chrX:43654907:> Detail (hg38)

Information

Genome

Assembly Position
hg19 chrX:43,514,155-43,606,064 
hg38 chrX:43,654,907-43,746,817

HGVS

Type Transcript Protein
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

[No Data.]

Prediction

[No Data.]

ClinVar

Clinical Significance
Review star [No Data.]
Show details
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score Disease name Description Source Pubmed Links
<0.001 Cardiovascular Diseases In conclusion, this study revealed previously unknown roles of GATA2, Sp1 and TB... BeFree 25810277 Detail
<0.001 child abuse behavior NA BeFree Detail
0.005 Coronary heart disease NA GAD Detail
<0.001 Presenile dementia NA BeFree Detail
0.033 Mental Depression This potentially implicates an MAO-A-sensitive step in advanced breast cancer an... BeFree,GAD 25152370 Detail
0.033 Mental Depression Hypomethylation of MAOA's first exon region in depression: a replication study. BeFree,GAD 25623016 Detail
0.007 depressive disorder This potentially implicates an MAO-A-sensitive step in advanced breast cancer an... BeFree 25152370 Detail
0.007 depressive disorder Hypomethylation of MAOA's first exon region in depression: a replication study. BeFree 25623016 Detail
<0.001 diabetes mellitus NA BeFree Detail
<0.001 Diabetes Mellitus, Non-Insulin-Dependent NA BeFree Detail
0.003 Down syndrome NA LHGDN Detail
0.003 Drug abuse NA BeFree Detail
<0.001 Muscular Dystrophy, Duchenne NA BeFree Detail
<0.001 Dysautonomia, Familial NA BeFree Detail
<0.001 Dyskinetic syndrome NA BeFree Detail
<0.001 dysthymic disorder NA BeFree Detail
<0.001 eclampsia NA BeFree Detail
<0.001 Emotional Disturbances NA BeFree Detail
0.120 endometriosis NA CTD_human Detail
0.002 epilepsy NA GAD Detail
0.003 Epilepsy, Temporal Lobe NA BeFree,GAD Detail
0.002 Fatigue NA GAD Detail
0.007 chronic fatigue syndrome NA GAD Detail
0.006 fibromyalgia NA BeFree,GAD,LHGDN Detail
0.002 gout NA GAD Detail
0.002 Headache NA GAD Detail
0.120 hepatic encephalopathy NA BeFree,CTD_human Detail
0.006 heroin dependence NA BeFree,GAD Detail
0.120 Huntington disease NA CTD_human Detail
0.120 Hypotension NA CTD_human Detail
<0.001 ischemia Molecular mechanism of monoamine oxidase A gene regulation under inflammation an... BeFree 25810277 Detail
<0.001 Acute lymphocytic leukemia NA BeFree Detail
0.033 Mental Depression To investigate the possible relationship between genetic risk factors and depres... BeFree 23157339 Detail
0.007 depressive disorder To investigate the possible relationship between genetic risk factors and depres... BeFree 23157339 Detail
<0.001 Single major depressive episode NA BeFree Detail
0.002 Malignant Carcinoid Syndrome NA GAD Detail
0.003 Mental Retardation NA BeFree,GAD Detail
0.120 myopathy NA CTD_human Detail
<0.001 narcolepsy NA BeFree Detail
0.003 Nausea NA BeFree,GAD Detail
<0.001 Neoplasm Metastasis NA BeFree Detail
0.001 neuroblastoma NA BeFree Detail
<0.001 Melanocytic nevus NA BeFree Detail
0.003 nicotine dependence NA BeFree,GAD Detail
0.009 obesity The gene coding for MAOA contains a 30-bp tandem repeat (uVNTR) polymorphism in ... BeFree,GAD 23761378 Detail
0.007 obsessive-compulsive disorder COMT and MAO-A polymorphisms and obsessive-compulsive disorder: a family-based a... BeFree,GAD 25793616 Detail
<0.001 oppositional defiant disorder NA BeFree Detail
0.001 osteochondritis dissecans NA BeFree Detail
<0.001 Pain NA BeFree Detail
<0.001 Pain, Postoperative NA BeFree Detail
0.022 panic disorder NA BeFree,GAD,LHGDN Detail
0.137 Parkinson disease NA BeFree,CTD_human,GAD Detail
<0.001 Gambling, Pathological NA BeFree Detail
0.010 Personality Disorders NA BeFree,GAD Detail
0.120 pheochromocytoma NA BeFree,CTD_human Detail
0.002 Postoperative Complications NA GAD Detail
0.002 Pregnancy Complications NA GAD Detail
0.122 Prenatal Exposure Delayed Effects NA CTD_human,GAD Detail
<0.001 Prostatic Neoplasms NA BeFree Detail
<0.001 Tension Headache The aim of our study was to investigate a possible association of monoamine oxid... BeFree 25618115 Detail
0.002 Psychoses, Substance-Induced NA GAD Detail
0.003 Psychotic Disorders We have searched for association between 119 SNPs in genes implicated in monoami... BeFree,GAD 25073638 Detail
0.003 restless legs syndrome NA BeFree,GAD Detail
0.035 schizophrenia Expression levels of monoamine oxidase A (MAOA), the enzyme that related to mono... BeFree,GAD,LHGDN 24356376 Detail
<0.001 paranoid schizophrenia NA BeFree Detail
<0.001 Seizures NA BeFree Detail
<0.001 Severe mental retardation (I.Q. 20-34) NA BeFree Detail
0.002 Sex Chromosome Aberrations NA GAD Detail
<0.001 Sleep disturbances NA BeFree Detail
<0.001 Stress, Psychological NA BeFree Detail
<0.001 Cerebrovascular accident NA BeFree Detail
<0.001 substance dependence NA BeFree Detail
<0.001 Substance Use Disorders NA BeFree Detail
0.011 sudden infant death syndrome NA BeFree,GAD,LHGDN Detail
0.003 Gilles de la Tourette syndrome Family-based association study between monoamine oxidase A (MAOA) gene promoter ... BeFree,GAD 24422758 Detail
0.007 Unipolar Depression 94 patients of Caucasian descent with major depressive disorder (f = 61; DSM-IV)... BeFree 24809685 Detail
<0.001 Vascular Diseases NA BeFree Detail
0.002 Violence In summary, these findings support the role of MAOA gene as a prominent genetic ... BeFree 25082653 Detail
0.002 Weight Gain NA GAD Detail
<0.001 Mood swings NA BeFree Detail
<0.001 Photophobia MAOA and TNF-β gene polymorphisms are associated with photophobia but not osmoph... BeFree 26035919 Detail
0.010 Alcohol abuse NA BeFree,GAD Detail
0.003 Depressive Symptoms The assessment of the relationship between personality, the presence of the 5HTT... BeFree 25655492 Detail
<0.001 Panic Attacks NA BeFree Detail
0.003 conduct disorder Results for conduct disorder symptoms did not show a significant relationship be... BeFree 25747527 Detail
0.011 Migraine Disorders MAOA and TNF-β gene polymorphisms are associated with photophobia but not osmoph... BeFree,GAD 26035919 Detail
<0.001 lingual-facial-buccal dyskinesia NA BeFree Detail
<0.001 Secondary malignant neoplasm of lung NA BeFree Detail
<0.001 atypical depressive disorder NA BeFree Detail
<0.001 migraine with aura NA BeFree Detail
<0.001 Malnutrition NA BeFree Detail
<0.001 cholangiocarcinoma NA BeFree Detail
0.002 Depression, Postpartum NA GAD Detail
<0.001 Lesion of brain NA BeFree Detail
<0.001 Emotional disorder With a sample of 228 early-adolescents from a community sample (143 girls) and a... BeFree 25747527 Detail
0.016 Antisocial behavior Candidate genes for aggression and antisocial behavior: a meta-analysis of assoc... BeFree,GAD 24902785 Detail
0.016 Antisocial behavior One of the most studied of these interactions involves low-activity alleles of t... BeFree,GAD 25060544 Detail
0.016 Antisocial behavior Monoamine oxidase A (MAOA) gene promoter region includes a variable number of ta... BeFree,GAD 25142096 Detail
0.016 Antisocial behavior Our results offer the first evidence suggesting epigenetic mechanisms may contri... BeFree,GAD 25497297 Detail
0.012 Personality Traits NA GAD Detail
<0.001 Extrapyramidal sign NA BeFree Detail
<0.001 Pick Disease of the Brain NA BeFree Detail
0.002 Alcohol-Related Disorders NA GAD Detail
0.007 Substance-Related Disorders NA GAD Detail
<0.001 Alcohol or Other Drugs use NA BeFree Detail
0.002 Malignant neoplasm of lung NA GAD Detail
<0.001 Parkinsonian Disorders NA BeFree Detail
0.002 Norrie disease NA BeFree Detail
<0.001 generalized anxiety disorder NA BeFree Detail
<0.001 frontotemporal dementia NA BeFree Detail
<0.001 Common Migraine NA BeFree Detail
<0.001 Manic NA BeFree Detail
<0.001 Mixed anxiety and depressive disorder NA BeFree Detail
<0.001 Familial exudative vitreoretinopathy NA BeFree Detail
<0.001 Nonorganic psychosis NA BeFree Detail
<0.001 Phobic anxiety disorder NA BeFree Detail
0.003 Malignant neoplasm of prostate NA BeFree,GAD Detail
<0.001 Abnormal involuntary movement NA BeFree Detail
0.002 Response to pain finding NA GAD Detail
0.008 dementia NA BeFree,GAD,LHGDN Detail
0.003 Overweight NA BeFree,GAD Detail
<0.001 Premenstrual dysphoric disorder NA BeFree Detail
0.002 Metabolic syndrome X NA GAD Detail
0.017 Mood Disorders Analysis did not show any statistically significant differences in the mean leve... BeFree,GAD,LHGDN 25547397 Detail
<0.001 Alcohol problem The purpose of the present study was to examine whether a cumulative genetic sco... BeFree 24759925 Detail
0.001 Delinquent behavior Functional variants of the MAOA-uVNTR, 5-HTTLPR, and BDNF Val66Met, either alone... BeFree 25522433 Detail
0.002 Sexual abuse Further, the two genotype combinations that differed the most in expression leve... BeFree 25522433 Detail
<0.001 Carcinogenesis NA BeFree Detail
0.001 prostate carcinoma NA BeFree Detail
<0.001 cocaine dependence NA BeFree Detail
<0.001 breast carcinoma The monoamine oxidase-A inhibitor clorgyline promotes a mesenchymal-to-epithelia... BeFree 25152370 Detail
<0.001 Aggressive personality NA BeFree Detail
<0.001 Tardive Dyskinesia NA BeFree Detail
0.001 Central neuroblastoma NA BeFree Detail
<0.001 Dyssomnias NA BeFree Detail
<0.001 cone dystrophy NA BeFree Detail
<0.001 Emotional abuse NA BeFree Detail
<0.001 hyperuricemia NA BeFree Detail
<0.001 Substance abuse problem NA BeFree Detail
<0.001 cardiac event NA BeFree Detail
0.120 End Stage Liver Disease NA CTD_human Detail
<0.001 early pregnancy NA BeFree Detail
0.005 Sleep Disorders NA GAD Detail
<0.001 Completed Suicide NA BeFree Detail
<0.001 Endothelial dysfunction NA BeFree Detail
<0.001 Autistic behavior NA BeFree Detail
0.002 Impulsive aggression Deficient activity of the monoamine oxidase A (MAOA) gene is suggested to contri... BeFree 25497297 Detail
