chronic NA BeFree Detail
<0.001 Adenocarcinoma of lung (disorder) Neutrophil gelatinase-associated lipocalin (NGAL) and matrix metalloproteinase-9... BeFree 25542236 Detail
<0.001 esophageal carcinoma NA BeFree Detail
<0.001 congenital heart disease In this study, we observed that the expression levels of Lcn2 were significantly... BeFree 25076856 Detail
<0.001 Malignant neoplasm of mouth NA BeFree Detail
0.001 Secondary malignant neoplasm of lung Overexpression of LCN2 in ESCC cells accelerated cell migration and invasion in ... BeFree 26190820 Detail
<0.001 acute myocardial infarction NA BeFree Detail
<0.001 Streptococcal pneumonia NA BeFree Detail
<0.001 Aortic Aneurysm, Abdominal NA BeFree Detail
0.002 Tumor Progression NA BeFree Detail
<0.001 cholangiocarcinoma NA BeFree Detail
<0.001 Cervical Intraepithelial Neoplasia NA BeFree Detail
<0.001 Lip and oral cavity carcinoma NA BeFree Detail
<0.001 Memory impairment NA BeFree Detail
0.001 pancreatic carcinoma NA BeFree Detail
<0.001 Anaplastic thyroid carcinoma NA BeFree Detail
<0.001 Fibrosis, Liver We identified a PPI network module associated with liver fibrosis that includes ... BeFree 25380136 Detail
<0.001 Malignant neoplasm of lung NA BeFree Detail
0.003 Azotemia NA BeFree,LHGDN Detail
<0.001 Sepsis At the time of first sample collection in the ED, gene expression of Interleukin... BeFree 25343379 Detail
<0.001 Infectious colitis NA BeFree Detail
<0.001 Squamous cell carcinoma of esophagus Functional analysis of the mRNA profile of neutrophil gelatinase‑associated lipo... BeFree 25109818 Detail
<0.001 Squamous cell carcinoma of esophagus Shortest path analyses in the protein-protein interaction network of NGAL (neutr... BeFree 25169543 Detail
<0.001 Squamous cell carcinoma of esophagus Lipocalin 2 promotes the migration and invasion of esophageal squamous cell carc... BeFree 26190820 Detail
0.001 Solid tumour NA BeFree Detail
<0.001 Adenocarcinoma of pancreas NA BeFree Detail
0.001 cervix carcinoma NA BeFree Detail
<0.001 Optic Atrophy, Autosomal Dominant NA BeFree Detail
<0.001 Impaired cognition NA BeFree Detail
<0.001 intrahepatic cholangiocarcinoma The downregulation of LCN2 expression was blunted when vitamin D receptor (VDR) ... BeFree 24939880 Detail
0.001 Malignant neoplasm of pancreas NA BeFree Detail
<0.001 Cervical intraepithelial neoplasia grade 1 NA BeFree Detail
<0.001 Cervical intraepithelial neoplasia grade 2 NA BeFree Detail
0.002 Malignant neoplasm of prostate Over-expression of lipocalin 2 promotes cell migration and invasion through acti... BeFree 25728945 Detail
<0.001 Hematologic Neoplasms By sandwich ELISA, serum and urinary LCN2 levels were measured in 36 patients wi... BeFree 24599361 Detail
<0.001 Non-alcoholic Fatty Liver Disease NA BeFree Detail
0.121 Chronic Kidney Insufficiency The inflammation-lipocalin 2 axis may contribute to the development of chronic k... BeFree,CTD_human 24235082 Detail
<0.001 endometrial carcinoma NA BeFree Detail
<0.001 Secondary malignant neoplasm of liver Targeting delivery of lipocalin 2-engineered mesenchymal stem cells to colon can... BeFree 25740061 Detail
<0.001 Overweight Plasma NGAL may play a role in the development of insulin resistance in GDM, and... BeFree 24530115 Detail
<0.001 Recurrent tumor NA BeFree Detail
<0.001 Neurodegenerative Disorders NA BeFree Detail
<0.001 Malignant neoplasm of esophagus NA BeFree Detail
<0.001 Thyroid carcinoma NA BeFree Detail
<0.001 Prerenal uremia syndrome NA BeFree Detail
0.004 Carcinogenesis It was recently reported that lipocalin 2 (Lcn2) is up-regulated in a wide array... BeFree 25076856 Detail
0.002 prostate carcinoma Over-expression of lipocalin 2 promotes cell migration and invasion through acti... BeFree 25728945 Detail
0.001 Myeloid Leukemia, Chronic LCN-2 mRNA showed a near 50-fold increase in expression, accompanied by down-reg... BeFree 21950422 Detail
