Sialorrhea
Information
- Disease name
- Sialorrhea
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05164367 | Active, not recruiting | Early Phase 1 | Pharmacokinetics of Atropine Oral Gel | October 1, 2022 | July 2024 |
| NCT00491894 | Completed | Phase 3 | Safety and Efficacy Study of Oral Glycopyrrolate Liquid for the Treatment of Pathologic (Chronic Moderate to Severe) Drooling in Pediatric Patients 3 to 18 Years of Age With Cerebral Palsy or Other Neurologic Conditions | March 2007 | June 2008 |
| NCT00683891 | Completed | FazaClo Outcomes in the Control of Schizophrenia (FOCUS) Study Survey | |||
| NCT01118143 | Completed | N/A | Oral Health Literacy Tailored Communication | June 2010 | February 2012 |
| NCT01191398 | Completed | N/A | Effectiveness of Atropine and Glycopyrrolate to Reduce Hyper Salivation With Ketamine Sedation | June 2010 | January 2011 |
| NCT01551940 | Completed | Phase 2 | Toxin Treatment for Amyotrophic Lateral Sclerosis (ALS) Related Sialorrhea | February 2012 | March 2014 |
| NCT01653132 | Completed | Phase 2 | Incobotulinum Toxin A (Xeomin®) for Troublesome Sialorrhea in Parkinson's Disease (PD)/Parkinsonism | March 2012 | September 2014 |
| NCT01994109 | Completed | Phase 3 | Efficacy and Safety Study of MYOBLOC® Followed by Open-Label Multiple-Treatment With MYOBLOC® in the Treatment of Troublesome Sialorrhea in Adult Subjects | November 2013 | January 2017 |
| NCT06101160 | Completed | Botulinum Toxin Injection for Sialorrhea in Cerebral Palsy | June 30, 2021 | April 30, 2023 | |
| NCT02425176 | Completed | Phase 2/Phase 3 | Botulinum Toxin-A for Sialorrhoea Treatment in Asian Adults With Neurological Diseases | September 2009 | April 2014 |
| NCT02610868 | Completed | Phase 3 | Open-Label and Single-Arm Study of MYOBLOC® in the Treatment of Troublesome Sialorrhea in Adults | October 2015 | June 2017 |
| NCT02613494 | Completed | Phase 1/Phase 2 | Clozapine-induced Hypersalivation - Feasibility Trial | January 25, 2016 | February 23, 2018 |
| NCT04197037 | Completed | Prevalence of Sialorrhea in Patients Treated With Clozapine | March 20, 2018 | December 31, 2021 | |
| NCT00125203 | Completed | Phase 2/Phase 3 | Study of Myobloc in the Treatment of Sialorrhea (Drooling) in Patients With Amyotrophic Lateral Sclerosis (ALS) | July 2003 | August 2007 |
| NCT05097079 | Not yet recruiting | Phase 3 | Efficacy and Safety Study of MYOBLOC® in the Treatment of Sialorrhea in Pediatric Subjects | November 30, 2023 | March 30, 2024 |
| NCT04873115 | Recruiting | Phase 4 | Double-blind, Placebo-controlled, Randomized Clinical Trial Comparing the Efficacy and Safety of Sialanar Plus orAl rehabiLitation Against Placebo Plus Oral Rehabilitation for chIldren and Adolescents With seVere Sialorrhoea and Neurodisabilties, | May 10, 2021 | June 10, 2023 |
| NCT03747536 | Unknown status | Phase 2 | Ipratropium Bromide Spray as Treatment for Sialorrhea in Children | January 1, 2019 | January 1, 2021 |
| NCT02382198 | Unknown status | Phase 2 | Study of Glycopyrrolate for Moderate-to-severe Sialorrhea in Parkinson's Disease | July 2016 | December 2018 |
| NCT01489904 | Unknown status | Phase 2/Phase 3 | Application of Botulinum Toxin Type A in Salivary Glands in the Treatment of Drooling in Patients With Cerebral Palsy | November 2011 | November 2012 |
| NCT03704168 | Withdrawn | N/A | Safety and Efficacy of Cryoablation in Management of Sialorrhea in Patients With Neurological Disorders | May 1, 2019 | April 30, 2021 |
- MeSH unique ID (MeSH (Medical Subject Headings))
- D012798