Annotation Detail
Information
- Associated Genes
- MAOA
- Associated Variants
-
MAOA MUTATION
MAOA MUTATION - Associated Disease
- Alzheimer's disease
- Source Database
- DisGeNET
- Description
- We investigated the effect of the familial AD APP (Amyloid precursor protein) K670N/M671L double mutation, APP Swedish mutation (APPswe), on the expression of 5-HT1B, SERT, MAOA, p11 and 5-HT and its metabolite 5-HIAA in SH-SY5Y human neuroblastoma cell line stably transfected with APPswe mutation.
- Pubmed
- 25841787
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 4
- Original source reporting the Gene Disease association
- BeFree,GAD
- DisGENET score for the Gene Disease association
- 0.0110967791468899
Drugs