Annotation Detail

Information
Associated Genes
CCR7
Associated Variants
CCR7 MUTATION
CCR7 MUTATION
Associated Disease
myeloid leukemia
Source Database
DisGeNET
Description
The transcription factor Ecotropic Virus Integration site 1 (EVI1) regulates cellular proliferation, differentiation, and apoptosis, and its overexpression contributes to an aggressive course of disease in myeloid leukemias and other malignancies.
Pubmed
25886616
Section of the abstract supporting the evidence
BACKGROUND
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00705748867408789
Drugs