chr17:76352859:> Detail (hg19)
Information
Genome
Assembly | Position |
---|---|
hg19 | chr17:76,352,859-76,356,158 |
hg38 | chr17:78,356,778-78,360,077 |
HGVS
Type | Transcript | Protein |
---|---|---|
Summary
MGeND
Clinical significance | |
Variant entry | |
GWAS entry | |
Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
Clinical Significance | |
Review star | [No Data.] |
Show details |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score | Disease name | Description | Source | Pubmed | Links |
---|---|---|---|---|---|
0.003 | squamous cell carcinoma | NA | LHGDN | Detail | |
<0.001 | CNS disorder | NA | BeFree | Detail | |
<0.001 | Malignant tumor of cervix | NA | BeFree | Detail | |
<0.001 | colitis | NA | BeFree | Detail | |
0.004 | ulcerative colitis | FOS and SOCS3 were identified as candidate genes for CD and other three genes HE... | BeFree,LHGDN | 25182475 | Detail |
0.004 | ulcerative colitis | Prevention of SOCS3 expression or enhancement of IL-22/STAT3 signaling in IEC se... | BeFree,LHGDN | 25545374 | Detail |
0.002 | colorectal carcinoma | NA | BeFree | Detail | |
0.003 | allergic conjunctivitis | NA | LHGDN | Detail | |
<0.001 | Crohn Disease | FOS and SOCS3 were identified as candidate genes for CD and other three genes HE... | BeFree | 25182475 | Detail |
0.001 | Dermatitis, Atopic | NA | BeFree | Detail | |
0.001 | Diabetes | MicroRNA-185 targets SOCS3 to inhibit beta-cell dysfunction in diabetes. | BeFree | 25658748 | Detail |
0.001 | diabetes mellitus | MicroRNA-185 targets SOCS3 to inhibit beta-cell dysfunction in diabetes. | BeFree | 25658748 | Detail |
0.080 | Diabetes Mellitus, Experimental | NA | RGD | Detail | |
0.005 | Diabetes Mellitus, Insulin-Dependent | NA | BeFree,GAD | Detail | |
0.001 | Diabetes Mellitus, Non-Insulin-Dependent | NA | BeFree | Detail | |
0.001 | Eczema | NA | BeFree | Detail | |
<0.001 | Filarial Elephantiases | NA | BeFree | Detail | |
0.120 | Endometrial Neoplasms | NA | CTD_human | Detail | |
0.080 | Fibrosis | NA | RGD | Detail | |
0.003 | glioblastoma | NA | BeFree,LHGDN | Detail | |
<0.001 | Glioma | NA | BeFree | Detail | |
0.001 | hepatitis | NA | BeFree | Detail | |
0.001 | hepatitis A | NA | BeFree | Detail | |
<0.001 | hepatitis B | We found that elevated expression of suppressor of cytokine signaling 3 (SOCS3) ... | BeFree | 25766860 | Detail |
<0.001 | Hepatitis, Chronic | NA | BeFree | Detail | |
0.004 | hepatitis C | Short communication: serum-based assay accurately detects single nucleotide poly... | BeFree,LHGDN | 24946792 | Detail |
0.001 | HIV Infections | Short communication: serum-based assay accurately detects single nucleotide poly... | BeFree | 24946792 | Detail |
<0.001 | hyperglycemia | NA | BeFree | Detail | |
<0.001 | hypoglycemia | NA | BeFree | Detail | |
<0.001 | Hypomenorrhea | NA | BeFree | Detail | |
0.003 | Immune System Diseases | NA | BeFree,LHGDN | Detail | |
0.003 | Inflammation | NA | LHGDN | Detail | |
<0.001 | Inflammatory Bowel Diseases | NA | BeFree | Detail | |
<0.001 | influenza | Obese influenza-free volunteers showed an increased basal expression of SOCS3, b... | BeFree | 24182768 | Detail |
<0.001 | Kidney Diseases | NA | BeFree | Detail | |
<0.001 | leiomyosarcoma | NA | BeFree | Detail | |
<0.001 | leukemia | NA | BeFree | Detail | |
<0.001 | Leukemia, Myelocytic, Acute | NA | BeFree | Detail | |
0.004 | Myeloid Leukemia, Chronic | Thus SOCS-3 provides a suitable candidate for mechanisms underlying the developm... | BeFree,LHGDN | 24969884 | Detail |
<0.001 | leukopenia | NA | BeFree | Detail | |
