Frontotemporal Lobar Degeneration

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Information
Disease name
Frontotemporal Lobar Degeneration
Disease ID
Description
Disease area statistics
Chromosome band
Gene symbol Chromosome Start Stop The number of variant
GRN 17 44,345,302 44,353,106 4
MAPT 17 45,894,554 46,028,334 4
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04937452 Active, not recruiting Phase 2 Dopaminergic Therapy for Frontotemporal Dementia Patients June 3, 2021 April 1, 2024
NCT04516499 Active, not recruiting Neurofilament Surveillance Project (NSP) September 2, 2020 December 2026
NCT00604591 Completed Phase 2 Effects of Tolcapone on Frontotemporal Dementia July 2011 October 2014
NCT00613119 Completed PET Evaluation of Brain Peripheral Benzodiazepine Receptors Using [11C]PBR28 in Frontotemporal Dementia January 31, 2008 July 13, 2017
NCT00677885 Completed P-glycoprotein Function in Brain Diseases May 9, 2008 August 25, 2014
NCT01925196 Completed Natural History and Biomarkers of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Caused by the C9ORF72 Gene Mutation September 30, 2013
NCT00088751 Completed Treatment Study of Frontotemporal Dementia July 23, 2004 June 1, 2009
NCT02213458 Completed N/A Care Ecosystem: Navigating Patients and Families Through Stages of Care March 20, 2015 March 8, 2018
NCT02333942 Completed Dementia Signal Development Study of Nautilus NeuroWave TM for the Detection of Dementia May 2014 February 2015
NCT04977245 Completed N/A Mindfulness-Based Stress Reduction in Dementia Caregivers August 12, 2021 April 4, 2022
NCT02590276 Completed N/A Predict to Prevent Frontotemporal Lobar Degeneration (FDT) and Amyotrophic Lateral Sclerosis (ALS) October 8, 2015 October 27, 2020
NCT02889601 Completed DAPHNE Scale Validation in Frontotemporal Lobar Degeneration February 2013 December 31, 2015
NCT03508024 Completed Patients With Alzheimer's Disease or Related Youth Disease January 5, 2018 April 25, 2019
NCT04287738 Completed N/A Care Ecosystem: Navigating Patients and Families Through Stages of Care, Extension Trial March 20, 2015 May 20, 2022
NCT03606798 Completed N/A Multidisciplinary and Personalized Care of Behavioral Disorders in Frontotemporal Lobar Degeneration. June 21, 2018 October 6, 2021
NCT00187525 Completed Phase 4 A 52 Week Open Label Trial of Memantine for Frontotemporal Lobar Degeneration May 2004 October 2006
NCT05956834 Recruiting A Multi-Modal Remote Monitoring Platform for Frontotemporal Lobar Degeneration (FTLD) Syndromes July 28, 2023 December 30, 2026
NCT05456503 Recruiting Phase 3 PET Imaging Tau Accumulation in FTLD and Atypical Alzheimer's Using PI-2620 September 19, 2022 August 2026
NCT05741853 Recruiting N/A Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia May 1, 2023 November 30, 2027
NCT04635540 Unknown status N/A Decreased Empathy and Emotion Recognition in Patients With Neurodegenerative Disease July 22, 2019 July 2022
NCT02964611 Unknown status Social Cognition and Personality Changes in Alzheimer's & Parkinson's Disease & Frontotemporal Lobar Degeneration January 2013 December 2019
NCT02363062 Unknown status Identification of New FTLD Genes February 2, 2015 February 1, 2019
NCT01962064 Unknown status N/A Social Cognition in Ageing and in Frontotemporal Lobar Degeneration June 2013 November 2014
NCT04014673 Unknown status N/A Natural History Characterization in Symptomatic and Asymptomatic Progranuline Gene Mutation Carriers January 19, 2010 February 2022
NCT03030586 Unknown status ADDIA Proof-of-Performance Clinical Study September 1, 2016 June 30, 2021
MeSH unique ID (MeSH (Medical Subject Headings))
D057174