Annotation Detail

Information
Associated Genes
SOCS3
Associated Variants
SOCS3 MUTATION
SOCS3 MUTATION
Associated Disease
ulcerative colitis
Source Database
DisGeNET
Description
Prevention of SOCS3 expression or enhancement of IL-22/STAT3 signaling in IEC seems to be rational therapeutic strategies for UC remission maintenance.
Pubmed
25545374
Section of the abstract supporting the evidence
CONCLUSIONS
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
10
Original source reporting the Gene Disease association
BeFree,LHGDN
DisGENET score for the Gene Disease association
0.00381011773078838
Drugs