Annotation Detail
Information
- Associated Genes
- AGER
- Associated Variants
-
AGER MUTATION
AGER MUTATION
AGER p.Gly82Ser (p.G82S) ( ENST00000375055.6, ENST00000375067.7, ENST00000375069.7, ENST00000375070.7, ENST00000375076.9, ENST00000438221.6, ENST00000538695.2 )
AGER p.Gly82Ser (p.G82S) ( ENST00000375055.6, ENST00000375067.7, ENST00000375069.7, ENST00000375070.7, ENST00000375076.9, ENST00000438221.6, ENST00000538695.2 ) - Associated Disease
- Diabetes Mellitus, Non-Insulin-Dependent
- Source Database
- DisGeNET
- Description
- The -429 T/C and Gly82Ser RAGE polymorphisms were found to be significantly associated with the development of macrovascular and microvascular complications, respectively, in T2DM subjects while -374A allele showed reduced risk towards the development of macrovascular complications.
- Pubmed
- 24418399
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.104450969662207
- Year of publication
- 2013
Drugs