chr5:132481609:> Detail (hg38)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr5:131,817,301-131,826,469 |
| hg38 | chr5:132,481,609-132,490,777 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
| Score | Disease name | Description | Source | Pubmed | Links |
|---|---|---|---|---|---|
| <0.001 | renal cell carcinoma | NA | BeFree | Detail | |
| 0.001 | squamous cell carcinoma | NA | BeFree | Detail | |
| <0.001 | Cardiomyopathy, Dilated | NA | BeFree | Detail | |
| 0.008 | celiac disease | NA | BeFree,GAD,LHGDN | Detail | |
| 0.001 | Malignant tumor of cervix | BANF1 is downregulated by IRF1-regulated microRNA-203 in cervical cancer. | BeFree | 25658920 | Detail |
| <0.001 | colitis | IRF1 was upregulated in human IBD and in the colon epithelium of mice with dextr... | BeFree | 25208103 | Detail |
| <0.001 | ulcerative colitis | Additionally, IRF1 was correlated with high-sensitivity C-reactive protein, eryt... | BeFree | 25208103 | Detail |
| <0.001 | colorectal carcinoma | A positive feedback loop between IRF1 and miR-29b may contribute to the sensitiv... | BeFree | 25592039 | Detail |
| 0.080 | allergic conjunctivitis | NA | RGD | Detail | |
| 0.003 | Crohn Disease | Additionally, IRF1 was correlated with high-sensitivity C-reactive protein, eryt... | BeFree,GAD | 25208103 | Detail |
| <0.001 | Down syndrome | NA | BeFree | Detail | |
| 0.080 | Endometrial Neoplasms | NA | RGD | Detail | |
| <0.001 | Gingival Diseases | NA | BeFree | Detail | |
| 0.002 | Graft-vs-Host Disease | NA | GAD | Detail | |
| 0.003 | Graves Disease | NA | BeFree,GAD | Detail | |
| <0.001 | Heart failure | NA | BeFree | Detail | |
| <0.001 | congestive heart failure | NA | BeFree | Detail | |
| 0.003 | hepatitis B | NA | BeFree,GAD | Detail | |
| 0.008 | hepatitis C | NA | BeFree,GAD,LHGDN | Detail | |
| 0.002 | HIV Infections | NA | BeFree | Detail | |
| 0.002 | Hypersensitivity | NA | GAD | Detail | |
| 0.002 | Immediate hypersensitivity | NA | GAD | Detail | |
| 0.003 | Inflammation | NA | LHGDN | Detail | |
| <0.001 | Inflammatory Bowel Diseases | Opposite effects of interferon regulatory factor 1 and osteopontin on the apopto... | BeFree | 25208103 | Detail |
| <0.001 | ischemia | IRF-1 promotes liver transplant ischemia/reperfusion injury via hepatocyte IL-15... | BeFree | 25964490 | Detail |
| 0.002 | leukemia | NA | BeFree | Detail | |
| <0.001 | Acute lymphocytic leukemia | NA | BeFree | Detail | |
| 0.002 | Leukemia, Myelocytic, Acute | NA | BeFree | Detail | |
| <0.001 | myeloid leukemia | NA | BeFree | Detail | |
| <0.001 | Myeloid Leukemia, Chronic | NA | BeFree | Detail | |
| <0.001 | Leukemia, Myeloid, Chronic-Phase | NA | BeFree | Detail | |
| <0.001 | acute promyelocytic leukemia | NA | BeFree | Detail | |
| <0.001 | lipoma | NA | BeFree | Detail | |
| <0.001 | Liver neoplasms | NA | BeFree | Detail | |
| 0.080 | Lung diseases | NA | RGD | Detail | |
| 0.002 | Chronic Obstructive Airway Disease | NA | GAD | Detail | |
| 0.120 | Lung Neoplasms | NA | CTD_human | Detail | |
| <0.001 | Lupus Erythematosus, Systemic | CAF1 and IRF1 expression in SLE and NHC peripheral mononuclear cells were compar... | BeFree | 24836587 | Detail |
| <0.001 | Lupus Erythematosus, Systemic | Interferon regulatory factor 1 marks activated genes and can induce target gene ... | BeFree | 25418955 | Detail |
| 0.003 | malaria | NA | BeFree,LHGDN | Detail | |
| 0.005 | Malaria, Falciparum | NA | BeFree,GAD | Detail | |
| 0.001 | Malignant neoplasm of stomach | NA | BeFree | Detail | |
| <0.001 | medulloblastoma | NA | BeFree | Detail | |
| 0.001 | melanoma | NA | BeFree | Detail | |
| <0.001 | mitral valve stenosis | NA | BeFree | Detail | |
| <0.001 | multiple myeloma | NA | BeFree | Detail | |
| 0.006 | multiple sclerosis | NA | BeFree,GAD,LHGDN | Detail | |
| 0.001 | Myelodysplasia | NA | BeFree | Detail | |
| <0.001 | myocarditis | NA | BeFree | Detail | |
| <0.001 | Neoplasm Metastasis | NA | BeFree | Detail | |
| <0.001 | neuroblastoma | NA | BeFree | Detail | |
| <0.001 | Degenerative polyarthritis | NA | BeFree | Detail | |
| 0.001 | ovarian carcinoma | NA | BeFree | Detail | |
| <0.001 | Periodontal Diseases | NA | BeFree | Detail | |
| <0.001 | Adenomatous Polyposis Coli | NA | BeFree | Detail | |
| 0.001 | Preleukemia | NA | BeFree | Detail | |
| <0.001 | psoriasis | NA | BeFree | Detail | |
| 0.080 | Reperfusion Injury | NA | RGD | Detail | |
| 0.085 | Respiratory Syncytial Virus Infections | NA | BeFree,GAD,RGD | Detail | |
| <0.001 | Skin Neoplasms | These studies define a novel mechanism associated with skin tumor promotion by t... | BeFree | 24464587 | Detail |
| <0.001 | smallpox | NA | BeFree | Detail | |
| 0.120 | Cerebrovascular accident | NA | CTD_human | Detail | |
| <0.001 | subacute sclerosing panencephalitis | NA | BeFree | Detail | |
| 0.002 | thrombosis | NA | GAD | Detail | |
| 0.009 | tuberculosis | NA | BeFree,GAD,LHGDN | Detail | |
| 0.080 | ureteral obstruction | NA | RGD | Detail | |
| 0.002 | Viremia | NA | GAD | Detail | |
| 0.001 | Virus Diseases | By virtue of its interaction with specific DNA sequence, IRF-1 regulates the tra... | BeFree | 25312803 | Detail |
| <0.001 | diffuse large B-cell lymphoma | NA | BeFree | Detail | |
| 0.003 | Bronchial Hyperreactivity | NA | BeFree,GAD | Detail | |
| <0.001 | Synovial Cyst | NA | BeFree | Detail | |
| <0.001 | acute leukemia | NA | BeFree | Detail | |
| 0.120 | Myocardial Ischemia | NA | CTD_human | Detail | |
| <0.001 | allergic asthma | NA | BeFree | Detail | |
| <0.001 | Sotos' syndrome | NA | BeFree | Detail | |
| 0.003 | Carcinoma, Endometrioid | NA | LHGDN | Detail | |
| <0.001 | pancreatic carcinoma | The expression levels of IRF1 and IRF2 were decreased and increased, respectivel... | BeFree | 24632547 | Detail |
| <0.001 | Muscular Dystrophy, Facioscapulohumeral | NA | BeFree | Detail | |
| <0.001 | Testicular embryonal carcinoma | NA | BeFree | Detail | |
| 0.002 | Malignant neoplasm of lung | NA | GAD | Detail | |
| <0.001 | Childhood asthma | NA | BeFree | Detail | |
| <0.001 | Miller Dieker syndrome | NA | BeFree | Detail | |
| <0.001 | gastric adenocarcinoma | NA | BeFree | Detail | |
| <0.001 | Liver and Intrahepatic Biliary Tract Carcinoma | NA | BeFree | Detail | |
| <0.001 | Adenocarcinoma Of Esophagus | NA | BeFree | Detail | |
| <0.001 | Solid tumour | NA | BeFree | Detail | |
| 0.004 | cervix carcinoma | BANF1 is downregulated by IRF1-regulated microRNA-203 in cervical cancer. | BeFree,GAD | 25658920 | Detail |
| <0.001 | Leber congenital amaurosis | NA | BeFree | Detail | |
| <0.001 | Ventricular hypertrophy | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of liver | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of pancreas | The expression levels of IRF1 and IRF2 were decreased and increased, respectivel... | BeFree | 24632547 | Detail |
| <0.001 | juvenile myelomonocytic leukemia | NA | BeFree | Detail | |
| <0.001 | Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site | NA | BeFree | Detail | |
| <0.001 | Hematopoietic Neoplasms | NA | BeFree | Detail | |
| <0.001 | Metabolic syndrome X | NA | BeFree | Detail | |
| 0.003 | Hepatitis B, Chronic | NA | BeFree,GAD | Detail | |
| 0.009 | Hepatitis C, Chronic | NA | BeFree,GAD,LHGDN | Detail | |
| 0.002 | Carcinogenesis | In this study, we sought to determine whether IRF1 downregulation underlies onco... | BeFree | 25497010 | Detail |
| <0.001 | Leukemogenesis | NA | BeFree | Detail | |
| <0.001 | Epithelial ovarian cancer | NA | BeFree | Detail | |
| 0.002 | breast carcinoma | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of gastrointestinal tract | NA | BeFree | Detail | |
| <0.001 | colon carcinoma | NA | BeFree | Detail | |
| 0.121 | stomach carcinoma | NA | BeFree,UNIPROT | Detail | |
| <0.001 | Central neuroblastoma | NA | BeFree | Detail | |
| 0.120 | 5q-syndrome | NA | BeFree,CTD_human | Detail | |
| <0.001 | Invasive breast carcinoma | NA | BeFree | Detail | |
| <0.001 | Endothelial dysfunction | NA | BeFree | Detail | |
| <0.001 | Metastatic Prostate Carcinoma | NA | BeFree | Detail | |
| <0.001 | Acute coronary syndrome | NA | BeFree | Detail | |
| <0.001 | West Nile viral infection | NA | BeFree | Detail | |
| <0.001 | Invasive Ductal Breast Carcinoma | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of ovary | NA | BeFree | Detail | |
| <0.001 | Primary HIV infection | NA | BeFree | Detail | |
| <0.001 | Myxoid cyst | NA | BeFree | Detail | |
| <0.001 | Myelodysplastic Syndrome with Isolated del(5q) | NA | BeFree | Detail | |
| <0.001 | Acute Myeloid Leukemia Arising from Previous Myelodysplastic Syndrome | NA | BeFree | Detail | |
| <0.001 | Atypical Ductal Breast Hyperplasia | NA | BeFree | Detail | |
| <0.001 | Sporadic Breast Carcinoma | NA | BeFree | Detail | |
| <0.001 | Vascular lesions | NA | BeFree | Detail | |
| <0.001 | Cardiomyopathy, Familial Idiopathic | NA | BeFree | Detail | |
| 0.011 | Mammary Neoplasms | NA | BeFree,LHGDN | Detail | |
| <0.001 | colorectal cancer | A positive feedback loop between IRF1 and miR-29b may contribute to the sensitiv... | BeFree | 25592039 | Detail |
| 0.005 | Fibrinogen Adverse Event | NA | GAD | Detail | |
| <0.001 | Chromosome 5, trisomy 5q | NA | BeFree | Detail | |
| <0.001 | Precursor Cell Lymphoblastic Leukemia Lymphoma | NA | BeFree | Detail | |
| 0.002 | liver carcinoma | NA | BeFree | Detail | |
| 0.003 | myelodysplastic syndrome | NA | BeFree,LHGDN | Detail | |
| <0.001 | Lipomatosis, Multiple | NA | BeFree | Detail | |
| 0.005 | Juvenile arthritis | NA | BeFree,GAD | Detail | |
| <0.001 | Allergic disposition | NA | BeFree | Detail | |
| 0.014 | Infection | NA | LHGDN | Detail | |
| <0.001 | juvenile rheumatoid arthritis | NA | BeFree | Detail | |
| <0.001 | Experimental Organism Basal Cell Carcinoma | NA | BeFree | Detail | |
| 0.005 | Fibrinogen Adverse Event | [Novel loci, including those related to Crohn disease, psoriasis, and inflammati... | GAD | 20031577 | Detail |
| <0.001 | arteriosclerosis | NA | BeFree | Detail | |
| 0.002 | arthritis | NA | GAD | Detail | |
| <0.001 | rheumatoid arthritis | Non-HLA single nucleotide polymorphisms (SNPs) in the intergenic regions LOC3892... | BeFree | 25014791 | Detail |
| 0.011 | asthma | The IRF1 locus is a strong candidate region for male-specific asthma susceptibil... | BeFree,GAD | 24824216 | Detail |
| <0.001 | ataxia telangiectasia | NA | BeFree | Detail | |
| <0.001 | atherosclerosis | NA | BeFree | Detail | |
| 0.005 | Behcet Syndrome | NA | BeFree,GAD,LHGDN | Detail | |
| 0.002 | Malignant neoplasm of urinary bladder | NA | GAD | Detail | |
| 0.003 | Bladder Neoplasm | NA | LHGDN | Detail | |
| 0.002 | Malignant neoplasm of breast | NA | BeFree | Detail | |
| 0.005 | Bronchiolitis, Viral | NA | GAD | Detail | |
| <0.001 | Malignant tumor of colon | NA | BeFree | Detail | |
| <0.001 | Noninfiltrating Intraductal Carcinoma | NA | BeFree | Detail |
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| BANF1 is downregulated by IRF1-regulated microRNA-203 in cervical cancer. | DisGeNET | Detail |
| IRF1 was upregulated in human IBD and in the colon epithelium of mice with dextran sulfate sodium-in... | DisGeNET | Detail |
| Additionally, IRF1 was correlated with high-sensitivity C-reactive protein, erythrocyte sedimentatio... | DisGeNET | Detail |
| A positive feedback loop between IRF1 and miR-29b may contribute to the sensitivity of CRC cells to ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Additionally, IRF1 was correlated with high-sensitivity C-reactive protein, erythrocyte sedimentatio... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Opposite effects of interferon regulatory factor 1 and osteopontin on the apoptosis of epithelial ce... | DisGeNET | Detail |
| IRF-1 promotes liver transplant ischemia/reperfusion injury via hepatocyte IL-15/IL-15Rα production. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| CAF1 and IRF1 expression in SLE and NHC peripheral mononuclear cells were compared by quantitative r... | DisGeNET | Detail |
| Interferon regulatory factor 1 marks activated genes and can induce target gene expression in system... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| These studies define a novel mechanism associated with skin tumor promotion by the anthrone class of... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| By virtue of its interaction with specific DNA sequence, IRF-1 regulates the transcription of a set ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The expression levels of IRF1 and IRF2 were decreased and increased, respectively, in the pancreatic... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| BANF1 is downregulated by IRF1-regulated microRNA-203 in cervical cancer. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The expression levels of IRF1 and IRF2 were decreased and increased, respectively, in the pancreatic... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In this study, we sought to determine whether IRF1 downregulation underlies oncogenesis induced by R... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| A positive feedback loop between IRF1 and miR-29b may contribute to the sensitivity of CRC cells to ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| [Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Non-HLA single nucleotide polymorphisms (SNPs) in the intergenic regions LOC389203|RBPJ, LOC10013113... | DisGeNET | Detail |
| The IRF1 locus is a strong candidate region for male-specific asthma susceptibility due to the assoc... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- dbSNP
- rs10479002 dbSNP
- Genome
- hg38
- Position
- chr5:132,481,609-132,490,777
- Variant Type
- snv
Genome browser