<0.001 | liver cirrhosis | NA | BeFree | Detail | |
0.120 | Liver diseases | NA | CTD_human | Detail | |
<0.001 | Liver neoplasms | NA | BeFree | Detail | |
<0.001 | Chronic Obstructive Airway Disease | Our findings suggest that IL6 and SOCS3 play important roles in COPD and have th... | BeFree | 25535123 | Detail |
0.005 | Lung Neoplasms | NA | LHGDN | Detail | |
<0.001 | Lupus Erythematosus, Systemic | NA | BeFree | Detail | |
0.003 | lymphadenitis | NA | LHGDN | Detail | |
<0.001 | Lymphoma, Follicular | NA | BeFree | Detail | |
0.003 | Lymphoma, Non-Hodgkin | NA | BeFree,GAD | Detail | |
<0.001 | Malignant neoplasm of stomach | Low expression of SOCS-1 and SOCS-3 is a poor prognostic indicator for gastric c... | BeFree | 25261987 | Detail |
0.004 | melanoma | NA | BeFree,LHGDN | Detail | |
<0.001 | Mesothelioma | NA | BeFree | Detail | |
<0.001 | mitral valve stenosis | NA | BeFree | Detail | |
<0.001 | multiple myeloma | NA | BeFree | Detail | |
<0.001 | multiple sclerosis | NA | BeFree | Detail | |
<0.001 | mycosis fungoides | NA | BeFree | Detail | |
<0.001 | myelofibrosis | NA | BeFree | Detail | |
0.001 | Myeloproliferative disease | NA | BeFree | Detail | |
<0.001 | Nasal Polyps | NA | BeFree | Detail | |
0.004 | Neoplasm Metastasis | In transformed cells, enforced expression of SOCS3 or interfering with IL6 pathw... | BeFree,LHGDN | 24531711 | Detail |
<0.001 | neuroblastoma | NA | BeFree | Detail | |
<0.001 | neutropenia | NA | BeFree | Detail | |
0.088 | obesity | During influenza infection, SOCS1 and SOCS3 expression was higher in the lean in... | BeFree,GAD,RGD | 24182768 | Detail |
0.088 | obesity | In chronic hepatitis C virus infection (CHC), expression of suppressor of cytoki... | BeFree,GAD,RGD | 24461080 | Detail |
<0.001 | Degenerative polyarthritis | NA | BeFree | Detail | |
<0.001 | Osteoarthritis of hip | Gene EP of TNF, IL-6, IL-8, CHIT1, BMP4, CCL3, CCL18, MMP9, RANKL, OPG, DC-STAMP... | BeFree | 25151085 | Detail |
<0.001 | osteosarcoma | NA | BeFree | Detail | |
<0.001 | peritonitis | NA | BeFree | Detail | |
<0.001 | pneumonia | NA | BeFree | Detail | |
<0.001 | polycystic ovary syndrome | NA | BeFree | Detail | |
0.004 | polycythemia vera | NA | BeFree,LHGDN | Detail | |
<0.001 | polyps | NA | BeFree | Detail | |
0.003 | pre-eclampsia | NA | LHGDN | Detail | |
0.005 | Prostatic Neoplasms | NA | LHGDN | Detail | |
<0.001 | psoriasis | NA | BeFree | Detail | |
0.080 | Reperfusion Injury | NA | RGD | Detail | |
0.002 | Respiratory Syncytial Virus Infections | NA | GAD | Detail | |
<0.001 | Sezary syndrome | NA | BeFree | Detail | |
0.080 | status epilepticus | NA | RGD | Detail | |
<0.001 | Stomach Neoplasms | SOCS-1 and SOCS-3 mRNA expression levels were lower in gastric tumor tissues tha... | BeFree | 25261987 | Detail |
<0.001 | Thrombocythemia, Essential | NA | BeFree | Detail | |
<0.001 | toxoplasmosis | NA | BeFree | Detail | |
0.004 | tuberculosis | STAT3 and SOCS3 may thus be targeted to improve the control of infection with M.... | BeFree,LHGDN | 25458989 | Detail |
<0.001 | pleural tuberculosis | NA | BeFree | Detail | |
<0.001 | Tuberculosis, Pulmonary | NA | BeFree | Detail | |
<0.001 | Vascular Diseases | NA | BeFree | Detail | |
<0.001 | Virus Diseases | NA | BeFree | Detail | |
0.080 | Helicobacter Infections | NA | RGD | Detail | |
<0.001 | T-Cell Lymphoma | NA | BeFree | Detail | |
<0.001 | Lymphoma, T-Cell, Cutaneous | NA | BeFree | Detail | |
<0.001 | benign neoplasm | NA | BeFree | Detail | |
<0.001 | Small cell carcinoma of lung | SOCS3 blocks HIF-1α expression to inhibit proliferation and angiogenesis of huma... | BeFree | 25695729 | Detail |
