chr17:40553769:> Detail (hg38)
Information
Genome
Assembly | Position |
---|---|
hg19 | chr17:38,710,021-38,721,724 |
hg38 | chr17:40,553,769-40,565,472 |
HGVS
Type | Transcript | Protein |
---|---|---|
Summary
MGeND
Clinical significance | |
Variant entry | |
GWAS entry | |
Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
Clinical Significance | |
Review star | [No Data.] |
Show details |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score | Disease name | Description | Source | Pubmed | Links |
---|---|---|---|---|---|
0.006 | squamous cell carcinoma | NA | BeFree,LHGDN | Detail | |
<0.001 | Chlamydia Infections | NA | BeFree | Detail | |
<0.001 | Primary biliary cirrhosis | NA | BeFree | Detail | |
0.002 | Congenital chromosomal disease | NA | BeFree | Detail | |
<0.001 | colitis | Furthermore, adoptive transfer of ΔARE/CCR7(-/-) effector CD4(+) into lymphopeni... | BeFree | 25637591 | Detail |
<0.001 | ulcerative colitis | NA | BeFree | Detail | |
0.003 | Colonic Neoplasms | NA | LHGDN | Detail | |
<0.001 | colorectal carcinoma | NA | BeFree | Detail | |
<0.001 | common variable immunodeficiency | NA | BeFree | Detail | |
<0.001 | Coronary Arteriosclerosis | NA | BeFree | Detail | |
<0.001 | Coronary heart disease | NA | BeFree | Detail | |
<0.001 | Crohn Disease | Chemokine receptor CCR7 regulates the intestinal TH1/TH17/Treg balance during Cr... | BeFree | 25637591 | Detail |
0.003 | Cytomegalovirus Infections | NA | LHGDN | Detail | |
0.002 | Diabetes Mellitus, Insulin-Dependent | NA | GAD | Detail | |
<0.001 | Experimental Autoimmune Encephalomyelitis | NA | BeFree | Detail | |
<0.001 | Ependymoma | NA | BeFree | Detail | |
<0.001 | Fanconi anemia | NA | BeFree | Detail | |
<0.001 | Glioma | NA | BeFree | Detail | |
<0.001 | Graft-vs-Host Disease | NA | BeFree | Detail | |
<0.001 | chronic granulomatous disease | NA | BeFree | Detail | |
<0.001 | Heart failure | NA | BeFree | Detail | |
<0.001 | congestive heart failure | NA | BeFree | Detail | |
<0.001 | Hepatosplenomegaly | NA | BeFree | Detail | |
<0.001 | Herpes Simplex Infections | NA | BeFree | Detail | |
0.003 | Histiocytosis, Langerhans-Cell | NA | LHGDN | Detail | |
0.004 | HIV Infections | Numbers of naive CCR7(+) CD4(+) T cells were reduced (p = 0.01) in HIV-1-exposed... | BeFree,GAD | 25341640 | Detail |
<0.001 | Hodgkin Disease | NA | BeFree | Detail | |
<0.001 | Hyperlipidemia | In mouse models of atherosclerosis, normalization of hyperlipidemia promotes mac... | BeFree | 25825525 | Detail |
<0.001 | pulmonary hypertension | NA | BeFree | Detail | |
<0.001 | ileitis | Chemokine receptor CCR7 regulates the intestinal TH1/TH17/Treg balance during Cr... | BeFree | 25637591 | Detail |
0.010 | chronic lymphocytic leukemia | After adjustment for multiple testing, we found a strong association between CLL... | BeFree | 19074885 | Detail |
0.003 | Inflammation | NA | LHGDN | Detail | |
0.014 | leukemia | High EVI1 expression was detected mainly in myelomonocytic-lineage (designated a... | BeFree | 25567132 | Detail |
0.014 | leukemia | EVI1 protein expression revealed distinct normal-tissue and leukemia-associated ... | BeFree | 25936528 | Detail |
0.010 | chronic lymphocytic leukemia | Preclinical activity of anti-CCR7 immunotherapy in patients with high-risk chron... | BeFree,GAD,LHGDN | 25724841 | Detail |
0.010 | chronic lymphocytic leukemia | The regulatory interaction of EVI1 with the TCL1A oncogene impacts cell survival... | BeFree,GAD,LHGDN | 25936528 | Detail |
0.010 | chronic lymphocytic leukemia | We show that recycling accounts, to a major extent, for the high levels of surfa... | BeFree,GAD,LHGDN | 26282174 | Detail |
<0.001 | Acute lymphocytic leukemia | NA | BeFree | Detail | |
<0.001 | acute monocytic leukemia | NA | BeFree | Detail | |
0.017 | Leukemia, Myelocytic, Acute | EVI1-rearranged acute myeloid leukemias are characterized by distinct molecular ... | BeFree | 25331116 | Detail |
0.017 | Leukemia, Myelocytic, Acute | CADM1 up-regulation was abolished by ectopic expression of EVI1, and EVI1 expres... | BeFree | 25491945 | Detail |
0.017 | Leukemia, Myelocytic, Acute | From gene expression profiling data of 130 Japanese pediatric acute myeloid leuk... | BeFree | 25567132 | Detail |
0.017 | Leukemia, Myelocytic, Acute | MS4A3 mRNA levels were also negatively correlated with those of EVI1 in several ... | BeFree | 25886616 | Detail |
0.007 | myeloid leukemia | The transcription factor Ecotropic Virus Integration site 1 (EVI1) regulates cel... | BeFree | 25886616 | Detail |
0.007 | myeloid leukemia | EVI1 (ecotropic viral integration site 1) is one of the most aggressive oncogene... | BeFree | 25959919 | Detail |
0.005 | Myeloid Leukemia, Chronic | NA | BeFree | Detail | |
<0.001 | Leukemia, Myeloid, Chronic-Phase | NA | BeFree | Detail | |
0.001 | acute promyelocytic leukemia | NA | BeFree | Detail | |
<0.001 | Leukemia, T-Cell | NA | BeFree | Detail | |
0.120 | Adult T-Cell Lymphoma/Leukemia | NA | BeFree,CTD_human | Detail | |
0.003 | Lung Neoplasms | NA | LHGDN | Detail | |
0.004 | Lupus Erythematosus, Systemic | NA | BeFree,LHGDN | Detail | |
0.003 | Lyme disease | NA | LHGDN | Detail | |
<0.001 | Lymphatic Metastasis | Chemokine (C-C motif) receptor 7 (CCR7) is involved in lymph-node homing of naiv... | BeFree | 24915301 | Detail |
0.001 | lymphoma | NA | BeFree | Detail | |
0.003 | Lymphoma, Non-Hodgkin | NA | LHGDN | Detail | |
<0.001 | malaria | NA | BeFree | Detail | |
0.001 | Malignant neoplasm of stomach | CCR7 pathway induces epithelial-mesenchymal transition through up-regulation of ... | BeFree | 25572817 | Detail |
0.009 | melanoma | NA | BeFree,LHGDN | Detail | |
<0.001 | Monoclonal Gammopathy of Undetermined Significance | NA | BeFree | Detail | |
0.002 | Monosomy | NA | BeFree | Detail | |
<0.001 | multiple myeloma | NA | BeFree | Detail | |
0.003 | multiple sclerosis | NA | LHGDN | Detail | |
0.002 | Myelodysplasia | NA | BeFree | Detail | |
<0.001 | Myelomonocytic leukemia | NA | BeFree | Detail | |
<0.001 | Myeloproliferative disease | NA | BeFree | Detail | |
0.003 | myositis | NA | LHGDN | Detail | |
0.024 | Neoplasm Metastasis | We presumed that CCL21/CCR7 axis activates EMT process to induce cancer cell inv... | BeFree,LHGDN | 25142946 | Detail |
0.024 | Neoplasm Metastasis | Thus, this study suggested that the epithelial ovarian cancer invasion and metas... | BeFree,LHGDN | 25168373 | Detail |
0.024 | Neoplasm Metastasis | Together, our findings suggest that CCRL1 impairs chemotactic events associated ... | BeFree,LHGDN | 25255875 | Detail |
0.024 | Neoplasm Metastasis | Positive lymph-node breast cancer patients – activation of NF-κB in tumor-associ... | BeFree,LHGDN | 25327843 | Detail |
0.024 | Neoplasm Metastasis | In conclusion, JAk2/STAT3 plays a key role in CCR7 regulating SCCHN metastasis. | BeFree,LHGDN | 25405202 | Detail |
0.024 | Neoplasm Metastasis | Targeting of TGF-β-activated protein kinase 1 inhibits chemokine (C-C motif) rec... | BeFree,LHGDN | 25557171 | Detail |
0.024 | Neoplasm Metastasis | The increased expression of CCR7 was closely associated with the increased Snail... | BeFree,LHGDN | 25572817 | Detail |
0.024 | Neoplasm Metastasis | CC-chemokine receptor 7 is overexpressed and correlates with growth and metastas... | BeFree,LHGDN | 25682287 | Detail |
<0.001 | obesity | NA | BeFree | Detail | |
0.001 | ovarian carcinoma | NA | BeFree | Detail | |
0.003 | Pancreatic Neoplasm | NA | LHGDN | Detail | |
<0.001 | pancytopenia | NA | BeFree | Detail | |
<0.001 | polycythemia vera | NA | BeFree | Detail | |
<0.001 | Precancerous Conditions | NA | BeFree | Detail | |
0.003 | Preleukemia | NA | BeFree | Detail | |
<0.001 | psoriasis | NA | BeFree | Detail | |
<0.001 | systemic scleroderma | NA | BeFree | Detail | |
<0.001 | Sezary syndrome | NA | BeFree | Detail | |
0.120 | status epilepticus | NA | CTD_human | Detail | |
0.003 | Stomach Neoplasms | NA | BeFree,LHGDN | Detail | |
<0.001 | thymoma | NA | BeFree | Detail | |
0.003 | Thyroid Neoplasm | NA | LHGDN | Detail | |
<0.001 | Lymphoma, T-Cell, Cutaneous | NA | BeFree | Detail | |
<0.001 | severe combined immunodeficiency | NA | BeFree | Detail | |
0.003 | polymyositis | NA | BeFree,LHGDN | Detail | |
0.001 | acute leukemia | NA | BeFree | Detail | |
<0.001 | Hamman-Rich syndrome | NA | BeFree | Detail | |
<0.001 | benign neoplasm | NA | BeFree | Detail | |
<0.001 | Adenocarcinoma of lung (disorder) | NA | BeFree | Detail | |
<0.001 | Idiopathic pulmonary hypertension | NA | BeFree | Detail | |
<0.001 | Secondary malignant neoplasm of lung | NA | BeFree | Detail | |
<0.001 | Chronic obstructive asthma (with obstructive pulmonary disease) | The CXCR4/CXCL12 axis contributes to chemotaxis of fibrocytes in patients in the... | BeFree | 25441632 | Detail |
<0.001 | Malnutrition | NA | BeFree | Detail | |
<0.001 | Adult Acute Myeloblastic Leukemia | NA | BeFree | Detail | |
<0.001 | pediatric acute myeloblastic leukemia | High expression of EVI1 and MEL1 is a compelling poor prognostic marker of pedia... | BeFree | 25567132 | Detail |
<0.001 | uveal melanoma | NA | BeFree | Detail | |
<0.001 | Lung infiltration | NA | BeFree | Detail | |
<0.001 | pancreatic carcinoma | NA | BeFree | Detail | |
<0.001 | Papillary thyroid carcinoma | NA | BeFree | Detail | |
<0.001 | Malignant neoplasm of lung | NA | BeFree | Detail | |
<0.001 | Neoplasm, Residual | NA | BeFree | Detail | |
<0.001 | Congenital thrombocytopenia | NA | BeFree | Detail | |
<0.001 | Carcinoma breast stage IV | NA | BeFree | Detail | |
<0.001 | inflammatory breast carcinoma | NA | BeFree | Detail | |
<0.001 | gastric adenocarcinoma | NA | BeFree | Detail | |
<0.001 | Philadelphia chromosome positive chronic myelogenous leukemia | NA | BeFree | Detail | |
<0.001 | Squamous cell carcinoma of esophagus | NA | BeFree | Detail | |
<0.001 | Solid tumour | NA | BeFree | Detail | |
<0.001 | Acute Undifferentiated Leukemia | NA | BeFree | Detail | |
<0.001 | secondary acute myeloid leukemia | NA | BeFree | Detail | |
<0.001 | Squamous cell carcinoma, metastatic | CCR7 regulates cell migration and invasion through JAK2/STAT3 in metastatic squa... | BeFree | 25405202 | Detail |
<0.001 | Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse | NA | BeFree | Detail | |
<0.001 | intestinal cancer | NA | BeFree | Detail | |