<0.001 invasive cancer NA BeFree Detail
<0.001 Progressive Neoplastic Disease NA BeFree Detail
0.004 breast carcinoma This synergistic approach--coupling the CXCR4 axis blockade with Lcn2 silencing-... BeFree 24467226 Detail
0.004 breast carcinoma Estrogen receptor (ER)α-regulated lipocalin 2 expression in adipose tissue links... BeFree 25468909 Detail
<0.001 polycythemia vera LCN-2 mRNA showed a near 50-fold increase in expression, accompanied by down-reg... BeFree 21950422 Detail
<0.001 Carcinoma of lung NA BeFree Detail
<0.001 Secondary malignant neoplasm of lymph node NA BeFree Detail
<0.001 colon carcinoma Targeting delivery of lipocalin 2-engineered mesenchymal stem cells to colon can... BeFree 25740061 Detail
<0.001 Carcinoma of bladder Because the expression of lipocalin-2 (LCN2) was highly enhanced by promoter hyp... BeFree 24570342 Detail
<0.001 cervical cancer metastasis NA BeFree Detail
<0.001 Central nervous system lesion NA BeFree Detail
<0.001 Unverricht-Lundborg syndrome The degree of temporal changes of P25 and N35 in ULD was similar or even lower t... BeFree 25023721 Detail
<0.001 Endothelial dysfunction NA BeFree Detail
<0.001 Post MI NA BeFree Detail
0.120 Drug-Induced Liver Injury NA CTD_human Detail
<0.001 Carcinoma, Pancreatic Ductal NA BeFree Detail
<0.001 Renal ischaemia NA BeFree Detail
<0.001 Vascular inflammations NA BeFree Detail
<0.001 Tauopathies NA BeFree Detail
0.003 Malignant neoplasm of ovary NA BeFree,GAD Detail
<0.001 Mild cognitive disorder NA BeFree Detail
<0.001 Pancreatic intraepithelial neoplasia NA BeFree Detail
<0.001 Adenoma of large intestine NA BeFree Detail
<0.001 mesenchymal cell neoplasm NA BeFree Detail
<0.001 pancreatic ductal adenocarcinoma NA BeFree Detail
<0.001 Bacteroides fragilis infection in conditions classified elsewhere and of unspecified site NA BeFree Detail
0.008 Mammary Neoplasms NA BeFree,LHGDN Detail
<0.001 Hippocampal sclerosis NA BeFree Detail
<0.001 Hepatocarcinogenesis NA BeFree Detail
<0.001 Tumor Angiogenesis NA BeFree Detail
<0.001 Xenograft Model NA BeFree Detail
<0.001 colorectal cancer NA BeFree Detail
0.001 Chronic Kidney Diseases The inflammation-lipocalin 2 axis may contribute to the development of chronic k... BeFree 24235082 Detail
0.001 Chronic Kidney Diseases While urinary NGAL was greater in CKD than control subjects, exosomal NGAL mRNA ... BeFree 24918752 Detail
0.001 Chronic Kidney Diseases Albumin-creatinine ratio (ACR), 4 tubular injury biomarkers (interleukin 18 [IL-... BeFree 25921719 Detail
<0.001 Cold Ischemia NA BeFree Detail
0.003 Delayed Graft Function NA LHGDN Detail
<0.001 Cirrhosis NA BeFree Detail
<0.001 Severe Sepsis Sustained elevation of resistin, NGAL and IL-8 are associated with severe sepsis... BeFree 25343379 Detail
<0.001 uterine corpus cancer NA BeFree Detail
0.002 liver carcinoma NA BeFree Detail
<0.001 Chronic kidney disease stage 5 NA BeFree Detail
0.200 Acute kidney injury NA CTD_human,RGD Detail
<0.001 Progressive cGVHD NA BeFree Detail
<0.001 Triple Negative Breast Neoplasms NA BeFree Detail
<0.001 Experimental Organism Basal Cell Carcinoma NA BeFree Detail
<0.001 Anemia in malignant neoplastic disease NA BeFree Detail
<0.001 Cytogenetically normal acute myeloid leukemia NA BeFree Detail
0.002 Spontaneous abortion NA GAD Detail
0.004 adenocarcinoma NA BeFree,LHGDN Detail
<0.001 adenoma NA BeFree Detail
<0.001 Alzheimer's disease NA BeFree Detail
<0.001 amyotrophic lateral sclerosis NA BeFree Detail
<0.001 anemia NA BeFree Detail
<0.001 Cooley's anemia NA BeFree Detail
<0.001 Aneurysm NA BeFree Detail
<0.001 appendicitis NA BeFree Detail
<0.001 arteriosclerosis NA BeFree Detail
0.120 rheumatoid arthritis NA CTD_human Detail
<0.001 atherosclerosis NA BeFree Detail
<0.001 Bacterial Infections In patients without AKI and bacterial infection, at 1 week after SCT, the median... BeFree 24599361 Detail