<0.001 | renal fibrosis | NA | BeFree | Detail | |
0.120 | Myocardial Ischemia | NA | CTD_human | Detail | |
<0.001 | congenital heart disease | NA | BeFree | Detail | |
<0.001 | Joint swelling | NA | BeFree | Detail | |
<0.001 | adrenoleukodystrophy | NA | BeFree | Detail | |
<0.001 | Dermatitis, Allergic Contact | NA | BeFree | Detail | |
<0.001 | Tumor Progression | NA | BeFree | Detail | |
0.003 | Ki-1+ Anaplastic Large Cell Lymphoma | NA | BeFree,LHGDN | Detail | |
0.003 | cholangiocarcinoma | NA | BeFree,LHGDN | Detail | |
<0.001 | pancreatic carcinoma | SOCS3 methylation in synergy with Reg3A overexpression promotes cell growth in p... | BeFree | 24996521 | Detail |
<0.001 | Anaplastic thyroid carcinoma | NA | BeFree | Detail | |
<0.001 | bone destruction | NA | BeFree | Detail | |
<0.001 | Fibrosis, Liver | NA | BeFree | Detail | |
0.001 | Malignant neoplasm of lung | NA | BeFree | Detail | |
0.080 | Sepsis | NA | RGD | Detail | |
<0.001 | Acute nephritis | NA | BeFree | Detail | |
<0.001 | Cancer of Head and Neck | NA | BeFree | Detail | |
<0.001 | Transitional cell carcinoma of bladder | Significance of suppressor of cytokine signaling-3 expression in bladder urothel... | BeFree | 25640370 | Detail |
<0.001 | Solid tumour | NA | BeFree | Detail | |
<0.001 | cervix carcinoma | NA | BeFree | Detail | |
<0.001 | Hyperplastic Polyp | NA | BeFree | Detail | |
<0.001 | Thyroid associated opthalmopathies | Genetic variations in the SOCS3 gene in patients with Graves' ophthalmopathy. | BeFree | 25770161 | Detail |
<0.001 | Malignant neoplasm of pancreas | SOCS3 methylation in synergy with Reg3A overexpression promotes cell growth in p... | BeFree | 24996521 | Detail |
<0.001 | Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site | NA | BeFree | Detail | |
0.001 | Malignant neoplasm of prostate | NA | BeFree | Detail | |
0.080 | Endotoxemia | NA | RGD | Detail | |
<0.001 | Acute hepatitis C | NA | BeFree | Detail | |
<0.001 | Chronic Kidney Insufficiency | NA | BeFree | Detail | |
<0.001 | Osteoarthritis, Knee | NA | BeFree | Detail | |
<0.001 | Adolescent idiopathic scoliosis | Lack of association between suppressor of cytokine signaling-3 gene polymorphism... | BeFree | 25034082 | Detail |
<0.001 | Metabolic syndrome X | NA | BeFree | Detail | |
<0.001 | Neurodegenerative Disorders | NA | BeFree | Detail | |
0.005 | Hepatitis C, Chronic | In chronic hepatitis C virus infection (CHC), expression of suppressor of cytoki... | BeFree,GAD | 24461080 | Detail |
0.005 | Hepatitis C, Chronic | Insulin resistance, adipokine profile and hepatic expression of SOCS-3 gene in c... | BeFree,GAD | 25132761 | Detail |
<0.001 | Thyroid carcinoma | NA | BeFree | Detail | |
<0.001 | Chronic idiopathic urticaria | NA | BeFree | Detail | |
<0.001 | Osteosarcoma of bone | NA | BeFree | Detail | |
<0.001 | Varicella-zoster virus infection | Suppressor of Cytokine Signaling 3 Expression Induced by Varicella-Zoster Virus ... | BeFree | 26072679 | Detail |
0.003 | Carcinogenesis | In summary, SOCS3 inactivation by methylation was demonstrated to act in synergy... | BeFree | 24996521 | Detail |
0.003 | Carcinogenesis | Suppressor of cytokine signaling 3 (SOCS3) is a major negative regulator of sign... | BeFree | 25695729 | Detail |
<0.001 | Leukemogenesis | Silencing due to methylation of suppressor of cytokine signaling-3 (SOCS-3), a n... | BeFree | 24969884 | Detail |
0.001 | prostate carcinoma | NA | BeFree | Detail | |
0.002 | breast carcinoma | NA | BeFree | Detail | |
<0.001 | inflammatory joint disease | NA | BeFree | Detail | |
0.004 | polycythemia vera | The evolving evidence that JAK2 V617F is not specific for polycythemia vera path... | BeFree | 16781479 | Detail |
0.004 | polycythemia vera | SOCS3 transcript levels were highest in patients with polycythemia vera and othe... | BeFree | 18815196 | Detail |
0.001 | Carcinoma of lung | NA | BeFree | Detail | |
<0.001 | Secondary malignant neoplasm of lymph node | NA | BeFree | Detail | |
<0.001 | colon carcinoma | NA | BeFree | Detail | |
<0.001 | stomach carcinoma | Low expression of SOCS-1 and SOCS-3 is a poor prognostic indicator for gastric c... | BeFree | 25261987 | Detail |
<0.001 | Carcinoma of bladder | Altered expression of suppressor of cytokine signaling -3 (SOCS-3) has been impl... | BeFree | 25640370 | Detail |
<0.001 | Central neuroblastoma | NA | BeFree | Detail | |
<0.001 | Varicella zoster | In conclusion, our data suggest that VZV infection induces SOCS3 expression, res... | BeFree | 26072679 | Detail |
<0.001 | malignant pleural mesothelioma | NA | BeFree | Detail | |
<0.001 | Arthritis, Collagen-Induced | NA | BeFree | Detail | |
0.080 | Arthritis, Experimental | NA | BeFree,RGD | Detail | |
<0.001 | West Nile viral infection | NA | BeFree | Detail | |
<0.001 | Squamous cell carcinoma of the head and neck | NA | BeFree | Detail | |
<0.001 | Persistent infection | NA | BeFree | Detail | |
0.001 | Chronic myeloproliferative disorder | NA | BeFree | Detail | |
<0.001 | Liver regeneration disorder | NA | BeFree | Detail | |
<0.001 | Classical Hodgkin's Lymphoma | NA | BeFree | Detail | |
<0.001 | pancreatic ductal adenocarcinoma | NA | BeFree | Detail | |
<0.001 | Refractory Neoplasm | NA | BeFree | Detail | |
0.011 | Mammary Neoplasms | NA | LHGDN | Detail | |
<0.001 | Hepatocarcinogenesis | NA | BeFree | Detail | |
<0.001 | Cancer Cell Growth | NA | BeFree | Detail | |
<0.001 | Xenograft Model | In transformed cells, enforced expression of SOCS3 or interfering with IL6 pathw... | BeFree | 24531711 | Detail |
<0.001 | colorectal cancer | NA | BeFree | Detail | |
<0.001 | Chronic Kidney Diseases | NA | BeFree | Detail | |
<0.001 | Glioblastoma multiforme | NA | BeFree | Detail | |
<0.001 | Cirrhosis | NA | BeFree | Detail | |
<0.001 | lateral meningocele syndrome | NA | BeFree | Detail | |
0.120 | DERMATITIS, ATOPIC, 4 | NA | CTD_human | Detail | |
<0.001 | campomelic dysplasia | NA | BeFree | Detail | |
0.126 | liver carcinoma | SOCS3 Genetic Polymorphism Is Associated With Clinical Features and Prognosis of... | BeFree,CTD_human,LHGDN | 26447993 | Detail |
<0.001 | Triple Negative Breast Neoplasms | SOCS3-mediated regulation of inflammatory cytokines in PTEN and p53 inactivated ... | BeFree | 24531711 | Detail |
<0.001 | Ulcerative colitis in remission | High suppressor of cytokine signaling-3 expression impairs STAT3-dependent prote... | BeFree | 25545374 | Detail |
0.008 | Infection | NA | LHGDN | Detail | |
<0.001 | adenocarcinoma | NA | BeFree | Detail | |
<0.001 | Primary myelofibrosis | Patients with primary MF showed aberrant expression of several genes involved in... | BeFree | 26408680 | Detail |
<0.001 | Anaplasia | NA | BeFree | Detail | |
<0.001 | arteriosclerosis | NA | BeFree | Detail | |
<0.001 | arthritis | NA | BeFree | Detail | |
0.004 | rheumatoid arthritis | NA | BeFree,GAD | Detail | |
0.003 | asthma | SOCS3 silencing attenuates eosinophil functions in asthma patients. | BeFree,GAD | 25764157 | Detail |
0.121 | atherosclerosis | NA | BeFree,CTD_human | Detail | |
<0.001 | Malignant neoplasm of urinary bladder | Altered expression of suppressor of cytokine signaling -3 (SOCS-3) has been impl... | BeFree | 25640370 | Detail |
<0.001 | Blast Phase | NA | BeFree | Detail | |
<0.001 | Brain Neoplasms | NA | BeFree | Detail | |
0.002 | Malignant neoplasm of breast | NA | BeFree | Detail | |
0.002 | Bronchiolitis, Viral | NA | GAD | Detail | |
<0.001 | Cachexia | NA | BeFree | Detail | |
<0.001 | Malignant tumor of colon | NA | BeFree | Detail | |
<0.001 | Malignant neoplasm of thyroid | NA | BeFree | Detail | |
<0.001 | Non-small cell lung carcinoma | NA | BeFree | Detail | |
<0.001 | renal cell carcinoma | NA | BeFree | Detail |
Annotation
Annotations
Descrption | Source | Links |
---|---|---|
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
FOS and SOCS3 were identified as candidate genes for CD and other three genes HELB, ZBTB16 and FAM10... | DisGeNET | Detail |
Prevention of SOCS3 expression or enhancement of IL-22/STAT3 signaling in IEC seems to be rational t... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
FOS and SOCS3 were identified as candidate genes for CD and other three genes HELB, ZBTB16 and FAM10... | DisGeNET | Detail |
NA | DisGeNET | Detail |
MicroRNA-185 targets SOCS3 to inhibit beta-cell dysfunction in diabetes. | DisGeNET | Detail |
MicroRNA-185 targets SOCS3 to inhibit beta-cell dysfunction in diabetes. | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
We found that elevated expression of suppressor of cytokine signaling 3 (SOCS3) following HBV infect... | DisGeNET | Detail |
NA | DisGeNET | Detail |
Short communication: serum-based assay accurately detects single nucleotide polymorphisms of IL28B a... | DisGeNET | Detail |
Short communication: serum-based assay accurately detects single nucleotide polymorphisms of IL28B a... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Obese influenza-free volunteers showed an increased basal expression of SOCS3, but not SOCS1. | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Thus SOCS-3 provides a suitable candidate for mechanisms underlying the development of imatinib resi... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Our findings suggest that IL6 and SOCS3 play important roles in COPD and have the potential to serve... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Low expression of SOCS-1 and SOCS-3 is a poor prognostic indicator for gastric cancer patients. | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
In transformed cells, enforced expression of SOCS3 or interfering with IL6 pathway via IL6R blockade... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
During influenza infection, SOCS1 and SOCS3 expression was higher in the lean infected volunteers in... | DisGeNET | Detail |
In chronic hepatitis C virus infection (CHC), expression of suppressor of cytokine signalling-3 (SOC... | DisGeNET | Detail |
NA | DisGeNET | Detail |
Gene EP of TNF, IL-6, IL-8, CHIT1, BMP4, CCL3, CCL18, MMP9, RANKL, OPG, DC-STAMP and SOCS3 were asse... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
SOCS-1 and SOCS-3 mRNA expression levels were lower in gastric tumor tissues than in matched normal ... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
STAT3 and SOCS3 may thus be targeted to improve the control of infection with M. tuberculosis or the... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
SOCS3 blocks HIF-1α expression to inhibit proliferation and angiogenesis of human small cell lung ca... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
