diabetic ketoacidosis
Information
- Disease name
- diabetic ketoacidosis
- Disease ID
- DOID:1837
- Description
- "A metabolic acidosis that is characterized by the shift of acid-base status of the body toward the acid side accompanied by the accumulation of ketone bodies in body tissues and fluids, resulting from uncontrolled diabetes mellitus." [url:https\://medlineplus.gov/ency/article/000320.htm, url:https\://www.mayoclinic.org/diseases-conditions/diabetic-ketoacidosis/symptoms-causes/syc-20371551]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT02443415 | Completed | Diabetic Ketoacidosis: Brain Morphology and Cognition | February 2015 | October 1, 2017 | |
| NCT00426413 | Completed | Ketosis Prone Diabetes in African-Americans | May 2007 | August 2010 | |
| NCT00589680 | Completed | Compliance With American Diabetes Association Treatment Guidelines for Adult Ketoacidosis | December 2007 | July 2008 | |
| NCT00590044 | Completed | Phase 4 | Basal Insulin in the Management of Patients With Diabetic Ketoacidosis (DKA) | December 2007 | August 2008 |
| NCT00629707 | Completed | N/A | Cerebral Edema in Pediatric Diabetic Ketoacidosis | June 2008 | June 2011 |
| NCT00920725 | Completed | N/A | Subcutaneous Aspart Insulin to Treat Diabetic Ketoacidosis (DKA) and Beta-Hydroxybutyrate Testing in DKA | January 2005 | December 2007 |
| NCT01365793 | Completed | Phase 3 | Randomized Control Trial of Fluid Therapy for Pediatric Diabetic Ketoacidosis | November 2010 | January 2017 |
| NCT01753921 | Completed | Evaluation of a Non-invasive Brain Compliance Measurement Device | November 2011 | October 2016 | |
| NCT02006342 | Completed | N/A | Effectiveness of Subcutaneous Glargine On The Time To Closure of The Anion Gap in Patients Presenting to the Emergency Department With Diabetic Keto-acidosis | November 2012 | April 2013 |
| NCT00179127 | Completed | N/A | Use of Insulin Glargine to Treat Diabetic Ketoacidosis | August 2004 | September 2012 |
| NCT02930044 | Completed | N/A | Early Subcutaneous Insulin Glargine Plus Standard of Care for Treatment of Diabetic Ketoacidosis | October 2016 | November 1, 2021 |
| NCT03107208 | Completed | Phase 4 | Early Glargine (Lantus) in DKA Management in Children With Type 1 Diabetes | July 21, 2017 | March 13, 2021 |
| NCT03128229 | Completed | Diabetic Kidney Alarm (DKA) Study | June 1, 2017 | December 13, 2019 | |
| NCT03182569 | Completed | N/A | Flexible Catheter for Insulin in Diabetes | December 11, 2016 | April 9, 2018 |
| NCT03660189 | Completed | N/A | Two Bag System for Diabetic Ketoacidosis | September 17, 2018 | June 15, 2023 |
| NCT04017221 | Completed | Safety of Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors Among Patients With Type 2 Diabetes | October 1, 2018 | December 1, 2019 | |
| NCT04656236 | Completed | N/A | Metabolic Effects of Exogenous 3-hydroxybutyrate in Patients With Type 1 Diabetes and Healthy Controls | January 1, 2021 | March 1, 2022 |
| NCT04825639 | Completed | Identifying Risk Factors for Developing AKI in Sepsis | March 15, 2021 | March 31, 2022 | |
| NCT04926740 | Completed | N/A | Intravenous Fluids in Adults With Diabetic Ketoacidosis in the Emergency Department | October 12, 2021 | December 7, 2022 |
| NCT04940897 | Completed | N/A | Use of Blood Ketone Meters to Improve Ambulance Hyperglycaemia Care | October 25, 2021 | February 23, 2023 |
| NCT04977011 | Completed | N/A | Effectiveness of Music Intervention on Anxiety and Physiological Responses in Critical Ill Patient | January 2, 2019 | July 30, 2019 |
| NCT06251895 | Completed | Association of Systemic Immune-inflammation Index and Severity of Diabetic Ketoacidosis in Type 1 Diabetes Mellitus | August 1, 2021 | November 11, 2023 | |
| NCT06327737 | Completed | Diabetic Ketoacidosis Diagnosis and Management | December 15, 2020 | March 15, 2023 | |
| NCT06186245 | Enrolling by invitation | N/A | Starvation in the Treatment of Diabetic Ketoacidosis | December 27, 2023 | December 2024 |
| NCT05752279 | Not yet recruiting | Phase 3 | Balanced Multi-Electrolyte Solution Versus Saline Trial for Diabetic KetoAcidosis | March 2024 | June 2026 |
| NCT05867797 | Not yet recruiting | Risk Factors and Outcomes of Acute Kidney Injury in Patients With Diabetic Ketoacidosis at Sohag University Hospital. | May 20, 2023 | November 20, 2024 | |
| NCT05649891 | Not yet recruiting | N/A | Checklists Resuscitation Emergency Department | September 2023 | March 2024 |
| NCT05666895 | Not yet recruiting | Role of CBC as a Prognostic Marker for DKA Patients | January 1, 2023 | July 1, 2024 | |
| NCT03717896 | Recruiting | Phase 2 | Thiamine as Adjunctive Therapy for Diabetic Ketoacidosis | November 21, 2018 | October 1, 2024 |
| NCT05383404 | Recruiting | Clinical and Laboratory Parameters Associated With Different Degrees of Dehydration Among Children With Diabetic Ketoacidosis | June 25, 2022 | June 2023 | |
| NCT05402579 | Recruiting | Diabetic Ketoacidosis From New SGLT2i: Can Genomics Estimate Risk | July 29, 2022 | June 6, 2024 | |
| NCT05443802 | Recruiting | N/A | Comparison of a Low Dose to a Standard Dose of Insulin in Adult DKA in ICU to Reduce Metabolic Complications | August 16, 2022 | February 16, 2025 |
| NCT04567225 | Terminated | Phase 4 | Early Basal Insulin Administration in Adult Diabetic Ketoacidosis Management | October 1, 2020 | August 27, 2021 |
| NCT02548494 | Terminated | N/A | Early Administration of Long-acting Insulin Treatment of Diabetic Ketoacidosis in Pediatric Type 1 Diabetes | November 2015 | February 1, 2019 |
| NCT02950181 | Terminated | N/A | Descriptive Analysis of Near Infrared Spectroscopy in Critically Ill and Injured Pediatric and Neonatal Patients | July 29, 2014 | January 1, 2019 |
| NCT03066440 | Terminated | Phase 4 | Double Blinded Randomized Control Trial of Types of IVF in Children With DKA | September 1, 2018 | March 18, 2024 |
| NCT04234867 | Terminated | Phase 1 | Study to Explore the Effect of Dapagliflozin and Stress in Adolescent and Adult Subjects With Type 1 Diabetes (T1D) | May 18, 2022 | August 26, 2022 |
| NCT05155917 | Unknown status | Phase 2 | Concurrent Subcutaneous Basal Insulin and Intravenous Insulin Pump in Hyperglycemic Crisis Patients Under Critical Care | March 1, 2022 | January 2024 |
| NCT02130180 | Unknown status | DKA Optic Ultrasound | April 2014 | October 2015 | |
| NCT05439928 | Unknown status | N/A | Remote Glucose Monitoring System in Hospitalized Patients With Diabetic Ketoacidosis (DKA) | July 2022 | July 2023 |
| NCT04819178 | Withdrawn | Real Life Evaluation of SGLT2 Use in Type 1 Diabetes | June 1, 2021 | December 1, 2021 |
- Disase is a (Disease Ontology)
- DOID:0050758
- Cross Reference ID (Disease Ontology)
- ICD9CM:250.1
- Cross Reference ID (Disease Ontology)
- MESH:D016883
- Cross Reference ID (Disease Ontology)
- MIM:612227
- Cross Reference ID (Disease Ontology)
- NCI:C50530
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:154671004
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0011880
- Exact Synonym (Disease Ontology)
- DIABETES MELLITUS, KETOSIS-PRONE
- Exact Synonym (Disease Ontology)
- ketosis-prone diabetes mellitus
- HPO alt_id (Human Phenotype Ontology)
- HP:0008253
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0001953
- MedGen concept unique identifier (MedGen Concept name)
- C0011880
- MedGen unique identifier (MedGen Concept name)
- 8351
- MeSH unique ID (MeSH (Medical Subject Headings))
- D016883