chr2:233760270:> Detail (hg38)

Information

Genome

Assembly Position
hg19 chr2:234,668,916-234,681,946 
hg38 chr2:233,760,270-233,773,300

HGVS

Type Transcript Protein
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

[No Data.]

Prediction

[No Data.]

ClinVar

Clinical Significance
Review star [No Data.]
Show details
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score Disease name Description Source Pubmed Links
<0.001 squamous cell carcinoma NA BeFree Detail
0.004 Cardiovascular Diseases NA BeFree,GAD Detail
0.002 brain ischemia NA GAD Detail
0.002 Uterine Cervical Neoplasm NA GAD Detail
0.036 cholelithiasis Both patients developed gallstones; however the father, who had undergone surger... BeFree,GAD,LHGDN 25153905 Detail
0.036 cholelithiasis UGT1A1 and UGT1A6 variants might be potentially associated with gallstone-relate... BeFree,GAD,LHGDN 26039129 Detail
0.003 ulcerative colitis NA BeFree,GAD Detail
0.008 Colonic Neoplasms NA BeFree,GAD,LHGDN Detail
0.008 colorectal carcinoma UGT1A levels in tumor tissues may be a suitable predictive biomarker to stratify... BeFree 25210794 Detail
0.008 colorectal carcinoma Influence of UGT1A1 gene methylation level in colorectal cancer cells on the sen... BeFree 25260839 Detail
0.008 colorectal carcinoma We prospectively studied the relation between the UGT1A1 genotype and the safety... BeFree 25880011 Detail
0.022 Colorectal Neoplasms NA GAD,LHGDN Detail
0.002 Connective Tissue Diseases NA GAD Detail
0.001 Coronary Arteriosclerosis NA BeFree Detail
0.001 Coronary heart disease NA BeFree Detail
0.262 Crigler Najjar syndrome, type 1 A novel stop codon mutation in exon 1 (558C>A) of the UGT1A1 gene in a Thai neon... BeFree,CTD_human,LHGDN,UNIPROT 25729974 Detail
<0.001 Crohn Disease NA BeFree Detail
0.003 cystic fibrosis NA BeFree,LHGDN Detail
0.002 Deafness NA GAD Detail
<0.001 Dehydration NA BeFree Detail
<0.001 Hepatitis D Infection NA BeFree Detail
0.120 contact dermatitis NA CTD_human Detail
<0.001 Diabetes NA BeFree Detail
<0.001 diabetes mellitus NA BeFree Detail
0.080 Diabetes Mellitus, Insulin-Dependent NA RGD Detail
0.005 Diabetes Mellitus, Non-Insulin-Dependent NA BeFree,GAD Detail
0.016 diarrhea The UGT1A1 genotype was confirmed to be associated with increased risks of irino... BeFree,GAD 25880011 Detail
0.002 DNA Damage NA GAD Detail
0.005 drug allergy NA GAD Detail
0.002 Duodenal Neoplasms NA GAD Detail
0.010 Endometrial Neoplasms NA GAD,LHGDN Detail
0.002 epilepsy NA GAD Detail
0.003 Esophageal Neoplasms NA BeFree,GAD Detail
<0.001 Fatigue NA BeFree Detail
0.003 Fatty Liver We analyzed total bilirubin levels, which are linked to fatty liver in severe ob... BeFree,GAD 25246029 Detail
0.002 Fetal Diseases NA GAD Detail
0.005 Gall Bladder Diseases NA BeFree,GAD,LHGDN Detail
0.295 Gilbert Disease (disorder) Correlation of UGT1A1 TATA-box polymorphism and jaundice in breastfed newborns-e... BeFree,CTD_human,GAD,UNIPROT 23981182 Detail
0.295 Gilbert Disease (disorder) The high levels of bilirubin could be related to the co-inheritance of Gilbert s... BeFree,CTD_human,GAD,UNIPROT 24620945 Detail
0.295 Gilbert Disease (disorder) Although Gilbert's syndrome is usually quite benign UGT1A1(TA)n genotyping is im... BeFree,CTD_human,GAD,UNIPROT 24785582 Detail
0.295 Gilbert Disease (disorder) The relationship was strongest for heavy smokers (⩾20 cigarettes per day) at age... BeFree,CTD_human,GAD,UNIPROT 25086287 Detail
0.295 Gilbert Disease (disorder) Outcome and toxicities associated to chemotherapy in children with acute lymphob... BeFree,CTD_human,GAD,UNIPROT 25855413 Detail
0.295 Gilbert Disease (disorder) The combination of new missense mutation with [A(TA)7TAA] dinucleotide repeat in... BeFree,CTD_human,GAD,UNIPROT 25887876 Detail
0.004 breast carcinoma We did not observe an association between potential functional genetic polymorph... BeFree 23935996 Detail
0.028 Malignant neoplasm of breast We did not observe an association between potential functional genetic polymorph... BeFree 23935996 Detail
0.002 Hearing Loss, Partial NA GAD Detail
0.002 cardiac arrest NA BeFree Detail
0.003 Hemoglobinopathies NA BeFree,GAD Detail
0.002 Hemolysis (disorder) NA GAD Detail
0.007 HIV Infections NA BeFree,GAD Detail
0.123 Hodgkin Disease NA BeFree,CTD_human,GAD Detail
0.223 Hyperbilirubinemia We have investigated the UGT1A1 polymorphism frequency and its relation to sever... BeFree,CTD_human,GAD,LHGDN 23981182 Detail
0.223 Hyperbilirubinemia FOLFIRI combined with bevacizumab as first-line treatment for metastatic colorec... BeFree,CTD_human,GAD,LHGDN 24642571 Detail
0.223 Hyperbilirubinemia Although Gilbert's syndrome is usually quite benign UGT1A1(TA)n genotyping is im... BeFree,CTD_human,GAD,LHGDN 24785582 Detail
0.223 Hyperbilirubinemia Influence of UGT1A1 6, 27, and 28 polymorphisms on nilotinib-induced hyperbiliru... BeFree,CTD_human,GAD,LHGDN 24898899 Detail
0.223 Hyperbilirubinemia Association of UGT1A1 variants and hyperbilirubinemia in breast-fed full-term Ch... BeFree,CTD_human,GAD,LHGDN 25102181 Detail
0.223 Hyperbilirubinemia We previously reported that maximal body weight loss (inadequate feeding) is an ... BeFree,CTD_human,GAD,LHGDN 25391605 Detail
0.223 Hyperbilirubinemia Using an exome-wide approach we identified coding variants on UGT1A1 and UGT1A6 ... BeFree,CTD_human,GAD,LHGDN 26039129 Detail
0.002 Hyperbilirubinemia, Hereditary NA GAD Detail
0.003 Hypercholesterolemia NA BeFree,GAD Detail
0.080 hyperthyroidism NA RGD Detail
0.005 Inflammation NA GAD Detail
<0.001 Inflammatory Bowel Diseases NA BeFree Detail
<0.001 influenza NA BeFree Detail
0.003 intermittent claudication NA BeFree,GAD Detail
0.002 Intestinal Polyps NA GAD Detail
0.005 Icterus NA GAD Detail
0.014 neonatal jaundice NA BeFree,GAD Detail
0.124 kernicterus Crigler-Najjar syndrome is the severe inherited form of unconjugated hyperbiliru... BeFree,CTD_human,LHGDN 25315738 Detail
0.002 Kidney Neoplasm NA GAD Detail
0.002 leukemia NA GAD Detail
<0.001 Acute lymphocytic leukemia UGT1A1*28 polymorphism and acute lymphoblastic leukemia in children: a Danish ca... BeFree 25105254 Detail
<0.001 Acute lymphocytic leukemia Outcome and toxicities associated to chemotherapy in children with acute lymphob... BeFree 25855413 Detail
<0.001 Myeloid Leukemia, Chronic Influence of UGT1A1 6, 27, and 28 polymorphisms on nilotinib-induced hyperbiliru... BeFree 24898899 Detail
0.013 leukopenia The most common grade 4 adverse event in patients with the UGT1A1*6 genotypes wa... BeFree 25055799 Detail
0.013 leukopenia The UGT1A1 genotype was confirmed to be associated with increased risks of irino... BeFree 25880011 Detail
0.008 Liver diseases NA BeFree,GAD Detail
<0.001 Liver neoplasms NA BeFree Detail
0.002 Lung Neoplasms NA GAD Detail
0.001 Malignant neoplasm of stomach Differential expression of the UGT1A family of genes in stomach cancer tissues. BeFree 25712374 Detail
0.002 Musculoskeletal Diseases NA GAD Detail
0.003 myocardial infarction NA BeFree,GAD Detail
0.005 Neoplasm Metastasis NA BeFree,GAD,LHGDN Detail
0.147 neutropenia The most common grade 4 adverse event in patients with the UGT1A1*6 genotypes wa... BeFree,CTD_human,GAD 25055799 Detail
0.147 neutropenia The UGT1A1 genotype was confirmed to be associated with increased risks of irino... BeFree,CTD_human,GAD 25880011 Detail
0.003 obesity Body fat percentage is a major determinant of total bilirubin independently of U... BeFree,GAD 24901842 Detail
0.003 obesity Our study demonstrates that reduced hepatic Ugt1a activity during obesity likely... BeFree,GAD 26334566 Detail
<0.001 Obesity, Morbid We analyzed total bilirubin levels, which are linked to fatty liver in severe ob... BeFree 25246029 Detail
0.002 Osteoporosis, Postmenopausal NA GAD Detail
<0.001 ovarian carcinoma NA BeFree Detail
0.002 Adenomatous Polyposis Coli NA GAD Detail
<0.001 Precancerous Conditions NA BeFree Detail
0.002 Pregnancy Complications, Hematologic NA GAD Detail
<0.001 Seizures NA BeFree Detail
<0.001 Septicemia NA BeFree Detail
<0.001 siderosis Both patients developed gallstones; however the father, who had undergone surger... BeFree 25153905 Detail
0.002 Dermatologic disorders NA GAD Detail
0.004 hereditary spherocytosis NA BeFree,LHGDN Detail
0.080 Starvation NA RGD Detail
0.002 Stomach Neoplasms NA GAD Detail
0.003 Cerebrovascular accident NA BeFree,GAD Detail
0.008 thalassemia NA BeFree,GAD,LHGDN Detail
<0.001 tuberculosis NA BeFree Detail
0.120 Adverse reaction to drug NA CTD_human Detail
0.002 Genitourinary Neoplasms NA GAD Detail
0.028 Malignant neoplasm of breast However, when this relation was assessed within strata based on estrogen-related... BeFree 22199302 Detail
0.003 Mammographic Density However, when this relation was assessed within strata based on estrogen-related... BeFree 22199302 Detail
0.004 breast carcinoma However, when this relation was assessed within strata based on estrogen-related... BeFree 22199302 Detail
<0.001 Small cell carcinoma of lung Irinotecan showed efficacy in patients with recurrent and refractory SCLC; UGT1A... BeFree 25450281 Detail
0.007 Premature Birth NA GAD Detail
<0.001 Myocardial Ischemia NA BeFree Detail
<0.001 esophageal carcinoma NA BeFree Detail
<0.001 Malignant tumor of small intestine NA BeFree Detail
<0.001 Liver Failure, Acute NA BeFree Detail
0.004 Aortic Aneurysm, Thoracic NA BeFree Detail
<0.001 cholangiocarcinoma NA BeFree Detail
<0.001 Rotor syndrome NA BeFree Detail
<0.001 pancreatic carcinoma NA BeFree Detail
<0.001 small intestine carcinoma NA BeFree Detail
0.005 Biliary calculi NA LHGDN Detail
0.012 Malignant neoplasm of lung NA BeFree,GAD Detail
0.002 multiple chemical sensitivity NA GAD Detail
<0.001 Sepsis NA BeFree Detail
0.120 Carcinoma, Small Cell NA CTD_human Detail
<0.001 Chronic heart failure NA BeFree Detail
0.010 Unconjugated hyperbilirubinemia Gilbert's syndrome is one of the most common metabolic syndromes in the human po... BeFree 24785582 Detail
0.010 Unconjugated hyperbilirubinemia The enzyme uridine diphosphate glucuronosyltransferase polypeptide 1A1 (UGT1A1) ... BeFree 25086287 Detail
0.010 Unconjugated hyperbilirubinemia Crigler-Najjar syndrome is the severe inherited form of unconjugated hyperbiliru... BeFree 25315738 Detail
0.010 Unconjugated hyperbilirubinemia Our result suggests an important role for homozygous c.558C>A mutations in the U... BeFree 25729974 Detail
0.360 Lucey-Driscoll syndrome (disorder) NA CTD_human,ORPHANET,UNIPROT Detail
<0.001 Cancer of Head and Neck NA BeFree Detail
<0.001 Liver and Intrahepatic Biliary Tract Carcinoma NA BeFree Detail
<0.001 Squamous cell carcinoma of esophagus NA BeFree Detail
<0.001 Solid tumour NA BeFree Detail
<0.001 Malignant neoplasm of liver NA BeFree Detail
<0.001 Malignant neoplasm of pancreas NA BeFree Detail
0.004 Malignant neoplasm of prostate The UGT1 locus is a determinant of prostate cancer recurrence after prostatectom... BeFree,GAD 25452636 Detail
<0.001 nephrolithiasis This is the first known study to identify the association between SNPs in the UG... BeFree 25151207 Detail
<0.001 Dysequilibrium syndrome NA BeFree Detail
<0.001 Non-alcoholic Fatty Liver Disease NA BeFree Detail
0.008 endometrial carcinoma NA BeFree,GAD Detail
<0.001 Metabolic syndrome X Gilbert's syndrome is one of the most common metabolic syndromes in the human po... BeFree 24785582 Detail
<0.001 Hepatitis C, Chronic NA BeFree Detail
<0.001 Malignant neoplasm of esophagus NA BeFree Detail
<0.001 Neonatal unconjugated hyperbilirubinemia NA BeFree Detail
<0.001 Factor V Leiden mutation NA BeFree Detail
<0.001 Carcinoma of larynx NA BeFree Detail
0.001 Carcinogenesis NA BeFree Detail
0.001 prostate carcinoma The UGT1 locus is a determinant of prostate cancer recurrence after prostatectom... BeFree 25452636 Detail
0.004 breast carcinoma Therefore, we aimed to investigate possible associations between germline geneti... BeFree 25648141 Detail
0.001 colon carcinoma NA BeFree Detail
0.001 stomach carcinoma Differential expression of the UGT1A family of genes in stomach cancer tissues. BeFree 25712374 Detail
<0.001 Malignant Female Reproductive System Neoplasm NA BeFree Detail
0.003 choledocholithiasis NA BeFree,GAD Detail
<0.001 Premenopausal breast cancer NA BeFree Detail
<0.001 Febrile Neutropenia NA BeFree Detail
<0.001 Arteriopathic disease NA BeFree Detail
<0.001 Colorectal cancer recurrent Previous reports of the influence of UGT1A1 gene polymorphisms on the pharmacoki... BeFree 24382596 Detail
<0.001 Pancreatic carcinoma non-resectable In particular, we focus on Abstract #4124, which investigated the potential pred... BeFree 25076337 Detail
<0.001 Diffuse large B-cell lymphoma refractory UGT1A1 *6 polymorphism predicts outcome in elderly patients with relapsed or ref... BeFree 25055799 Detail
0.049 Hyperbilirubinemia, Neonatal Our findings added to the understanding of the significance of UGT1A1 in associa... BeFree,GAD,LHGDN 25102181 Detail
0.049 Hyperbilirubinemia, Neonatal Association of neonatal hyperbilirubinemia in breast-fed infants with UGT1A1 or ... BeFree,GAD,LHGDN 25391605 Detail
0.049 Hyperbilirubinemia, Neonatal Role of extrahepatic UDP-glucuronosyltransferase 1A1: Advances in understanding ... BeFree,GAD,LHGDN 26342858 Detail
0.002 Drug-Induced Liver Injury NA GAD Detail
0.005 ovarian neoplasm NA GAD,LHGDN Detail
0.008 cholecystolithiasis Both patients developed gallstones; however the father, who had undergone surger... BeFree,GAD 25153905 Detail
0.008 cholecystolithiasis UGT1A1 and UGT1A6 variants might be potentially associated with gallstone-relate... BeFree,GAD 26039129 Detail
0.008 Colorectal cancer metastatic To report a metastatic colorectal cancer patient with hyperbilirubinemia treated... BeFree 24642571 Detail
0.008 Colorectal cancer metastatic A phase I study of UGT1A1 *28/*6 genotype-directed dosing of irinotecan (CPT-11)... BeFree 25427841 Detail
0.006 Malignant neoplasm of ovary NA BeFree,GAD Detail
0.002 Gastrointestinal toxicity NA GAD Detail
0.002 Mammographic breast density NA GAD Detail
0.002 Adenoma of large intestine NA GAD Detail
<0.001 Classical Hodgkin's Lymphoma The number of association studies on cHL prognosis is limited with one consisten... BeFree 25205514 Detail
<0.001 differentiated thyroid gland carcinoma UGT1A haplotypes associate with T4 dosage in DTC patients, but the effect accoun... BeFree 24910925 Detail
0.002 hearing impairment NA GAD Detail
0.002 Severe diarrhea NA BeFree Detail
<0.001 alpha^+^ Thalassemia NA BeFree Detail
0.006 Mammary Neoplasms NA BeFree,LHGDN Detail
<0.001 Hepatocarcinogenesis NA BeFree Detail
0.053 colorectal cancer UGT1A levels in tumor tissues may be a suitable predictive biomarker to stratify... BeFree,GAD 25210794 Detail
0.053 colorectal cancer Influence of UGT1A1 gene methylation level in colorectal cancer cells on the sen... BeFree,GAD 25260839 Detail
0.053 colorectal cancer We prospectively studied the relation between the UGT1A1 genotype and the safety... BeFree,GAD 25880011 Detail
0.003 Mammographic Density NA BeFree,GAD Detail
<0.001 uterine corpus cancer NA BeFree Detail
0.008 coronary artery disease NA BeFree,GAD Detail
0.003 Precursor Cell Lymphoblastic Leukemia Lymphoma UGT1A1*28 polymorphism and acute lymphoblastic leukemia in children: a Danish ca... BeFree,LHGDN 25105254 Detail
0.003 Precursor Cell Lymphoblastic Leukemia Lymphoma Outcome and toxicities associated to chemotherapy in children with acute lymphob... BeFree,LHGDN 25855413 Detail
0.004 liver carcinoma NA BeFree,GAD Detail
0.120 Acute kidney injury NA CTD_human Detail
0.001 SPHEROCYTOSIS, TYPE 1 (disorder) NA BeFree Detail
0.009 Deficiency of glucose-6-phosphate dehydrogenase NA BeFree,GAD Detail
<0.001 Breastfeeding Jaundice NA BeFree Detail
0.002 Infection NA GAD Detail
<0.001 Lymphoblastic leukemia in children UGT1A1*28 polymorphism and acute lymphoblastic leukemia in children: a Danish ca... BeFree 25105254 Detail
0.002 Hearing Loss NA GAD Detail
<0.001 Abdominal Pain NA BeFree Detail
0.003 acromegaly NA BeFree,GAD Detail
<0.001 adenocarcinoma NA BeFree Detail
<0.001 adenoma NA BeFree Detail
0.002 agranulocytosis NA GAD Detail
0.003 alpha-Thalassemia NA BeFree,GAD Detail
<0.001 anemia NA BeFree Detail
<0.001 Cooley's anemia NA BeFree Detail
0.001 Anemia, Hemolytic NA BeFree Detail
0.029 Anemia, Sickle Cell NA BeFree,GAD,LHGDN Detail
<0.001 asthma A study of 41 patients, 78% (32/41) of whom were non-Hispanic whites, with mild ... BeFree 25192553 Detail
0.002 atherosclerosis NA GAD Detail
0.003 beta thalassemia NA BeFree,GAD Detail
<0.001 borderline personality disorder NA BeFree Detail
0.028 Malignant neoplasm of breast Therefore, we aimed to investigate possible associations between germline geneti... BeFree,GAD 25648141 Detail
<0.001 bronchopulmonary dysplasia NA BeFree Detail
0.001 Malignant tumor of colon NA BeFree Detail
<0.001 Malignant neoplasm of endometrium NA BeFree Detail
<0.001 Malignant neoplasm of larynx NA BeFree Detail
<0.001 Rectal Carcinoma NA BeFree Detail
0.003 Non-small cell lung carcinoma NA BeFree,GAD Detail
0.002 renal cell carcinoma NA GAD Detail
Annotation

Annotations

DescrptionSourceLinks
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Both patients developed gallstones; however the father, who had undergone surgery for the removal of... DisGeNET Detail
UGT1A1 and UGT1A6 variants might be potentially associated with gallstone-related cholecystectomy ri... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
UGT1A levels in tumor tissues may be a suitable predictive biomarker to stratify CRC patients for ga... DisGeNET Detail
Influence of UGT1A1 gene methylation level in colorectal cancer cells on the sensitivity of the chem... DisGeNET Detail
We prospectively studied the relation between the UGT1A1 genotype and the safety of irinotecan-based... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
A novel stop codon mutation in exon 1 (558C>A) of the UGT1A1 gene in a Thai neonate with Crigler-Naj... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The UGT1A1 genotype was confirmed to be associated with increased risks of irinotecan-induced grade ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
We analyzed total bilirubin levels, which are linked to fatty liver in severe obesity, and observed ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Correlation of UGT1A1 TATA-box polymorphism and jaundice in breastfed newborns-early presentation of... DisGeNET Detail
The high levels of bilirubin could be related to the co-inheritance of Gilbert syndrome determined e... DisGeNET Detail
Although Gilbert's syndrome is usually quite benign UGT1A1(TA)n genotyping is important in exclusion... DisGeNET Detail
The relationship was strongest for heavy smokers (⩾20 cigarettes per day) at age 53 with mean FEV1 4... DisGeNET Detail
Outcome and toxicities associated to chemotherapy in children with acute lymphoblastic leukemia and ... DisGeNET Detail
The combination of new missense mutation with [A(TA)7TAA] dinucleotide repeat in UGT1A1 gene promote... DisGeNET Detail
We did not observe an association between potential functional genetic polymorphisms in the estrogen... DisGeNET Detail
We did not observe an association between potential functional genetic polymorphisms in the estrogen... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
We have investigated the UGT1A1 polymorphism frequency and its relation to severity of hyperbilirubi... DisGeNET Detail
FOLFIRI combined with bevacizumab as first-line treatment for metastatic colorectal cancer patients ... DisGeNET Detail
Although Gilbert's syndrome is usually quite benign UGT1A1(TA)n genotyping is important in exclusion... DisGeNET Detail
Influence of UGT1A1 6, 27, and 28 polymorphisms on nilotinib-induced hyperbilirubinemia in Japanese ... DisGeNET Detail
Association of UGT1A1 variants and hyperbilirubinemia in breast-fed full-term Chinese infants. DisGeNET Detail
We previously reported that maximal body weight loss (inadequate feeding) is an independent risk fac... DisGeNET Detail
Using an exome-wide approach we identified coding variants on UGT1A1 and UGT1A6 genes in association... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Crigler-Najjar syndrome is the severe inherited form of unconjugated hyperbilirubinaemia due to muta... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
UGT1A1*28 polymorphism and acute lymphoblastic leukemia in children: a Danish case-control study. DisGeNET Detail
Outcome and toxicities associated to chemotherapy in children with acute lymphoblastic leukemia and ... DisGeNET Detail
Influence of UGT1A1 6, 27, and 28 polymorphisms on nilotinib-induced hyperbilirubinemia in Japanese ... DisGeNET Detail
The most common grade 4 adverse event in patients with the UGT1A1*6 genotypes was neutropenia (88.9%... DisGeNET Detail
The UGT1A1 genotype was confirmed to be associated with increased risks of irinotecan-induced grade ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Differential expression of the UGT1A family of genes in stomach cancer tissues. DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The most common grade 4 adverse event in patients with the UGT1A1*6 genotypes was neutropenia (88.9%... DisGeNET Detail
The UGT1A1 genotype was confirmed to be associated with increased risks of irinotecan-induced grade ... DisGeNET Detail
Body fat percentage is a major determinant of total bilirubin independently of UGT1A1*28 polymorphis... DisGeNET Detail
Our study demonstrates that reduced hepatic Ugt1a activity during obesity likely contributes to redu... DisGeNET Detail
We analyzed total bilirubin levels, which are linked to fatty liver in severe obesity, and observed ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Both patients developed gallstones; however the father, who had undergone surgery for the removal of... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
However, when this relation was assessed within strata based on estrogen-related factors, a few SNPs... DisGeNET Detail
However, when this relation was assessed within strata based on estrogen-related factors, a few SNPs... DisGeNET Detail
However, when this relation was assessed within strata based on estrogen-related factors, a few SNPs... DisGeNET Detail
Irinotecan showed efficacy in patients with recurrent and refractory SCLC; UGT1A1 FNx01 28 polymorph... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Gilbert's syndrome is one of the most common metabolic syndromes in the human population characteris... DisGeNET Detail
The enzyme uridine diphosphate glucuronosyltransferase polypeptide 1A1 (UGT1A1) is solely responsibl... DisGeNET Detail
Crigler-Najjar syndrome is the severe inherited form of unconjugated hyperbilirubinaemia due to muta... DisGeNET Detail
Our result suggests an important role for homozygous c.558C>A mutations in the UGT1A1 gene in the de... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The UGT1 locus is a determinant of prostate cancer recurrence after prostatectomy. DisGeNET Detail
This is the first known study to identify the association between SNPs in the UGT1A-3'-UTR and ataza... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Gilbert's syndrome is one of the most common metabolic syndromes in the human population characteris... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The UGT1 locus is a determinant of prostate cancer recurrence after prostatectomy. DisGeNET Detail
Therefore, we aimed to investigate possible associations between germline genetic polymorphisms with... DisGeNET Detail
NA DisGeNET Detail
Differential expression of the UGT1A family of genes in stomach cancer tissues. DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Previous reports of the influence of UGT1A1 gene polymorphisms on the pharmacokinetics of irinotecan... DisGeNET Detail
In particular, we focus on Abstract #4124, which investigated the potential predictive role of human... DisGeNET Detail
UGT1A1 *6 polymorphism predicts outcome in elderly patients with relapsed or refractory diffuse larg... DisGeNET Detail
Our findings added to the understanding of the significance of UGT1A1 in association with neonatal h... DisGeNET Detail
Association of neonatal hyperbilirubinemia in breast-fed infants with UGT1A1 or SLCOs polymorphisms. DisGeNET Detail
Role of extrahepatic UDP-glucuronosyltransferase 1A1: Advances in understanding breast milk-induced ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Both patients developed gallstones; however the father, who had undergone surgery for the removal of... DisGeNET Detail
UGT1A1 and UGT1A6 variants might be potentially associated with gallstone-related cholecystectomy ri... DisGeNET Detail
To report a metastatic colorectal cancer patient with hyperbilirubinemia treated with a combination ... DisGeNET Detail
A phase I study of UGT1A1 *28/*6 genotype-directed dosing of irinotecan (CPT-11) in Korean patients ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The number of association studies on cHL prognosis is limited with one consistent association for th... DisGeNET Detail
UGT1A haplotypes associate with T4 dosage in DTC patients, but the effect accounts for only 2% of th... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
UGT1A levels in tumor tissues may be a suitable predictive biomarker to stratify CRC patients for ga... DisGeNET Detail
Influence of UGT1A1 gene methylation level in colorectal cancer cells on the sensitivity of the chem... DisGeNET Detail
We prospectively studied the relation between the UGT1A1 genotype and the safety of irinotecan-based... DisGeNET Detail
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UGT1A1*28 polymorphism and acute lymphoblastic leukemia in children: a Danish case-control study. DisGeNET Detail
Outcome and toxicities associated to chemotherapy in children with acute lymphoblastic leukemia and ... DisGeNET Detail
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UGT1A1*28 polymorphism and acute lymphoblastic leukemia in children: a Danish case-control study. DisGeNET Detail
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A study of 41 patients, 78% (32/41) of whom were non-Hispanic whites, with mild to moderate asthma i... DisGeNET Detail
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Therefore, we aimed to investigate possible associations between germline genetic polymorphisms with... DisGeNET Detail
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Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
dbSNP
rs8175347 dbSNP
Genome
hg38
Position
chr2:233,760,270-233,773,300
Variant Type
snv
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