chr7:150999023:T>G Detail (hg38) (NOS3)

Information

Genome

Assembly Position
hg19 chr7:150,696,111-150,696,111 View the variant detail on this assembly version.
hg38 chr7:150,999,023-150,999,023

HGVS

Type Transcript Protein
RefSeq NM_000603.4:c.894T>G NP_000594.2:p.Asp298Glu
NM_001160109.1:c.894T>G NP_001153581.1:p.Asp298Glu
NM_001160110.1:c.894T>G NP_001153582.1:p.Asp298Glu
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

JP HGVD:0.919
ToMMo:0.914
NCBN:[No Data.]
NCBN(Hondo):[No Data.]
NCBN(Ryukyu):[No Data.]
East asia ExAC:0.897

Prediction

ClinVar

Clinical Significance Benign
Review star
Show details
Links
Type Database ID Link
Gene MIM 163729 OMIM
HGNC 7876 HGNC
Ensembl ENSG00000164867 Ensembl
NCBI NCBI
Gene Cards Gene Cards
OncoKB OncoKB
Type Database ID Link
Variant TogoVar tgv31480655 TogoVar
COSMIC
MONDO
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
Clinical significance Last evaluated Review status Condition Origin Links
risk factor 2007-04-01 no assertion criteria provided Coronary artery spasm 1, susceptibility to germline Detail
risk factor 2007-04-01 no assertion criteria provided Alzheimer disease, late-onset, susceptibility to germline Detail
risk factor 2007-04-01 no assertion criteria provided Hypertension, pregnancy-induced, susceptibility to germline Detail
Pathogenic 2007-04-01 no assertion criteria provided Hypertension resistant to conventional therapy germline Detail
risk factor 2007-04-01 no assertion criteria provided Ischemic heart disease, susceptibility to germline Detail
risk factor 2007-04-01 no assertion criteria provided Ischemic stroke germline Detail
Benign 2016-03-28 criteria provided, single submitter not specified germline Detail
risk factor 2017-06-01 criteria provided, single submitter Metabolic syndrome, susceptibility to germline Detail
Benign 2021-05-04 criteria provided, single submitter not provided germline Detail
Benign 2021-09-22 criteria provided, single submitter Essential hypertension, genetic,Preeclampsia/eclampsia 1,Ischemic stroke,Alzheimer disease type 1 unknown Detail
Benign 2021-09-22 criteria provided, single submitter Essential hypertension, genetic,Preeclampsia/eclampsia 1,Ischemic stroke,Alzheimer disease type 1 unknown Detail
Benign 2021-09-22 criteria provided, single submitter Essential hypertension, genetic,Preeclampsia/eclampsia 1,Ischemic stroke,Alzheimer disease type 1 unknown Detail
Benign 2021-09-22 criteria provided, single submitter Essential hypertension, genetic,Preeclampsia/eclampsia 1,Ischemic stroke,Alzheimer disease type 1 unknown Detail
CIViC
[No Data.]
DisGeNET
Score Disease name Description Source Pubmed Links
0.347 Hypertensive disease We revealed that a combination of the Arg16Gly and Glu298Asp polymorphisms in AD... BeFree 19373110 Detail
0.203 Hypertensive disease We revealed that a combination of the Arg16Gly and Glu298Asp polymorphisms in AD... BeFree 19373110 Detail
<0.001 Disorder of Achilles tendon A total of 358 unaffected control (CON) participants [159 South Africa (SA CON) ... BeFree 22588838 Detail
<0.001 Disorder of Achilles tendon A total of 358 unaffected control (CON) participants [159 South Africa (SA CON) ... BeFree 22588838 Detail
<0.001 Tendinopathy A total of 358 unaffected control (CON) participants [159 South Africa (SA CON) ... BeFree 22588838 Detail
<0.001 Tendinopathy A total of 358 unaffected control (CON) participants [159 South Africa (SA CON) ... BeFree 22588838 Detail
<0.001 Tendinopathy A total of 358 unaffected control (CON) participants [159 South Africa (SA CON) ... BeFree 22588838 Detail
0.001 vascular disease occlusive All subjects were genotyped for 13 polymorphic variants in the genes of xenobiot... BeFree 23107763 Detail
0.001 ABLEPHARON-MACROSTOMIA SYNDROME Heart rate (HR) was found to be significantly associated with the eNOS3 SNP (rs1... BeFree 22729570 Detail
0.337 hyperhomocysteinemia All subjects were genotyped for 13 polymorphic variants in the genes of xenobiot... BeFree 23107763 Detail
<0.001 hyperhomocysteinemia All subjects were genotyped for 13 polymorphic variants in the genes of xenobiot... BeFree 23107763 Detail
0.003 Sensorineural Hearing Loss (disorder) Multiple logistic regression was used to calculate odds ratios (ORs) for SSNHL a... BeFree 23560644 Detail
<0.001 Sensorineural Hearing Loss (disorder) Multiple logistic regression was used to calculate odds ratios (ORs) for SSNHL a... BeFree 23560644 Detail
<0.001 Sensorineural Hearing Loss (disorder) Multiple logistic regression was used to calculate odds ratios (ORs) for SSNHL a... BeFree 23560644 Detail
0.146 Homocysteinemia All subjects were genotyped for 13 polymorphic variants in the genes of xenobiot... BeFree 23107763 Detail
<0.001 Homocysteinemia All subjects were genotyped for 13 polymorphic variants in the genes of xenobiot... BeFree 23107763 Detail
0.137 Kidney Failure, Chronic In south Indian (SI) subjects there was significant allelic and genotypic associ... BeFree 18413200 Detail
0.002 Chronic Kidney Insufficiency In south Indian (SI) subjects there was significant allelic and genotypic associ... BeFree 18413200 Detail
0.003 Kidney Failure, Chronic In south Indian (SI) subjects there was significant allelic and genotypic associ... BeFree 18413200 Detail
<0.001 Chronic Kidney Insufficiency In south Indian (SI) subjects there was significant allelic and genotypic associ... BeFree 18413200 Detail
0.006 Kidney Failure, Chronic In south Indian (SI) subjects there was significant allelic and genotypic associ... BeFree 18413200 Detail
0.003 gastroschisis In logistic regression, controlling for maternal ethnicity, and using the homozy... BeFree 17051589 Detail
0.003 gastroschisis In logistic regression, controlling for maternal ethnicity, and using the homozy... BeFree 17051589 Detail
0.003 gastroschisis In logistic regression, controlling for maternal ethnicity, and using the homozy... BeFree 17051589 Detail
0.003 gastroschisis In logistic regression, controlling for maternal ethnicity, and using the homozy... BeFree 17051589 Detail
<0.001 Benign Prostatic Hyperplasia The endothelial nitric oxide synthase Glu-298-Asp polymorphism and its mRNA expr... BeFree 16458450 Detail
0.007 Ischemic Cerebrovascular Accident The meta-analysis indicated that eNOS gene 4b/a, T-786C, G894T polymorphism migh... BeFree 23544143 Detail
0.009 Erectile dysfunction In an analysis of ED patients and their genotypes in the GNB3 C825T, the ACE I/D... BeFree 12825146 Detail
0.081 Hypertension, Renovascular We investigated the association of polymorphisms in these genes (the angiotensin... BeFree 15326089 Detail
0.138 coronary artery vasospasm The TT genotype of the single nucleotide polymorphism 894 G/T, located in exon 7... BeFree 12727149 Detail
0.092 Coronary Arteriosclerosis Lack of association between Glu(298) asp polymorphism of endothelial nitric oxid... BeFree 19240311 Detail
0.234 coronary artery disease These findings suggest that the G894T (rs1799983) polymorphism of the eNOS gene ... BeFree 25748584 Detail
0.347 Hypertensive disease To investigate whether the Glu298Asp polymorphism of the eNOS gene affects the i... BeFree 15475025 Detail
<0.001 pneumonia In contrast, NOS3:rs1799983 displayed a protective effect with a 45% reduction i... BeFree 20811626 Detail
0.031 asthma G894T polymorphism of eNOS gene is a predictor of response to combination of inh... BeFree 22966886 Detail
0.234 coronary artery disease Therefore, this study was planned to determine (a) role of endothelium-derived n... BeFree 22045428 Detail
0.006 Diabetes To determine the frequency of eNOS G894T variant and to find the possible associ... BeFree 21602253 Detail
0.189 Cardiovascular Diseases We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males... BeFree 24933031 Detail
0.004 Chronic kidney disease stage 5 The endothelial nitric oxide synthase Glu298Asp and Asp29Asp genotypes were sign... BeFree 15287194 Detail
<0.001 Carcinoma of bladder In this study we analyzed if the NOS3 promoter polymorphism -786T&gt;C (rs207074... BeFree 21703358 Detail
0.120 Hypertension, Renovascular We investigated the association of polymorphisms in these genes (the angiotensin... BeFree 15326089 Detail
0.033 Malignant neoplasm of breast In the current hospital-based case-control study of 421 non-Hispanic white women... BeFree 17063466 Detail
<0.001 Alzheimer Disease, Late Onset Association between NOS3 gene G894T polymorphism and late-onset Alzheimer diseas... BeFree 20505439 Detail
0.144 Metabolic syndrome X The eNOS 894T allele carriers are at greater risk for both MtS and ED, suggestin... BeFree 22304542 Detail
0.004 Chronic kidney disease stage 5 Atherosclerosis and the Glu298Asp polymorphism of the eNOS gene in white patient... BeFree 16364824 Detail
<0.001 Acute mountain sickness Genotype at the missense G894T polymorphism (Glu298Asp) in the NOS3 gene is asso... BeFree 19775216 Detail
0.044 Coronary heart disease The G894T polymorphism on endothelial nitric oxide synthase gene is associated w... BeFree 16038712 Detail
0.011 endometriosis Endothelial nitric oxide synthase gene Glu298Asp polymorphism is associated with... BeFree 19531501 Detail
0.006 Diabetes The objective of this study was to determine the association between eNOS G894T ... BeFree 20642368 Detail
0.134 arteriosclerosis Endothelial nitric oxide synthase gene Glu298Asp polymorphism and blood pressure... BeFree 11905585 Detail
0.003 acute myocardial infarction Few studies were performed on genetics of the renin-angiotensin-aldosterone syst... BeFree 15284679 Detail
<0.001 Cardiovascular Diseases We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males... BeFree 24933031 Detail
0.081 Sepsis Sepsis independently associated with HF, increased NOx, peripheral neutrophils, ... BeFree 25239655 Detail
0.279 Diabetes Mellitus, Non-Insulin-Dependent Impact of the endothelial nitric oxide synthase gene G894T polymorphism on renal... BeFree 18622262 Detail
<0.001 High altitude pulmonary edema In conclusion, ACE rs8066114 and rs4461142 and NOS3 rs1799983 (G894T) polymorphi... BeFree 23603420 Detail
0.014 Endothelial dysfunction Measures of glucose tolerance, insulin sensitivity, markers of endothelial dysfu... BeFree 18349107 Detail
0.284 myocardial infarction Endothelial nitric oxide synthase gene G894T polymorphism and myocardial infarct... BeFree 24498040 Detail
0.008 Cardiovascular Diseases We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males... BeFree 24933031 Detail
0.211 essential hypertension Abstract Background: The G894T (rs1799983) polymorphism in endothelial nitric ox... BeFree 24846690 Detail
0.226 Erectile dysfunction Association of the T-786C, G894T and 4a/4b polymorphisms of the endothelial nitr... BeFree 20955262 Detail
0.003 Impaired cognition The 894G &gt; T (Glu298Asp) variant in the endothelial NOS gene and MTHFR polymo... BeFree 21607713 Detail
0.347 Hypertensive disease Association of endothelial nitric oxide synthase Glu298Asp gene polymorphism in ... BeFree 25811208 Detail
0.201 Sepsis Endothelial (NOS3 E298D) and inducible (NOS2 exon 22) nitric oxide synthase poly... BeFree 25239655 Detail
0.003 azoospermia In this study, the polymorphic distributions of three common polymorphism loci i... BeFree 23756085 Detail
0.003 acute myocardial infarction Few studies were performed on genetics of the renin-angiotensin-aldosterone syst... BeFree 15284679 Detail
0.004 Migraine Disorders Several genetic risk factors have been associated with migraine, but no study ha... BeFree 17115991 Detail
0.027 Coronary heart disease We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males... BeFree 24933031 Detail
0.001 Carcinoma of bladder T-786C, G894T, and intron 4 VNTR (4a/b) polymorphisms of the endothelial nitric ... BeFree 25824737 Detail
0.017 systemic scleroderma We investigated haemorheological variables in patients with idiopathic sudden se... BeFree 17634663 Detail
0.007 Ischemic Cerebrovascular Accident Previous studies have shown that ischemic stroke (IS) was closely associated wit... BeFree 22940147 Detail
0.019 myocardial infarction This study sought to evaluate the effect of genetic polymorphism G894T on endoth... BeFree 16168297 Detail
0.347 Hypertensive disease Endothelial nitric oxide synthase Glu298Asp gene polymorphism, blood pressure an... BeFree 15942458 Detail
0.136 Myocardial Ischemia A recent meta-analysis study found the eNOS G894T polymorphism to be associated ... BeFree 18640391 Detail
0.002 Homocysteinemia These data suggest that both MTHFR C677T and eNOS G894T variants should be regar... BeFree 21607713 Detail
0.008 Hypercholesterolemia The ENOS Glu298Asp polymorphism was associated with hypercholesterolemia (odds r... BeFree 17243909 Detail
<0.001 Hypercholesterolemia, Familial A method to detect the G894T polymorphism of the NOS3 gene. Clinical validation ... BeFree 12113283 Detail
0.020 diabetes mellitus Regarding eNOS G894T gene polymorphisms, 47.4% of the patients had GG (n = 46), ... BeFree 20642368 Detail
0.003 acute myocardial infarction Recent reports have suggested that the Glu298Asp polymorphism in exon 7 of the e... BeFree 12243851 Detail
0.003 fibromyalgia No evidence for an association between the Glu298Asp polymorphism of the endothe... BeFree 16951945 Detail
0.006 Diabetes We analysed the association of the Glu298Asp polymorphism of the endothelial nit... BeFree 18243394 Detail
0.234 coronary artery disease Relationship between hemorheology and Glu(298)Asp polymorphism of endothelial ni... BeFree 19434512 Detail
0.001 aortic aneurysm The current study, in a small group of participants, showed a relationship betwe... BeFree 19638352 Detail
0.005 breast carcinoma This meta-analysis indicated that the eNOS T-786C polymorphism is associated wit... BeFree 25040995 Detail
0.008 brain infarction Homozygosity for the G allele of the Glu298Asp polymorphism in NOS3 was associat... BeFree 10884465 Detail
0.014 Endothelial dysfunction An increasing body of evidence suggests that different genetic factors, such as ... BeFree 17504188 Detail
0.005 prostate carcinoma Effects of the T-786C, G894T, and Intron 4 VNTR (4a/b) polymorphisms of the endo... BeFree 22317880 Detail
0.173 atherosclerosis Relationship between the G894T polymorphism (Glu298Asp variant) in endothelial n... BeFree 11298374 Detail
0.081 Hypertension, Renovascular We investigated the association of polymorphisms in these genes (the angiotensin... BeFree 15326089 Detail
