Annotation Detail
Information
- Associated Genes
- CCR7
- Associated Variants
-
CCR7 MUTATION
CCR7 MUTATION - Associated Disease
- Hyperlipidemia
- Source Database
- DisGeNET
- Description
- In mouse models of atherosclerosis, normalization of hyperlipidemia promotes macrophage emigration and regression of atherosclerotic plaques in part by liver X receptor (LXR)-mediated induction of the chemokine receptor CCR7.
- Pubmed
- 25825525
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 1
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs