Annotation Detail

Information
Associated Genes
UGT1A1
Associated Variants
UGT1A1 MUTATION
UGT1A1 MUTATION
Associated Disease
Colorectal cancer metastatic
Source Database
DisGeNET
Description
To report a metastatic colorectal cancer patient with hyperbilirubinemia treated with a combination of bevacizumab and FOLFIRI (5-fluorouracil, leucovorin, and irinotecan) using uridine diphosphate glucuronosyl transferase (UGT1A1) genotyping.
Pubmed
24642571
Section of the abstract supporting the evidence
OBJECTIVE
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0078718142903288
Drugs