Polycystic Kidney, Autosomal Dominant

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Information
Disease name
Polycystic Kidney, Autosomal Dominant
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT00410007 Completed N/A The Effect of High and Low Sodium Intake on Urinary Aquaporin-2 in Autosomal Dominant Polycystic Kidney Disease October 2006 November 2011
NCT00413777 Completed Phase 2 Tolvaptan Open-label Pilot Efficacy, Tolerability, and Safety Study in Autosomal Dominant Polycystic Kidney Disease (ADPKD) December 2005 June 2010
NCT00426153 Completed Phase 2/Phase 3 Octreotide in Severe Polycystic Liver Disease January 2007 October 2008
NCT00456365 Completed Phase 3 Effect of Statin Therapy on Disease Progression in Autosomal Dominant Polycystic Kidney Disease (ADPKD) November 2006 October 2012
NCT00565097 Completed Phase 2/Phase 3 Lanreotide as Treatment of Polycystic Livers October 2007
NCT01114594 Completed Pilot Study of RNA as a Biomarker for Autosomal Dominant Polycystic Kidney Disease April 2010 April 2012
NCT01233869 Completed Phase 2 Bosutinib For Autosomal Dominant Polycystic Kidney Disease December 2010 August 2014
NCT01559363 Completed Phase 1/Phase 2 A Safety, Pharmacokinetic & Dose-Escalation Study of KD019 in Subjects With Autosomal Dominant Polycystic Kidney Disease October 11, 2012 February 8, 2019
NCT03803124 Completed Phase 3 Effect of Tolvaptan on Renal Plasma Flow (RPF) and Glomerular Filtration Rate (GFR) in ADPKD December 2015 December 15, 2017
NCT04023214 Completed The Role of Endothelial Dysfunction in Adult Polycystic Kidney Disease July 25, 2011 December 31, 2018
NCT04363554 Completed N/A The Kidneys Ability to Concentrate and Dilute Urine in Patients With Autosomal Dominant Polycystic Kidney Disease September 25, 2017 April 20, 2020
NCT04407481 Completed PErfusioN, OxyGen ConsUmptIon and ENergetics in ADPKD (PENGUIN) November 1, 2020 October 13, 2022
NCT04534985 Completed N/A Time Restricted Feeding in Autosomal Dominant Polycystic Kidney Disease February 9, 2021 March 31, 2023
NCT02021110 Completed Phase 2 Ursodeoxycholic Acid as Treatment for Polycystic Liver Disease December 2013 October 2015
NCT02251275 Completed Phase 3 Long Term Safety of Immediate-release Tolvaptan in Subjects With Autosomal Dominant Polycystic Kidney Disease October 17, 2014 November 9, 2018
NCT02494141 Completed Phase 4 Curcumin Therapy to Treat Vascular Dysfunction in Children and Young Adults With ADPKD November 12, 2015 February 1, 2021
NCT02656017 Completed Phase 2 Metformin as a Novel Therapy for Autosomal Dominant Polycystic Kidney Disease June 27, 2016 December 7, 2020
NCT02847624 Completed Post-Marketing Surveillance Study of Tolvaptan in Patients With ADPKD March 24, 2014 September 20, 2022
NCT02903511 Completed Phase 2 Feasibility Study of Metformin Therapy in ADPKD November 2016 August 17, 2020
NCT03342742 Completed N/A Daily Caloric Restriction and Intermittent Fasting in Overweight and Obese Adults With Autosomal Dominant Polycystic Kidney Disease June 4, 2018 October 13, 2020
NCT03687554 Completed Phase 1 Effect of Venglustat in Patients With Renal Impairment October 5, 2018 February 27, 2019
NCT05521191 Recruiting Phase 1 A Study of RGLS8429 in Patients With Autosomal Dominant Polycystic Kidney Disease October 6, 2022 June 2025
NCT05510115 Recruiting Phase 2 Feasibility of Study of Empagliflozin in Patients With Autosomal Dominant Polycystic Kidney Disease November 18, 2022 March 31, 2026
NCT01589705 Terminated The Relation Between Uric Acid Level and Endothelial Dysfunction in Patients With Polycystic Kidney Disease January 2012 April 2012
NCT03523728 Terminated Phase 2/Phase 3 A Medical Research Study Designed to Determine if Venglustat Can be a Future Treatment for ADPKD Patients October 4, 2018 August 3, 2021
NCT04310319 Unknown status N/A Wishing to Decrease Aquaresis in ADPKD Patients Treated With a V2Ra; the Effect of Regulating Protein and Salt September 7, 2020 October 2021
ICD10 preferred id (Insert disease from ICD10)
D0013920
ICD10 class code (Insert disease from ICD10)
Q61.2
MeSH unique ID (MeSH (Medical Subject Headings))
D016891