chr15:75041186:> Detail (hg19)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr15:75,041,186-75,048,948 |
| hg38 | chr15:74,748,845-74,756,607 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
| Score | Disease name | Description | Source | Pubmed | Links |
|---|---|---|---|---|---|
| 0.121 | squamous cell carcinoma | NA | BeFree,CTD_human | Detail | |
| 0.007 | Cardiovascular Diseases | NA | GAD | Detail | |
| <0.001 | cleft palate | NA | BeFree | Detail | |
| 0.002 | Colonic Polyps | NA | GAD | Detail | |
| 0.005 | colorectal carcinoma | Association between CYP1A2 and CYP1B1 polymorphisms and colorectal cancer risk: ... | BeFree | 25115775 | Detail |
| 0.133 | Colorectal Neoplasms | NA | CTD_human,GAD,LHGDN | Detail | |
| <0.001 | Coronary heart disease | NA | BeFree | Detail | |
| 0.002 | Mental Depression | NA | GAD | Detail | |
| 0.080 | depressive disorder | NA | RGD | Detail | |
| 0.120 | Diabetes Mellitus, Non-Insulin-Dependent | NA | CTD_human | Detail | |
| 0.002 | diarrhea | NA | GAD | Detail | |
| 0.002 | Dyskinesia, Drug-Induced | NA | GAD | Detail | |
| 0.005 | Endometrial Neoplasms | NA | GAD | Detail | |
| <0.001 | endometriosis | NA | BeFree | Detail | |
| 0.002 | epilepsy | NA | GAD | Detail | |
| 0.005 | Esophageal Neoplasms | NA | GAD | Detail | |
| 0.120 | Growth Disorders | NA | CTD_human | Detail | |
| 0.005 | Head and Neck Neoplasms | NA | GAD | Detail | |
| 0.120 | Hepatomegaly | NA | CTD_human | Detail | |
| 0.003 | Hypertensive disease | We investigated whether baseline coffee consumption is longitudinally associated... | BeFree,GAD | 25595320 | Detail |
| 0.080 | Icterus | NA | RGD | Detail | |
| 0.005 | Laryngeal neoplasm | NA | GAD | Detail | |
| 0.002 | chronic lymphocytic leukemia | NA | GAD | Detail | |
| 0.003 | Leukemia, Myelocytic, Acute | NA | LHGDN | Detail | |
| <0.001 | liver cirrhosis | For cytochrome P450 enzymes 1 (CYP1) family, the expression of CYP1A2 was decrea... | BeFree | 25024626 | Detail |
| <0.001 | Liver Cirrhosis, Alcoholic | For cytochrome P450 enzymes 1 (CYP1) family, the expression of CYP1A2 was decrea... | BeFree | 25024626 | Detail |
| 0.120 | Liver Cirrhosis, Experimental | NA | CTD_human | Detail | |
| 0.123 | Liver diseases | NA | BeFree,CTD_human,GAD | Detail | |
| 0.002 | Liver neoplasms | NA | BeFree | Detail | |
| 0.120 | Liver Neoplasms, Experimental | NA | CTD_human | Detail | |
| 0.132 | Chronic Obstructive Airway Disease | NA | BeFree,CTD_human,GAD,LHGDN | Detail | |
| 0.123 | Lung Neoplasms | NA | CTD_human,LHGDN | Detail | |
| 0.002 | Lymphoma, Follicular | NA | GAD | Detail | |
| 0.009 | Lymphoma, Non-Hodgkin | NA | GAD | Detail | |
| 0.003 | Malignant neoplasm of stomach | NA | BeFree,GAD | Detail | |
| 0.002 | Mesothelioma | NA | GAD | Detail | |
| 0.120 | methemoglobinemia | NA | CTD_human | Detail | |
| 0.005 | Mouth Neoplasms | NA | GAD | Detail | |
| 0.008 | myocardial infarction | NA | BeFree,GAD,LHGDN | Detail | |
| 0.002 | Nausea | NA | GAD | Detail | |
| 0.122 | Neural Tube Defects | NA | CTD_human,GAD | Detail | |
| <0.001 | ovarian carcinoma | NA | BeFree | Detail | |
| 0.005 | Pancreatic Neoplasm | NA | GAD,LHGDN | Detail | |
| 0.005 | Parkinson disease | NA | GAD | Detail | |
| 0.120 | Peripheral neuropathy | NA | CTD_human | Detail | |
| 0.005 | Pharyngeal Neoplasms | NA | GAD | Detail | |
| 0.002 | Pleural Neoplasms | NA | GAD | Detail | |
| <0.001 | polyps | NA | BeFree | Detail | |
| 0.005 | Disorders of Porphyrin Metabolism | NA | GAD | Detail | |
| 0.002 | Pruritus | NA | GAD | Detail | |
| <0.001 | Respiratory Distress Syndrome, Newborn | NA | BeFree | Detail | |
| 0.028 | schizophrenia | NA | BeFree,GAD | Detail | |
| 0.003 | paranoid schizophrenia | NA | LHGDN | Detail | |
| 0.120 | Splenic Diseases | NA | CTD_human | Detail | |
| 0.120 | Splenomegaly | NA | CTD_human | Detail | |
| 0.002 | Cerebrovascular accident | NA | GAD | Detail | |
| 0.003 | Testicular Neoplasms | NA | LHGDN | Detail | |
| 0.002 | thrombosis | NA | GAD | Detail | |
| 0.120 | Adverse reaction to drug | NA | CTD_human | Detail | |
| 0.002 | Vomiting | NA | GAD | Detail | |
| 0.002 | diffuse large B-cell lymphoma | NA | GAD | Detail | |
| <0.001 | Peripheral Vascular Diseases | NA | BeFree | Detail | |
| 0.003 | Polydipsia | NA | BeFree,GAD | Detail | |
| <0.001 | Polyglandular Type I Autoimmune Syndrome | NA | BeFree | Detail | |
| <0.001 | Squamous cell carcinoma of lung | NA | BeFree | Detail | |
| 0.005 | Migraine Disorders | NA | GAD | Detail | |
| <0.001 | Adenocarcinoma of lung (disorder) | NA | BeFree | Detail | |
| 0.006 | lingual-facial-buccal dyskinesia | Cytochrome P450 1A2 co-determines neuroleptic load and may diminish tardive dysk... | BeFree,GAD | 25602162 | Detail |
| <0.001 | Malignant neoplasm of mouth | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of heart | NA | BeFree | Detail | |
| 0.002 | Malignant neoplasm of testis | NA | GAD | Detail | |
| <0.001 | Liver Failure, Acute | NA | BeFree | Detail | |
| 0.128 | porphyria cutanea tarda | NA | BeFree,CTD_human,GAD,LHGDN | Detail | |
| <0.001 | Lichen Planus, Oral | We suggest CYP2D6 4 genotype as a disease-susceptible genotype and low or high C... | BeFree | 25240994 | Detail |
| 0.002 | cholangiocarcinoma | NA | GAD | Detail | |
| <0.001 | Lip and oral cavity carcinoma | NA | BeFree | Detail | |
| <0.001 | Congenital defects | NA | BeFree | Detail | |
| <0.001 | Chronic schizophrenia | NA | BeFree | Detail | |
| <0.001 | pancreatic carcinoma | NA | BeFree | Detail | |
| 0.002 | Substance-Related Disorders | NA | GAD | Detail | |
| <0.001 | Medullary carcinoma of thyroid | NA | BeFree | Detail | |
| <0.001 | Endometriosis of pelvis | NA | BeFree | Detail | |
| <0.001 | Hepatitis, Autoimmune | NA | BeFree | Detail | |
| 0.024 | Malignant neoplasm of lung | Four polymorphisms in the cytochrome P450 1A2 (CYP1A2) gene and lung cancer risk... | BeFree,GAD | 25081684 | Detail |
| 0.024 | Malignant neoplasm of lung | In summary, this meta-analysis suggests that CYP1A2*1F polymorphism is associate... | BeFree,GAD | 25472037 | Detail |
| 0.002 | age related macular degeneration | NA | GAD | Detail | |
| 0.080 | Sepsis | NA | BeFree,RGD | Detail | |
| 0.120 | Lung Injury | NA | CTD_human | Detail | |
| <0.001 | Transitional cell carcinoma of bladder | NA | BeFree | Detail | |
| <0.001 | Adenocarcinoma of pancreas | NA | BeFree | Detail | |
| 0.120 | Atrophic | NA | CTD_human | Detail | |
| <0.001 | Chronic liver disease | NA | BeFree | Detail | |
| 0.007 | Malignant neoplasm of liver | NA | GAD | Detail | |
| 0.005 | Malignant neoplasm of pancreas | NA | BeFree,GAD | Detail | |
| 0.024 | Malignant neoplasm of lung | These results suggest that the rs3569413 polymorphism of the CYP1A2 gene is asso... | BeFree | 23462460 | Detail |
| 0.005 | Carcinoma of lung | These results suggest that the rs3569413 polymorphism of the CYP1A2 gene is asso... | BeFree | 23462460 | Detail |
| 0.017 | Malignant neoplasm of prostate | NA | BeFree,GAD | Detail | |
| <0.001 | Abnormal involuntary movement | NA | BeFree | Detail | |
| <0.001 | Non-alcoholic Fatty Liver Disease | NA | BeFree | Detail | |
| 0.007 | endometrial carcinoma | NA | BeFree,GAD | Detail | |
