Annotation Detail
Information
- Associated Genes
- IRF1
- Associated Variants
-
IRF1 MUTATION
IRF1 MUTATION - Associated Disease
- asthma
- Source Database
- DisGeNET
- Description
- The IRF1 locus is a strong candidate region for male-specific asthma susceptibility due to the association and validation we demonstrate here, the known role of IRF1 in asthma-relevant immune pathways and prior reports of sex-specific differences in interferon responses.
- Pubmed
- 24824216
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 10
- Original source reporting the Gene Disease association
- BeFree,GAD
- DisGENET score for the Gene Disease association
- 0.0105538954027293
Drugs