<0.001 | Malignant neoplasm of pancreas | NA | BeFree | Detail | |
<0.001 | juvenile myelomonocytic leukemia | NA | BeFree | Detail | |
<0.001 | Malignant neoplasm of prostate | The effect of CCL19/CCR7 on the proliferation and migration of cell in prostate ... | BeFree | 25256673 | Detail |
<0.001 | Malignant neoplasm of prostate | CC-chemokine receptor 7 is overexpressed and correlates with growth and metastas... | BeFree | 25682287 | Detail |
0.002 | Hematologic Neoplasms | NA | BeFree | Detail | |
<0.001 | Chromosome 8, trisomy | NA | BeFree | Detail | |
<0.001 | endometrial carcinoma | NA | BeFree | Detail | |
<0.001 | Secondary malignant neoplasm of liver | NA | BeFree | Detail | |
<0.001 | Benign neurologic neoplasms | NA | BeFree | Detail | |
<0.001 | Hepatitis C, Chronic | NA | BeFree | Detail | |
<0.001 | Thyroid carcinoma | NA | BeFree | Detail | |
<0.001 | Malignant glioma | IFN-DC of patients with malignant gliomas were characterized by low chemotaxis i... | BeFree | 25894778 | Detail |
<0.001 | Tonsillar Carcinoma | NA | BeFree | Detail | |
0.001 | Carcinogenesis | NA | BeFree | Detail | |
0.005 | Leukemogenesis | NA | BeFree | Detail | |
<0.001 | prostate carcinoma | The effect of CCL19/CCR7 on the proliferation and migration of cell in prostate ... | BeFree | 25256673 | Detail |
<0.001 | prostate carcinoma | CC-chemokine receptor 7 is overexpressed and correlates with growth and metastas... | BeFree | 25682287 | Detail |
<0.001 | Epithelial ovarian cancer | The essential roles of CCR7 in epithelial-to-mesenchymal transition induced by h... | BeFree | 25168373 | Detail |
0.004 | breast carcinoma | In addition, inhibition of aberrant sialylation of CCR7 suppresses proliferation... | BeFree | 24915301 | Detail |
0.004 | breast carcinoma | CCL21/CCR7 axis activating chemotaxis accompanied with epithelial-mesenchymal tr... | BeFree | 25142946 | Detail |
0.004 | breast carcinoma | Our findings show that the molecular cues secreted by TALs alone or in combinati... | BeFree | 25327843 | Detail |
0.004 | breast carcinoma | Targeting of TGF-β-activated protein kinase 1 inhibits chemokine (C-C motif) rec... | BeFree | 25557171 | Detail |
0.004 | breast carcinoma | The role of CCL21/CCR7 chemokine axis in breast cancer-induced lymphangiogenesis... | BeFree | 25744065 | Detail |
<0.001 | Carcinoma of lung | NA | BeFree | Detail | |
0.005 | Secondary malignant neoplasm of lymph node | By immunohistolochemistry, high expressions of CCR7, Slug and N-cadherin were se... | BeFree | 25142946 | Detail |
0.005 | Secondary malignant neoplasm of lymph node | Our data showed CCR7 expression was observed in 22 cases of tissues and closely ... | BeFree | 25168373 | Detail |
0.005 | Secondary malignant neoplasm of lymph node | Our findings show that the molecular cues secreted by TALs alone or in combinati... | BeFree | 25327843 | Detail |
0.005 | Secondary malignant neoplasm of lymph node | The immunohistochemistry results also showed that the phosphorylation of STAT3 w... | BeFree | 25405202 | Detail |
<0.001 | colon carcinoma | NA | BeFree | Detail | |
0.002 | stomach carcinoma | CCR7 pathway induces epithelial-mesenchymal transition through up-regulation of ... | BeFree | 25572817 | Detail |
<0.001 | gastritis h pylori | NA | BeFree | Detail | |
<0.001 | Malignant neoplasm tonsil | NA | BeFree | Detail | |
<0.001 | Pancreatic carcinoma resectable | NA | BeFree | Detail | |
<0.001 | Post MI | NA | BeFree | Detail | |
<0.001 | Acute GVH disease | NA | BeFree | Detail | |
0.001 | Malignant neoplasm of ovary | NA | BeFree | Detail | |
0.001 | Squamous cell carcinoma of the head and neck | In conclusion, JAk2/STAT3 plays a key role in CCR7 regulating SCCHN metastasis. | BeFree | 25405202 | Detail |
<0.001 | Lymphocytic infiltration | NA | BeFree | Detail | |
<0.001 | Chronic inflammatory disorder | NA | BeFree | Detail | |
<0.001 | Precursor B-cell lymphoblastic leukemia | NA | BeFree | Detail | |
<0.001 | Acute Myeloid Leukemia Arising from Previous Myelodysplastic Syndrome | We report here a multicentre retrospective study of 157 patients treated with AZ... | BeFree | 26113240 | Detail |
<0.001 | Undifferentiated leukemia | NA | BeFree | Detail | |
0.009 | Mammary Neoplasms | However, the expression and association of activated TAK1 and CCR7 in breast tum... | BeFree,LHGDN | 25557171 | Detail |
<0.001 | Xenograft Model | Experimental re-expression of MS4A3 in an EVI1 overexpressing cell line countera... | BeFree | 25886616 | Detail |
<0.001 | colorectal cancer | NA | BeFree | Detail | |
0.080 | Sjogren's syndrome | NA | MGD | Detail | |
<0.001 | Benign Prostatic Hyperplasia | The positive rate of CCL19 staining was 87.04 % (94/108) in 108 cases of prostat... | BeFree | 25256673 | Detail |
<0.001 | Benign Prostatic Hyperplasia | The positive rate of CCR7 staining was 88.33 % (53/60) in the PCa group and 16.6... | BeFree | 25682287 | Detail |
<0.001 | Non-Neoplastic Disorder | NA | BeFree | Detail | |
<0.001 | Idiopathic Pulmonary Fibrosis | NA | BeFree | Detail | |
<0.001 | coronary artery disease | NA | BeFree | Detail | |
<0.001 | Myocardial Failure | NA | BeFree | Detail | |
<0.001 | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | NA | BeFree | Detail | |
0.001 | Precursor Cell Lymphoblastic Leukemia Lymphoma | NA | BeFree | Detail | |
0.004 | liver carcinoma | The expression of CCL19 and its receptor (CCR7) in different HCC cell lines were... | BeFree,LHGDN | 25225162 | Detail |
0.004 | liver carcinoma | CC chemokine receptor-like 1 functions as a tumour suppressor by impairing CCR7-... | BeFree,LHGDN | 25255875 | Detail |
0.004 | liver carcinoma | EVI1, a target gene for amplification at 3q26, antagonizes transforming growth f... | BeFree,LHGDN | 25959919 | Detail |
<0.001 | Promyelocytic leukemia | NA | BeFree | Detail | |
<0.001 | Nasopharyngeal carcinoma | NA | BeFree | Detail | |
<0.001 | myeloid neoplasm | We therefore sought to identify EVI1 target genes that may play a role in chemot... | BeFree | 25491945 | Detail |
<0.001 | Pulmonary arterial hypertension | NA | BeFree | Detail | |
0.001 | myelodysplastic syndrome | NA | BeFree | Detail | |
<0.001 | FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) | NA | BeFree | Detail | |
0.003 | Juvenile arthritis | NA | BeFree,LHGDN | Detail | |
0.003 | Infection | NA | LHGDN | Detail | |
<0.001 | juvenile rheumatoid arthritis | NA | BeFree | Detail | |
<0.001 | Pulmonary hypertension, primary, 1, with hereditary hemorrhagic telangiectasia | NA | BeFree | Detail | |
0.003 | adenocarcinoma | Here, we addressed the roles of CCR7 in epithelial ovarian carcinoma tissues and... | BeFree,LHGDN | 25168373 | Detail |
<0.001 | anemia | NA | BeFree | Detail | |
<0.001 | aplastic anemia | NA | BeFree | Detail | |
<0.001 | Refractory anaemia with excess blasts | NA | BeFree | Detail | |
<0.001 | arteriosclerosis | NA | BeFree | Detail | |
