chr6:32148745:> Detail (hg19)

Information

Genome

Assembly Position
hg19 chr6:32,148,745-32,152,099
hg38 chr6:32,180,968-32,184,322 

HGVS

Type Transcript Protein
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

[No Data.]

Prediction

[No Data.]

ClinVar

Clinical Significance
Review star [No Data.]
Show details
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score Disease name Description Source Pubmed Links
0.005 squamous cell carcinoma NA LHGDN Detail
0.086 Cardiovascular Diseases NA BeFree,LHGDN,RGD Detail
0.080 Carotid Artery Diseases NA RGD Detail
0.080 intracranial aneurysm NA RGD Detail
0.085 brain ischemia NA LHGDN,RGD Detail
0.080 Transient ischemic attack NA RGD Detail
0.003 chondrosarcoma NA LHGDN Detail
0.002 ulcerative colitis NA GAD Detail
<0.001 Colonic Neoplasms NA BeFree Detail
0.083 Colorectal Neoplasms NA LHGDN,RGD Detail
0.003 Coronary Arteriosclerosis NA BeFree Detail
0.003 Coronary heart disease NA BeFree Detail
<0.001 Crohn Disease RAGE gene three polymorphisms with Crohn's disease susceptibility in Chinese Han... BeFree 24605038 Detail
<0.001 cystic fibrosis NA BeFree Detail
0.003 Cessation of life NA LHGDN Detail
<0.001 Presenile dementia NA BeFree Detail
0.003 Dementia, Vascular NA LHGDN Detail
0.003 dermatomyositis NA LHGDN Detail
0.003 Diabetes NA BeFree Detail
0.007 diabetes mellitus NA BeFree,LHGDN Detail
0.080 Diabetes Mellitus, Experimental NA RGD Detail
0.008 Diabetes Mellitus, Insulin-Dependent NA BeFree,GAD Detail
0.104 Diabetes Mellitus, Non-Insulin-Dependent Our study indicated that the 2184A/G polymorphism in the RAGE gene was significa... BeFree,GAD,LHGDN,RGD 26770981 Detail
0.129 Diabetic Angiopathies NA BeFree,CTD_human,LHGDN Detail
0.003 diabetic ketoacidosis NA LHGDN Detail
0.101 Diabetic Nephropathy Our study indicated that the 2184A/G polymorphism in the RAGE gene was significa... BeFree,GAD,LHGDN,RGD 26770981 Detail
0.003 Diabetic Neuropathies NA LHGDN Detail
0.102 diabetic retinopathy NA BeFree,GAD,LHGDN,RGD Detail
0.083 Fibrosis NA LHGDN,RGD Detail
0.080 Gastrointestinal Diseases NA RGD Detail
<0.001 Hodgkin Disease NA BeFree Detail
<0.001 Huntington disease NA BeFree Detail
0.080 Hyperalgesia NA RGD Detail
0.121 hyperglycemia NA BeFree,CTD_human Detail
0.081 Hypertensive disease NA BeFree,RGD Detail
0.080 pulmonary hypertension NA RGD Detail
0.123 Inflammation NA CTD_human,LHGDN Detail
<0.001 ischemia NA BeFree Detail
<0.001 Transient ischemia NA BeFree Detail
0.006 Kidney Diseases NA BeFree,LHGDN Detail
0.002 Kidney Failure, Chronic NA GAD Detail
<0.001 Myeloid Leukemia, Chronic NA BeFree Detail
0.003 Lung diseases NA BeFree,GAD Detail
0.003 Chronic Obstructive Airway Disease The variant at HTR4 was associated with COPD in never-smokers, and the SNP in AG... BeFree,GAD 24286382 Detail
0.003 Lung Neoplasms NA BeFree,LHGDN Detail
0.002 Lupus Erythematosus, Systemic NA GAD Detail
<0.001 Malignant neoplasm of stomach Autophagy-mediated HMGB1 release promotes gastric cancer cell survival via RAGE ... BeFree 25652880 Detail
0.003 melanoma Diminished levels of the soluble form of RAGE are related to poor survival in ma... BeFree,LHGDN 26018980 Detail
<0.001 multiple sclerosis NA BeFree Detail
0.083 myocardial infarction NA BeFree,GAD,RGD Detail
0.080 Myocardial Reperfusion Injury NA RGD Detail
<0.001 myositis HMGB1 and RAGE in skeletal muscle inflammation: Implications for protein accumul... BeFree 26048613 Detail
0.004 Neoplasm Metastasis AGE-RAGE (a receptor of AGEs) is also correlated with metastasis and angiogenesi... BeFree,LHGDN 25330185 Detail
0.003 Neuronal Ceroid-Lipofuscinoses NA LHGDN Detail
<0.001 obesity NA BeFree Detail
0.086 Degenerative polyarthritis NA BeFree,LHGDN,RGD Detail
0.080 osteoporosis NA RGD Detail
0.120 Pancreatic Diseases NA CTD_human Detail
0.008 Pancreatic Neoplasm NA GAD,LHGDN Detail
0.080 periodontitis NA RGD Detail
<0.001 pneumonia NA BeFree Detail
0.005 Prostatic Neoplasms NA LHGDN Detail
<0.001 pulmonary emphysema NA BeFree Detail
0.080 pulmonary fibrosis NA RGD Detail
0.080 Respiratory Distress Syndrome, Adult NA RGD Detail
0.001 Retinal Diseases NA BeFree Detail
0.003 rhabdomyosarcoma NA LHGDN Detail
0.003 sarcoidosis NA LHGDN Detail
0.080 Subarachnoid Hemorrhage NA RGD Detail
0.080 thromboangiitis obliterans NA RGD Detail
0.080 Tongue Neoplasms NA RGD Detail
0.003 tuberculosis NA LHGDN Detail
0.080 uremia NA RGD Detail
0.001 Vascular Diseases NA BeFree Detail
<0.001 Polycystic Kidney, Autosomal Dominant NA BeFree Detail
0.003 polymyositis NA LHGDN Detail
0.104 Diabetes Mellitus, Non-Insulin-Dependent The -429 T/C and Gly82Ser RAGE polymorphisms were found to be significantly asso... BeFree 24418399 Detail
0.003 Coronary heart disease Is there any association between GLY82 ser polymorphism of rage gene and Turkish... BeFree 21947881 Detail
0.088 Cerebrovascular accident Among the studied polymorphisms, only the polymorphism at 82G/S of RAGE gene was... BeFree 24107402 Detail
<0.001 Microalbuminuria Association study of G1704T and G82S polymorphisms of RAGE gene for microalbumin... BeFree 15798956 Detail
0.129 Diabetic Angiopathies The study was designed to evaluate the association of -374T/A and -429T/C polymo... BeFree 24418399 Detail
0.001 Retinal Diseases Lack of association between Gly82Ser, 1704G/T and 2184A/G of RAGE gene polymorph... BeFree 22427038 Detail
0.003 Coronary heart disease Association of AGER gene G82S polymorphism with the severity of coronary artery ... BeFree 21521347 Detail
0.003 Coronary Arteriosclerosis Is there any association between GLY82 ser polymorphism of rage gene and Turkish... BeFree 21947881 Detail
0.008 Diabetes Mellitus, Insulin-Dependent Human RAGE GLY82SER dimorphism and HLA class II DRB1-DQA1-DQB1 haplotypes in typ... BeFree 10553500 Detail
<0.001 colorectal cancer In conclusion, the RAGE gene Gly82Ser polymorphism may confer not only an increa... BeFree 24248547 Detail
0.102 diabetic retinopathy G82S polymorphism in the RAGE gene is associated with DR and G-A haplotype conta... BeFree 19542745 Detail
0.017 coronary artery disease Association of AGER gene G82S polymorphism with the severity of coronary artery ... BeFree 21521347 Detail
0.104 Diabetes Mellitus, Non-Insulin-Dependent To investigate the association between diabetic retinopathy (DR) in type 2 diabe... BeFree 22354095 Detail
0.102 diabetic retinopathy Relation between polymorphisms G1704T and G82S of rage gene and diabetic retinop... BeFree 15942086 Detail
<0.001 Ischemic stroke Among the studied polymorphisms, only the polymorphism at 82G/S of RAGE gene was... BeFree 24107402 Detail
0.081 Hypertensive disease The allele frequencies and genotype distribution combinations of the -429T/C, 17... BeFree 20668462 Detail
0.102 diabetic retinopathy The findings suggest that the G82S polymorphism in the RAGE gene is associated w... BeFree 24303504 Detail
0.102 diabetic retinopathy Association of Gly82Ser polymorphism in the RAGE gene with diabetic retinopathy ... BeFree 12477623 Detail
0.104 Diabetes Mellitus, Non-Insulin-Dependent This study aims to investigate the frequency of Gly82Ser polymorphism in exon 3 ... BeFree 12477623 Detail
<0.001 Ischemic Cerebrovascular Accident Among the studied polymorphisms, only the polymorphism at 82G/S of RAGE gene was... BeFree 24107402 Detail
0.017 coronary artery disease Is there any association between GLY82 ser polymorphism of rage gene and Turkish... BeFree 21947881 Detail
0.003 Coronary Arteriosclerosis Association of AGER gene G82S polymorphism with the severity of coronary artery ... BeFree 21521347 Detail
0.102 diabetic retinopathy To investigate the association between diabetic retinopathy (DR) in type 2 diabe... BeFree 22354095 Detail
0.003 Myocardial Ischemia NA BeFree,LHGDN Detail
<0.001 Malignant neoplasm of mouth Cell migration is regulated by AGE-RAGE interaction in human oral cancer cells i... BeFree 25330185 Detail
<0.001 Malignant neoplasm of mouth RAGE gene polymorphism and environmental factor in the risk of oral cancer. BeFree 25582438 Detail
<0.001 Malignant neoplasm of testis NA BeFree Detail
<0.001 Tumor Progression Blocking RAGE‑HMGB1 interaction with antibody or siRNA suppressed the ERK1/2 act... BeFree 25652880 Detail
<0.001 Lip and oral cavity carcinoma Cell migration is regulated by AGE-RAGE interaction in human oral cancer cells i... BeFree 25330185 Detail
<0.001 Lip and oral cavity carcinoma RAGE gene polymorphism and environmental factor in the risk of oral cancer. BeFree 25582438 Detail
<0.001 Reactive systemic amyloidosis NA BeFree Detail
<0.001 Inclusion Body Myositis (disorder) HMGB1 and RAGE in skeletal muscle inflammation: Implications for protein accumul... BeFree 26048613 Detail
<0.001 Anaplastic thyroid carcinoma Mechanistic investigations showed that S100A8 promotes ATC cell proliferation th... BeFree 25423568 Detail
0.080 Erectile dysfunction NA RGD Detail
<0.001 Malignant neoplasm of lung NA BeFree Detail
0.080 Acute Lung Injury NA RGD Detail
0.080 Hyperoxia NA RGD Detail
0.080 Sepsis NA RGD Detail
<0.001 Chronic Periodontitis NA BeFree Detail
0.003 Impaired glucose tolerance NA LHGDN Detail
0.080 Lung Injury NA RGD Detail
<0.001 Restenosis NA BeFree Detail
0.008 Complications of Diabetes Mellitus NA GAD,LHGDN Detail
<0.001 Disseminated Malignant Neoplasm NA BeFree Detail
<0.001 Malignant neoplasm of prostate NA BeFree Detail
<0.001 dementia NA BeFree Detail
0.080 Peritoneal Fibrosis NA RGD Detail
<0.001 Hodgkin Disease The A419C (E111A) polymorphism of the GLO I gene is associated with vascular dis... BeFree 20185929 Detail
0.001 Vascular Diseases The A419C (E111A) polymorphism of the GLO I gene is associated with vascular dis... BeFree 20185929 Detail
<0.001 Huntington disease The A419C (E111A) polymorphism of the GLO I gene is associated with vascular dis... BeFree 20185929 Detail
<0.001 Carcinogenesis The present study aimed to assess the influences of RAGE gene polymorphisms, com... BeFree 25582438 Detail
<0.001 Carcinogenesis RAGE is a central driver of tumorigenesis by sustaining an inflammatory tumor mi... BeFree 26018980 Detail
<0.001 prostate carcinoma NA BeFree Detail
<0.001 Epithelial ovarian cancer NA BeFree Detail
<0.001 breast carcinoma NA BeFree Detail
<0.001 Carcinoma of lung NA BeFree Detail
<0.001 stomach carcinoma Autophagy-mediated HMGB1 release promotes gastric cancer cell survival via RAGE ... BeFree 25652880 Detail
<0.001 Microalbuminuria NA BeFree Detail
0.080 Infarction, Middle Cerebral Artery NA RGD Detail
0.120 Lewy Body Disease NA CTD_human Detail
0.080 Diabetic Cardiomyopathies NA RGD Detail
<0.001 Endothelial dysfunction NA BeFree Detail
<0.001 Ischemic stroke NA BeFree Detail
0.003 Mammary Neoplasms NA LHGDN Detail
<0.001 Hepatocarcinogenesis In this study, the impact of RAGE gene polymorphisms on the susceptibility to he... BeFree 26313784 Detail
<0.001 colorectal cancer NA BeFree Detail
0.003 Sjogren's syndrome NA LHGDN Detail
0.003 Idiopathic Pulmonary Fibrosis NA LHGDN Detail
<0.001 Malformations of Cortical Development NA BeFree Detail
0.017 coronary artery disease NA BeFree,LHGDN Detail
<0.001 liver carcinoma NA BeFree Detail
<0.001 Nasopharyngeal carcinoma NA BeFree Detail
<0.001 Plaque, Amyloid NA BeFree Detail
0.125 Pulmonary function (finding) NA GAD,GWASCAT Detail
<0.001 Ischemic Cerebrovascular Accident NA BeFree Detail
<0.001 AA amyloidosis NA BeFree Detail
0.003 adenocarcinoma NA BeFree,LHGDN Detail
0.080 Albuminuria NA RGD Detail
0.096 Alzheimer's disease NA GAD,LHGDN,RGD Detail
0.003 amyloidosis NA LHGDN Detail
<0.001 aortic aneurysm The present study was aimed at analyzing the potential association between the R... BeFree 25789318 Detail
0.080 Aortic Diseases NA RGD Detail
0.001 arteriosclerosis NA BeFree Detail
0.129 rheumatoid arthritis NA BeFree,CTD_human,LHGDN Detail
0.080 asthma NA RGD Detail
0.214 atherosclerosis NA BeFree,CTD_human,GAD,LHGDN,RGD Detail
<0.001 autistic disorder NA BeFree Detail
<0.001 Malignant neoplasm of breast NA BeFree Detail
0.003 Non-small cell lung carcinoma NA BeFree,GAD Detail
Annotation

Annotations

DescrptionSourceLinks
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
RAGE gene three polymorphisms with Crohn's disease susceptibility in Chinese Han population. DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Our study indicated that the 2184A/G polymorphism in the RAGE gene was significantly associated with... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Our study indicated that the 2184A/G polymorphism in the RAGE gene was significantly associated with... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The variant at HTR4 was associated with COPD in never-smokers, and the SNP in AGER was associated wi... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Autophagy-mediated HMGB1 release promotes gastric cancer cell survival via RAGE activation of extrac... DisGeNET Detail
Diminished levels of the soluble form of RAGE are related to poor survival in malignant melanoma. DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
HMGB1 and RAGE in skeletal muscle inflammation: Implications for protein accumulation in inclusion b... DisGeNET Detail
AGE-RAGE (a receptor of AGEs) is also correlated with metastasis and angiogenesis. DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The -429 T/C and Gly82Ser RAGE polymorphisms were found to be significantly associated with the deve... DisGeNET Detail
Is there any association between GLY82 ser polymorphism of rage gene and Turkish diabetic and non di... DisGeNET Detail
Among the studied polymorphisms, only the polymorphism at 82G/S of RAGE gene was associated with the... DisGeNET Detail
Association study of G1704T and G82S polymorphisms of RAGE gene for microalbuminuria in Japanese typ... DisGeNET Detail
The study was designed to evaluate the association of -374T/A and -429T/C polymorphism in the promot... DisGeNET Detail
Lack of association between Gly82Ser, 1704G/T and 2184A/G of RAGE gene polymorphisms and retinopathy... DisGeNET Detail
Association of AGER gene G82S polymorphism with the severity of coronary artery disease in Chinese H... DisGeNET Detail
Is there any association between GLY82 ser polymorphism of rage gene and Turkish diabetic and non di... DisGeNET Detail
Human RAGE GLY82SER dimorphism and HLA class II DRB1-DQA1-DQB1 haplotypes in type 1 diabetes. DisGeNET Detail
In conclusion, the RAGE gene Gly82Ser polymorphism may confer not only an increased risk of CRC but ... DisGeNET Detail
G82S polymorphism in the RAGE gene is associated with DR and G-A haplotype containing 1704G and 82S ... DisGeNET Detail
Association of AGER gene G82S polymorphism with the severity of coronary artery disease in Chinese H... DisGeNET Detail
To investigate the association between diabetic retinopathy (DR) in type 2 diabetes mellitus and thr... DisGeNET Detail
Relation between polymorphisms G1704T and G82S of rage gene and diabetic retinopathy in Japanese typ... DisGeNET Detail
Among the studied polymorphisms, only the polymorphism at 82G/S of RAGE gene was associated with the... DisGeNET Detail
The allele frequencies and genotype distribution combinations of the -429T/C, 1704G/T and G82S polym... DisGeNET Detail
The findings suggest that the G82S polymorphism in the RAGE gene is associated with DR risk, and G82... DisGeNET Detail
Association of Gly82Ser polymorphism in the RAGE gene with diabetic retinopathy in type II diabetic ... DisGeNET Detail
This study aims to investigate the frequency of Gly82Ser polymorphism in exon 3 of the receptor for ... DisGeNET Detail
Among the studied polymorphisms, only the polymorphism at 82G/S of RAGE gene was associated with the... DisGeNET Detail
Is there any association between GLY82 ser polymorphism of rage gene and Turkish diabetic and non di... DisGeNET Detail
Association of AGER gene G82S polymorphism with the severity of coronary artery disease in Chinese H... DisGeNET Detail
To investigate the association between diabetic retinopathy (DR) in type 2 diabetes mellitus and thr... DisGeNET Detail
NA DisGeNET Detail
Cell migration is regulated by AGE-RAGE interaction in human oral cancer cells in vitro. DisGeNET Detail
RAGE gene polymorphism and environmental factor in the risk of oral cancer. DisGeNET Detail
NA DisGeNET Detail
Blocking RAGE‑HMGB1 interaction with antibody or siRNA suppressed the ERK1/2 activation and gastric ... DisGeNET Detail
Cell migration is regulated by AGE-RAGE interaction in human oral cancer cells in vitro. DisGeNET Detail
RAGE gene polymorphism and environmental factor in the risk of oral cancer. DisGeNET Detail
NA DisGeNET Detail
HMGB1 and RAGE in skeletal muscle inflammation: Implications for protein accumulation in inclusion b... DisGeNET Detail
Mechanistic investigations showed that S100A8 promotes ATC cell proliferation through an interaction... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The A419C (E111A) polymorphism of the GLO I gene is associated with vascular disease in hemodialysis... DisGeNET Detail
The A419C (E111A) polymorphism of the GLO I gene is associated with vascular disease in hemodialysis... DisGeNET Detail
The A419C (E111A) polymorphism of the GLO I gene is associated with vascular disease in hemodialysis... DisGeNET Detail
The present study aimed to assess the influences of RAGE gene polymorphisms, combined with environme... DisGeNET Detail
RAGE is a central driver of tumorigenesis by sustaining an inflammatory tumor microenvironment. DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Autophagy-mediated HMGB1 release promotes gastric cancer cell survival via RAGE activation of extrac... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
In this study, the impact of RAGE gene polymorphisms on the susceptibility to hepatocarcinogenesis w... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The present study was aimed at analyzing the potential association between the RAGE gene polymorphis... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail

Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
dbSNP
rs386556293 dbSNP
Genome
hg19
Position
chr6:32,148,745-32,152,099
Variant Type
snv
Genome browser