Annotation Detail

Information
Associated Genes
DRD4
Associated Variants
DRD4 MUTATION
DRD4 MUTATION
Associated Disease
Mental disorders
Source Database
DisGeNET
Description
The dopamine D4 receptor gene (DRD4) has been implicated in psychiatric disorders in which deficits of self-regulation are a prominent feature (e.g., attention-deficit hyperactivity disorder and substance use disorders) and in dopamine D4 receptor insensitivity within prefrontal regions of the brain.
Pubmed
25107677
Section of the abstract supporting the evidence
BACKGROUND
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.00426712508316415
Drugs