<0.001 | asthma | CXCL12/CXCR4 and CCL19/CCR7 enhanced fibrocyte transmigration in the Asthma AE g... | BeFree | 25441632 | Detail |
<0.001 | atherosclerosis | NA | BeFree | Detail | |
<0.001 | Autoimmune Diseases | NA | BeFree | Detail | |
<0.001 | Behcet Syndrome | NA | BeFree | Detail | |
0.003 | Blast Phase | NA | BeFree | Detail | |
0.006 | Malignant neoplasm of breast | In addition, inhibition of aberrant sialylation of CCR7 suppresses proliferation... | BeFree,GAD | 24915301 | Detail |
0.006 | Malignant neoplasm of breast | CCL21/CCR7 axis activating chemotaxis accompanied with epithelial-mesenchymal tr... | BeFree,GAD | 25142946 | Detail |
0.006 | Malignant neoplasm of breast | Our findings show that the molecular cues secreted by TALs alone or in combinati... | BeFree,GAD | 25327843 | Detail |
0.006 | Malignant neoplasm of breast | Targeting of TGF-β-activated protein kinase 1 inhibits chemokine (C-C motif) rec... | BeFree,GAD | 25557171 | Detail |
0.006 | Malignant neoplasm of breast | The role of CCL21/CCR7 chemokine axis in breast cancer-induced lymphangiogenesis... | BeFree,GAD | 25744065 | Detail |
<0.001 | Malignant tumor of colon | NA | BeFree | Detail | |
0.001 | Non-small cell lung carcinoma | NA | BeFree | Detail |
Annotation
Annotations
Descrption | Source | Links |
---|---|---|
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Furthermore, adoptive transfer of ΔARE/CCR7(-/-) effector CD4(+) into lymphopenic hosts resulted in ... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Chemokine receptor CCR7 regulates the intestinal TH1/TH17/Treg balance during Crohn's-like murine il... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Numbers of naive CCR7(+) CD4(+) T cells were reduced (p = 0.01) in HIV-1-exposed infants. | DisGeNET | Detail |
NA | DisGeNET | Detail |
In mouse models of atherosclerosis, normalization of hyperlipidemia promotes macrophage emigration a... | DisGeNET | Detail |
NA | DisGeNET | Detail |
Chemokine receptor CCR7 regulates the intestinal TH1/TH17/Treg balance during Crohn's-like murine il... | DisGeNET | Detail |
After adjustment for multiple testing, we found a strong association between CLL risk and six geneti... | DisGeNET | Detail |
NA | DisGeNET | Detail |
High EVI1 expression was detected mainly in myelomonocytic-lineage (designated as e-M4/M5 subtype) l... | DisGeNET | Detail |
EVI1 protein expression revealed distinct normal-tissue and leukemia-associated patterns of EVI1/TCL... | DisGeNET | Detail |
Preclinical activity of anti-CCR7 immunotherapy in patients with high-risk chronic lymphocytic leuke... | DisGeNET | Detail |
The regulatory interaction of EVI1 with the TCL1A oncogene impacts cell survival and clinical outcom... | DisGeNET | Detail |
We show that recycling accounts, to a major extent, for the high levels of surface CXCR4/CCR7 on CLL... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
EVI1-rearranged acute myeloid leukemias are characterized by distinct molecular alterations. | DisGeNET | Detail |
CADM1 up-regulation was abolished by ectopic expression of EVI1, and EVI1 expression correlated with... | DisGeNET | Detail |
From gene expression profiling data of 130 Japanese pediatric acute myeloid leukemia (AML) patients,... | DisGeNET | Detail |
MS4A3 mRNA levels were also negatively correlated with those of EVI1 in several published AML data s... | DisGeNET | Detail |
