Annotation Detail

Information
Associated Genes
SOCS3
Associated Variants
SOCS3 MUTATION
SOCS3 MUTATION
Associated Disease
Primary myelofibrosis
Source Database
DisGeNET
Description
Patients with primary MF showed aberrant expression of several genes involved in maintaining BM homeostasis and our findings suggest that treatment with lenalidomide plus prednisone up-regulates SOCS3.
Pubmed
26408680
Section of the abstract supporting the evidence
CONCLUSION
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs