Annotation Detail

Information
Associated Genes
IRF1
Associated Variants
IRF1 MUTATION
IRF1 MUTATION
Associated Disease
Virus Diseases
Source Database
DisGeNET
Description
By virtue of its interaction with specific DNA sequence, IRF-1 regulates the transcription of a set of target genes which play essential roles in various physiological and pathological processes, including viral infection, tumor immune surveillance, pro-inflammatory injury, development of immunity system.
Pubmed
25312803
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
2
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00135720936040152
Drugs