<0.001 Pneumonia, Bacterial NA BeFree Detail
<0.001 bacteriuria In a human cohort of women with recurrent E. coli UTIs, urine LCN2 levels were a... BeFree 25398327 Detail
0.123 beta thalassemia NA BeFree,CTD_human,LHGDN Detail
<0.001 Malignant neoplasm of urinary bladder Because the expression of lipocalin-2 (LCN2) was highly enhanced by promoter hyp... BeFree 24570342 Detail
0.004 Malignant neoplasm of breast This synergistic approach--coupling the CXCR4 axis blockade with Lcn2 silencing-... BeFree 24467226 Detail
0.004 Malignant neoplasm of breast Estrogen receptor (ER)α-regulated lipocalin 2 expression in adipose tissue links... BeFree 25468909 Detail
<0.001 Breast Diseases NA BeFree Detail
0.120 calcinosis NA CTD_human Detail
<0.001 Malignant tumor of colon Targeting delivery of lipocalin 2-engineered mesenchymal stem cells to colon can... BeFree 25740061 Detail
<0.001 Malignant neoplasm of endometrium NA BeFree Detail
<0.001 Rectal Carcinoma NA BeFree Detail
<0.001 Malignant neoplasm of thyroid NA BeFree Detail
<0.001 renal cell carcinoma NA BeFree Detail
Annotation

Annotations

DescrptionSourceLinks
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Up-regulated lipocalin-2 in pulmonary hypertension involving in pulmonary artery SMC resistance to a... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
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NA DisGeNET Detail
Our findings suggest that neutrophils are the major source of circulating LCN2 in normal and infecte... DisGeNET Detail
As neutrophil gelatinase-associated lipocalin (NGAL) has been shown to predict acute renal failure, ... DisGeNET Detail
NA DisGeNET Detail
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Because breast cancer patient survival inversely correlates with metastasis, we engineered vehicles ... DisGeNET Detail
Neutrophil gelatinase-associated lipocalin (NGAL) and matrix metalloproteinase-9 (MMP-9) are protein... DisGeNET Detail
Therefore, targeted inhibition of LCN2 may represent a therapeutic strategy to prevent the metastasi... DisGeNET Detail
NA DisGeNET Detail
Plasma NGAL may play a role in the development of insulin resistance in GDM, and the high levels of ... DisGeNET Detail
Estrogen receptor (ER)α-regulated lipocalin 2 expression in adipose tissue links obesity with breast... DisGeNET Detail
NA DisGeNET Detail
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At the time of first sample collection in the ED, gene expression of Interleukin (IL)-10 and Neutrop... DisGeNET Detail
NA DisGeNET Detail
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Lipocalin 2 imparts selective pressure on bacterial growth in the bladder and is elevated in women w... DisGeNET Detail
NA DisGeNET Detail
The changes of neutrophil gelatinase-associated lipocalin in plasma and its expression in adipose ti... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Neutrophil gelatinase-associated lipocalin (NGAL) and matrix metalloproteinase-9 (MMP-9) prognostic ... DisGeNET Detail
NA DisGeNET Detail
In this study, we observed that the expression levels of Lcn2 were significantly elevated in a rat P... DisGeNET Detail
NA DisGeNET Detail
Overexpression of LCN2 in ESCC cells accelerated cell migration and invasion in vitro, and promoted ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
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We identified a PPI network module associated with liver fibrosis that includes known liver fibrosis... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
At the time of first sample collection in the ED, gene expression of Interleukin (IL)-10 and Neutrop... DisGeNET Detail
NA DisGeNET Detail
Functional analysis of the mRNA profile of neutrophil gelatinase‑associated lipocalin overexpression... DisGeNET Detail
Shortest path analyses in the protein-protein interaction network of NGAL (neutrophil gelatinase-ass... DisGeNET Detail