| <0.001 | Respiratory distress | NA | BeFree | Detail | |
| <0.001 | Recurrent tumor | NA | BeFree | Detail | |
| 0.002 | Malignant neoplasm of esophagus | NA | GAD | Detail | |
| 0.002 | Carcinogenesis | NA | BeFree | Detail | |
| <0.001 | Chemical Carcinogenesis | NA | BeFree | Detail | |
| <0.001 | prostate carcinoma | NA | BeFree | Detail | |
| 0.003 | Hot flushes | NA | BeFree,GAD | Detail | |
| 0.005 | Carcinoma of lung | Four polymorphisms in the cytochrome P450 1A2 (CYP1A2) gene and lung cancer risk... | BeFree | 25081684 | Detail |
| 0.005 | Carcinoma of lung | In summary, this meta-analysis suggests that CYP1A2*1F polymorphism is associate... | BeFree | 25472037 | Detail |
| 0.006 | Tardive Dyskinesia | Cytochrome P450 1A2 co-determines neuroleptic load and may diminish tardive dysk... | BeFree,GAD | 25602162 | Detail |
| <0.001 | colon carcinoma | NA | BeFree | Detail | |
| <0.001 | stomach carcinoma | NA | BeFree | Detail | |
| 0.002 | Carcinoma of bladder | In summary, this meta-analysis suggests that CYP1A2*1F polymorphism is associate... | BeFree | 25472037 | Detail |
| <0.001 | Monosomy 22 | NA | BeFree | Detail | |
| <0.001 | Schizophrenia and related disorders | NA | BeFree | Detail | |
| <0.001 | Helicobacter pylori infection | NA | BeFree | Detail | |
| 0.002 | Carcinoma, Pancreatic Ductal | NA | GAD | Detail | |
| 0.003 | ovarian neoplasm | NA | LHGDN | Detail | |
| 0.002 | Genomic Instability | NA | GAD | Detail | |
| 0.002 | Acute coronary syndrome | NA | GAD | Detail | |
| <0.001 | Polyp of large intestine | NA | BeFree | Detail | |
| 0.006 | Malignant neoplasm of ovary | NA | BeFree,GAD | Detail | |
| 0.003 | Squamous cell carcinoma of the head and neck | NA | BeFree,GAD | Detail | |
| <0.001 | Uroporphyrinuria | NA | BeFree | Detail | |
| 0.002 | major depressive disorder | NA | GAD | Detail | |
| <0.001 | Sporadic porphyria cutanea tarda | NA | BeFree | Detail | |
| 0.001 | Adenoma of large intestine | NA | BeFree | Detail | |
| 0.002 | Testicular Germ Cell Tumor | NA | GAD | Detail | |
| 0.005 | Mammary Neoplasms | NA | LHGDN | Detail | |
| <0.001 | Hepatocarcinogenesis | NA | BeFree | Detail | |
| 0.046 | colorectal cancer | Association between CYP1A2 and CYP1B1 polymorphisms and colorectal cancer risk: ... | BeFree,GAD | 25115775 | Detail |
| <0.001 | Cirrhosis | For cytochrome P450 enzymes 1 (CYP1) family, the expression of CYP1A2 was decrea... | BeFree | 25024626 | Detail |
| <0.001 | Peripheral Arterial Diseases | NA | BeFree | Detail | |
| 0.003 | Mammographic Density | NA | BeFree,GAD | Detail | |
| 0.002 | Venous thromboembolism | NA | GAD | Detail | |
| <0.001 | uterine corpus cancer | NA | BeFree | Detail | |
| 0.002 | coronary artery disease | NA | GAD | Detail | |
| <0.001 | Cardiac Carcinoma | NA | BeFree | Detail | |
| <0.001 | Transformed migraine | NA | BeFree | Detail | |
| 0.120 | Precursor Cell Lymphoblastic Leukemia Lymphoma | NA | CTD_human | Detail | |
| 0.009 | liver carcinoma | For cytochrome P450 enzymes 1 (CYP1) family, the expression of CYP1A2 was decrea... | BeFree,GAD,LHGDN | 25024626 | Detail |
| 0.002 | caffeine stimulant related disorder | NA | GAD | Detail | |
| <0.001 | Congenital Abnormality | NA | BeFree | Detail | |
| <0.001 | adenocarcinoma | NA | BeFree | Detail | |
| 0.005 | adenoma | NA | BeFree,GAD | Detail | |
| 0.002 | congenital adrenal hyperplasia | NA | GAD | Detail | |
| 0.003 | amyotrophic lateral sclerosis | NA | BeFree,GAD | Detail | |
| <0.001 | arteriosclerosis | NA | BeFree | Detail | |
| 0.013 | rheumatoid arthritis | It was shown that CYP1A2*1F allele may be associated with LEF toxicity in patien... | BeFree,GAD,LHGDN | 25664505 | Detail |
| 0.005 | asthma | NA | BeFree,GAD | Detail | |
| <0.001 | atherosclerosis | NA | BeFree | Detail | |
| <0.001 | biliary atresia | NA | BeFree | Detail | |
| 0.016 | Malignant neoplasm of urinary bladder | In summary, this meta-analysis suggests that CYP1A2*1F polymorphism is associate... | BeFree,GAD | 25472037 | Detail |
| 0.006 | Bladder Neoplasm | NA | BeFree,LHGDN | Detail | |
| <0.001 | Malignant tumor of colon | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of endometrium | NA | BeFree | Detail | |
| <0.001 | Rectal Carcinoma | NA | BeFree | Detail |
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Association between CYP1A2 and CYP1B1 polymorphisms and colorectal cancer risk: a meta-analysis. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| We investigated whether baseline coffee consumption is longitudinally associated with risk of impair... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| For cytochrome P450 enzymes 1 (CYP1) family, the expression of CYP1A2 was decreased 90% in HCC, 80% ... | DisGeNET | Detail |
| For cytochrome P450 enzymes 1 (CYP1) family, the expression of CYP1A2 was decreased 90% in HCC, 80% ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Cytochrome P450 1A2 co-determines neuroleptic load and may diminish tardive dyskinesia by increased ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| We suggest CYP2D6 4 genotype as a disease-susceptible genotype and low or high CYP1A2 activity level... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Four polymorphisms in the cytochrome P450 1A2 (CYP1A2) gene and lung cancer risk: a meta-analysis. | DisGeNET | Detail |
| In summary, this meta-analysis suggests that CYP1A2*1F polymorphism is associated with lung cancer a... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| These results suggest that the rs3569413 polymorphism of the CYP1A2 gene is associated with an incre... | DisGeNET | Detail |
| These results suggest that the rs3569413 polymorphism of the CYP1A2 gene is associated with an incre... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Four polymorphisms in the cytochrome P450 1A2 (CYP1A2) gene and lung cancer risk: a meta-analysis. | DisGeNET | Detail |
| In summary, this meta-analysis suggests that CYP1A2*1F polymorphism is associated with lung cancer a... | DisGeNET | Detail |
| Cytochrome P450 1A2 co-determines neuroleptic load and may diminish tardive dyskinesia by increased ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In summary, this meta-analysis suggests that CYP1A2*1F polymorphism is associated with lung cancer a... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Association between CYP1A2 and CYP1B1 polymorphisms and colorectal cancer risk: a meta-analysis. | DisGeNET | Detail |
| For cytochrome P450 enzymes 1 (CYP1) family, the expression of CYP1A2 was decreased 90% in HCC, 80% ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| For cytochrome P450 enzymes 1 (CYP1) family, the expression of CYP1A2 was decreased 90% in HCC, 80% ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| It was shown that CYP1A2*1F allele may be associated with LEF toxicity in patients with RA. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In summary, this meta-analysis suggests that CYP1A2*1F polymorphism is associated with lung cancer a... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- dbSNP
- rs3569413 dbSNP
- Genome
- hg19
- Position
- chr15:75,041,186-75,048,948
- Variant Type
- snv
Genome browser