The transcription factor Ecotropic Virus Integration site 1 (EVI1) regulates cellular proliferation,... | DisGeNET | Detail |
EVI1 (ecotropic viral integration site 1) is one of the most aggressive oncogenes associated with my... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Chemokine (C-C motif) receptor 7 (CCR7) is involved in lymph-node homing of naive and regulatory T c... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
CCR7 pathway induces epithelial-mesenchymal transition through up-regulation of Snail signaling in g... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
We presumed that CCL21/CCR7 axis activates EMT process to induce cancer cell invasion and metastasis... | DisGeNET | Detail |
Thus, this study suggested that the epithelial ovarian cancer invasion and metastasis can be inhibit... | DisGeNET | Detail |
Together, our findings suggest that CCRL1 impairs chemotactic events associated with CCR7 in the pro... | DisGeNET | Detail |
Positive lymph-node breast cancer patients – activation of NF-κB in tumor-associated leukocytes stim... | DisGeNET | Detail |
In conclusion, JAk2/STAT3 plays a key role in CCR7 regulating SCCHN metastasis. | DisGeNET | Detail |
Targeting of TGF-β-activated protein kinase 1 inhibits chemokine (C-C motif) receptor 7 expression, ... | DisGeNET | Detail |
The increased expression of CCR7 was closely associated with the increased Snail expression, which b... | DisGeNET | Detail |
CC-chemokine receptor 7 is overexpressed and correlates with growth and metastasis in prostate cance... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
The CXCR4/CXCL12 axis contributes to chemotaxis of fibrocytes in patients in the Asthma AE group, wh... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
High expression of EVI1 and MEL1 is a compelling poor prognostic marker of pediatric AML. | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
CCR7 regulates cell migration and invasion through JAK2/STAT3 in metastatic squamous cell carcinoma ... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
The effect of CCL19/CCR7 on the proliferation and migration of cell in prostate cancer. | DisGeNET | Detail |
CC-chemokine receptor 7 is overexpressed and correlates with growth and metastasis in prostate cance... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
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IFN-DC of patients with malignant gliomas were characterized by low chemotaxis in response to CCL19 ... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
The effect of CCL19/CCR7 on the proliferation and migration of cell in prostate cancer. | DisGeNET | Detail |
CC-chemokine receptor 7 is overexpressed and correlates with growth and metastasis in prostate cance... | DisGeNET | Detail |
The essential roles of CCR7 in epithelial-to-mesenchymal transition induced by hypoxia in epithelial... | DisGeNET | Detail |
In addition, inhibition of aberrant sialylation of CCR7 suppresses proliferation and invasion and tr... | DisGeNET | Detail |
CCL21/CCR7 axis activating chemotaxis accompanied with epithelial-mesenchymal transition in human br... | DisGeNET | Detail |
Our findings show that the molecular cues secreted by TALs alone or in combination with CCR7 may eme... | DisGeNET | Detail |
Targeting of TGF-β-activated protein kinase 1 inhibits chemokine (C-C motif) receptor 7 expression, ... | DisGeNET | Detail |
The role of CCL21/CCR7 chemokine axis in breast cancer-induced lymphangiogenesis. | DisGeNET | Detail |
