chr11:637269:> Detail (hg19)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr11:637,269-640,706 |
| hg38 | chr11:637,269-640,706 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
| Score | Disease name | Description | Source | Pubmed | Links |
|---|---|---|---|---|---|
| 0.120 | Child Development Disorders, Pervasive | NA | CTD_human | Detail | |
| 0.003 | delusional disorder | NA | BeFree,GAD | Detail | |
| <0.001 | dependent personality disorder | NA | BeFree | Detail | |
| 0.015 | Mental Depression | NA | BeFree,GAD | Detail | |
| 0.003 | depressive disorder | NA | BeFree | Detail | |
| <0.001 | Down syndrome | NA | BeFree | Detail | |
| 0.003 | Drug abuse | NA | BeFree,GAD | Detail | |
| 0.003 | Dyskinetic syndrome | NA | LHGDN | Detail | |
| <0.001 | Eating Disorders | NA | BeFree | Detail | |
| <0.001 | eclampsia | NA | BeFree | Detail | |
| 0.002 | Endocrine System Diseases | NA | GAD | Detail | |
| 0.002 | Headache | NA | GAD | Detail | |
| <0.001 | Atrial Septal Defects | NA | BeFree | Detail | |
| 0.012 | heroin dependence | NA | BeFree,GAD,LHGDN | Detail | |
| <0.001 | Hyperphagia | NA | BeFree | Detail | |
| 0.003 | Disruptive, Impulse Control, and Conduct Disorders | NA | BeFree,GAD | Detail | |
| 0.002 | Chronic Obstructive Airway Disease | NA | GAD | Detail | |
| 0.001 | Marijuana Abuse | NA | BeFree | Detail | |
| <0.001 | medulloblastoma | NA | BeFree | Detail | |
| 0.003 | nicotine dependence | NA | BeFree,GAD | Detail | |
| <0.001 | Nicotine withdrawal | Brain systems associated with reward salience may become primed and overreactive... | BeFree | 24659022 | Detail |
| 0.090 | obesity | Association of VNTR polymorphisms in DRD4, 5-HTT and DAT1 genes with obesity. | BeFree,GAD,RGD | 25687785 | Detail |
| 0.007 | obsessive-compulsive disorder | NA | BeFree,GAD | Detail | |
| 0.001 | oppositional defiant disorder | NA | BeFree | Detail | |
| 0.002 | osteochondritis dissecans | NA | BeFree | Detail | |
| 0.003 | Pain | NA | BeFree,GAD | Detail | |
| <0.001 | panic disorder | NA | BeFree | Detail | |
| 0.007 | Parkinson disease | NA | GAD | Detail | |
| 0.003 | Gambling, Pathological | NA | BeFree,GAD | Detail | |
| 0.010 | Personality Disorders | NA | BeFree,GAD | Detail | |
| <0.001 | Pituitary Diseases | NA | BeFree | Detail | |
| 0.002 | pre-eclampsia | NA | GAD | Detail | |
| 0.002 | Pregnancy Complications | NA | GAD | Detail | |
| 0.002 | Prenatal Exposure Delayed Effects | NA | GAD | Detail | |
| 0.002 | Psychoses, Substance-Induced | NA | GAD | Detail | |
| 0.014 | Psychotic Disorders | NA | BeFree,GAD | Detail | |
| 0.329 | attention deficit hyperactivity disorder | Meta-analyses of pooled ORs support association of schizophrenia to the Ser311Cy... | BeFree | 15802092 | Detail |
| 0.002 | retinoblastoma | NA | GAD | Detail | |
| <0.001 | schizoaffective disorder | NA | BeFree | Detail | |
| 0.226 | schizophrenia | NA | BeFree,CTD_human,GAD,LHGDN | Detail | |
| <0.001 | Residual schizophrenia | NA | BeFree | Detail | |
| <0.001 | Sialorrhea | Genetic association between the DRD4 promoter polymorphism and clozapine-induced... | BeFree | 25304228 | Detail |
| <0.001 | Specific reading disorder | NA | BeFree | Detail | |
| <0.001 | substance dependence | NA | BeFree | Detail | |
| <0.001 | Substance Use Disorders | The dopamine D4 receptor gene (DRD4) has been implicated in psychiatric disorder... | BeFree | 25107677 | Detail |
| 0.125 | tic disorder | NA | BeFree,CTD_human,GAD | Detail | |
| 0.002 | Tobacco use disorder | NA | GAD | Detail | |
| 0.004 | Gilles de la Tourette syndrome | Variable number tandem repeats in dopamine receptor D4 in Tourette's syndrome. | BeFree,GAD | 25258183 | Detail |
| <0.001 | Unipolar Depression | TPH, SLC6A2, SLC6A3, DRD2 and DRD4 Polymorphisms and Neuroendocrine Factors Pred... | BeFree | 25642918 | Detail |
| 0.009 | Weight Gain | NA | GAD | Detail | |
| <0.001 | Central Nervous System Neoplasms | NA | BeFree | Detail | |
| 0.001 | seasonal affective disorder | NA | BeFree | Detail | |
| <0.001 | Agitation | NA | BeFree | Detail | |
| 0.017 | Alcohol abuse | NA | BeFree,GAD | Detail | |
| <0.001 | Depressive Symptoms | NA | BeFree | Detail | |
| <0.001 | Withdrawal Symptoms | NA | BeFree | Detail | |
| <0.001 | conduct disorder | NA | BeFree | Detail | |
| <0.001 | somatization | NA | BeFree | Detail | |
| 0.010 | Migraine Disorders | NA | BeFree,GAD,LHGDN | Detail | |
| 0.011 | lingual-facial-buccal dyskinesia | NA | BeFree,GAD | Detail | |
| 0.003 | Hyperkinetic conduct disorder of childhood | NA | BeFree,GAD | Detail | |
| 0.002 | Malnutrition | NA | GAD | Detail | |
| <0.001 | Chronic psychosis | NA | BeFree | Detail | |
| <0.001 | Dysphoric mood | NA | BeFree | Detail | |
| 0.001 | Antisocial behavior | The differential susceptibility theory was examined by investigating the presenc... | BeFree | 24929324 | Detail |
| 0.026 | Personality Traits | NA | GAD | Detail | |
| 0.120 | Amphetamine-Related Disorders | NA | CTD_human | Detail | |
| 0.120 | Attention Deficit and Disruptive Behavior Disorders | NA | CTD_human | Detail | |
| 0.002 | Substance-Related Disorders | NA | GAD | Detail | |
| 0.001 | Alcohol or Other Drugs use | NA | BeFree | Detail | |
| <0.001 | Selenium deficiency | NA | BeFree | Detail | |
| 0.005 | Malignant neoplasm of lung | NA | BeFree,GAD | Detail | |
| 0.001 | Drug usage | NA | BeFree | Detail | |
| 0.005 | Bedwetting | NA | GAD,LHGDN | Detail | |
| <0.001 | Expressed Emotion | The differential susceptibility theory was examined by investigating the presenc... | BeFree | 24929324 | Detail |
| 0.002 | Atrophic | NA | GAD | Detail | |
| 0.003 | Common Migraine | NA | BeFree,LHGDN | Detail | |
| 0.003 | Hyperkinetic conduct disorder | NA | BeFree,GAD | Detail | |
| 0.001 | Nonorganic psychosis | NA | BeFree | Detail | |
| <0.001 | Diagnosis, Psychiatric | NA | BeFree | Detail | |
| 0.002 | Inattention | NA | BeFree | Detail | |
| <0.001 | Anxiety and fear | NA | BeFree | Detail | |
| <0.001 | dyslexia | NA | BeFree | Detail | |
| <0.001 | Overweight | NA | BeFree | Detail | |
| 0.007 | body mass | NA | GAD | Detail | |
| 0.001 | Delinquent behavior | NA | BeFree | Detail | |
| <0.001 | Opiate Addiction | NA | BeFree | Detail | |
| 0.013 | Mood Disorders | NA | BeFree,GAD,LHGDN | Detail | |
| <0.001 | Alcohol problem | NA | BeFree | Detail | |
| 0.010 | Heroin Abuse | NA | BeFree,GAD | Detail | |
| <0.001 | Emotional problems | NA | BeFree | Detail | |
| <0.001 | Carcinoma of lung | NA | BeFree | Detail | |
| 0.008 | Tardive Dyskinesia | NA | BeFree,GAD | Detail | |
| 0.001 | heavy drinking | Regardless of DRD4 genotype, friends' alcohol use at age 17 predicted greater al... | BeFree | 25457740 | Detail |
| <0.001 | Moderate obesity | NA | BeFree | Detail | |
| <0.001 | Substance abuse problem | NA | BeFree | Detail | |
| <0.001 | Chronic Daily Headache | NA | BeFree | Detail | |
| 0.002 | Sleep Disorders | NA | GAD | Detail | |
| <0.001 | Childhood aggression | NA | BeFree | Detail | |
| <0.001 | Female sexual dysfunction | NA | BeFree | Detail | |
| 0.329 | attention deficit hyperactivity disorder | Genetics of preparation and response control in ADHD: the role of DRD4 and DAT1. | BeFree,CTD_human,GAD,LHGDN,RGD | 24521003 | Detail |
| 0.329 | attention deficit hyperactivity disorder | The aim of this study was to investigate the relationships between repeat polymo... | BeFree,CTD_human,GAD,LHGDN,RGD | 24825354 | Detail |
| 0.329 | attention deficit hyperactivity disorder | Results indicated that adolescents with the DRD4 7r allele who experienced less ... | BeFree,CTD_human,GAD,LHGDN,RGD | 25194232 | Detail |
| 0.329 | attention deficit hyperactivity disorder | Humans with seven or more repeats in exon III of the DRD4 gene (long DRD4 carrie... | BeFree,CTD_human,GAD,LHGDN,RGD | 25244120 | Detail |
| 0.329 | attention deficit hyperactivity disorder | DRD4 VNTRs, observed stranger fear in preschoolers and later ADHD symptoms. | BeFree,CTD_human,GAD,LHGDN,RGD | 25262643 | Detail |
| 0.329 | attention deficit hyperactivity disorder | The DRD4 4-repeat allele was associated with increased inattentive ADHD symptoms... | BeFree,CTD_human,GAD,LHGDN,RGD | 25271118 | Detail |
| 0.329 | attention deficit hyperactivity disorder | We also genotyped the exon 3 VNTR of DRD4, the 7-repeat allele of which is also ... | BeFree,CTD_human,GAD,LHGDN,RGD | 25656223 | Detail |
| 0.329 | attention deficit hyperactivity disorder | The 5-repeat allele of a common length polymorphism in the gene that encodes the... | BeFree,CTD_human,GAD,LHGDN,RGD | 25659462 | Detail |
| 0.329 | attention deficit hyperactivity disorder | Moreover, possessing greater genetic risk on three dopaminergic genes (DAT1, DRD... | BeFree,CTD_human,GAD,LHGDN,RGD | 25704081 | Detail |
| 0.329 | attention deficit hyperactivity disorder | The methylation of one critical CpG site located upstream of DRD4 was shown to a... | BeFree,CTD_human,GAD,LHGDN,RGD | 25840828 | Detail |
| 0.005 | major depressive disorder | TPH, SLC6A2, SLC6A3, DRD2 and DRD4 Polymorphisms and Neuroendocrine Factors Pred... | BeFree,GAD | 25642918 | Detail |
| 0.002 | Systemic arterial pressure | NA | GAD | Detail | |
| 0.005 | Methamphetamine abuse | NA | BeFree,GAD | Detail | |
| <0.001 | Autism Spectrum Disorders | NA | BeFree | Detail | |
| 0.002 | colorectal cancer | NA | GAD | Detail | |
| 0.120 | Separation anxiety disorder of childhood | NA | CTD_human | Detail | |
| 0.001 | MAJOR AFFECTIVE DISORDER 2 | NA | BeFree | Detail | |
| 0.004 | NEUROTICISM | NA | BeFree,GAD | Detail | |
| 0.001 | MAJOR AFFECTIVE DISORDER 1 | NA | BeFree | Detail | |
| 0.120 | NOVELTY SEEKING PERSONALITY TRAIT | NA | CTD_human | Detail | |
| <0.001 | PANIC DISORDER 1 | NA | BeFree | Detail | |
| 0.001 | MAJOR AFFECTIVE DISORDER 4 | NA | BeFree | Detail | |
| 0.001 | MAJOR AFFECTIVE DISORDER 5 | NA | BeFree | Detail | |
| 0.001 | MAJOR AFFECTIVE DISORDER 6 | NA | BeFree | Detail | |
| 0.001 | bulimia nervosa | NA | BeFree | Detail | |
| 0.001 | Major affective disorder 7 | NA | BeFree | Detail | |
| 0.001 | MAJOR AFFECTIVE DISORDER 8 | NA | BeFree | Detail | |
| 0.001 | MAJOR AFFECTIVE DISORDER 9 | NA | BeFree | Detail | |
| 0.009 | Weight Gain Adverse Event | NA | GAD | Detail | |
| 0.120 | Parkinson disease, late-onset | NA | CTD_human | Detail | |
| 0.002 | Finding relating to sexuality and sexual activity | NA | GAD | Detail | |
| 0.002 | Affective Disorders, Psychotic | NA | GAD | Detail | |
| 0.022 | Alcoholic Intoxication, Chronic | The present study aimed to evaluate the association of alcohol dependence and al... | BeFree,GAD | 25035107 | Detail |
| 0.022 | Alcoholic Intoxication, Chronic | Meta-analysis of six genes (BDNF, DRD1, DRD3, DRD4, GRIN2B and MAOA) involved in... | BeFree,GAD | 25660313 | Detail |
| 0.003 | Alzheimer's disease | NA | BeFree,GAD | Detail | |
| 0.004 | anorexia nervosa | NA | BeFree,LHGDN | Detail | |
| 0.002 | Anxiety Disorders | Interaction effects of the COMT and DRD4 genes with anxiety-related traits on se... | BeFree | 25011686 | Detail |
| 0.007 | As If Personality | NA | GAD | Detail | |
| 0.003 | autistic disorder | NA | BeFree,GAD | Detail | |
| 0.004 | Mental disorders | The dopamine D4 receptor gene (DRD4) has been implicated in psychiatric disorder... | BeFree,GAD | 25107677 | Detail |
| 0.025 | bipolar disorder | NA | BeFree,GAD,LHGDN | Detail | |
| 0.002 | Malignant neoplasm of urinary bladder | NA | GAD | Detail | |
| <0.001 | borderline personality disorder | NA | BeFree | Detail | |
| <0.001 | bronchopulmonary dysplasia | NA | BeFree | Detail | |
| <0.001 | Bulimia | NA | BeFree | Detail | |
| <0.001 | Non-small cell lung carcinoma | NA | BeFree | Detail |
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Brain systems associated with reward salience may become primed and overreactive at nicotine replace... | DisGeNET | Detail |
| Association of VNTR polymorphisms in DRD4, 5-HTT and DAT1 genes with obesity. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Meta-analyses of pooled ORs support association of schizophrenia to the Ser311Cys polymorphism in DR... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Genetic association between the DRD4 promoter polymorphism and clozapine-induced sialorrhea. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The dopamine D4 receptor gene (DRD4) has been implicated in psychiatric disorders in which deficits ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Variable number tandem repeats in dopamine receptor D4 in Tourette's syndrome. | DisGeNET | Detail |
| TPH, SLC6A2, SLC6A3, DRD2 and DRD4 Polymorphisms and Neuroendocrine Factors Predict SSRIs Treatment ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The differential susceptibility theory was examined by investigating the presence of interaction eff... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The differential susceptibility theory was examined by investigating the presence of interaction eff... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Regardless of DRD4 genotype, friends' alcohol use at age 17 predicted greater alcohol use and more f... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Genetics of preparation and response control in ADHD: the role of DRD4 and DAT1. | DisGeNET | Detail |
| The aim of this study was to investigate the relationships between repeat polymorphisms in dopamine ... | DisGeNET | Detail |
| Results indicated that adolescents with the DRD4 7r allele who experienced less responsive and stimu... | DisGeNET | Detail |
| Humans with seven or more repeats in exon III of the DRD4 gene (long DRD4 carriers) sometimes demons... | DisGeNET | Detail |
| DRD4 VNTRs, observed stranger fear in preschoolers and later ADHD symptoms. | DisGeNET | Detail |
| The DRD4 4-repeat allele was associated with increased inattentive ADHD symptoms (p = .03). | DisGeNET | Detail |
| We also genotyped the exon 3 VNTR of DRD4, the 7-repeat allele of which is also an established risk ... | DisGeNET | Detail |
| The 5-repeat allele of a common length polymorphism in the gene that encodes the dopamine D4 recepto... | DisGeNET | Detail |
| Moreover, possessing greater genetic risk on three dopaminergic genes (DAT1, DRD2, and DRD4) relativ... | DisGeNET | Detail |
| The methylation of one critical CpG site located upstream of DRD4 was shown to affect its transcript... | DisGeNET | Detail |
| TPH, SLC6A2, SLC6A3, DRD2 and DRD4 Polymorphisms and Neuroendocrine Factors Predict SSRIs Treatment ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The present study aimed to evaluate the association of alcohol dependence and alcohol dependence-rel... | DisGeNET | Detail |
| Meta-analysis of six genes (BDNF, DRD1, DRD3, DRD4, GRIN2B and MAOA) involved in neuroplasticity and... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Interaction effects of the COMT and DRD4 genes with anxiety-related traits on selective attention. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The dopamine D4 receptor gene (DRD4) has been implicated in psychiatric disorders in which deficits ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- dbSNP
- rs386602276 dbSNP
- Genome
- hg19
- Position
- chr11:637,269-640,706
- Variant Type
- snv
Genome browser