Annotation Detail

Information
Associated Genes
CCR7
Associated Variants
CCR7 MUTATION
CCR7 MUTATION
Associated Disease
Chronic obstructive asthma (with obstructive pulmonary disease)
Source Database
DisGeNET
Description
The CXCR4/CXCL12 axis contributes to chemotaxis of fibrocytes in patients in the Asthma AE group, whereas the CCR7/CCL19 axis plays an important role in patients with COA.
Pubmed
25441632
Section of the abstract supporting the evidence
CONCLUSION
Number of the section of the abstract supporting the evidence
5
Number of the sentence supporting the evidence
12
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs