Annotation Detail
Information
- Associated Genes
- AGER
- Associated Variants
-
AGER MUTATION
AGER MUTATION - Associated Disease
- Tumor Progression
- Source Database
- DisGeNET
- Description
- Blocking RAGE‑HMGB1 interaction with antibody or siRNA suppressed the ERK1/2 activation and gastric cancer cell growth, indicating that RAGE-mediated ERK1/2 signaling was necessary for tumor progression.
- Pubmed
- 25652880
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 13
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs