Annotation Detail

Information
Associated Genes
VEGFA
Associated Variants
POLR1C c.945+240786A>G
POLR1C c.945+240822A>G
NOS3 p.Asp298Glu (p.D298E) ( ENST00000297494.8, ENST00000461406.5, ENST00000467517.1, ENST00000484524.5 )
POLR1C c.945+240786A>G
POLR1C c.945+240822A>G
NOS3 p.Asp298Glu (p.D298E) ( ENST00000297494.8, ENST00000461406.5, ENST00000467517.1, ENST00000484524.5 )
Associated Disease
ABLEPHARON-MACROSTOMIA SYNDROME
Source Database
DisGeNET
Description
Heart rate (HR) was found to be significantly associated with the eNOS3 SNP (rs1799983) and arterial oxygen saturation of hemoglobin (SaO2) was found to be significantly associated with the VEGFA SNPs (rs13207351, rs1570360) in Han patients with AMS.
Pubmed
22729570
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00108576748832121
Year of publication
2012
Drugs