SOCS3 methylation in synergy with Reg3A overexpression promotes cell growth in pancreatic cancer. | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Significance of suppressor of cytokine signaling-3 expression in bladder urothelial carcinoma in rel... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Genetic variations in the SOCS3 gene in patients with Graves' ophthalmopathy. | DisGeNET | Detail |
SOCS3 methylation in synergy with Reg3A overexpression promotes cell growth in pancreatic cancer. | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Lack of association between suppressor of cytokine signaling-3 gene polymorphism and susceptibility ... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
In chronic hepatitis C virus infection (CHC), expression of suppressor of cytokine signalling-3 (SOC... | DisGeNET | Detail |
Insulin resistance, adipokine profile and hepatic expression of SOCS-3 gene in chronic hepatitis C. | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Suppressor of Cytokine Signaling 3 Expression Induced by Varicella-Zoster Virus Infection Results in... | DisGeNET | Detail |
In summary, SOCS3 inactivation by methylation was demonstrated to act in synergy with Reg3A overexpr... | DisGeNET | Detail |
Suppressor of cytokine signaling 3 (SOCS3) is a major negative regulator of signal transducer and ac... | DisGeNET | Detail |
Silencing due to methylation of suppressor of cytokine signaling-3 (SOCS-3), a negative regulator ge... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
The evolving evidence that JAK2 V617F is not specific for polycythemia vera pathogenesis and the dev... | DisGeNET | Detail |
SOCS3 transcript levels were highest in patients with polycythemia vera and other JAK2 V617F positiv... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Low expression of SOCS-1 and SOCS-3 is a poor prognostic indicator for gastric cancer patients. | DisGeNET | Detail |
Altered expression of suppressor of cytokine signaling -3 (SOCS-3) has been implicated in various ty... | DisGeNET | Detail |
NA | DisGeNET | Detail |
In conclusion, our data suggest that VZV infection induces SOCS3 expression, resulting in modulation... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
In transformed cells, enforced expression of SOCS3 or interfering with IL6 pathway via IL6R blockade... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
SOCS3 Genetic Polymorphism Is Associated With Clinical Features and Prognosis of Hepatocellular Carc... | DisGeNET | Detail |
SOCS3-mediated regulation of inflammatory cytokines in PTEN and p53 inactivated triple negative brea... | DisGeNET | Detail |
High suppressor of cytokine signaling-3 expression impairs STAT3-dependent protective effects of int... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Patients with primary MF showed aberrant expression of several genes involved in maintaining BM home... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
SOCS3 silencing attenuates eosinophil functions in asthma patients. | DisGeNET | Detail |
NA | DisGeNET | Detail |
Altered expression of suppressor of cytokine signaling -3 (SOCS-3) has been implicated in various ty... | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
NA | DisGeNET | Detail |
Overlapped Transcript Coordinates
Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
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Overlapped Transcript
Gene | Transcript ID | Chromosome | Start | Stop | Links |
---|
- Gene
- -
- dbSNP
- rs386626619 dbSNP
- Genome
- hg19
- Position
- chr17:76,352,859-76,356,158
- Variant Type
- snv
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