Lipocalin 2 promotes the migration and invasion of esophageal squamous cell carcinoma cells through ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The downregulation of LCN2 expression was blunted when vitamin D receptor (VDR) was knocked down, im... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Over-expression of lipocalin 2 promotes cell migration and invasion through activating ERK signaling... DisGeNET Detail
By sandwich ELISA, serum and urinary LCN2 levels were measured in 36 patients with hematologic malig... DisGeNET Detail
NA DisGeNET Detail
The inflammation-lipocalin 2 axis may contribute to the development of chronic kidney disease. DisGeNET Detail
NA DisGeNET Detail
Targeting delivery of lipocalin 2-engineered mesenchymal stem cells to colon cancer in order to inhi... DisGeNET Detail
Plasma NGAL may play a role in the development of insulin resistance in GDM, and the high levels of ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
It was recently reported that lipocalin 2 (Lcn2) is up-regulated in a wide array of malignant condit... DisGeNET Detail
Over-expression of lipocalin 2 promotes cell migration and invasion through activating ERK signaling... DisGeNET Detail
LCN-2 mRNA showed a near 50-fold increase in expression, accompanied by down-regulation of SLC22A17,... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
This synergistic approach--coupling the CXCR4 axis blockade with Lcn2 silencing--significantly reduc... DisGeNET Detail
Estrogen receptor (ER)α-regulated lipocalin 2 expression in adipose tissue links obesity with breast... DisGeNET Detail
LCN-2 mRNA showed a near 50-fold increase in expression, accompanied by down-regulation of SLC22A17,... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Targeting delivery of lipocalin 2-engineered mesenchymal stem cells to colon cancer in order to inhi... DisGeNET Detail
Because the expression of lipocalin-2 (LCN2) was highly enhanced by promoter hypomethylation in inor... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The degree of temporal changes of P25 and N35 in ULD was similar or even lower than that of healthy ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
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The inflammation-lipocalin 2 axis may contribute to the development of chronic kidney disease. DisGeNET Detail
While urinary NGAL was greater in CKD than control subjects, exosomal NGAL mRNA was unchanged. DisGeNET Detail
Albumin-creatinine ratio (ACR), 4 tubular injury biomarkers (interleukin 18 [IL-18], kidney injury m... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Sustained elevation of resistin, NGAL and IL-8 are associated with severe sepsis/septic shock in the... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
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In patients without AKI and bacterial infection, at 1 week after SCT, the median blood neutrophil co... DisGeNET Detail
NA DisGeNET Detail
In a human cohort of women with recurrent E. coli UTIs, urine LCN2 levels were associated with UTI e... DisGeNET Detail
NA DisGeNET Detail
Because the expression of lipocalin-2 (LCN2) was highly enhanced by promoter hypomethylation in inor... DisGeNET Detail
This synergistic approach--coupling the CXCR4 axis blockade with Lcn2 silencing--significantly reduc... DisGeNET Detail
Estrogen receptor (ER)α-regulated lipocalin 2 expression in adipose tissue links obesity with breast... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Targeting delivery of lipocalin 2-engineered mesenchymal stem cells to colon cancer in order to inhi... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
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Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
dbSNP
rs386626619 dbSNP
Genome
hg38
Position
chr9:128,149,071-128,153,453
Variant Type
snv
Genome browser