metabolic acidosis
Information
- Disease name
- metabolic acidosis
- Disease ID
- DOID:0050758
- Description
- "An acquired metabolic disease that characterized by excessive production of acid." [url:http\://en.wikipedia.org/wiki/Metabolic_acidosis, url:https\://medlineplus.gov/ency/article/000335.htm]
Disease area statistics
Chromosome band
Annotation
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT04010630 | Active, not recruiting | N/A | Sodium Bicarbonate for the Treatment of Severe Metabolic Acidosis With Moderate or Severe Acute Kidney Injury in ICU | October 7, 2019 | June 19, 2024 |
| NCT01075750 | Completed | Perioperative Fluid Management in Patients Receiving Cadaveric Renal Transplants | June 2010 | February 2013 | |
| NCT01293266 | Completed | N/A | Effect of Propofol and Sevoflurane on Lactate During Anesthesia for Pediatric Heart Catheterisation | June 2009 | August 2010 |
| NCT01295190 | Completed | Substitution of Propofol by Sevoflurane During Pediatric Cardiopulmonary Bypass | June 2009 | August 2010 | |
| NCT01452412 | Completed | Phase 2/Phase 3 | Alkali Therapy in Chronic Kidney Disease | October 2011 | August 2016 |
| NCT00913796 | Completed | Phase 2 | Metabolic Acidosis in Renal Transplant Patients | December 2007 | March 2010 |
| NCT01777178 | Completed | Phase 1 | Comparison of Standard Versus Low Bicarbonate Hemodialysis | January 2013 | June 2013 |
| NCT02031770 | Completed | N/A | Metabolic Acidosis and Vascular Function in Patients With Chronic Kidney Disease | January 2014 | March 2016 |
| NCT02098356 | Completed | N/A | Comparison of High Versus Low Bicarbonate Hemodialysis | March 2014 | December 2016 |
| NCT02303548 | Completed | Phase 2 | Bicarbonate in Patients With Out-of-hospital Cardiac Arrest | October 2014 | February 2016 |
| NCT02476253 | Completed | Phase 3 | Sodium Bicarbonate to Treat Severe Acidosis in the Critically Ill | May 5, 2015 | May 29, 2017 |
| NCT02800343 | Completed | Intraoperative Cell Salvage and Postoperative Acidosis | July 8, 2016 | July 31, 2016 | |
| NCT02915601 | Completed | N/A | Bicarbonate Administration in CKD | January 15, 2017 | May 19, 2022 |
| NCT03035812 | Completed | Phase 4 | Alkalinization by Urologists & Nephrologists | February 1, 2017 | February 21, 2020 |
| NCT03317444 | Completed | Phase 3 | Evaluation of TRC101 in Subjects With Metabolic Acidosis Associated With Chronic Kidney Disease | September 26, 2017 | May 15, 2018 |
| NCT03390842 | Completed | Phase 3 | Long-term Safety Extension to Study TRCA-301 | December 20, 2017 | February 22, 2019 |
| NCT03428464 | Completed | N/A | Bicarbonate Administration in Kidney Transplant Recipients | December 5, 2018 | March 25, 2020 |
| NCT04229069 | Completed | N/A | Acid-Base Balance, Metabolism and Minerals | January 3, 2013 | December 30, 2015 |
| NCT04600323 | Completed | Early Phase 1 | Bicarbonate Administration and Cognitive Function in Midlife and Older Adults With CKD | February 1, 2021 | August 30, 2023 |
| NCT04975906 | Completed | The Threshold of Serum Anion Gap as a Screening Tool for Organic Acidosis | July 1, 2017 | June 6, 2023 | |
| NCT05147051 | Completed | Phase 2 | Meglimine Sodium Succinate for Correction of Metabolic Acidosis in Critically Ill Patients | June 16, 2021 | June 22, 2022 |
| NCT05940935 | Completed | The Relationship of Developing Metabolic Acidosis With Antiepleptic Drugs in Craniotomy Operations | May 22, 2023 | August 15, 2023 | |
| NCT05970094 | Completed | N/A | Reduction of Metabolic Acidosis in Patients With Chronic Kidney Disease in Stage 4 and 5 | March 6, 2023 | November 20, 2023 |
| NCT06327737 | Completed | Diabetic Ketoacidosis Diagnosis and Management | December 15, 2020 | March 15, 2023 | |
| NCT06237712 | Enrolling by invitation | N/A | Explorative Study to Investigate the Acid-base Response to Sodium and Potassium Salts in Patients With Chronic Kidney Disease. | January 26, 2024 | July 2026 |
| NCT06366230 | Not yet recruiting | Phase 1/Phase 2 | Adding Urea to the Final Dialysis Fluid | July 1, 2024 | June 30, 2028 |
| NCT05697770 | Recruiting | Phase 3 | SODium BICarbonate for Metabolic Acidosis in the ICU | April 26, 2023 | June 2027 |
| NCT05842369 | Recruiting | N/A | ADVOS® Versus CVVHD in Metabolic or Mixed Acidosis | April 17, 2023 | July 1, 2024 |
| NCT05784389 | Recruiting | N/A | Reduction of Metabolic Acidosis in Patients With Chronic Kidney Disease in Stage 4 and 5 | March 27, 2023 | November 20, 2023 |
| NCT05582824 | Recruiting | Lactate Metabolism in the Hypoperfused Critically Ill | September 15, 2022 | January 2023 | |
| NCT04984226 | Recruiting | Phase 2 | Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD | September 8, 2023 | July 30, 2026 |
| NCT05005793 | Recruiting | Phase 4 | Effect of Alkali Therapy on Vascular and Graft Function in Kidney Transplant Recipients | December 1, 2021 | August 31, 2026 |
| NCT05113641 | Recruiting | Phase 1 | Reducing Dietary Acid With Food Versus Oral Alkali in People With Chronic Kidney Disease (ReDACKD) | August 4, 2023 | December 2025 |
| NCT04727528 | Terminated | Phase 3 | Study of the Effect of SZC on Serum Potassium and Serum Bicarbonate in Patients With Hyperkalemia and Metabolic Acidosis Associated With Chronic Kidney Disease | March 22, 2021 | September 14, 2022 |
| NCT03710291 | Terminated | Phase 3 | Evaluation of Effect of TRC101 on Progression of Chronic Kidney Disease in Subjects With Metabolic Acidosis | November 20, 2018 | September 27, 2022 |
| NCT01894594 | Terminated | Phase 1 | Efficacy, Safety Study and Benefit of Alkali Therapy in Sickle Cell Disease | June 2013 | March 2019 |
| NCT03897101 | Unknown status | Inflammation and Metabolic Acidosis at Birth (AGAIN: AutophaGy AcIdosis Newborn) | March 1, 2019 | December 31, 2020 | |
| NCT01640119 | Unknown status | Phase 3 | Correction of Metabolic Acidosis in End Stage Renal Disease (ESRD) | July 2014 | December 2017 |
| NCT01860001 | Unknown status | Incidence of Postoperative Ketosis and Metabolic Acidosis | October 2012 | August 2013 | |
| NCT05259202 | Unknown status | Value of Fetal Scalp Lactate Sampling During Labour in Cases of Abnormal Fetal Heart Rate | February 1, 2022 | October 31, 2022 | |
| NCT03354507 | Unknown status | N/A | Use of Sodium Bicarbonate in Patients Treated With Topiramate | January 2018 | December 2018 |
| NCT01506258 | Unknown status | N/A | Autologous Stem Cells in Newborns With Oxygen Deprivation | January 2012 | April 2013 |
| NCT03846258 | Withdrawn | Phase 4 | High Versus Low Bicarbonate Bath in Critically-ill Patients Receiving Continuous Renal Replacement Therapy | May 1, 2019 | April 1, 2024 |
- Disase is a (Disease Ontology)
- DOID:0060158
- HPO alt_id (Human Phenotype Ontology)
- HP:0004895
- HPO alt_id (Human Phenotype Ontology)
- HP:0004907
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0001942