0.002 coronary restenosis NA GAD Detail
0.120 Mental Retardation, X-Linked NA CTD_human Detail
0.033 attention deficit hyperactivity disorder Interactions between MAOA and SYP polymorphisms were associated with symptoms of... BeFree,GAD 25487813 Detail
0.031 major depressive disorder 94 patients of Caucasian descent with major depressive disorder (f = 61; DSM-IV)... BeFree,GAD 24809685 Detail
0.120 Fetal Nutrition Disorders NA CTD_human Detail
<0.001 drug dependence NA BeFree Detail
0.002 Autism Spectrum Disorders However, when the interaction term was omitted, neither MAOA nor FOXP2 was assoc... BeFree 24356376 Detail
0.120 ANTISOCIAL BEHAVIOR FOLLOWING CHILDHOOD MALTREATMENT, SUSCEPTIBILITY TO NA CLINVAR Detail
0.006 MAJOR AFFECTIVE DISORDER 2 NA BeFree,GAD Detail
0.003 NEUROTICISM NA BeFree,GAD Detail
0.004 MAJOR AFFECTIVE DISORDER 1 NA BeFree,GAD Detail
0.002 PANIC DISORDER 1 NA BeFree Detail
<0.001 Transformed migraine NA BeFree Detail
0.004 MAJOR AFFECTIVE DISORDER 4 NA BeFree,GAD Detail
0.004 MAJOR AFFECTIVE DISORDER 5 NA BeFree,GAD Detail
0.004 MAJOR AFFECTIVE DISORDER 6 NA BeFree,GAD Detail
<0.001 Depressive Disorder, Treatment-Resistant NA BeFree Detail
<0.001 liver carcinoma NA BeFree Detail
<0.001 clinical depression NA BeFree Detail
0.004 Major affective disorder 7 NA BeFree,GAD Detail
0.004 MAJOR AFFECTIVE DISORDER 8 NA BeFree,GAD Detail
0.004 MAJOR AFFECTIVE DISORDER 9 NA BeFree,GAD Detail
0.002 Weight Gain Adverse Event NA GAD Detail
<0.001 Nonalcoholic Steatohepatitis NA BeFree Detail
<0.001 Melanocytic nevus of skin NA BeFree Detail
0.003 intellectual disability NA BeFree,LHGDN Detail
<0.001 Adult Antisocial Behavior NA BeFree Detail
<0.001 agoraphobia NA BeFree Detail
0.030 Alcoholic Intoxication, Chronic Meta-analysis of six genes (BDNF, DRD1, DRD3, DRD4, GRIN2B and MAOA) involved in... BeFree,GAD,LHGDN 25660313 Detail
0.011 Alzheimer's disease We investigated the effect of the familial AD APP (Amyloid precursor protein) K6... BeFree,GAD 25841787 Detail
<0.001 Anaplasia NA BeFree Detail
0.003 anorexia nervosa NA BeFree,LHGDN Detail
0.127 antisocial personality disorder Monoamine oxidase A gene promoter methylation and transcriptional downregulation... BeFree,CTD_human,GAD 25497297 Detail
0.009 Anxiety Disorders Furthermore, the analysis of the 30-bp VNTR polymorphism in the MAO A promoter r... BeFree,GAD 25547397 Detail
0.009 Anxiety Disorders Association study of monoamine oxidase-A gene promoter polymorphism (MAOA-uVNTR)... BeFree,GAD 25747527 Detail
<0.001 arteriosclerosis NA BeFree Detail
0.012 As If Personality NA GAD Detail
<0.001 atherosclerosis NA BeFree Detail
0.135 autistic disorder Interaction between MAOA and FOXP2 in association with autism and verbal communi... BeFree,CTD_human,GAD 24356376 Detail
<0.001 Behavior Disorders NA BeFree Detail
0.126 Mental disorders NA BeFree,CTD_human,LHGDN Detail
0.033 bipolar disorder NA BeFree,GAD Detail
0.002 Malignant neoplasm of urinary bladder NA GAD Detail
0.001 Borderline mental retardation (I.Q. 70-85) NA BeFree Detail
0.001 borderline personality disorder NA BeFree Detail
<0.001 Malignant neoplasm of breast The monoamine oxidase-A inhibitor clorgyline promotes a mesenchymal-to-epithelia... BeFree 25152370 Detail
Annotation

Annotations

DescrptionSourceLinks
In conclusion, this study revealed previously unknown roles of GATA2, Sp1 and TBP in modulating MAOA... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
This potentially implicates an MAO-A-sensitive step in advanced breast cancer and should be borne in... DisGeNET Detail
Hypomethylation of MAOA's first exon region in depression: a replication study. DisGeNET Detail
This potentially implicates an MAO-A-sensitive step in advanced breast cancer and should be borne in... DisGeNET Detail
Hypomethylation of MAOA's first exon region in depression: a replication study. DisGeNET Detail
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Molecular mechanism of monoamine oxidase A gene regulation under inflammation and ischemia-like cond... DisGeNET Detail
NA DisGeNET Detail
To investigate the possible relationship between genetic risk factors and depression in AD, we asses... DisGeNET Detail
To investigate the possible relationship between genetic risk factors and depression in AD, we asses... DisGeNET Detail
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The gene coding for MAOA contains a 30-bp tandem repeat (uVNTR) polymorphism in its promoter region ... DisGeNET Detail
COMT and MAO-A polymorphisms and obsessive-compulsive disorder: a family-based association study. DisGeNET Detail
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The aim of our study was to investigate a possible association of monoamine oxidase (MAOA and MAOB) ... DisGeNET Detail
NA DisGeNET Detail
We have searched for association between 119 SNPs in genes implicated in monoaminergic pathways [try... DisGeNET Detail
NA DisGeNET Detail
Expression levels of monoamine oxidase A (MAOA), the enzyme that related to monoamine neurotransmitt... DisGeNET Detail
NA DisGeNET Detail
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Family-based association study between monoamine oxidase A (MAOA) gene promoter VNTR polymorphism an... DisGeNET Detail
94 patients of Caucasian descent with major depressive disorder (f = 61; DSM-IV) were analyzed for D... DisGeNET Detail
NA DisGeNET Detail
In summary, these findings support the role of MAOA gene as a prominent genetic determinant for crim... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
MAOA and TNF-β gene polymorphisms are associated with photophobia but not osmophobia in patients wit... DisGeNET Detail
NA DisGeNET Detail
The assessment of the relationship between personality, the presence of the 5HTT and MAO-A polymorph... DisGeNET Detail
NA DisGeNET Detail
Results for conduct disorder symptoms did not show a significant relationship between the MAOA allel... DisGeNET Detail
MAOA and TNF-β gene polymorphisms are associated with photophobia but not osmophobia in patients wit... DisGeNET Detail
NA DisGeNET Detail
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With a sample of 228 early-adolescents from a community sample (143 girls) and adjusting for environ... DisGeNET Detail
Candidate genes for aggression and antisocial behavior: a meta-analysis of association studies of th... DisGeNET Detail
One of the most studied of these interactions involves low-activity alleles of the monoamine oxidase... DisGeNET Detail
Monoamine oxidase A (MAOA) gene promoter region includes a variable number of tandem repeat (VNTR) a... DisGeNET Detail
Our results offer the first evidence suggesting epigenetic mechanisms may contribute to MAOA dysregu... DisGeNET Detail
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Analysis did not show any statistically significant differences in the mean levels of anxiety, and m... DisGeNET Detail
The purpose of the present study was to examine whether a cumulative genetic score (CGS) containing ... DisGeNET Detail
Functional variants of the MAOA-uVNTR, 5-HTTLPR, and BDNF Val66Met, either alone or in interaction w... DisGeNET Detail
Further, the two genotype combinations that differed the most in expression levels (BDNF Val66Met Va... DisGeNET Detail
NA DisGeNET Detail
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The monoamine oxidase-A inhibitor clorgyline promotes a mesenchymal-to-epithelial transition in the ... DisGeNET Detail
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Deficient activity of the monoamine oxidase A (MAOA) gene is suggested to contribute to serotonergic... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Interactions between MAOA and SYP polymorphisms were associated with symptoms of attention-deficit/h... DisGeNET Detail
94 patients of Caucasian descent with major depressive disorder (f = 61; DSM-IV) were analyzed for D... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
However, when the interaction term was omitted, neither MAOA nor FOXP2 was associated with autism sp... DisGeNET Detail
NA DisGeNET Detail
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Meta-analysis of six genes (BDNF, DRD1, DRD3, DRD4, GRIN2B and MAOA) involved in neuroplasticity and... DisGeNET Detail
We investigated the effect of the familial AD APP (Amyloid precursor protein) K670N/M671L double mut... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Monoamine oxidase A gene promoter methylation and transcriptional downregulation in an offender popu... DisGeNET Detail
Furthermore, the analysis of the 30-bp VNTR polymorphism in the MAO A promoter region demonstrated s... DisGeNET Detail
Association study of monoamine oxidase-A gene promoter polymorphism (MAOA-uVNTR) with self-reported ... DisGeNET Detail
NA DisGeNET Detail
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Interaction between MAOA and FOXP2 in association with autism and verbal communication in a Korean p... DisGeNET Detail
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The monoamine oxidase-A inhibitor clorgyline promotes a mesenchymal-to-epithelial transition in the ... DisGeNET Detail

Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
dbSNP
rs386602118 dbSNP
Genome
hg38
Position
chrX:43,654,907-43,746,817
Variant Type
snv
Genome browser