0.014 Endothelial dysfunction Genetic polymorphism G894T on endothelial nitric oxide synthase (eNOS) gene has ... BeFree 16337503 Detail
0.211 essential hypertension Gender specific association of endothelial nitric oxide synthase gene (Glu298Asp... BeFree 18582449 Detail
0.014 Endothelial dysfunction In a population with a compromised endothelial function, concentrations of pheno... BeFree 21816783 Detail
0.040 Acute coronary syndrome Influence of endothelial nitric oxide synthase gene polymorphisms (G894T, 4a4b, ... BeFree 14999203 Detail
0.019 Malignant neoplasm of prostate Endothelial nitric oxide synthase Glu298Asp polymorphism as a risk factor for pr... BeFree 23015399 Detail
0.005 breast carcinoma In conclusion, this meta-analysis suggests that both eNOS E298D and -786T&gt;C p... BeFree 20204503 Detail
<0.001 Cleft lip, isolated The authors genotyped 244 infants with isolated cleft lip with or without cleft ... BeFree 16269583 Detail
0.013 Lupus Erythematosus, Systemic The presented results in this study do not provide support for a major role of e... BeFree 19318399 Detail
<0.001 Malignant neoplasm of urinary bladder In this study we analyzed if the NOS3 promoter polymorphism -786T&gt;C (rs207074... BeFree 21703358 Detail
0.138 coronary artery vasospasm Recently, a Glu298Asp variant of the endothelial nitric oxide synthase gene (NOS... BeFree 11745998 Detail
0.044 Coronary heart disease Polymorphisms of the endothelial nitric oxide synthase (eNOS) gene are associate... BeFree 21793305 Detail
0.138 coronary artery vasospasm The Glu298Asp polymorphism in the endothelial nitric oxide synthase gene is stro... BeFree 12826928 Detail
<0.001 pneumonia In contrast, NOS3:rs1799983 displayed a protective effect with a 45% reduction i... BeFree 20811626 Detail
0.003 Malignant neoplasm of urinary bladder Possible relation between the NOS3 gene GLU298ASP polymorphism and bladder cance... BeFree 23621215 Detail
0.019 Malignant neoplasm of prostate This meta-analysis showed the evidence that NOS3 rs1799983 polymorphism was asso... BeFree 24756758 Detail
0.226 Erectile dysfunction Association analysis of endothelial nitric oxide synthase G894T gene polymorphis... BeFree 19968769 Detail
0.019 Malignant neoplasm of prostate The Glu298Asp polymorphism in the NOS3 gene and the risk of prostate cancer. BeFree 24577889 Detail
<0.001 Septicemia Sepsis independently associated with HF, increased NOx, peripheral neutrophils, ... BeFree 25239655 Detail
0.128 Heart failure Endothelial nitric oxide synthase (eNOS) Glu298Asp single nucleotide polymorphis... BeFree 25612295 Detail
0.015 Ischemic stroke Screening of the NOS3 gene identifies the variants 894G/T, 1998C/G and 2479G/A t... BeFree 24986538 Detail
0.028 Kidney Diseases The G894T polymorphism of the eNOS gene is associated with severity of renal dis... BeFree 19376104 Detail
0.005 Coronary heart disease We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males... BeFree 24933031 Detail
<0.001 gestational diabetes The association of endothelial nitric oxide synthase gene G894T polymorphism and... BeFree 24403014 Detail
0.017 systemic scleroderma Our results indicate that eNOS (G894T) and p22(phox) (C242T) polymorphisms do no... BeFree 15530459 Detail
0.028 Kidney Diseases Endothelial nitric oxide synthase (eNOS) Glu298Asp single nucleotide polymorphis... BeFree 25612295 Detail
0.015 Ischemic stroke An interaction between the E298D and T-786C polymorphisms in NOS3, cigarette smo... BeFree 17108813 Detail
0.002 atherosclerosis We investigated associations between the NOS3 Glu298Asp SNP (rs1799983) and hype... BeFree 19960019 Detail
0.347 Hypertensive disease We studied the association between the Glu298Asp polymorphism of the NO producin... BeFree 11905585 Detail
0.234 coronary artery disease The polymorphism Glu298Asp of endothelial nitric oxide (eNOS) gene has been asso... BeFree 20083095 Detail
0.010 Hypercholesterolemia The ENOS Glu298Asp polymorphism was associated with hypercholesterolemia (odds r... BeFree 17243909 Detail
0.015 Ischemic stroke Glu298Asp polymorphism of the endothelial nitric oxide synthase gene in Turkish ... BeFree 18781402 Detail
0.126 Sepsis Endothelial (NOS3 E298D) and inducible (NOS2 exon 22) nitric oxide synthase poly... BeFree 25239655 Detail
0.003 Metabolic syndrome X We found that genotype Met/Met of the Val66Met polymorphism of the brain-derived... BeFree 20163778 Detail
0.007 High altitude pulmonary edema Association of endothelial nitric oxide synthase (eNOS) G894T polymorphism with ... BeFree 22795910 Detail
0.092 Coronary Arteriosclerosis Association between the endothelial nitric oxide synthase gene Glu298Asp polymor... BeFree 23443250 Detail
0.092 Coronary Arteriosclerosis The G894T polymorphism in the eNOS gene might influence coronary atherosclerosis... BeFree 21114134 Detail
0.234 coronary artery disease Endothelial nitric oxide synthase gene Glu298Asp polymorphism in patients with c... BeFree 20103956 Detail
0.020 diabetes mellitus We analysed the association of the Glu298Asp polymorphism of the endothelial nit... BeFree 18243394 Detail
0.002 Chronic Kidney Insufficiency However, we found that eNOS G894T polymorphism was associated with the presence ... BeFree 19376104 Detail
0.001 Spastic Endothelial nitric oxide synthase gene polymorphism (Glu298Asp) in patients with... BeFree 15778808 Detail
0.044 Coronary heart disease A missense mutation of the nitric oxide synthase (eNOS) gene (Glu298Asp) in five... BeFree 10451235 Detail
0.011 colorectal cancer The effects of NOS3 Glu298Asp variant on colorectal cancer risk and progression ... BeFree 21706163 Detail
0.005 prostate carcinoma This meta-analysis showed the evidence that NOS3 rs1799983 polymorphism was asso... BeFree 24756758 Detail
0.040 Acute coronary syndrome Six polymorphisms (rs1799983, rs2070744, rs1800783, rs3087459, rs1800541, and rs... BeFree 24035903 Detail
0.007 Ischemic Cerebrovascular Accident Endothelial nitric oxide (eNOS) gene G894T and VNTR polymorphisms are closely as... BeFree 24573998 Detail
0.211 essential hypertension ENOS-G894T polymorphism is a risk factor for essential hypertension in China. BeFree 21793305 Detail
0.347 Hypertensive disease Recently, a G894T polymorphism in exon 7 of the eNOS gene has been reported to b... BeFree 18164968 Detail
0.003 Bacteremia Endothelial nitric oxide synthase G894T (GLU298ASP) polymorphism is associated w... BeFree 18827745 Detail
<0.001 Presenile dementia NOS3 gene rs1799983 polymorphism and incident dementia in elderly stroke survivo... BeFree 20691505 Detail
0.092 Coronary Arteriosclerosis The T allele of the missense Glu(298)Asp endothelial nitric oxide synthase gene ... BeFree 11755935 Detail
0.189 Cardiovascular Diseases An insertion/deletion (I/D) polymorphism in the gene encoding the ACE and a sing... BeFree 12837457 Detail
0.279 Diabetes Mellitus, Non-Insulin-Dependent ESR1 XbaI and G894T NOS3 polymorphisms may be useful in accessing insulin resist... BeFree 25077953 Detail
0.092 Coronary Arteriosclerosis Relationship between hemorheology and Glu(298)Asp polymorphism of endothelial ni... BeFree 19434512 Detail
0.284 myocardial infarction Association of the missense Glu298Asp variant of the endothelial nitric oxide sy... BeFree 9626827 Detail
0.261 Cardiovascular Diseases An insertion/deletion (I/D) polymorphism in the gene encoding the ACE and a sing... BeFree 12837457 Detail
0.211 essential hypertension Association between a G894T polymorphism of eNOS gene and essential hypertension... BeFree 18164968 Detail
0.226 Erectile dysfunction Neither of the eNOS polymorphisms, G894T or T-786C, was significantly associated... BeFree 21749219 Detail
0.044 Coronary heart disease Association of endothelial nitric oxide synthase gene variant (G894T) with coron... BeFree 21602253 Detail
0.044 Coronary heart disease Relationship between hemorheology and Glu(298)Asp polymorphism of endothelial ni... BeFree 19434512 Detail
0.097 intracranial aneurysm Polymorphism in exon 7 of the endothelial nitric oxide synthase gene G894T seems... BeFree 18046500 Detail
0.284 myocardial infarction The E298D polymorphic variant of eNOS has been associated with myocardial infarc... BeFree 20854685 Detail
0.005 Hypertensive disease We investigated associations between the NOS3 Glu298Asp SNP (rs1799983) and hype... BeFree 19960019 Detail
0.019 Vascular Diseases The 894TT genotype of 894G&gt;T (Glu298Asp, rs1799983), a polymorphic variant of... BeFree 23512673 Detail
0.003 Metabolic syndrome X We found that genotype Met/Met of the Val66Met polymorphism of the brain-derived... BeFree 20163778 Detail
0.211 essential hypertension Endothelial nitric oxide synthase G894T gene polymorphism and essential hyperten... BeFree 21963726 Detail
0.279 Diabetes Mellitus, Non-Insulin-Dependent We studied eNOS polymorphisms in the promoter region (T-786C), in exon 7 (Glu298... BeFree 17306574 Detail
0.096 obesity Regarding the eNOS E298D polymorphism, the frequency of the mutant D allele carr... BeFree 23042814 Detail
0.347 Hypertensive disease The association between endothelial nitric oxide synthase gene G894T polymorphis... BeFree 24846690 Detail
0.005 prostate carcinoma Endothelial nitric oxide synthase Glu298Asp polymorphism as a risk factor for pr... BeFree 23015399 Detail
0.144 Metabolic syndrome X The association of endothelial nitric oxide synthase G894T polymorphism with C-r... BeFree 18640391 Detail
0.234 coronary artery disease Glu298Asp polymorphism of the endothelial nitric oxide synthase (eNOS) gene (NOS... BeFree 21816783 Detail
<0.001 male infertility Of five NOS gene polymorphisms investigated in the present study, we found NOS3 ... BeFree 25517965 Detail
0.173 atherosclerosis Endothelial nitric oxide synthase gene Glu298Asp polymorphism and blood pressure... BeFree 11905585 Detail
0.234 coronary artery disease Lack of association between the Glu298Asp variant of the endothelial nitric oxid... BeFree 11802531 Detail
0.279 Diabetes Mellitus, Non-Insulin-Dependent In addition, a mutation, Glu298Asp, in exon 7 of NOS3 and a 27 bp variable numbe... BeFree 11071967 Detail
<0.001 early pregnancy Our results do not show any influence of the two polymorphisms, VNTR in intron 4... BeFree 18299866 Detail
0.128 Heart failure Endothelial nitric oxide synthase Glu298Asp gene polymorphism in a multi-ethnica... BeFree 20079452 Detail
0.137 Kidney Failure, Chronic Association of endothelial nitric oxide synthase Glu298Asp gene polymorphism wit... BeFree 23464568 Detail
0.007 Ischemic Cerebrovascular Accident An interaction between the E298D and T-786C polymorphisms in NOS3, cigarette smo... BeFree 17108813 Detail
0.137 Kidney Failure, Chronic The endothelial nitric oxide synthase Glu298Asp and Asp29Asp genotypes were sign... BeFree 15287194 Detail
0.246 Coronary heart disease Effects of eNOS rs1799983 and ACE rs4646994 polymorphisms on the therapeutic eff... BeFree 24827774 Detail
0.118 diabetic retinopathy Nitric oxide synthase 3 (NOS3) 4b/a, T-786C and G894T polymorphisms in associati... BeFree 22506535 Detail
0.142 Cerebrovascular accident In order to investigate the influence of genetic factors in childhood stroke, we... BeFree 19372095 Detail
0.284 myocardial infarction We studied two polymorphisms of the NOS3 gene, the VNTR in intron 4 (4VNTR) and ... BeFree 19014005 Detail
0.138 coronary artery vasospasm A missense Glu298Asp variant in the endothelial nitric oxide synthase gene is as... BeFree 9737779 Detail
0.134 arteriosclerosis Relationship between the G894T polymorphism (Glu298Asp variant) in endothelial n... BeFree 11298374 Detail
0.092 Coronary Arteriosclerosis Endothelial nitric oxide synthase Glu298Asp (G894T) gene polymorphism in coronar... BeFree 23153979 Detail
0.044 Coronary heart disease Lack of association between Glu(298) asp polymorphism of endothelial nitric oxid... BeFree 19240311 Detail
0.211 essential hypertension Evidence for the involvement of eNOS single nucleotide polymorphisms in the deve... BeFree 12530931 Detail
0.003 Endothelial dysfunction An increasing body of evidence suggests that different genetic factors, such as ... BeFree 17504188 Detail
<0.001 gestational diabetes The G894T polymorphism of eNOS gene and decreased NO concentration seem to be in... BeFree 24403014 Detail
0.138 coronary artery vasospasm Recently, we reported that a missense Glu298Asp variant in exon 7 of the eNOS ge... BeFree 9626827 Detail
0.189 Cardiovascular Diseases Our results imply that G894T polymorphism of the endothelial nitric oxide syntha... BeFree 15459608 Detail
0.092 Coronary Arteriosclerosis Endothelial nitric oxide synthase gene Glu298Asp polymorphism in patients with c... BeFree 20103956 Detail
0.007 Ischemic Cerebrovascular Accident Screening of the NOS3 gene identifies the variants 894G/T, 1998C/G and 2479G/A t... BeFree 24986538 Detail
0.028 Kidney Diseases The T-786C, Glu298Asp, and 27 bp variable number of tandem repeats (27 bp-VNTR-a... BeFree 19468830 Detail
0.347 Hypertensive disease Studies on the associations between the nitric oxide synthase gene (NOS3) Glu298... BeFree 15505116 Detail
0.004 hyperglycemia Effects of human endothelial gene polymorphisms on cellular responses to hypergl... BeFree 21844127 Detail
0.001 essential hypertension Abstract Background: The G894T (rs1799983) polymorphism in endothelial nitric ox... BeFree 24846690 Detail
0.004 kidney failure In conclusion, the frequent Glu298Asp polymorphism of ENOS is associated with a ... BeFree 11823442 Detail
<0.001 Hypertension in children We studied the correlation between the Glu298Asp polymorphism of the endothelial... BeFree 21144100 Detail
0.189 Cardiovascular Diseases An endothelial nitric oxide synthase (eNOS) gene polymorphism (Glu298Asp) has be... BeFree 12065317 Detail
0.003 Coronary Occlusion A common variant of endothelial nitric oxide synthase (Glu298Asp) is associated ... BeFree 16164743 Detail
0.137 Kidney Failure, Chronic The distribution of C/T alleIes is significantly different between rapid and slo... BeFree 18815450 Detail
0.211 essential hypertension A common variant of the eNOS gene (E298D) is an independent risk factor for left... BeFree 19132956 Detail
0.219 myocardial infarction This study sought to evaluate the effect of genetic polymorphism G894T on endoth... BeFree 16168297 Detail
0.015 Ischemic stroke Endothelial nitric oxide (eNOS) gene G894T and VNTR polymorphisms are closely as... BeFree 24573998 Detail
0.044 Coronary heart disease The T allele of the missense Glu(298)Asp endothelial nitric oxide synthase gene ... BeFree 11755935 Detail
0.044 Coronary heart disease Glu298Asp polymorphism of the endothelial nitric oxide synthase (eNOS) gene (NOS... BeFree 21816783 Detail
0.025 Behcet Syndrome Lack of evidence for association between endothelial nitric oxide synthase gene ... BeFree 16463158 Detail
0.211 essential hypertension Polymorphisms of rs1799983 (G&gt;T) and rs1800780 (A&gt;G) of the eNOS gene asso... BeFree 23613274 Detail
0.020 Erectile dysfunction ACE gene I/D and NOS3 G894T polymorphisms and response to sildenafil in men with... BeFree 12837457 Detail
0.211 essential hypertension Association of the Glu298Asp polymorphism in the endothelial nitric oxide syntha... BeFree 11394896 Detail
0.019 Malignant neoplasm of prostate This meta-analysis indicated that the eNOS T-786C polymorphism is associated wit... BeFree 25040995 Detail
0.004 Chronic kidney disease stage 5 Association of endothelial nitric oxide synthase Glu298Asp polymorphism with end... BeFree 18793530 Detail
0.137 Kidney Failure, Chronic However, we found that eNOS G894T polymorphism was associated with the presence ... BeFree 19376104 Detail
0.211 essential hypertension Association of endothelial nitric oxide synthase gene G894T polymorphism with es... BeFree 16765468 Detail
0.044 Coronary heart disease Endothelial nitric oxide synthase G894T gene polymorphism in Chilean subjects wi... BeFree 16616056 Detail
0.002 Cerebrovascular accident NOS3 gene rs1799983 polymorphism and incident dementia in elderly stroke survivo... BeFree 20691505 Detail
0.015 Ischemic stroke However, it is the interplay of both environmental and common genetic factors [s... BeFree 16787209 Detail
<0.001 dementia NOS3 gene rs1799983 polymorphism and incident dementia in elderly stroke survivo... BeFree 20691505 Detail
0.347 Hypertensive disease Combined effects of endothelial nitric oxide synthase gene polymorphism (G894T) ... BeFree 11710784 Detail
0.284 myocardial infarction The TT genotype of the single nucleotide polymorphism 894 G/T, located in exon 7... BeFree 12727149 Detail
0.347 Hypertensive disease To examine the relationship of three eNOS gene polymorphisms, T-786C (rs2070744)... BeFree 21968727 Detail
0.234 coronary artery disease The G894T polymorphism on endothelial nitric oxide synthase gene is associated w... BeFree 16038712 Detail
0.234 coronary artery disease Both T-786C and G894T polymorphism of endothelial nitric oxide synthase affect i... BeFree 17001225 Detail
0.159 Diabetic Nephropathy The Glu/Glu-genotype of the NOS3 Glu298Asp polymorphism may increase the risk of... BeFree 17101543 Detail
0.044 Coronary heart disease Lack of association between the Glu298Asp variant of the endothelial nitric oxid... BeFree 11802531 Detail
0.002 acute myocardial infarction Few studies were performed on genetics of the renin-angiotensin-aldosterone syst... BeFree 15284679 Detail
0.013 Lupus Erythematosus, Systemic A meta-analysis was conducted on the associations between the 4b/a, G894T, and C... BeFree 22105628 Detail
<0.001 Gingival Diseases Endothelial nitric oxide synthase Glu298Asp gene polymorphism in periodontal dis... BeFree 16881803 Detail
0.003 Diabetic Foot Association of the G894T polymorphism of the endothelial nitric oxide synthase g... BeFree 20642368 Detail
0.226 Erectile dysfunction eNOS gene intron 4 VNTR and exon 7-G894T polymorphisms in Turkish men with erect... BeFree 19473288 Detail
0.009 congestive heart failure Endothelial nitric oxide synthase Glu298Asp gene polymorphism in a multi-ethnica... BeFree 20079452 Detail
0.004 kidney failure However, a link between eNOS Glu298Asp gene polymorphism and ESRD risk was not f... BeFree 23464568 Detail
0.234 coronary artery disease Association of endothelial nitric oxide synthase gene variant (G894T) with coron... BeFree 21602253 Detail
0.347 Hypertensive disease A single nucleotide variant of the angiotensinogene gene (AGT M235T) and endothe... BeFree 17977523 Detail
<0.001 Lesion of brain In 57 consecutive patients, 35% of whom had lesions on brain MRI, the authors fo... BeFree 15985593 Detail
0.033 Malignant neoplasm of breast Lack of association between NOS3 Glu298Asp and breast cancer risk: a case-contro... BeFree 16807677 Detail
<0.001 oligospermia In this study, the polymorphic distributions of three common polymorphism loci i... BeFree 23756085 Detail
0.234 coronary artery disease A missense mutation of the nitric oxide synthase (eNOS) gene (Glu298Asp) in five... BeFree 10451235 Detail
<0.001 Septicemia Endothelial (NOS3 E298D) and inducible (NOS2 exon 22) nitric oxide synthase poly... BeFree 25239655 Detail
0.005 hyperhomocysteinemia Influence of endothelial nitric oxide synthase gene polymorphisms (G894T, 4a4b, ... BeFree 14999203 Detail
0.072 Coronary Arteriosclerosis Effects of eNOS rs1799983 and ACE rs4646994 polymorphisms on the therapeutic eff... BeFree 24827774 Detail
0.005 prostate carcinoma This meta-analysis indicated that the eNOS T-786C polymorphism is associated wit... BeFree 25040995 Detail
0.006 Aneurysm, Ruptured Three eNOS polymorphisms (eNOS 27VNTR, T786C, and G894T) were genotyped in 96 pa... BeFree 21631225 Detail
<0.001 Metabolic Diseases ESR1 XbaI and G894T NOS3 polymorphisms may be useful in accessing insulin resist... BeFree 25077953 Detail
0.007 High altitude pulmonary edema Meta-analysis showed overall association of NOS3 G894T SNP with HAPE risk under ... BeFree 23603420 Detail
0.159 Diabetic Nephropathy To investigate the association of functional single nucleotide polymorphisms (SN... BeFree 23260854 Detail
0.006 Carotid Atherosclerosis In patients on dialysis the risk alleles of G894T and T-786C polymorphisms of th... BeFree 17586410 Detail
0.226 Erectile dysfunction In an analysis of ED patients and their genotypes in the GNB3 C825T, the ACE I/D... BeFree 12825146 Detail
0.003 migraine with aura Endothelial nitric oxide synthase (Glu298Asp) polymorphism is an independent ris... BeFree 17115991 Detail
0.347 Hypertensive disease The polymorphism Glu298Asp of endothelial nitric oxide (eNOS) gene has been asso... BeFree 20083095 Detail
0.100 Subarachnoid Hemorrhage Endothelial nitric oxide synthase gene [G894T] polymorphism as a possible risk f... BeFree 18046500 Detail
<0.001 Pneumonitis In contrast, NOS3:rs1799983 displayed a protective effect with a 45% reduction i... BeFree 20811626 Detail
<0.001 Cleft lip with or without cleft palate The authors genotyped 244 infants with isolated cleft lip with or without cleft ... BeFree 16269583 Detail
0.003 Respiratory Distress Syndrome, Adult Endothelial NOS gene Glu298Asp polymorphism in preterm neonates with respiratory... BeFree 23359565 Detail
0.126 depressive disorder We found that genotype Met/Met of the Val66Met polymorphism of the brain-derived... BeFree 20163778 Detail
<0.001 Cardiovascular Diseases We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males... BeFree 24933031 Detail
0.005 hyperhomocysteinemia The G894T polymorphism of the eNOS gene is associated with the presence of CAD, ... BeFree 16284093 Detail
<0.001 Left Ventricular Hypertrophy Three NOS3 genetic variants, -T786C (rs2070744), eNOS4a/b and +G894T (rs1799983)... BeFree 19132956 Detail
0.092 Coronary Arteriosclerosis The G894T polymorphism on endothelial nitric oxide synthase gene is associated w... BeFree 16038712 Detail
0.440 Hypertensive disease Frequencies of NOS3 G894T, 4b/a and T(-786) --&gt; C, AGT T704C and ACE ins/del ... BeFree 20186148 Detail
0.347 Hypertensive disease We recently identified a missense variant (Glu298Asp) that lies within exon 7 of... BeFree 11354626 Detail
0.207 pulmonary hypertension Endothelial nitric oxide synthase gene polymorphism (Glu298Asp) and acute pulmon... BeFree 21144100 Detail
0.044 Coronary heart disease We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males... BeFree 24933031 Detail
0.044 Coronary heart disease Endothelial nitric oxide synthase gene Glu298Asp polymorphism in patients with c... BeFree 20103956 Detail
<0.001 Coronary heart disease, susceptibility to, 5 Relationship of the Glu298Asp polymorphism of the endothelial nitric oxide synth... BeFree 11579346 Detail
0.007 Restenosis The endothelial nitric oxide synthase (Glu298Asp and -786T&gt;C) gene polymorphi... BeFree 12473258 Detail
<0.001 Septicemia Endothelial (NOS3 E298D) and inducible (NOS2 exon 22) nitric oxide synthase poly... BeFree 25239655 Detail
0.003 Impaired glucose tolerance Endothelial nitric oxide synthase G894T (Glu298Asp) polymorphism was predictive ... BeFree 16919532 Detail
0.092 Coronary Arteriosclerosis Association of endothelial nitric oxide synthase gene variant (G894T) with coron... BeFree 21602253 Detail
<0.001 Sepsis Endothelial (NOS3 E298D) and inducible (NOS2 exon 22) nitric oxide synthase poly... BeFree 25239655 Detail
0.284 myocardial infarction Endothelial nitric oxide synthase (G894T) gene polymorphism in a random sample o... BeFree 22731641 Detail
0.127 hyperglycemia The eNOS G894T polymorphism appears to be predictive of persistent hyperglycemia... BeFree 16919532 Detail
0.096 obesity Effects of NOS3 Glu298Asp polymorphism on hemodynamic reactivity to stress: infl... BeFree 15505116 Detail
0.136 Myocardial Ischemia We analysed the association of the Glu298Asp polymorphism of the endothelial nit... BeFree 18243394 Detail
0.019 Vascular Diseases The Glu298Asp (G894T) polymorphic variant of eNOS has been associated with vascu... BeFree 11298374 Detail
<0.001 Aggressive periodontitis, generalized The present study showed that eNOS Glu298Asp polymorphism is associated with BOP... BeFree 16881803 Detail
0.284 myocardial infarction An endothelial nitric oxide synthase gene (NOS3) polymorphism in exon 7 (G894T),... BeFree 12113283 Detail
<0.001 Endothelial dysfunction An increasing body of evidence suggests that different genetic factors, such as ... BeFree 17504188 Detail
0.002 Sensation Disorders [Susceptibility genes for gentamicin-induced vestibular dysfunction.] GAD 18776599 Detail
0.003 Malignant neoplasm of urinary bladder T-786C, G894T, and intron 4 VNTR (4a/b) polymorphisms of the endothelial nitric ... BeFree 25824737 Detail
0.284 myocardial infarction We have identified a missense variant, Glu298Asp, in exon 7 of the eNOS gene and... BeFree 9674630 Detail
0.015 Ischemic stroke Previous studies have shown that ischemic stroke (IS) was closely associated wit... BeFree 22940147 Detail
0.332 Diabetic Nephropathy To investigate the association of functional single nucleotide polymorphisms (SN... BeFree 23260854 Detail
0.125 Cardiovascular Diseases We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males... BeFree 24933031 Detail
0.146 Homocysteinemia These data suggest that both MTHFR C677T and eNOS G894T variants should be regar... BeFree 21607713 Detail
0.137 Metabolic syndrome X The association of endothelial nitric oxide synthase G894T polymorphism with C-r... BeFree 18640391 Detail
0.044 Coronary heart disease The G894T polymorphism on endothelial nitric oxide synthase gene is associated w... BeFree 22417945 Detail
0.096 obesity Our aim was to evaluate the effects of endothelial nitric oxide synthase (eNOS) ... BeFree 23517789 Detail
0.128 ischemia We conclude that microvascular reactivity, assessed by change in perfusion after... BeFree 19481100 Detail
0.152 Alzheimer's disease Influence of the Glu298Asp polymorphism of NOS3 on age at onset and homocysteine... BeFree 15718036 Detail
0.347 Hypertensive disease In addition, a missense Glu298Asp mutation in exon 7 of the eNOS gene is reporte... BeFree 12701818 Detail
0.044 Coronary heart disease Association of endothelial nitric oxide synthase (eNOS) gene polymorphism (Glu 2... BeFree 24577926 Detail
0.009 congestive heart failure Endothelial nitric oxide synthase (eNOS) Glu298Asp single nucleotide polymorphis... BeFree 25612295 Detail
0.004 kidney failure The distribution of C/T alleIes is significantly different between rapid and slo... BeFree 18815450 Detail
0.005 Endothelial dysfunction An increasing body of evidence suggests that different genetic factors, such as ... BeFree 17504188 Detail
0.005 breast carcinoma Lack of association between NOS3 Glu298Asp and breast cancer risk: a case-contro... BeFree 16807677 Detail
0.189 Cardiovascular Diseases However, we found that eNOS G894T polymorphism was associated with the presence ... BeFree 19376104 Detail
0.092 Coronary Arteriosclerosis Glu298Asp polymorphism of the endothelial nitric oxide synthase (eNOS) gene (NOS... BeFree 21816783 Detail
0.014 Endothelial dysfunction The 894T allele of a G894T polymorphism in the endothelial nitric oxide synthase... BeFree 11668050 Detail
0.234 coronary artery disease Lack of association between Glu(298) asp polymorphism of endothelial nitric oxid... BeFree 19240311 Detail
0.044 Coronary heart disease Association between the endothelial nitric oxide synthase gene Glu298Asp polymor... BeFree 23443250 Detail
0.284 myocardial infarction The Glu298ASP polymorphism of the endothelial nitric oxide synthase gene is asso... BeFree 20083095 Detail
0.234 coronary artery disease Endothelial nitric oxide synthase G894T gene polymorphism in Chilean subjects wi... BeFree 16616056 Detail
0.279 Diabetes Mellitus, Non-Insulin-Dependent We evaluated the association of -786T&gt;C (promoter region), Glu298Asp (Exon 7)... BeFree 18413207 Detail
0.007 Restenosis The Glu298Asp polymorphism in endothelial nitric oxide synthase gene is associat... BeFree 12243851 Detail
0.006 Diabetes Candidate-gene association studies that examined the association between polymor... BeFree 19773668 Detail
0.126 Sepsis The eNOS gene polymorphism at position 894 (G&gt;T, Glu298Asp) resulting in T al... BeFree 18827745 Detail
0.347 Hypertensive disease Glu298Asp polymorphism of the endothelial nitric oxide synthase (eNOS) gene (NOS... BeFree 21816783 Detail
0.020 diabetes mellitus To determine the frequency of eNOS G894T variant and to find the possible associ... BeFree 21602253 Detail
0.011 endometriosis The endothelial nitric oxide synthase Glu298Asp polymorphism is not a risk facto... BeFree 18313829 Detail
<0.001 Metabolic Diseases ESR1 XbaI and G894T NOS3 polymorphisms may be useful in accessing insulin resist... BeFree 25077953 Detail
0.092 Coronary Arteriosclerosis Lack of association of the Glu298Asp polymorphism of endothelial nitric oxide sy... BeFree 12641536 Detail
0.092 Coronary Arteriosclerosis Lack of association between the Glu298Asp variant of the endothelial nitric oxid... BeFree 11802531 Detail
0.127 hyperglycemia Effects of human endothelial gene polymorphisms on cellular responses to hypergl... BeFree 21844127 Detail
0.017 systemic scleroderma High prevalence of polymorphisms of angiotensin-converting enzyme (I/D) and endo... BeFree 12015245 Detail
0.137 Kidney Failure, Chronic Association of endothelial nitric oxide synthase Glu298Asp polymorphism with end... BeFree 18793530 Detail
0.005 prostate carcinoma The endothelial nitric oxide synthase Glu-298-Asp polymorphism and its mRNA expr... BeFree 16458450 Detail
0.003 Impaired cognition The 894G &gt; T (Glu298Asp) variant in the endothelial NOS gene and MTHFR polymo... BeFree 21607713 Detail
0.004 Chronic kidney disease stage 5 In order to test this hypothesis, we genotyped 173 unrelated ADPKD patients from... BeFree 11823442 Detail
0.006 Carotid Atherosclerosis A common variant of endothelial nitric oxide synthase (Glu298Asp) is an independ... BeFree 11239195 Detail
<0.001 Frontotemporal Lobar Degeneration The NOS3 G894T (Glu298Asp) polymorphism is a risk factor for frontotemporal loba... BeFree 19087148 Detail
0.002 Homocysteinemia Influence of endothelial nitric oxide synthase gene polymorphisms (G894T, 4a4b, ... BeFree 14999203 Detail
0.029 Ischemic stroke The eNOS G894T or eNOS 894TT genotypes in combination with the MTHFR 677TT or AC... BeFree 15595935 Detail
0.015 Ischemic Cerebrovascular Accident Previous studies have shown that ischemic stroke (IS) was closely associated wit... BeFree 22940147 Detail
0.003 Respiratory Distress Syndrome, Newborn Endothelial NOS gene Glu298Asp polymorphism in preterm neonates with respiratory... BeFree 23359565 Detail
0.092 Coronary Arteriosclerosis Both T-786C and G894T polymorphism of endothelial nitric oxide synthase affect i... BeFree 17001225 Detail
0.002 Homocysteinemia The G894T polymorphism of the eNOS gene is associated with the presence of CAD, ... BeFree 16284093 Detail
0.120 Alzheimer disease, late-onset, susceptibility to NA CLINVAR Detail
0.044 Coronary heart disease The polymorphism of Glu298Asp eNOS gene in dead cases may be useful for determin... BeFree 16683402 Detail
0.120 Hypertension, pregnancy-induced, susceptibility to NA CLINVAR Detail
0.138 coronary artery vasospasm Genetic risk factors for coronary artery spasm: significance of endothelial nitr... BeFree 10979242 Detail
0.137 Kidney Failure, Chronic Atherosclerosis and the Glu298Asp polymorphism of the eNOS gene in white patient... BeFree 16364824 Detail
0.019 Malignant neoplasm of prostate Effects of the T-786C, G894T, and Intron 4 VNTR (4a/b) polymorphisms of the endo... BeFree 22317880 Detail
0.017 systemic scleroderma High prevalence of polymorphisms of angiotensin-converting enzyme (I/D) and endo... BeFree 12015245 Detail
0.122 Vestibular Diseases [Susceptibility genes for gentamicin-induced vestibular dysfunction.] GAD 18776599 Detail
0.092 Coronary Arteriosclerosis A missense mutation of the nitric oxide synthase (eNOS) gene (Glu298Asp) in five... BeFree 10451235 Detail
0.152 Alzheimer's disease Molecular epidemiologic studies have presented contradictory results concerning ... BeFree 20505439 Detail
0.029 Ischemic stroke Previous studies have shown that ischemic stroke (IS) was closely associated wit... BeFree 22940147 Detail
0.189 Cardiovascular Diseases A single nucleotide polymorphism in the eNOS gene, where thymine (T) replaces gu... BeFree 22689471 Detail
<0.001 male infertility Of five NOS gene polymorphisms investigated in the present study, we found NOS3 ... BeFree 25517965 Detail
0.234 coronary artery disease Endothelial nitric oxide synthase Glu298Asp (G894T) gene polymorphism in coronar... BeFree 23153979 Detail
0.015 Ischemic stroke Endothelial nitric oxide synthase Glu298Asp, 4b/a, and -786T&gt;C gene polymorph... BeFree 19804474 Detail
0.006 hypertrophic cardiomyopathy Endothelial nitric oxide synthase gene polymorphism (Glu298Asp) in patients with... BeFree 15778808 Detail
0.126 male infertility The role of endothelial nitric oxide synthase (eNOS) T-786C, G894T, and 4a/b gen... BeFree 20586099 Detail
0.002 eclampsia The Glu298Asp variant of the endothelial nitric oxide synthase gene is associate... BeFree 16059745 Detail
0.033 Malignant neoplasm of breast In conclusion, this meta-analysis suggests that both eNOS E298D and -786T&gt;C p... BeFree 20204503 Detail
<0.001 Microalbuminuria The association of endothelial nitric oxide synthase gene G894T polymorphism and... BeFree 24403014 Detail
0.001 Carcinoma of bladder Possible relation between the NOS3 gene GLU298ASP polymorphism and bladder cance... BeFree 23621215 Detail
0.226 Erectile dysfunction Glu298Asp endothelial nitric oxide synthase polymorphism is a risk factor for er... BeFree 15292102 Detail
<0.001 Renal vascular disorder We investigated the association of polymorphisms in these genes (the angiotensin... BeFree 15326089 Detail
<0.001 Renal vascular disorder We investigated the association of polymorphisms in these genes (the angiotensin... BeFree 15326089 Detail
<0.001 Pneumonitis In contrast, NOS3:rs1799983 displayed a protective effect with a 45% reduction i... BeFree 20811626 Detail
0.284 myocardial infarction Genetic polymorphisms G894T on the eNOS gene is associated with endothelial func... BeFree 16337503 Detail
0.347 Hypertensive disease We studied eNOS polymorphisms in the promoter region (T-786C), in exon 7 (Glu298... BeFree 17306574 Detail
0.137 Kidney Failure, Chronic In conclusion, the frequent Glu298Asp polymorphism of ENOS is associated with a ... BeFree 11823442 Detail
0.004 Migraine Disorders Association of endothelial nitric oxide synthase gene polymorphisms (894G/T, -78... BeFree 24845269 Detail
0.002 arteriosclerosis We investigated associations between the NOS3 Glu298Asp SNP (rs1799983) and hype... BeFree 19960019 Detail
0.044 Coronary heart disease Endothelial nitric oxide synthase Glu298Asp (G894T) gene polymorphism in coronar... BeFree 23153979 Detail
0.347 Hypertensive disease We compared the frequencies of three eNOS genetic polymorphisms (T-786C, Glu298A... BeFree 19704415 Detail
0.092 Coronary Arteriosclerosis The polymorphism Glu298Asp of endothelial nitric oxide (eNOS) gene has been asso... BeFree 20083095 Detail
0.002 Cardiovascular Diseases It had been proved that the NOS3 polymorphism (rs1799983) was associated with th... BeFree 23922896 Detail
0.284 myocardial infarction Recently, a Glu298Asp variant of the endothelial nitric oxide synthase gene (NOS... BeFree 11745998 Detail
0.234 coronary artery disease Polymorphisms of the endothelial nitric oxide synthase (eNOS) gene are associate... BeFree 21793305 Detail
0.118 diabetic retinopathy The possible association between the endothelial nitric oxide (eNOS) gene T-786C... BeFree 17973941 Detail
0.279 Diabetes Mellitus, Non-Insulin-Dependent Endothelial nitric oxide synthase Glu298Asp (G894T) gene polymorphism in coronar... BeFree 23153979 Detail
0.226 Erectile dysfunction The eNOS 894T allele carriers are at greater risk for both MtS and ED, suggestin... BeFree 22304542 Detail
0.234 coronary artery disease Lack of association of the Glu298Asp polymorphism of endothelial nitric oxide sy... BeFree 12641536 Detail
0.019 Malignant neoplasm of prostate The endothelial nitric oxide synthase Glu-298-Asp polymorphism and its mRNA expr... BeFree 16458450 Detail
0.002 Chronic Kidney Diseases However, we found that eNOS G894T polymorphism was associated with the presence ... BeFree 19376104 Detail
0.019 Vascular Diseases The eNOS gene polymorphism at position 894 (G&gt;T, Glu298Asp) resulting in T al... BeFree 18827745 Detail
0.005 prostate carcinoma The Glu298Asp polymorphism in the NOS3 gene and the risk of prostate cancer. BeFree 24577889 Detail
0.142 Cerebrovascular accident We tested a single nucleotide polymorphism (SNP) in endothelial nitric oxide syn... BeFree 20691505 Detail
0.016 Ischemic stroke The eNOS G894T or eNOS 894TT genotypes in combination with the MTHFR 677TT or AC... BeFree 15595935 Detail
0.025 Behcet Syndrome Endothelial nitric oxide synthase gene Glu298Asp polymorphism is associated with... BeFree 17067432 Detail
0.234 coronary artery disease Association of endothelial nitric oxide synthase (eNOS) gene polymorphism (Glu 2... BeFree 24577926 Detail
<0.001 Infarction, Lacunar We determined the role of 3 potentially functional eNOS polymorphisms (T-786C, i... BeFree 14963277 Detail
0.159 Diabetic Nephropathy Association of endothelial nitric oxide synthase Glu298Asp, 4b/a, and -786T&gt;C... BeFree 18413207 Detail
<0.001 GRN-related frontotemporal dementia The NOS3 G894T (Glu298Asp) polymorphism is a risk factor for frontotemporal loba... BeFree 19087148 Detail
0.008 Heart Diseases Endothelial nitric oxide synthase gene polymorphism (Glu298Asp) and acute pulmon... BeFree 21144100 Detail
0.002 Ischemic stroke However, it is the interplay of both environmental and common genetic factors [s... BeFree 16787209 Detail
0.003 lupus nephritis A meta-analysis was conducted on the associations between the 4b/a, G894T, and C... BeFree 22105628 Detail
0.173 atherosclerosis Conflicting data exists about the possible contribution of the homozygous Asp/As... BeFree 12641536 Detail
0.347 Hypertensive disease Previous studies regarding endothelial nitric oxide synthase (eNOS) Glu298Asp po... BeFree 17594145 Detail
0.006 eclampsia Among these are the angiotensinogen (AGT) gene variant Met235Threo, which has be... BeFree 16059745 Detail
0.044 Coronary heart disease The polymorphism Glu298Asp of endothelial nitric oxide (eNOS) gene has been asso... BeFree 20083095 Detail
<0.001 Renal Artery Stenosis In the hypertensive population referred for coronary and renal angiography, the ... BeFree 19043368 Detail
0.020 Erectile dysfunction In an analysis of ED patients and their genotypes in the GNB3 C825T, the ACE I/D... BeFree 12825146 Detail
0.097 Left Ventricular Hypertrophy A common variant of the eNOS gene (E298D) is an independent risk factor for left... BeFree 19132956 Detail
0.138 coronary artery vasospasm Three polymorphisms, Paraoxonase 1 (PON1) Q192R (C/G), endothelial nitric oxide ... BeFree 21287574 Detail
0.004 Chronic kidney disease stage 5 Association of endothelial nitric oxide synthase Glu298Asp gene polymorphism wit... BeFree 23464568 Detail
0.005 breast carcinoma In the current hospital-based case-control study of 421 non-Hispanic white women... BeFree 17063466 Detail
0.126 male infertility Endothelial nitric oxide synthase (eNOS) T-786C, 4a4b, and G894T polymorphisms a... BeFree 25505202 Detail
0.008 Polycystic Kidney, Autosomal Dominant Modifier effect of the Glu298Asp polymorphism of endothelial nitric oxide syntha... BeFree 18815450 Detail
0.003 Coronary heart disease We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males... BeFree 24933031 Detail
<0.001 Lesion of brain In 57 consecutive patients, 35% of whom had lesions on brain MRI, the authors fo... BeFree 15985593 Detail
0.020 diabetes mellitus Candidate-gene association studies that examined the association between polymor... BeFree 19773668 Detail
0.029 Ischemic stroke However, it is the interplay of both environmental and common genetic factors [s... BeFree 16787209 Detail
0.028 Kidney Diseases Candidate-gene association studies that examined the association between polymor... BeFree 19773668 Detail
0.092 Coronary Arteriosclerosis An endothelial nitric oxide synthase gene (NOS3) polymorphism in exon 7 (G894T),... BeFree 12113283 Detail
0.081 depressive disorder We found that genotype Met/Met of the Val66Met polymorphism of the brain-derived... BeFree 20163778 Detail
0.017 Diabetes Mellitus, Non-Insulin-Dependent ESR1 XbaI and G894T NOS3 polymorphisms may be useful in accessing insulin resist... BeFree 25077953 Detail
0.002 colorectal carcinoma The effects of NOS3 Glu298Asp variant on colorectal cancer risk and progression ... BeFree 21706163 Detail
0.347 Hypertensive disease Frequencies of NOS3 G894T, 4b/a and T(-786) --&gt; C, AGT T704C and ACE ins/del ... BeFree 20186148 Detail
0.092 Coronary Arteriosclerosis The G894T polymorphism on endothelial nitric oxide synthase gene is associated w... BeFree 22417945 Detail
0.007 Ischemic Cerebrovascular Accident Endothelial nitric oxide synthase Glu298Asp, 4b/a, and -786T&gt;C gene polymorph... BeFree 19804474 Detail
0.337 hyperhomocysteinemia These data suggest that both MTHFR C677T and eNOS G894T variants should be regar... BeFree 21607713 Detail
0.347 Hypertensive disease Association of NOS3 Glu298Asp SNP with hypertension and possible effect modifica... BeFree 19960019 Detail
0.015 Ischemic stroke The meta-analysis indicated that eNOS gene 4b/a, T-786C, G894T polymorphism migh... BeFree 23544143 Detail
0.248 depressive disorder We found that genotype Met/Met of the Val66Met polymorphism of the brain-derived... BeFree 20163778 Detail
0.016 Ischemic stroke However, it is the interplay of both environmental and common genetic factors [s... BeFree 16787209 Detail
0.044 Coronary heart disease Both T-786C and G894T polymorphism of endothelial nitric oxide synthase affect i... BeFree 17001225 Detail
0.211 essential hypertension Prevalence of endothelial nitric oxide synthase E298D polymorphism in Turkish pa... BeFree 23517789 Detail
0.159 Diabetic Nephropathy Association between endothelial nitric oxide synthase Glu298Asp gene polymorphis... BeFree 23113598 Detail
0.092 Coronary Arteriosclerosis Endothelial nitric oxide synthase G894T gene polymorphism in Chilean subjects wi... BeFree 16616056 Detail
0.003 Periodontal Diseases Endothelial nitric oxide synthase Glu298Asp gene polymorphism in periodontal dis... BeFree 16881803 Detail
0.347 Hypertensive disease The results of the present study support that homozygosity for +G894T (E298D) in... BeFree 19132956 Detail
0.092 Coronary Arteriosclerosis Polymorphisms of the endothelial nitric oxide synthase (eNOS) gene are associate... BeFree 21793305 Detail
0.005 Coronary heart disease We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males... BeFree 24933031 Detail
<0.001 Septicemia The eNOS gene polymorphism at position 894 (G&gt;T, Glu298Asp) resulting in T al... BeFree 18827745 Detail
0.100 Subarachnoid Hemorrhage [Endothelial nitric oxide synthase tagging single nucleotide polymorphisms and r... GAD 19419976 Detail
0.189 Cardiovascular Diseases A single nucleotide polymorphism G894T within exon 7 of endothelial nitric oxide... BeFree 21623032 Detail
0.284 myocardial infarction In addition, a missense Glu298Asp mutation in exon 7 of the eNOS gene is reporte... BeFree 12701818 Detail
0.003 psoriasis Association of endothelial nitric oxide synthase Glu298Asp gene polymorphism in ... BeFree 25811208 Detail
0.003 Stroke, Lacunar Homozygosity for the G allele of the Glu298Asp polymorphism in NOS3 was associat... BeFree 10884465 Detail
0.019 Vascular Diseases Endothelial nitric oxide synthase (eNOS) G894T polymorphism has been previously ... BeFree 22004707 Detail
0.033 Malignant neoplasm of breast This meta-analysis indicated that the eNOS T-786C polymorphism is associated wit... BeFree 25040995 Detail
0.044 Coronary heart disease Lack of association of the Glu298Asp polymorphism of endothelial nitric oxide sy... BeFree 12641536 Detail
0.001 Septicemia Endothelial (NOS3 E298D) and inducible (NOS2 exon 22) nitric oxide synthase poly... BeFree 25239655 Detail
0.226 Erectile dysfunction The eNOS 894T allele carriers had significantly higher frequencies of ED and hig... BeFree 19515207 Detail
0.020 diabetes mellitus Thus, the present study demonstrates that there is an association of endothelial... BeFree 22110783 Detail
0.001 Spastic We have identified a missense variant, Glu298Asp, in exon 7 of the eNOS gene and... BeFree 9674630 Detail
0.008 Polycystic Kidney, Autosomal Dominant Previously, a glutamic acid to aspartic acid polymorphism at residue 298 (E/D298... BeFree 12500225 Detail
0.211 essential hypertension Several reports suggested association between the T allele of the endothelial ni... BeFree 17935708 Detail
0.007 Ischemic Cerebrovascular Accident Glu298Asp polymorphism of the endothelial nitric oxide synthase gene in Turkish ... BeFree 18781402 Detail
<0.001 Atherosclerotic renal artery stenosis The Asp allele of the eNOS Glu298Asp polymorphism was associated with atheroscle... BeFree 15326089 Detail
<0.001 ABLEPHARON-MACROSTOMIA SYNDROME We tested the hypothesis that haplotypes, as determined by tagSNPs, in NOS3 woul... BeFree 19775216 Detail
0.226 Erectile dysfunction ACE gene I/D and NOS3 G894T polymorphisms and response to sildenafil in men with... BeFree 12837457 Detail
0.120 HYPERTENSION, RESISTANT TO CONVENTIONAL THERAPY NA CLINVAR Detail
0.092 Coronary Arteriosclerosis Association of endothelial nitric oxide synthase (eNOS) gene polymorphism (Glu 2... BeFree 24577926 Detail
0.005 hyperhomocysteinemia These data suggest that both MTHFR C677T and eNOS G894T variants should be regar... BeFree 21607713 Detail
0.008 Restenosis The I/D angiotensin-I converting enzyme gene polymorphism, gene polymorphisms of... BeFree 15795709 Detail
0.138 coronary artery vasospasm Recent reports have suggested that the Glu298Asp polymorphism in exon 7 of the e... BeFree 12243851 Detail
0.144 Metabolic syndrome X NOS3 Glu298Asp polymorphism interacts with virgin olive oil phenols to determine... BeFree 21816783 Detail
0.016 Metabolic syndrome X We found that genotype Met/Met of the Val66Met polymorphism of the brain-derived... BeFree 20163778 Detail
0.279 Diabetes Mellitus, Non-Insulin-Dependent Endothelial nitric oxide synthase gene polymorphism (G894T) and diabetes mellitu... BeFree 22110783 Detail
0.007 Restenosis The I/D angiotensin-I converting enzyme gene polymorphism, gene polymorphisms of... BeFree 15795709 Detail
0.007 Vasospasm, Intracranial [Endothelial nitric oxide synthase tagging single nucleotide polymorphisms and r... GAD 19419976 Detail
Annotation

Annotations

DescrptionSourceLinks
NM_000603.5(NOS3):c.894T>G (p.Asp298Glu) AND Coronary artery spasm 1, susceptibility to ClinVar Detail
NM_000603.5(NOS3):c.894T>G (p.Asp298Glu) AND Alzheimer disease, late-onset, susceptibility to ClinVar Detail
NM_000603.5(NOS3):c.894T>G (p.Asp298Glu) AND Hypertension, pregnancy-induced, susceptibility to ClinVar Detail
NM_000603.5(NOS3):c.894T>G (p.Asp298Glu) AND Hypertension resistant to conventional therapy ClinVar Detail
NM_000603.5(NOS3):c.894T>G (p.Asp298Glu) AND Ischemic heart disease, susceptibility to ClinVar Detail
NM_000603.5(NOS3):c.894T>G (p.Asp298Glu) AND Ischemic stroke ClinVar Detail
NM_000603.5(NOS3):c.894T>G (p.Asp298Glu) AND not specified ClinVar Detail
NM_000603.4(NOS3):c.[774T>C;894T>G] AND Metabolic syndrome, susceptibility to ClinVar Detail
NM_000603.5(NOS3):c.894T>G (p.Asp298Glu) AND not provided ClinVar Detail
NM_000603.5(NOS3):c.894T>G (p.Asp298Glu) AND multiple conditions ClinVar Detail
NM_000603.5(NOS3):c.894T>G (p.Asp298Glu) AND multiple conditions ClinVar Detail
NM_000603.5(NOS3):c.894T>G (p.Asp298Glu) AND multiple conditions ClinVar Detail
NM_000603.5(NOS3):c.894T>G (p.Asp298Glu) AND multiple conditions ClinVar Detail
We revealed that a combination of the Arg16Gly and Glu298Asp polymorphisms in ADRB2 and NOS3, respec... DisGeNET Detail
We revealed that a combination of the Arg16Gly and Glu298Asp polymorphisms in ADRB2 and NOS3, respec... DisGeNET Detail
A total of 358 unaffected control (CON) participants [159 South Africa (SA CON) and 199 Australia (A... DisGeNET Detail
A total of 358 unaffected control (CON) participants [159 South Africa (SA CON) and 199 Australia (A... DisGeNET Detail
A total of 358 unaffected control (CON) participants [159 South Africa (SA CON) and 199 Australia (A... DisGeNET Detail
A total of 358 unaffected control (CON) participants [159 South Africa (SA CON) and 199 Australia (A... DisGeNET Detail
A total of 358 unaffected control (CON) participants [159 South Africa (SA CON) and 199 Australia (A... DisGeNET Detail
All subjects were genotyped for 13 polymorphic variants in the genes of xenobiotics detoxification C... DisGeNET Detail
Heart rate (HR) was found to be significantly associated with the eNOS3 SNP (rs1799983) and arterial... DisGeNET Detail
All subjects were genotyped for 13 polymorphic variants in the genes of xenobiotics detoxification C... DisGeNET Detail
All subjects were genotyped for 13 polymorphic variants in the genes of xenobiotics detoxification C... DisGeNET Detail
Multiple logistic regression was used to calculate odds ratios (ORs) for SSNHL and Ménière's disease... DisGeNET Detail
Multiple logistic regression was used to calculate odds ratios (ORs) for SSNHL and Ménière's disease... DisGeNET Detail
Multiple logistic regression was used to calculate odds ratios (ORs) for SSNHL and Ménière's disease... DisGeNET Detail
All subjects were genotyped for 13 polymorphic variants in the genes of xenobiotics detoxification C... DisGeNET Detail
All subjects were genotyped for 13 polymorphic variants in the genes of xenobiotics detoxification C... DisGeNET Detail
In south Indian (SI) subjects there was significant allelic and genotypic association of the wild-ty... DisGeNET Detail
In south Indian (SI) subjects there was significant allelic and genotypic association of the wild-ty... DisGeNET Detail
In south Indian (SI) subjects there was significant allelic and genotypic association of the wild-ty... DisGeNET Detail
In south Indian (SI) subjects there was significant allelic and genotypic association of the wild-ty... DisGeNET Detail
In south Indian (SI) subjects there was significant allelic and genotypic association of the wild-ty... DisGeNET Detail
In logistic regression, controlling for maternal ethnicity, and using the homozygote wild-type as re... DisGeNET Detail
In logistic regression, controlling for maternal ethnicity, and using the homozygote wild-type as re... DisGeNET Detail
In logistic regression, controlling for maternal ethnicity, and using the homozygote wild-type as re... DisGeNET Detail
In logistic regression, controlling for maternal ethnicity, and using the homozygote wild-type as re... DisGeNET Detail
The endothelial nitric oxide synthase Glu-298-Asp polymorphism and its mRNA expression in the periph... DisGeNET Detail
The meta-analysis indicated that eNOS gene 4b/a, T-786C, G894T polymorphism might be associated with... DisGeNET Detail
In an analysis of ED patients and their genotypes in the GNB3 C825T, the ACE I/D and the NOS3 G894T ... DisGeNET Detail
We investigated the association of polymorphisms in these genes (the angiotensinogen Met235Thr, the ... DisGeNET Detail
The TT genotype of the single nucleotide polymorphism 894 G/T, located in exon 7 of the eNOS gene, w... DisGeNET Detail
Lack of association between Glu(298) asp polymorphism of endothelial nitric oxide synthase (eNOS) ge... DisGeNET Detail
These findings suggest that the G894T (rs1799983) polymorphism of the eNOS gene was associated with ... DisGeNET Detail
To investigate whether the Glu298Asp polymorphism of the eNOS gene affects the incidence of hyperten... DisGeNET Detail
In contrast, NOS3:rs1799983 displayed a protective effect with a 45% reduction in pneumonitis risk (... DisGeNET Detail
G894T polymorphism of eNOS gene is a predictor of response to combination of inhaled corticosteroids... DisGeNET Detail
Therefore, this study was planned to determine (a) role of endothelium-derived nitric oxide (NO) and... DisGeNET Detail
To determine the frequency of eNOS G894T variant and to find the possible association between this p... DisGeNET Detail
We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males 66.1%, 59.5 ± 10.0 ... DisGeNET Detail
The endothelial nitric oxide synthase Glu298Asp and Asp29Asp genotypes were significantly more frequ... DisGeNET Detail
In this study we analyzed if the NOS3 promoter polymorphism -786T&gt;C (rs2070744) and the NOS3 Glu2... DisGeNET Detail
We investigated the association of polymorphisms in these genes (the angiotensinogen Met235Thr, the ... DisGeNET Detail
In the current hospital-based case-control study of 421 non-Hispanic white women with sporadic breas... DisGeNET Detail
Association between NOS3 gene G894T polymorphism and late-onset Alzheimer disease in a sample from I... DisGeNET Detail
The eNOS 894T allele carriers are at greater risk for both MtS and ED, suggesting that eNOS G894T ge... DisGeNET Detail
Atherosclerosis and the Glu298Asp polymorphism of the eNOS gene in white patients with end-stage ren... DisGeNET Detail
Genotype at the missense G894T polymorphism (Glu298Asp) in the NOS3 gene is associated with suscepti... DisGeNET Detail
The G894T polymorphism on endothelial nitric oxide synthase gene is associated with premature corona... DisGeNET Detail
Endothelial nitric oxide synthase gene Glu298Asp polymorphism is associated with advanced stage endo... DisGeNET Detail
The objective of this study was to determine the association between eNOS G894T polymorphisms and di... DisGeNET Detail
Endothelial nitric oxide synthase gene Glu298Asp polymorphism and blood pressure, left ventricular m... DisGeNET Detail
Few studies were performed on genetics of the renin-angiotensin-aldosterone system and the results a... DisGeNET Detail
We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males 66.1%, 59.5 ± 10.0 ... DisGeNET Detail
Sepsis independently associated with HF, increased NOx, peripheral neutrophils, and fibrinogen level... DisGeNET Detail
Impact of the endothelial nitric oxide synthase gene G894T polymorphism on renal endothelial functio... DisGeNET Detail
In conclusion, ACE rs8066114 and rs4461142 and NOS3 rs1799983 (G894T) polymorphisms may be associate... DisGeNET Detail
Measures of glucose tolerance, insulin sensitivity, markers of endothelial dysfunction, forearm vaso... DisGeNET Detail
Endothelial nitric oxide synthase gene G894T polymorphism and myocardial infarction: a meta-analysis... DisGeNET Detail
We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males 66.1%, 59.5 ± 10.0 ... DisGeNET Detail
Abstract Background: The G894T (rs1799983) polymorphism in endothelial nitric oxide synthase (eNOS/N... DisGeNET Detail
Association of the T-786C, G894T and 4a/4b polymorphisms of the endothelial nitric oxide synthase ge... DisGeNET Detail
The 894G &gt; T (Glu298Asp) variant in the endothelial NOS gene and MTHFR polymorphisms influence ho... DisGeNET Detail
Association of endothelial nitric oxide synthase Glu298Asp gene polymorphism in psoriasis cases with... DisGeNET Detail
Endothelial (NOS3 E298D) and inducible (NOS2 exon 22) nitric oxide synthase polymorphisms, as well a... DisGeNET Detail
In this study, the polymorphic distributions of three common polymorphism loci including T-786C, 4A4... DisGeNET Detail
Few studies were performed on genetics of the renin-angiotensin-aldosterone system and the results a... DisGeNET Detail
Several genetic risk factors have been associated with migraine, but no study has unraveled a possib... DisGeNET Detail
We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males 66.1%, 59.5 ± 10.0 ... DisGeNET Detail
T-786C, G894T, and intron 4 VNTR (4a/b) polymorphisms of the endothelial nitric oxide synthase gene ... DisGeNET Detail
We investigated haemorheological variables in patients with idiopathic sudden sensorineural hearing ... DisGeNET Detail
Previous studies have shown that ischemic stroke (IS) was closely associated with the Glu298Asp poly... DisGeNET Detail
This study sought to evaluate the effect of genetic polymorphism G894T on endothelial nitric oxide s... DisGeNET Detail
Endothelial nitric oxide synthase Glu298Asp gene polymorphism, blood pressure and hypertension in a ... DisGeNET Detail
A recent meta-analysis study found the eNOS G894T polymorphism to be associated with ischemic heart ... DisGeNET Detail
These data suggest that both MTHFR C677T and eNOS G894T variants should be regarded as genetic risk ... DisGeNET Detail
The ENOS Glu298Asp polymorphism was associated with hypercholesterolemia (odds ratio 0.658, 95%CI 0.... DisGeNET Detail
A method to detect the G894T polymorphism of the NOS3 gene. Clinical validation in familial hypercho... DisGeNET Detail
Regarding eNOS G894T gene polymorphisms, 47.4% of the patients had GG (n = 46), 47.4% (n = 46) had G... DisGeNET Detail
Recent reports have suggested that the Glu298Asp polymorphism in exon 7 of the endothelial nitric ox... DisGeNET Detail
No evidence for an association between the Glu298Asp polymorphism of the endothelial nitric oxide sy... DisGeNET Detail
We analysed the association of the Glu298Asp polymorphism of the endothelial nitric oxide synthase (... DisGeNET Detail
Relationship between hemorheology and Glu(298)Asp polymorphism of endothelial nitric oxide synthase ... DisGeNET Detail
The current study, in a small group of participants, showed a relationship between eNOS G894T polymo... DisGeNET Detail
This meta-analysis indicated that the eNOS T-786C polymorphism is associated with elevated cancer ri... DisGeNET Detail
Homozygosity for the G allele of the Glu298Asp polymorphism in NOS3 was associated with BI, and espe... DisGeNET Detail
An increasing body of evidence suggests that different genetic factors, such as angiotensin-converti... DisGeNET Detail
Effects of the T-786C, G894T, and Intron 4 VNTR (4a/b) polymorphisms of the endothelial nitric oxide... DisGeNET Detail
Relationship between the G894T polymorphism (Glu298Asp variant) in endothelial nitric oxide synthase... DisGeNET Detail
We investigated the association of polymorphisms in these genes (the angiotensinogen Met235Thr, the ... DisGeNET Detail
Genetic polymorphism G894T on endothelial nitric oxide synthase (eNOS) gene has been associated with... DisGeNET Detail
Gender specific association of endothelial nitric oxide synthase gene (Glu298Asp) polymorphism with ... DisGeNET Detail
In a population with a compromised endothelial function, concentrations of phenols in dietary VOO in... DisGeNET Detail
Influence of endothelial nitric oxide synthase gene polymorphisms (G894T, 4a4b, T-786C) and hyperhom... DisGeNET Detail
Endothelial nitric oxide synthase Glu298Asp polymorphism as a risk factor for prostate cancer. DisGeNET Detail
In conclusion, this meta-analysis suggests that both eNOS E298D and -786T&gt;C polymorphisms are ass... DisGeNET Detail
The authors genotyped 244 infants with isolated cleft lip with or without cleft palate (CL/P), 99 wi... DisGeNET Detail
The presented results in this study do not provide support for a major role of eNOS Glu298Asp neithe... DisGeNET Detail
In this study we analyzed if the NOS3 promoter polymorphism -786T&gt;C (rs2070744) and the NOS3 Glu2... DisGeNET Detail
Recently, a Glu298Asp variant of the endothelial nitric oxide synthase gene (NOS3) was identified as... DisGeNET Detail
Polymorphisms of the endothelial nitric oxide synthase (eNOS) gene are associated with coronary arte... DisGeNET Detail
The Glu298Asp polymorphism in the endothelial nitric oxide synthase gene is strongly associated with... DisGeNET Detail
In contrast, NOS3:rs1799983 displayed a protective effect with a 45% reduction in pneumonitis risk (... DisGeNET Detail
Possible relation between the NOS3 gene GLU298ASP polymorphism and bladder cancer in Turkey. DisGeNET Detail
This meta-analysis showed the evidence that NOS3 rs1799983 polymorphism was associated with a risk o... DisGeNET Detail
Association analysis of endothelial nitric oxide synthase G894T gene polymorphism and erectile dysfu... DisGeNET Detail
The Glu298Asp polymorphism in the NOS3 gene and the risk of prostate cancer. DisGeNET Detail
Sepsis independently associated with HF, increased NOx, peripheral neutrophils, and fibrinogen level... DisGeNET Detail
Endothelial nitric oxide synthase (eNOS) Glu298Asp single nucleotide polymorphism (SNP) genotype has... DisGeNET Detail
Screening of the NOS3 gene identifies the variants 894G/T, 1998C/G and 2479G/A to be associated with... DisGeNET Detail
The G894T polymorphism of the eNOS gene is associated with severity of renal disease. DisGeNET Detail
We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males 66.1%, 59.5 ± 10.0 ... DisGeNET Detail
The association of endothelial nitric oxide synthase gene G894T polymorphism and serum nitric oxide ... DisGeNET Detail
Our results indicate that eNOS (G894T) and p22(phox) (C242T) polymorphisms do not influence suscepti... DisGeNET Detail
Endothelial nitric oxide synthase (eNOS) Glu298Asp single nucleotide polymorphism (SNP) genotype has... DisGeNET Detail
An interaction between the E298D and T-786C polymorphisms in NOS3, cigarette smoking, and risk of in... DisGeNET Detail
We investigated associations between the NOS3 Glu298Asp SNP (rs1799983) and hypertension, as well as... DisGeNET Detail
We studied the association between the Glu298Asp polymorphism of the NO producing gene, endothelial ... DisGeNET Detail
The polymorphism Glu298Asp of endothelial nitric oxide (eNOS) gene has been associated with hyperten... DisGeNET Detail
The ENOS Glu298Asp polymorphism was associated with hypercholesterolemia (odds ratio 0.658, 95%CI 0.... DisGeNET Detail
Glu298Asp polymorphism of the endothelial nitric oxide synthase gene in Turkish patients with ischem... DisGeNET Detail
Endothelial (NOS3 E298D) and inducible (NOS2 exon 22) nitric oxide synthase polymorphisms, as well a... DisGeNET Detail
We found that genotype Met/Met of the Val66Met polymorphism of the brain-derived neurotrophic factor... DisGeNET Detail
Association of endothelial nitric oxide synthase (eNOS) G894T polymorphism with high altitude pulmon... DisGeNET Detail
Association between the endothelial nitric oxide synthase gene Glu298Asp polymorphism and coronary h... DisGeNET Detail
The G894T polymorphism in the eNOS gene might influence coronary atherosclerosis rather than ICAS in... DisGeNET Detail
Endothelial nitric oxide synthase gene Glu298Asp polymorphism in patients with coronary artery disea... DisGeNET Detail
We analysed the association of the Glu298Asp polymorphism of the endothelial nitric oxide synthase (... DisGeNET Detail
However, we found that eNOS G894T polymorphism was associated with the presence and severity of rena... DisGeNET Detail
Endothelial nitric oxide synthase gene polymorphism (Glu298Asp) in patients with coexistent hypertro... DisGeNET Detail
A missense mutation of the nitric oxide synthase (eNOS) gene (Glu298Asp) in five patients with coron... DisGeNET Detail
The effects of NOS3 Glu298Asp variant on colorectal cancer risk and progression in Turkish populatio... DisGeNET Detail
This meta-analysis showed the evidence that NOS3 rs1799983 polymorphism was associated with a risk o... DisGeNET Detail
Six polymorphisms (rs1799983, rs2070744, rs1800783, rs3087459, rs1800541, and rs5369) of eNOS and ED... DisGeNET Detail
Endothelial nitric oxide (eNOS) gene G894T and VNTR polymorphisms are closely associated with the ri... DisGeNET Detail
ENOS-G894T polymorphism is a risk factor for essential hypertension in China. DisGeNET Detail
Recently, a G894T polymorphism in exon 7 of the eNOS gene has been reported to be associated with hi... DisGeNET Detail
Endothelial nitric oxide synthase G894T (GLU298ASP) polymorphism is associated with hypotension in p... DisGeNET Detail
NOS3 gene rs1799983 polymorphism and incident dementia in elderly stroke survivors. DisGeNET Detail
The T allele of the missense Glu(298)Asp endothelial nitric oxide synthase gene polymorphism is asso... DisGeNET Detail
An insertion/deletion (I/D) polymorphism in the gene encoding the ACE and a single nucleotide exchan... DisGeNET Detail
ESR1 XbaI and G894T NOS3 polymorphisms may be useful in accessing insulin resistance and type 2 diab... DisGeNET Detail
Relationship between hemorheology and Glu(298)Asp polymorphism of endothelial nitric oxide synthase ... DisGeNET Detail
Association of the missense Glu298Asp variant of the endothelial nitric oxide synthase gene with myo... DisGeNET Detail
An insertion/deletion (I/D) polymorphism in the gene encoding the ACE and a single nucleotide exchan... DisGeNET Detail
Association between a G894T polymorphism of eNOS gene and essential hypertension in Hani and Yi mino... DisGeNET Detail
Neither of the eNOS polymorphisms, G894T or T-786C, was significantly associated with sexual or erec... DisGeNET Detail
Association of endothelial nitric oxide synthase gene variant (G894T) with coronary artery disease i... DisGeNET Detail
Relationship between hemorheology and Glu(298)Asp polymorphism of endothelial nitric oxide synthase ... DisGeNET Detail
Polymorphism in exon 7 of the endothelial nitric oxide synthase gene G894T seems to be a possible ri... DisGeNET Detail
The E298D polymorphic variant of eNOS has been associated with myocardial infarction (MI), but data ... DisGeNET Detail
We investigated associations between the NOS3 Glu298Asp SNP (rs1799983) and hypertension, as well as... DisGeNET Detail
The 894TT genotype of 894G&gt;T (Glu298Asp, rs1799983), a polymorphic variant of eNOS, has been asso... DisGeNET Detail
We found that genotype Met/Met of the Val66Met polymorphism of the brain-derived neurotrophic factor... DisGeNET Detail
Endothelial nitric oxide synthase G894T gene polymorphism and essential hypertension in the Chinese ... DisGeNET Detail
We studied eNOS polymorphisms in the promoter region (T-786C), in exon 7 (Glu298Asp), and in intron ... DisGeNET Detail
Regarding the eNOS E298D polymorphism, the frequency of the mutant D allele carriage was only observ... DisGeNET Detail
The association between endothelial nitric oxide synthase gene G894T polymorphism and hypertension i... DisGeNET Detail
Endothelial nitric oxide synthase Glu298Asp polymorphism as a risk factor for prostate cancer. DisGeNET Detail
The association of endothelial nitric oxide synthase G894T polymorphism with C-reactive protein leve... DisGeNET Detail
Glu298Asp polymorphism of the endothelial nitric oxide synthase (eNOS) gene (NOS3) has been characte... DisGeNET Detail
Of five NOS gene polymorphisms investigated in the present study, we found NOS3 rs1799983 might caus... DisGeNET Detail
Endothelial nitric oxide synthase gene Glu298Asp polymorphism and blood pressure, left ventricular m... DisGeNET Detail
Lack of association between the Glu298Asp variant of the endothelial nitric oxide synthase gene and ... DisGeNET Detail
In addition, a mutation, Glu298Asp, in exon 7 of NOS3 and a 27 bp variable number tandem repeat (VNT... DisGeNET Detail
Our results do not show any influence of the two polymorphisms, VNTR in intron 4 and Glu298Asp of th... DisGeNET Detail
Endothelial nitric oxide synthase Glu298Asp gene polymorphism in a multi-ethnical population with he... DisGeNET Detail
Association of endothelial nitric oxide synthase Glu298Asp gene polymorphism with the risk of end-st... DisGeNET Detail
An interaction between the E298D and T-786C polymorphisms in NOS3, cigarette smoking, and risk of in... DisGeNET Detail
The endothelial nitric oxide synthase Glu298Asp and Asp29Asp genotypes were significantly more frequ... DisGeNET Detail
Effects of eNOS rs1799983 and ACE rs4646994 polymorphisms on the therapeutic efficacy of salvianolat... DisGeNET Detail
Nitric oxide synthase 3 (NOS3) 4b/a, T-786C and G894T polymorphisms in association with diabetic ret... DisGeNET Detail
In order to investigate the influence of genetic factors in childhood stroke, we compared the distri... DisGeNET Detail
We studied two polymorphisms of the NOS3 gene, the VNTR in intron 4 (4VNTR) and the Glu298Asp polymo... DisGeNET Detail
A missense Glu298Asp variant in the endothelial nitric oxide synthase gene is associated with corona... DisGeNET Detail
Relationship between the G894T polymorphism (Glu298Asp variant) in endothelial nitric oxide synthase... DisGeNET Detail
Endothelial nitric oxide synthase Glu298Asp (G894T) gene polymorphism in coronary artery disease pat... DisGeNET Detail
Lack of association between Glu(298) asp polymorphism of endothelial nitric oxide synthase (eNOS) ge... DisGeNET Detail
Evidence for the involvement of eNOS single nucleotide polymorphisms in the development of essential... DisGeNET Detail
An increasing body of evidence suggests that different genetic factors, such as angiotensin-converti... DisGeNET Detail
The G894T polymorphism of eNOS gene and decreased NO concentration seem to be independent predictors... DisGeNET Detail
Recently, we reported that a missense Glu298Asp variant in exon 7 of the eNOS gene is a possible gen... DisGeNET Detail
Our results imply that G894T polymorphism of the endothelial nitric oxide synthase gene is associate... DisGeNET Detail
Endothelial nitric oxide synthase gene Glu298Asp polymorphism in patients with coronary artery disea... DisGeNET Detail
Screening of the NOS3 gene identifies the variants 894G/T, 1998C/G and 2479G/A to be associated with... DisGeNET Detail
The T-786C, Glu298Asp, and 27 bp variable number of tandem repeats (27 bp-VNTR-a/b) polymorphsims of... DisGeNET Detail
Studies on the associations between the nitric oxide synthase gene (NOS3) Glu298Asp polymorphism and... DisGeNET Detail
Effects of human endothelial gene polymorphisms on cellular responses to hyperglycaemia: role of NOS... DisGeNET Detail
Abstract Background: The G894T (rs1799983) polymorphism in endothelial nitric oxide synthase (eNOS/N... DisGeNET Detail
In conclusion, the frequent Glu298Asp polymorphism of ENOS is associated with a 5 year lower mean ag... DisGeNET Detail
We studied the correlation between the Glu298Asp polymorphism of the endothelial nitric oxide syntha... DisGeNET Detail
An endothelial nitric oxide synthase (eNOS) gene polymorphism (Glu298Asp) has been associated with c... DisGeNET Detail
A common variant of endothelial nitric oxide synthase (Glu298Asp) is associated with collateral deve... DisGeNET Detail
The distribution of C/T alleIes is significantly different between rapid and slow ADPKD progressors ... DisGeNET Detail
A common variant of the eNOS gene (E298D) is an independent risk factor for left ventricular hypertr... DisGeNET Detail
This study sought to evaluate the effect of genetic polymorphism G894T on endothelial nitric oxide s... DisGeNET Detail
Endothelial nitric oxide (eNOS) gene G894T and VNTR polymorphisms are closely associated with the ri... DisGeNET Detail
The T allele of the missense Glu(298)Asp endothelial nitric oxide synthase gene polymorphism is asso... DisGeNET Detail
Glu298Asp polymorphism of the endothelial nitric oxide synthase (eNOS) gene (NOS3) has been characte... DisGeNET Detail
Lack of evidence for association between endothelial nitric oxide synthase gene polymorphism (glu298... DisGeNET Detail
Polymorphisms of rs1799983 (G&gt;T) and rs1800780 (A&gt;G) of the eNOS gene associated with suscepti... DisGeNET Detail
ACE gene I/D and NOS3 G894T polymorphisms and response to sildenafil in men with erectile dysfunctio... DisGeNET Detail
Association of the Glu298Asp polymorphism in the endothelial nitric oxide synthase gene with essenti... DisGeNET Detail
This meta-analysis indicated that the eNOS T-786C polymorphism is associated with elevated cancer ri... DisGeNET Detail
Association of endothelial nitric oxide synthase Glu298Asp polymorphism with end-stage renal disease... DisGeNET Detail
However, we found that eNOS G894T polymorphism was associated with the presence and severity of rena... DisGeNET Detail
Association of endothelial nitric oxide synthase gene G894T polymorphism with essential hypertension... DisGeNET Detail
Endothelial nitric oxide synthase G894T gene polymorphism in Chilean subjects with coronary artery d... DisGeNET Detail
NOS3 gene rs1799983 polymorphism and incident dementia in elderly stroke survivors. DisGeNET Detail
However, it is the interplay of both environmental and common genetic factors [such as the Leiden V,... DisGeNET Detail
NOS3 gene rs1799983 polymorphism and incident dementia in elderly stroke survivors. DisGeNET Detail
Combined effects of endothelial nitric oxide synthase gene polymorphism (G894T) and insulin resistan... DisGeNET Detail
The TT genotype of the single nucleotide polymorphism 894 G/T, located in exon 7 of the eNOS gene, w... DisGeNET Detail
To examine the relationship of three eNOS gene polymorphisms, T-786C (rs2070744), G894T (rs1799983),... DisGeNET Detail
The G894T polymorphism on endothelial nitric oxide synthase gene is associated with premature corona... DisGeNET Detail
Both T-786C and G894T polymorphism of endothelial nitric oxide synthase affect in-vitro endothelium-... DisGeNET Detail
The Glu/Glu-genotype of the NOS3 Glu298Asp polymorphism may increase the risk of developing DN indep... DisGeNET Detail
Lack of association between the Glu298Asp variant of the endothelial nitric oxide synthase gene and ... DisGeNET Detail
Few studies were performed on genetics of the renin-angiotensin-aldosterone system and the results a... DisGeNET Detail
A meta-analysis was conducted on the associations between the 4b/a, G894T, and C786T polymorphisms o... DisGeNET Detail
Endothelial nitric oxide synthase Glu298Asp gene polymorphism in periodontal diseases. DisGeNET Detail
Association of the G894T polymorphism of the endothelial nitric oxide synthase gene with diabetic fo... DisGeNET Detail
eNOS gene intron 4 VNTR and exon 7-G894T polymorphisms in Turkish men with erectile dysfunction: a c... DisGeNET Detail
Endothelial nitric oxide synthase Glu298Asp gene polymorphism in a multi-ethnical population with he... DisGeNET Detail
However, a link between eNOS Glu298Asp gene polymorphism and ESRD risk was not found in Caucasians a... DisGeNET Detail
Association of endothelial nitric oxide synthase gene variant (G894T) with coronary artery disease i... DisGeNET Detail
A single nucleotide variant of the angiotensinogene gene (AGT M235T) and endothelial nitric oxide sy... DisGeNET Detail
In 57 consecutive patients, 35% of whom had lesions on brain MRI, the authors found that genotypes o... DisGeNET Detail
Lack of association between NOS3 Glu298Asp and breast cancer risk: a case-control study. DisGeNET Detail
In this study, the polymorphic distributions of three common polymorphism loci including T-786C, 4A4... DisGeNET Detail
A missense mutation of the nitric oxide synthase (eNOS) gene (Glu298Asp) in five patients with coron... DisGeNET Detail
Endothelial (NOS3 E298D) and inducible (NOS2 exon 22) nitric oxide synthase polymorphisms, as well a... DisGeNET Detail
Influence of endothelial nitric oxide synthase gene polymorphisms (G894T, 4a4b, T-786C) and hyperhom... DisGeNET Detail
Effects of eNOS rs1799983 and ACE rs4646994 polymorphisms on the therapeutic efficacy of salvianolat... DisGeNET Detail
This meta-analysis indicated that the eNOS T-786C polymorphism is associated with elevated cancer ri... DisGeNET Detail
Three eNOS polymorphisms (eNOS 27VNTR, T786C, and G894T) were genotyped in 96 patients with ruptured... DisGeNET Detail
ESR1 XbaI and G894T NOS3 polymorphisms may be useful in accessing insulin resistance and type 2 diab... DisGeNET Detail
Meta-analysis showed overall association of NOS3 G894T SNP with HAPE risk under the allele contrast ... DisGeNET Detail
To investigate the association of functional single nucleotide polymorphisms (SNPs) of the endotheli... DisGeNET Detail
In patients on dialysis the risk alleles of G894T and T-786C polymorphisms of the eNOS gene are asso... DisGeNET Detail
In an analysis of ED patients and their genotypes in the GNB3 C825T, the ACE I/D and the NOS3 G894T ... DisGeNET Detail
Endothelial nitric oxide synthase (Glu298Asp) polymorphism is an independent risk factor for migrain... DisGeNET Detail
The polymorphism Glu298Asp of endothelial nitric oxide (eNOS) gene has been associated with hyperten... DisGeNET Detail
Endothelial nitric oxide synthase gene [G894T] polymorphism as a possible risk factor in aneurysmal ... DisGeNET Detail
In contrast, NOS3:rs1799983 displayed a protective effect with a 45% reduction in pneumonitis risk (... DisGeNET Detail
The authors genotyped 244 infants with isolated cleft lip with or without cleft palate (CL/P), 99 wi... DisGeNET Detail
Endothelial NOS gene Glu298Asp polymorphism in preterm neonates with respiratory distress syndrome. DisGeNET Detail
We found that genotype Met/Met of the Val66Met polymorphism of the brain-derived neurotrophic factor... DisGeNET Detail
We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males 66.1%, 59.5 ± 10.0 ... DisGeNET Detail
The G894T polymorphism of the eNOS gene is associated with the presence of CAD, and in conjunction w... DisGeNET Detail
Three NOS3 genetic variants, -T786C (rs2070744), eNOS4a/b and +G894T (rs1799983), were genotyped in ... DisGeNET Detail
The G894T polymorphism on endothelial nitric oxide synthase gene is associated with premature corona... DisGeNET Detail
Frequencies of NOS3 G894T, 4b/a and T(-786) --&gt; C, AGT T704C and ACE ins/del polymorphisms were s... DisGeNET Detail
We recently identified a missense variant (Glu298Asp) that lies within exon 7 of the endothelial nit... DisGeNET Detail
Endothelial nitric oxide synthase gene polymorphism (Glu298Asp) and acute pulmonary hypertension pos... DisGeNET Detail
We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males 66.1%, 59.5 ± 10.0 ... DisGeNET Detail
Endothelial nitric oxide synthase gene Glu298Asp polymorphism in patients with coronary artery disea... DisGeNET Detail
Relationship of the Glu298Asp polymorphism of the endothelial nitric oxide synthase gene and early-o... DisGeNET Detail
The endothelial nitric oxide synthase (Glu298Asp and -786T&gt;C) gene polymorphisms are associated w... DisGeNET Detail
Endothelial (NOS3 E298D) and inducible (NOS2 exon 22) nitric oxide synthase polymorphisms, as well a... DisGeNET Detail
Endothelial nitric oxide synthase G894T (Glu298Asp) polymorphism was predictive of glycemic status i... DisGeNET Detail
Association of endothelial nitric oxide synthase gene variant (G894T) with coronary artery disease i... DisGeNET Detail
Endothelial (NOS3 E298D) and inducible (NOS2 exon 22) nitric oxide synthase polymorphisms, as well a... DisGeNET Detail
Endothelial nitric oxide synthase (G894T) gene polymorphism in a random sample of the Egyptian popul... DisGeNET Detail
The eNOS G894T polymorphism appears to be predictive of persistent hyperglycemia in Chinese subjects... DisGeNET Detail
Effects of NOS3 Glu298Asp polymorphism on hemodynamic reactivity to stress: influences of ethnicity ... DisGeNET Detail
We analysed the association of the Glu298Asp polymorphism of the endothelial nitric oxide synthase (... DisGeNET Detail
The Glu298Asp (G894T) polymorphic variant of eNOS has been associated with vascular disease, but fun... DisGeNET Detail
The present study showed that eNOS Glu298Asp polymorphism is associated with BOP in GAgP patients. DisGeNET Detail
An endothelial nitric oxide synthase gene (NOS3) polymorphism in exon 7 (G894T), resulting in Glu298... DisGeNET Detail
An increasing body of evidence suggests that different genetic factors, such as angiotensin-converti... DisGeNET Detail
[Susceptibility genes for gentamicin-induced vestibular dysfunction.] DisGeNET Detail
T-786C, G894T, and intron 4 VNTR (4a/b) polymorphisms of the endothelial nitric oxide synthase gene ... DisGeNET Detail
We have identified a missense variant, Glu298Asp, in exon 7 of the eNOS gene and demonstrated that i... DisGeNET Detail
Previous studies have shown that ischemic stroke (IS) was closely associated with the Glu298Asp poly... DisGeNET Detail
To investigate the association of functional single nucleotide polymorphisms (SNPs) of the endotheli... DisGeNET Detail
We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males 66.1%, 59.5 ± 10.0 ... DisGeNET Detail
These data suggest that both MTHFR C677T and eNOS G894T variants should be regarded as genetic risk ... DisGeNET Detail
The association of endothelial nitric oxide synthase G894T polymorphism with C-reactive protein leve... DisGeNET Detail
The G894T polymorphism on endothelial nitric oxide synthase gene is associated with increased corona... DisGeNET Detail
Our aim was to evaluate the effects of endothelial nitric oxide synthase (eNOS) E298D polymorphism i... DisGeNET Detail
We conclude that microvascular reactivity, assessed by change in perfusion after temporary ischemia ... DisGeNET Detail
Influence of the Glu298Asp polymorphism of NOS3 on age at onset and homocysteine levels in AD patien... DisGeNET Detail
In addition, a missense Glu298Asp mutation in exon 7 of the eNOS gene is reported to be a risk facto... DisGeNET Detail
Association of endothelial nitric oxide synthase (eNOS) gene polymorphism (Glu 298 Asp) with coronar... DisGeNET Detail
Endothelial nitric oxide synthase (eNOS) Glu298Asp single nucleotide polymorphism (SNP) genotype has... DisGeNET Detail
The distribution of C/T alleIes is significantly different between rapid and slow ADPKD progressors ... DisGeNET Detail
An increasing body of evidence suggests that different genetic factors, such as angiotensin-converti... DisGeNET Detail
Lack of association between NOS3 Glu298Asp and breast cancer risk: a case-control study. DisGeNET Detail
However, we found that eNOS G894T polymorphism was associated with the presence and severity of rena... DisGeNET Detail
Glu298Asp polymorphism of the endothelial nitric oxide synthase (eNOS) gene (NOS3) has been characte... DisGeNET Detail
The 894T allele of a G894T polymorphism in the endothelial nitric oxide synthase (eNOS) gene is asso... DisGeNET Detail
Lack of association between Glu(298) asp polymorphism of endothelial nitric oxide synthase (eNOS) ge... DisGeNET Detail
Association between the endothelial nitric oxide synthase gene Glu298Asp polymorphism and coronary h... DisGeNET Detail
The Glu298ASP polymorphism of the endothelial nitric oxide synthase gene is associated with prematur... DisGeNET Detail
Endothelial nitric oxide synthase G894T gene polymorphism in Chilean subjects with coronary artery d... DisGeNET Detail
We evaluated the association of -786T&gt;C (promoter region), Glu298Asp (Exon 7), and 4b4a (Intron 4... DisGeNET Detail
The Glu298Asp polymorphism in endothelial nitric oxide synthase gene is associated with coronary in-... DisGeNET Detail
Candidate-gene association studies that examined the association between polymorphisms of endothelia... DisGeNET Detail
The eNOS gene polymorphism at position 894 (G&gt;T, Glu298Asp) resulting in T allele has been studie... DisGeNET Detail
Glu298Asp polymorphism of the endothelial nitric oxide synthase (eNOS) gene (NOS3) has been characte... DisGeNET Detail
To determine the frequency of eNOS G894T variant and to find the possible association between this p... DisGeNET Detail
The endothelial nitric oxide synthase Glu298Asp polymorphism is not a risk factor for endometriosis ... DisGeNET Detail
ESR1 XbaI and G894T NOS3 polymorphisms may be useful in accessing insulin resistance and type 2 diab... DisGeNET Detail
Lack of association of the Glu298Asp polymorphism of endothelial nitric oxide synthase with manifest... DisGeNET Detail
Lack of association between the Glu298Asp variant of the endothelial nitric oxide synthase gene and ... DisGeNET Detail
Effects of human endothelial gene polymorphisms on cellular responses to hyperglycaemia: role of NOS... DisGeNET Detail
High prevalence of polymorphisms of angiotensin-converting enzyme (I/D) and endothelial nitric oxide... DisGeNET Detail
Association of endothelial nitric oxide synthase Glu298Asp polymorphism with end-stage renal disease... DisGeNET Detail
The endothelial nitric oxide synthase Glu-298-Asp polymorphism and its mRNA expression in the periph... DisGeNET Detail
The 894G &gt; T (Glu298Asp) variant in the endothelial NOS gene and MTHFR polymorphisms influence ho... DisGeNET Detail
In order to test this hypothesis, we genotyped 173 unrelated ADPKD patients from Belgium and the nor... DisGeNET Detail
A common variant of endothelial nitric oxide synthase (Glu298Asp) is an independent risk factor for ... DisGeNET Detail
The NOS3 G894T (Glu298Asp) polymorphism is a risk factor for frontotemporal lobar degeneration. DisGeNET Detail
Influence of endothelial nitric oxide synthase gene polymorphisms (G894T, 4a4b, T-786C) and hyperhom... DisGeNET Detail
The eNOS G894T or eNOS 894TT genotypes in combination with the MTHFR 677TT or ACE D/D genotype incre... DisGeNET Detail
Previous studies have shown that ischemic stroke (IS) was closely associated with the Glu298Asp poly... DisGeNET Detail
Endothelial NOS gene Glu298Asp polymorphism in preterm neonates with respiratory distress syndrome. DisGeNET Detail
Both T-786C and G894T polymorphism of endothelial nitric oxide synthase affect in-vitro endothelium-... DisGeNET Detail
The G894T polymorphism of the eNOS gene is associated with the presence of CAD, and in conjunction w... DisGeNET Detail
NA DisGeNET Detail
The polymorphism of Glu298Asp eNOS gene in dead cases may be useful for determining the cause of dea... DisGeNET Detail
NA DisGeNET Detail
Genetic risk factors for coronary artery spasm: significance of endothelial nitric oxide synthase ge... DisGeNET Detail
Atherosclerosis and the Glu298Asp polymorphism of the eNOS gene in white patients with end-stage ren... DisGeNET Detail
Effects of the T-786C, G894T, and Intron 4 VNTR (4a/b) polymorphisms of the endothelial nitric oxide... DisGeNET Detail
High prevalence of polymorphisms of angiotensin-converting enzyme (I/D) and endothelial nitric oxide... DisGeNET Detail
[Susceptibility genes for gentamicin-induced vestibular dysfunction.] DisGeNET Detail
A missense mutation of the nitric oxide synthase (eNOS) gene (Glu298Asp) in five patients with coron... DisGeNET Detail
Molecular epidemiologic studies have presented contradictory results concerning a potential role of ... DisGeNET Detail
Previous studies have shown that ischemic stroke (IS) was closely associated with the Glu298Asp poly... DisGeNET Detail
A single nucleotide polymorphism in the eNOS gene, where thymine (T) replaces guanine (G) at positio... DisGeNET Detail
Of five NOS gene polymorphisms investigated in the present study, we found NOS3 rs1799983 might caus... DisGeNET Detail
Endothelial nitric oxide synthase Glu298Asp (G894T) gene polymorphism in coronary artery disease pat... DisGeNET Detail
Endothelial nitric oxide synthase Glu298Asp, 4b/a, and -786T&gt;C gene polymorphisms and the risk of... DisGeNET Detail
Endothelial nitric oxide synthase gene polymorphism (Glu298Asp) in patients with coexistent hypertro... DisGeNET Detail
The role of endothelial nitric oxide synthase (eNOS) T-786C, G894T, and 4a/b gene polymorphisms in t... DisGeNET Detail
The Glu298Asp variant of the endothelial nitric oxide synthase gene is associated with an increased ... DisGeNET Detail
In conclusion, this meta-analysis suggests that both eNOS E298D and -786T&gt;C polymorphisms are ass... DisGeNET Detail
The association of endothelial nitric oxide synthase gene G894T polymorphism and serum nitric oxide ... DisGeNET Detail
Possible relation between the NOS3 gene GLU298ASP polymorphism and bladder cancer in Turkey. DisGeNET Detail
Glu298Asp endothelial nitric oxide synthase polymorphism is a risk factor for erectile dysfunction i... DisGeNET Detail
We investigated the association of polymorphisms in these genes (the angiotensinogen Met235Thr, the ... DisGeNET Detail
We investigated the association of polymorphisms in these genes (the angiotensinogen Met235Thr, the ... DisGeNET Detail
In contrast, NOS3:rs1799983 displayed a protective effect with a 45% reduction in pneumonitis risk (... DisGeNET Detail
Genetic polymorphisms G894T on the eNOS gene is associated with endothelial function and vWF levels ... DisGeNET Detail
We studied eNOS polymorphisms in the promoter region (T-786C), in exon 7 (Glu298Asp), and in intron ... DisGeNET Detail
In conclusion, the frequent Glu298Asp polymorphism of ENOS is associated with a 5 year lower mean ag... DisGeNET Detail
Association of endothelial nitric oxide synthase gene polymorphisms (894G/T, -786T/C, G10T) and clin... DisGeNET Detail
We investigated associations between the NOS3 Glu298Asp SNP (rs1799983) and hypertension, as well as... DisGeNET Detail
Endothelial nitric oxide synthase Glu298Asp (G894T) gene polymorphism in coronary artery disease pat... DisGeNET Detail
We compared the frequencies of three eNOS genetic polymorphisms (T-786C, Glu298Asp and b/a intron 4)... DisGeNET Detail
The polymorphism Glu298Asp of endothelial nitric oxide (eNOS) gene has been associated with hyperten... DisGeNET Detail
It had been proved that the NOS3 polymorphism (rs1799983) was associated with the development of car... DisGeNET Detail
Recently, a Glu298Asp variant of the endothelial nitric oxide synthase gene (NOS3) was identified as... DisGeNET Detail
Polymorphisms of the endothelial nitric oxide synthase (eNOS) gene are associated with coronary arte... DisGeNET Detail
The possible association between the endothelial nitric oxide (eNOS) gene T-786C (promoter region), ... DisGeNET Detail
Endothelial nitric oxide synthase Glu298Asp (G894T) gene polymorphism in coronary artery disease pat... DisGeNET Detail
The eNOS 894T allele carriers are at greater risk for both MtS and ED, suggesting that eNOS G894T ge... DisGeNET Detail
Lack of association of the Glu298Asp polymorphism of endothelial nitric oxide synthase with manifest... DisGeNET Detail
The endothelial nitric oxide synthase Glu-298-Asp polymorphism and its mRNA expression in the periph... DisGeNET Detail
However, we found that eNOS G894T polymorphism was associated with the presence and severity of rena... DisGeNET Detail
The eNOS gene polymorphism at position 894 (G&gt;T, Glu298Asp) resulting in T allele has been studie... DisGeNET Detail
The Glu298Asp polymorphism in the NOS3 gene and the risk of prostate cancer. DisGeNET Detail
We tested a single nucleotide polymorphism (SNP) in endothelial nitric oxide synthase (NOS3) gene at... DisGeNET Detail
The eNOS G894T or eNOS 894TT genotypes in combination with the MTHFR 677TT or ACE D/D genotype incre... DisGeNET Detail
Endothelial nitric oxide synthase gene Glu298Asp polymorphism is associated with Behçet's disease. DisGeNET Detail
Association of endothelial nitric oxide synthase (eNOS) gene polymorphism (Glu 298 Asp) with coronar... DisGeNET Detail
We determined the role of 3 potentially functional eNOS polymorphisms (T-786C, intron 4ab, G894T) lo... DisGeNET Detail
Association of endothelial nitric oxide synthase Glu298Asp, 4b/a, and -786T&gt;C gene variants with ... DisGeNET Detail
The NOS3 G894T (Glu298Asp) polymorphism is a risk factor for frontotemporal lobar degeneration. DisGeNET Detail
Endothelial nitric oxide synthase gene polymorphism (Glu298Asp) and acute pulmonary hypertension pos... DisGeNET Detail
However, it is the interplay of both environmental and common genetic factors [such as the Leiden V,... DisGeNET Detail
A meta-analysis was conducted on the associations between the 4b/a, G894T, and C786T polymorphisms o... DisGeNET Detail
Conflicting data exists about the possible contribution of the homozygous Asp/Asp genotype of the Gl... DisGeNET Detail
Previous studies regarding endothelial nitric oxide synthase (eNOS) Glu298Asp polymorphism focused u... DisGeNET Detail
Among these are the angiotensinogen (AGT) gene variant Met235Threo, which has been associated with p... DisGeNET Detail
The polymorphism Glu298Asp of endothelial nitric oxide (eNOS) gene has been associated with hyperten... DisGeNET Detail
In the hypertensive population referred for coronary and renal angiography, the ACE insertion/deleti... DisGeNET Detail
In an analysis of ED patients and their genotypes in the GNB3 C825T, the ACE I/D and the NOS3 G894T ... DisGeNET Detail
A common variant of the eNOS gene (E298D) is an independent risk factor for left ventricular hypertr... DisGeNET Detail
Three polymorphisms, Paraoxonase 1 (PON1) Q192R (C/G), endothelial nitric oxide synthase (eNOS) E298... DisGeNET Detail
Association of endothelial nitric oxide synthase Glu298Asp gene polymorphism with the risk of end-st... DisGeNET Detail
In the current hospital-based case-control study of 421 non-Hispanic white women with sporadic breas... DisGeNET Detail
Endothelial nitric oxide synthase (eNOS) T-786C, 4a4b, and G894T polymorphisms and male infertility:... DisGeNET Detail
Modifier effect of the Glu298Asp polymorphism of endothelial nitric oxide synthase gene in autosomal... DisGeNET Detail
We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males 66.1%, 59.5 ± 10.0 ... DisGeNET Detail
In 57 consecutive patients, 35% of whom had lesions on brain MRI, the authors found that genotypes o... DisGeNET Detail
Candidate-gene association studies that examined the association between polymorphisms of endothelia... DisGeNET Detail
However, it is the interplay of both environmental and common genetic factors [such as the Leiden V,... DisGeNET Detail
Candidate-gene association studies that examined the association between polymorphisms of endothelia... DisGeNET Detail
An endothelial nitric oxide synthase gene (NOS3) polymorphism in exon 7 (G894T), resulting in Glu298... DisGeNET Detail
We found that genotype Met/Met of the Val66Met polymorphism of the brain-derived neurotrophic factor... DisGeNET Detail
ESR1 XbaI and G894T NOS3 polymorphisms may be useful in accessing insulin resistance and type 2 diab... DisGeNET Detail
The effects of NOS3 Glu298Asp variant on colorectal cancer risk and progression in Turkish populatio... DisGeNET Detail
Frequencies of NOS3 G894T, 4b/a and T(-786) --&gt; C, AGT T704C and ACE ins/del polymorphisms were s... DisGeNET Detail
The G894T polymorphism on endothelial nitric oxide synthase gene is associated with increased corona... DisGeNET Detail
Endothelial nitric oxide synthase Glu298Asp, 4b/a, and -786T&gt;C gene polymorphisms and the risk of... DisGeNET Detail
These data suggest that both MTHFR C677T and eNOS G894T variants should be regarded as genetic risk ... DisGeNET Detail
Association of NOS3 Glu298Asp SNP with hypertension and possible effect modification of dietary fat ... DisGeNET Detail
The meta-analysis indicated that eNOS gene 4b/a, T-786C, G894T polymorphism might be associated with... DisGeNET Detail
We found that genotype Met/Met of the Val66Met polymorphism of the brain-derived neurotrophic factor... DisGeNET Detail
However, it is the interplay of both environmental and common genetic factors [such as the Leiden V,... DisGeNET Detail
Both T-786C and G894T polymorphism of endothelial nitric oxide synthase affect in-vitro endothelium-... DisGeNET Detail
Prevalence of endothelial nitric oxide synthase E298D polymorphism in Turkish patients with essentia... DisGeNET Detail
Association between endothelial nitric oxide synthase Glu298Asp gene polymorphism and diabetic nephr... DisGeNET Detail
Endothelial nitric oxide synthase G894T gene polymorphism in Chilean subjects with coronary artery d... DisGeNET Detail
Endothelial nitric oxide synthase Glu298Asp gene polymorphism in periodontal diseases. DisGeNET Detail
The results of the present study support that homozygosity for +G894T (E298D) in NOS3 is a genetic r... DisGeNET Detail
Polymorphisms of the endothelial nitric oxide synthase (eNOS) gene are associated with coronary arte... DisGeNET Detail
We enrolled 1977 Japanese type 2 diabetic subjects without history of CVD (males 66.1%, 59.5 ± 10.0 ... DisGeNET Detail
The eNOS gene polymorphism at position 894 (G&gt;T, Glu298Asp) resulting in T allele has been studie... DisGeNET Detail
[Endothelial nitric oxide synthase tagging single nucleotide polymorphisms and recovery from aneurys... DisGeNET Detail
A single nucleotide polymorphism G894T within exon 7 of endothelial nitric oxide synthase (eNOS-7) g... DisGeNET Detail
In addition, a missense Glu298Asp mutation in exon 7 of the eNOS gene is reported to be a risk facto... DisGeNET Detail
Association of endothelial nitric oxide synthase Glu298Asp gene polymorphism in psoriasis cases with... DisGeNET Detail
Homozygosity for the G allele of the Glu298Asp polymorphism in NOS3 was associated with BI, and espe... DisGeNET Detail
Endothelial nitric oxide synthase (eNOS) G894T polymorphism has been previously associated with vasc... DisGeNET Detail
This meta-analysis indicated that the eNOS T-786C polymorphism is associated with elevated cancer ri... DisGeNET Detail
Lack of association of the Glu298Asp polymorphism of endothelial nitric oxide synthase with manifest... DisGeNET Detail
Endothelial (NOS3 E298D) and inducible (NOS2 exon 22) nitric oxide synthase polymorphisms, as well a... DisGeNET Detail
The eNOS 894T allele carriers had significantly higher frequencies of ED and higher IPSS, suggesting... DisGeNET Detail
Thus, the present study demonstrates that there is an association of endothelial nitric oxide syntha... DisGeNET Detail
We have identified a missense variant, Glu298Asp, in exon 7 of the eNOS gene and demonstrated that i... DisGeNET Detail
Previously, a glutamic acid to aspartic acid polymorphism at residue 298 (E/D298) of the endothelial... DisGeNET Detail
Several reports suggested association between the T allele of the endothelial nitric oxide synthase ... DisGeNET Detail
Glu298Asp polymorphism of the endothelial nitric oxide synthase gene in Turkish patients with ischem... DisGeNET Detail
The Asp allele of the eNOS Glu298Asp polymorphism was associated with atherosclerotic renal artery s... DisGeNET Detail
We tested the hypothesis that haplotypes, as determined by tagSNPs, in NOS3 would be differentially ... DisGeNET Detail
ACE gene I/D and NOS3 G894T polymorphisms and response to sildenafil in men with erectile dysfunctio... DisGeNET Detail
NA DisGeNET Detail
Association of endothelial nitric oxide synthase (eNOS) gene polymorphism (Glu 298 Asp) with coronar... DisGeNET Detail
These data suggest that both MTHFR C677T and eNOS G894T variants should be regarded as genetic risk ... DisGeNET Detail
The I/D angiotensin-I converting enzyme gene polymorphism, gene polymorphisms of the endothelial nit... DisGeNET Detail
Recent reports have suggested that the Glu298Asp polymorphism in exon 7 of the endothelial nitric ox... DisGeNET Detail
NOS3 Glu298Asp polymorphism interacts with virgin olive oil phenols to determine the postprandial en... DisGeNET Detail
We found that genotype Met/Met of the Val66Met polymorphism of the brain-derived neurotrophic factor... DisGeNET Detail
Endothelial nitric oxide synthase gene polymorphism (G894T) and diabetes mellitus (type II) among So... DisGeNET Detail
The I/D angiotensin-I converting enzyme gene polymorphism, gene polymorphisms of the endothelial nit... DisGeNET Detail
[Endothelial nitric oxide synthase tagging single nucleotide polymorphisms and recovery from aneurys... DisGeNET Detail

Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
dbSNP
rs1799983 dbSNP
Genome
hg38
Position
chr7:150,999,023-150,999,023
Variant Type
snv
Reference Allele
T
Alternative Allele
G
Filtering Status (HGVD)
PASS
# of samples (HGVD)
1204
Mean of sample read depth (HGVD)
82.41
Standard deviation of sample read depth (HGVD)
40.44
Number of reference allele (HGVD)
196
Number of alternative allele (HGVD)
2212
Allele Frequency (HGVD)
0.9186046511627907
Gene Symbol (HGVD)
NOS3
ToMMo VCF FILTER column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
PASS
Total VCF ID column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
rs1799983
Allele frequency, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
0.9145
Allele count in genotypes, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
15323
Total number of alleles in called genotypes (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
16756
East Asian Chromosome Counts (ExAC)
8614
East Asian Allele Counts (ExAC)
7723
East Asian Heterozygous Counts (ExAC)
795
East Asian Homozygous Counts (ExAC)
3464
East Asian Allele Frequency (ExAC)
0.8965637334571628
Chromosome Counts in All Race (ExAC)
119898
Allele Counts in All Race (ExAC)
90285
Heterozygous Counts in All Race (ExAC)
21151
Homozygous Counts in All Race (ExAC)
34567
Allele Frequency in All Race (ExAC)
0.7530150628033829
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