NA | DisGeNET | Detail |
By immunohistolochemistry, high expressions of CCR7, Slug and N-cadherin were seen in 60, 65, and 76... | DisGeNET | Detail |
Our data showed CCR7 expression was observed in 22 cases of tissues and closely associated with lymp... | DisGeNET | Detail |
Our findings show that the molecular cues secreted by TALs alone or in combination with CCR7 may eme... | DisGeNET | Detail |
The immunohistochemistry results also showed that the phosphorylation of STAT3 was correlated with C... | DisGeNET | Detail |
NA | DisGeNET | Detail |
CCR7 pathway induces epithelial-mesenchymal transition through up-regulation of Snail signaling in g... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
In conclusion, JAk2/STAT3 plays a key role in CCR7 regulating SCCHN metastasis. | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
We report here a multicentre retrospective study of 157 patients treated with AZA for AML/MDS with c... | DisGeNET | Detail |
NA | DisGeNET | Detail |
However, the expression and association of activated TAK1 and CCR7 in breast tumor tissues is unknow... | DisGeNET | Detail |
Experimental re-expression of MS4A3 in an EVI1 overexpressing cell line counteracted the tumor promo... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
The positive rate of CCL19 staining was 87.04 % (94/108) in 108 cases of prostatic carcinoma and 16.... | DisGeNET | Detail |
The positive rate of CCR7 staining was 88.33 % (53/60) in the PCa group and 16.67 % (10/60) in cases... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
The expression of CCL19 and its receptor (CCR7) in different HCC cell lines were screened by Western... | DisGeNET | Detail |
CC chemokine receptor-like 1 functions as a tumour suppressor by impairing CCR7-related chemotaxis i... | DisGeNET | Detail |
EVI1, a target gene for amplification at 3q26, antagonizes transforming growth factor-β-mediated gro... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
We therefore sought to identify EVI1 target genes that may play a role in chemotherapy resistance us... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Here, we addressed the roles of CCR7 in epithelial ovarian carcinoma tissues and hypoxia-induced ser... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
CXCL12/CXCR4 and CCL19/CCR7 enhanced fibrocyte transmigration in the Asthma AE group and in patients... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
In addition, inhibition of aberrant sialylation of CCR7 suppresses proliferation and invasion and tr... | DisGeNET | Detail |
CCL21/CCR7 axis activating chemotaxis accompanied with epithelial-mesenchymal transition in human br... | DisGeNET | Detail |
Our findings show that the molecular cues secreted by TALs alone or in combination with CCR7 may eme... | DisGeNET | Detail |
Targeting of TGF-β-activated protein kinase 1 inhibits chemokine (C-C motif) receptor 7 expression, ... | DisGeNET | Detail |
The role of CCL21/CCR7 chemokine axis in breast cancer-induced lymphangiogenesis. | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Overlapped Transcript Coordinates
Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
---|
Overlapped Transcript
Gene | Transcript ID | Chromosome | Start | Stop | Links |
---|
- Gene
- -
- dbSNP
- rs2266690 dbSNP
- Genome
- hg38
- Position
- chr17:40,553,769-40,565,472
- Variant Type
- snv
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