Annotation Detail
Information
- Associated Genes
- SOCS3
- Associated Variants
-
SOCS3 MUTATION
SOCS3 MUTATION - Associated Disease
- Small cell carcinoma of lung
- Source Database
- DisGeNET
- Description
- SOCS3 blocks HIF-1α expression to inhibit proliferation and angiogenesis of human small cell lung cancer by downregulating activation of Akt, but not STAT3.
- Pubmed
- 25695729
- Section of the abstract supporting the evidence
- TITLE
- Number of the section of the abstract supporting the evidence
- 0
- Number of the sentence supporting the evidence
- 0
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs