intermittent claudication

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Information
Disease name
intermittent claudication
Disease ID
DOID:3669
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT02051088 Active, not recruiting N/A Swedish Drug-elution Trial in Peripheral Arterial Disease November 2014 December 2024
NCT02276937 Active, not recruiting Phase 2 Randomized Phase IIb Trial of DVC1-0101 October 2014 August 2024
NCT02924857 Active, not recruiting N/A The Chocolate Touch Study July 26, 2017 December 2026
NCT05029739 Active, not recruiting N/A An E-health Intervention for Patients With Peripheral Artery Disease October 12, 2021 December 2024
NCT00071266 Completed Phase 3 The Dose Response of Niacin ER/Lovastatin on Peak Walking Time (PWT) in Patients With Intermittent Claudication - TROPIC October 2003
NCT00080392 Completed Phase 1 EW-A-401 to Treat Intermittent Claudication March 27, 2004 December 29, 2011
NCT00102050 Completed Phase 2 Efficacy and Safety of NM-702 Tablets for the Treatment of Intermittent Claudication April 2003 April 2006
NCT00117650 Completed Phase 2 Safety and Efficacy Study of Ad2/Hypoxia Inducible Factor (HIF)-1α/VP16 Gene Transfer in Patients With Intermittent Claudication February 2005 March 2010
NCT00118560 Completed N/A Exercise Training for Patients With Poor Leg Circulation June 2005 December 2007
NCT00134277 Completed N/A Trial Comparing Different Medical Devices for Infragenual Dilatation September 2004 April 2010
NCT00152737 Completed Objective Evaluation of Proximal Ischemia March 2004 July 2008
NCT00153166 Completed Phase 2/Phase 3 ARREST PAD (Peripheral Arterial Disease) January 2004 December 2011
NCT06167265 Completed Phase 1 BE Study of Once Daily PMR Compared to Twice Daily Cilostazol Tablets in Healthy Volunteers November 28, 2023 January 18, 2024
NCT00262561 Completed Phase 4 Resistance to Aspirin and/or Clopidogrel Among Patients With PAD. January 2006 January 2008
NCT06046196 Completed Phase 4 Clinical Trial to Evaluate the Efficacy and Safety of Sarpogrelate SR in Patients With Chronic Artery Occlusive Disease November 18, 2020 March 9, 2023
NCT00300339 Completed Phase 2 Mixed Antagonist of Serotonin for Claudication Optimal Therapy February 2006 December 2007
NCT00300690 Completed Phase 4 Choice of Material for Above-Knee Femoro-Popliteal Bypass Prosthetic Graft (PopUp) October 1993 January 1999
NCT00352222 Completed Phase 3 Safety and Efficacy of Express LD to Treat Stenosed or Occlusive Atherosclerotic Disease in Iliac Arteries January 2004 February 2007
NCT00388128 Completed Phase 3 Caffeine and Intermittent Claudication September 2006 September 2009
NCT00399919 Completed Phase 3 Safety and Efficacy of Propionyl-L-Carnitine in the Treatment of Peripheral Arterial Disease (Intermittent Claudication) April 2006 March 2008
NCT00403494 Completed Phase 2 A Phase 2 Study of the Effects of Sapropterin Dihydrochloride on Symptomatic Peripheral Arterial Disease December 2006 January 2009
NCT05466734 Completed Phase 1 BE Study of Once Daily PMR Compared to Twice Daily Cilostazol IR Tablets in Healthy Volunteers July 5, 2022 September 20, 2022
NCT05260567 Completed N/A Telehealth Exercise Training in Peripheral Arterial Disease - TEXT-PAD February 5, 2022 November 8, 2023
NCT00443287 Completed Phase 2 Efficacy and Safety of HMR1766 in Patients With Fontaine Stage II Peripheral Arterial Disease February 2007 October 2008
NCT00459446 Completed Phase 1 Imaging of Totally Blocked Arteries April 5, 2007
NCT00523263 Completed Phase 3 Dacron vs Dardik for Fem-Pop Bypass January 1996 April 2007
NCT00029991 Completed Phase 1/Phase 2 Extract of Ginkgo Biloba (EGB 761) and Vascular Function September 2000 July 2005
NCT05126680 Completed N/A Moderate Intensity Functional Training as Adjuvant Treatment in Patients With Peripheral Arterial Disease November 19, 2021 June 30, 2023
NCT05059899 Completed N/A Home-based Circuit Training for People With Intermittent Claudication May 9, 2022 June 26, 2023
NCT00556101 Completed Patient Acceptance of Whole Body Magnetic Resonance Angiography November 2007 July 2009
NCT00560534 Completed Whole Body Magnetic Resonance Angiography With Subsystolic Venous Compression June 2008 March 2009
NCT00602173 Completed N/A Bioequivalency Study of 100 mg Cilostazol Tablets Under Fasting Conditions May 2003 May 2003
NCT00602407 Completed N/A Bioequivalency Study of 50 mg Cilostazol Tablets Under Fasting Conditions February 2004 March 2004
NCT00618670 Completed N/A Home-based vs. Supervised Exercise for People With Claudication September 2006 September 2016
NCT00637741 Completed Phase 4 DURABILITY-200: EverFlex 200mm Long Nitinol Stents in TASC C&D Femoropopliteal Lesions March 2008 November 2010
NCT00654810 Completed N/A Exercise Rehabilitation of Younger and Older People With Claudication February 1994 January 2000
NCT00660634 Completed Phase 4 Angioplasty in Peripheral Arterial Disease and Endothelial Function December 2004 April 2008
NCT00667290 Completed N/A Exercise for Elderly Peripheral Revascularized Patients July 2000 June 2007
NCT00673985 Completed N/A Edwards Lifesciences Self-Expanding Stent Peripheral Vascular Disease Study July 2004 October 2010
NCT00692276 Completed N/A Investigating Superion™ In Spinal Stenosis June 2008 February 2017
NCT00715416 Completed Phase 4 PTA vs. Primary Stenting of SFA Using Self-Expandable Nitinol Stents June 2004 February 2008
NCT00725881 Completed Phase 1/Phase 2 Safety, Efficacy, and Pharmacokinetics (PK) Study of Trans Sodium Crocetinate (TSC) in Patients With Intermittent Claudication August 2008 March 2010
NCT00764777 Completed Phase 4 Efficacy Study of Iliac Stents to Treat TASC A-B-C-D Iliac Artery Lesions December 2008 December 2012
NCT00773630 Completed Phase 1 A Mono-center Study in Healthy Volunteers on the Comparative Bioavailability of Pletal 100 mg Tablets and a New Pletal 100 mg Orodispersible Tablet (ODT), This Latter in Fasting Conditions With and Without Water and Under Fed Conditions December 2008 March 2009
NCT00783081 Completed Phase 2 Safety and Efficacy of K-134 for the Treatment of Intermittent Claudication November 2008 July 2010
NCT00798850 Completed N/A Trial of Nonsurgical Treatment of Intermittent Claudication Due to Femoro-popliteal Disease August 2002 November 2010
NCT00822172 Completed Phase 4 Evaluation of Cilostazol in Combination With L-Carnitine September 2008 December 2010
NCT00834548 Completed Whole-Body MRA at 3T - A Comparison Between Two Different Scan Protocols June 2008 August 2008
NCT00895635 Completed Phase 3 Evaluating Two Exercise Training Programs to Reduce Leg Pain in People With Peripheral Arterial Disease (The EXERT Study) January 2009 April 2014
NCT00946868 Completed Prevalence of Metabolic Syndrome in Patients With Intermittent Claudication May 2009 July 2009
NCT03446027 Completed N/A Does Neuromuscular Electrical Stimulation Improve the Absolute Walking Distance in Patients With Intermittent Claudication Compared to Best Available Treatment? February 16, 2018 September 30, 2021
NCT03283358 Completed N/A Person-centered Follow up and Health Promotion Program After Revascularization for Intermittent Claudication June 13, 2016 May 31, 2020
NCT00062556 Completed Phase 3 Effect of Niacin ER/Lovastatin on Peak Walking Time & Claudication Onset Time in Patients With Intermittent Claudication January 2003 March 2006
NCT00068133 Completed Phase 2 Trial of VLTS-589 in Subjects With Intermittent Claudication June 2003 June 2005
NCT00032357 Completed Phase 3 Does the Reduction of Total Body Iron Storage (TBIS) Alter Mortality in a Population of Patients With Advanced PVD? May 1999 September 2005
NCT03071146 Completed Utility, Safety, and Effectiveness of the Bard LifeStent 5F Vascular Stent System February 15, 2017 May 31, 2018
NCT03204825 Completed N/A Pain Management and Patient Education for Physical Activity in Intermittent Claudication (PrEPAID) August 1, 2017 March 24, 2020
NCT03271710 Completed N/A Study to Evaluate the Lower Extremity Intervention With Integrated Embolic Protection Using the Vanguard IEP System September 1, 2017 December 30, 2018
NCT01131013 Completed Phase 2 A Study of CK-2017357 in Patients With Peripheral Artery Disease and Symptomatic Claudication May 2010 March 2011
NCT04853719 Completed Phase 4 Rivaroxaban 2.5 mg BID and Aspirin for Intermittent Claudication in PAD Patients April 20, 2021 February 1, 2023
NCT01219842 Completed N/A Invasive Revascularization or Not in Intermittent Claudication March 2010 June 2020
NCT01256775 Completed Phase 2 Effect of NCX4016 on Walking Distance in Patients With Peripheral Arterial Occlusive Disease (PAOD) September 2003 April 2005
NCT04390282 Completed N/A Secondary Prevention and Application-based Lifestyle Support for Patients With Intermittent Claudication September 1, 2021 February 28, 2022
NCT01484509 Completed Subjective and Objective Methods of Assessing Walking Limitation Due to Claudication June 2011 May 2012
NCT01679990 Completed Phase 2 Safety and Efficacy of Allogeneic Cells for the Treatment of Intermittent Claudication(IC) November 5, 2012 February 9, 2019
NCT01774097 Completed Phase 2 Patients With Intermittent Claudication Injected With ALDH Bright Cells June 2013 March 2017
NCT04376099 Completed Focus on Analysis of Recovery in Oximetry January 1, 2018 December 31, 2019
NCT01822457 Completed N/A Effect of Nike FuelBand on Exercise and Function in Claudicants; a Randomised Controlled Trial August 2013 August 2016
NCT01842412 Completed The Initial Effect of Training on Mitochondrial Function in Patients With Intermittent Claudication April 2013 May 2014
NCT01890135 Completed Phase 2 Zibotentan, an Endothelin Receptor Antagonist, Patients With Intermittent Claudication June 2013 June 2016
NCT04043546 Completed N/A Observational Feasibility Study of Home-based Training With Therabands in PAD-patients October 1, 2017 September 30, 2018
NCT02041169 Completed N/A Lower Extremity Peripheral Arterial Disease and Exercise Ischemia September 2014 September 2018
NCT02097082 Completed N/A Treatment of SFA Lesions With 480 Biomedical STANZA™ Drug-Eluting Resorbable Scaffold (DRS) System October 2013 May 2017
NCT03898570 Completed Distributed Registry April 1, 2019 March 1, 2021
NCT03864666 Completed Phase 1 Bioequivalence Study of Once Daily PMR Compared to Twice Daily Cilostazol IR Tablets in Healthy Volunteers February 11, 2019 May 3, 2019
NCT02310256 Completed N/A A Clinical Trial on the Effects of Home-based Five Plus Exercise Training November 2014 March 2016
NCT03640676 Completed N/A Intermittent Negative Pressure to Improve Blood Flow in Patients With Peripheral Artery Disease: Effects After Long-term Treatment January 14, 2019 January 31, 2020
NCT02380794 Completed Phase 2 Novel Treatment of Intermittent Claudication in Patients With Peripheral Arterial Disease Using Danshen Gegen (D&G) Capsule October 28, 2015 June 2, 2017
NCT02429310 Completed N/A Adjuvant Benefit of NMES to Supervised Exercise in Patients With IC December 2014 October 2016
NCT02434783 Completed The Relationship Between Peripheral Arterial Disease and Mitochondrial Respiratory Capacity May 2015 April 2016
NCT02436200 Completed N/A Neuromuscular Electrical Stimulation (NMES) in Patients With Intermittent Claudication December 2014 October 2015
NCT02505503 Completed N/A York Study of Unloading Shoes for Vascular Intermittent Claudication July 2015 September 2016
NCT03564080 Completed N/A Assessing the Feasibility of Including Patients With Peripheral Artery Disease in to an Established Cardiac Rehabilitation Service. July 18, 2018 September 11, 2022
NCT02607046 Completed N/A Exercise Rehabilitation in Veterans With PAD October 1, 2015 December 20, 2023
NCT02641418 Completed N/A Optimising the Efficacy, Patient Perception and Uptake of an Exercise Programme in People in Intermittent Claudication May 2015 October 2017
NCT02642276 Completed N/A Exercise Training in Individuals With Peripheral Arterial Disease June 2015 April 2017
NCT02778568 Completed N/A Acute Cardiovascular Responses and Chronic Adaptations of Strength Exercise in Intermittent Claudication Patients January 2010 December 2015
NCT02823444 Completed Non-Contrast Enhanced Peripheral Magnetic Resonance Angiography April 2008 June 30, 2018
NCT03547817 Completed N/A Intermittent Negative Pressure to Improve Blood Flow in Patients With Peripheral Artery Disease: Optimal Pulse Pressure Regime May 15, 2018 January 31, 2019
NCT03511157 Completed N/A Ischemic Preconditioning Claudication Study June 14, 2018 December 13, 2022
NCT02897947 Completed Outcome of Surgery for Lumbar Spinal Stenosis - a Comparison of Data From Three National Quality Registries January 2011 June 2015
NCT02927574 Completed Systematic Review and Meta-Analysis on DCB vs. POBA in De-novo Femoropopliteal Disease July 2016 September 2017
NCT03480321 Completed Phase 1 Pharmacokinetic Study of Once Daily PMR Compared to Twice Daily Cilostazol IR Tablets in Healthy Volunteers March 6, 2018 June 7, 2018
NCT05611021 Enrolling by invitation N/A Acute Responses to Arm-Crank Exercise on Cardiovascular Function of Patients With Peripheral Artery Disease June 8, 2022 December 20, 2024
NCT05335161 Not yet recruiting Phase 1 A New Heat Therapy Device for Home-based Leg Heating in Patients With Lower-extremity Peripheral Artery Disease September 1, 2022 January 31, 2024
NCT06410521 Not yet recruiting N/A Personalised Multicomponent Exercise Programme in Peripheral Arterial Disease May 2024 December 2027
NCT06186505 Not yet recruiting N/A Heat Therapy for Peripheral Arterial Disease (HEATPAD) January 1, 2025 December 31, 2028
NCT05132439 Recruiting Phase 3 MetfOrmin BenefIts Lower Extremities With Intermittent Claudication March 1, 2022 February 28, 2031
NCT03048890 Recruiting VascTrac Peripheral Arterial Disease (PAD) Study March 1, 2017 December 1, 2023
NCT04042311 Recruiting N/A High Intensity Interval Training In pATiEnts With Intermittent Claudication June 15, 2018 December 28, 2022
NCT04370327 Recruiting N/A The Effects of Claudication Severity on Functional Outcomes July 5, 2021 January 2025
NCT04749732 Recruiting N/A Home-based Exercise Therapy for Patients With PAD February 9, 2021 November 30, 2023
NCT05400395 Recruiting Phase 4 Clinical Trial for GNX80 in Intermittent Claudication September 5, 2022 August 2024
NCT05457738 Recruiting N/A Home-based Exercice Therapy for Patients With Intermittent Claudication Using a New Smartphone Application April 19, 2024 November 19, 2025
NCT05773534 Recruiting Calf Muscle Perfusion in Patients With Intermittent Claudication by 3D-reconstruction of MSOT (MSOT_IC_3D) February 27, 2022 May 31, 2023
NCT06114732 Recruiting N/A Motivating Physical Activity With Behavioural interVention and Electrical Stimulation Remotely in Intermittent Claudication January 29, 2024 December 1, 2025
NCT06299956 Recruiting N/A Supervised Exercise-based Rehabilitation for People With Intermittent Claudication in Denmark September 1, 2023 January 2029
NCT06391346 Recruiting N/A Investigation of the Perfusion of Gluteal Muscle in Patients With Intermittent Gluteal Claudication by Non-invasive MSOT June 23, 2023 April 2024
NCT00554073 Suspended Whole Body Magnetic Resonance Angiography in Ischemic Patients at 1.5 and 3T May 2008 August 2009
NCT02152930 Terminated Phase 3 The Effects of Fish Oil Supplements During Supervised Exercise Therapy in Patients With Intermittent Claudication December 2014 February 2016
NCT00437905 Terminated Phase 4 Balloon Angioplasty vs. Cutting Balloon Angioplasty of Femoropopliteal Arteries- a Randomized Controlled Trial June 2003 January 2007
NCT01799057 Terminated Phase 4 The Effects of Metformin on Functional Capacity in Individuals With Peripheral Artery Disease-Related Intermittent Claudication July 2013 December 2014
NCT01385774 Terminated N/A SUPER Study; SUPERvised Exercise or Angioplasty for Intermittent Claudication Due to an Iliac Artery Obstruction. November 2010 May 2016
NCT05191862 Terminated Phase 1 Bioequivalence Study of Once Daily PMR Compared to Twice Daily Cilostazol IR Tablets in Healthy Volunteers April 23, 2022 May 7, 2022
NCT04100681 Terminated N/A Intermittent Negative Pressure; Impact on Peripheral Artery Disease and Intermittent Claudication August 19, 2019 May 31, 2020
NCT00111826 Terminated Phase 3 SIMPADICO - Study of Immune Modulation Therapy in Peripheral Arterial Disease and Intermittent Claudication Outcomes January 2003 December 2005
NCT01177033 Unknown status Angioplasty or Bypass Surgery in Intermittent Claudication August 2010 December 2014
NCT01007604 Unknown status Phase 2 Treatment of Claudication With a Peristaltic Pulse Pneumatic Device November 2009 March 2011
NCT00539266 Unknown status Phase 2/Phase 3 Autologous Bone Marrow-derived Mononuclear Cells for Therapeutic Arteriogenesis in Patients With Limb Ischemia October 2007 October 2012
NCT00538408 Unknown status Whole Body Magnetic Resonance Angiography in Ischemic Patients September 2007 January 2010
NCT05232474 Unknown status N/A Using KomPas+ in the Treatment of Patients With Intermittent Claudication October 1, 2022 February 28, 2024
NCT03730623 Unknown status N/A Cross-sectoral Rehabilitation for Patients With Intermittent Claudication December 5, 2017 September 2020
NCT03837639 Unknown status N/A Arm-crank Exercise Training on Cardiovascular Function of Patients With Peripheral Artery Disease June 10, 2019 December 10, 2023
NCT03909022 Unknown status Assessing Best Medical Treatment Patterns of Patients With Symptomatic Peripheral Arterial Occlusive Disease in Germany January 1, 2008 April 1, 2021
NCT01980602 Unknown status N/A Effect of Exercise on Patients With Claudication Undergoing Surgery March 2011
NCT04168021 Unknown status N/A Remote Ischemic Conditioning of the Human Brain in Dementia Patients January 1, 2020 December 31, 2021
NCT00146666 Unknown status Phase 2 Evaluation of FM220 in Patients With Peripheral Arterial Disease (PAD) September 2005 September 2006
NCT04586725 Unknown status N/A Effect of Encouragement on Six Minute Walk Test Performance October 1, 2021 January 1, 2024
NCT00279994 Unknown status N/A (Cost) Effectiveness Study of Exercise Therapy in Patients With Peripheral Arterial Disease December 2005 May 2009
NCT02510807 Unknown status N/A The PaWS (Pedometer and Walking Study) July 2015 July 2017
NCT02341716 Unknown status N/A Hospital- and Home-based Supervised Exercise Versus UNsupervised Walk Advice For Patients With InTermittent Claudication September 2014 June 2022
NCT03683628 Unknown status N/A Treatment of Intermittent Claudication by G-CSF-mobilized PB-MNC October 1, 2018 December 31, 2023
NCT03784729 Unknown status N/A Efficacy of Acupuncture for Lumbar Spinal Stenosis March 25, 2019 December 31, 2020
NCT00424866 Unknown status Phase 1/Phase 2 FGF-1 for Intramuscular Injection for the Treatment of Peripheral Arterial Disease December 2020 June 2022
NCT05373927 Unknown status Calf Muscle Perfusion in Patients With Intermittent Claudication by Non-invasive MSOT June 20, 2022 September 30, 2022
NCT00251849 Unknown status Phase 3 PROVIDENCE-1: Study of Rifalazil in Chlamydia Pneumoniae Seropositive Patients November 2005 December 2007
NCT00351286 Unknown status Phase 2 Efficacy Study of Oral L-Citrulline in Patients Taking Simvastatin With Peripheral Arterial Disease March 2006
NCT03238222 Unknown status N/A Motivating Structured Walking Activity in Intermittent Claudication November 10, 2017 January 9, 2021
NCT02993874 Unknown status N/A Creatine Supplementation in Patients With Intermittent Claudication. June 26, 2017 June 2019
NCT03512912 Unknown status Transcutaneous Electrostimulation for Intermittent Claudication Supervised Walking Therapy for Intermittent cLAudication May 2018 May 2020
NCT02878954 Unknown status N/A Exercise in Peripheral Artery Disease January 2017 December 2019
NCT05618691 Withdrawn Phase 2 A Study of GFH312 in Patients With Peripheral Artery Disease (PAD) and Intermittent Claudication (IC) December 1, 2022 May 31, 2024
NCT02879019 Withdrawn N/A Walking Training in Peripheral Artery Disease (GrEnADa Sub-study) November 2017 October 2019
NCT00407940 Withdrawn Phase 4 ATHERO: Advanced Technology Halting Early Re-Stenosis and Occlusion December 2006 October 2007
NCT02121288 Withdrawn Phase 4 Adenosine-induced Myocardial Blood Flow in Peripheral Artery Disease Patients December 2014 February 2016
Disase is a (Disease Ontology)
DOID:2349
Cross Reference ID (Disease Ontology)
ICD10CM:I73.9
Cross Reference ID (Disease Ontology)
MESH:D007383
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:195312007
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0021775
Exact Synonym (Disease Ontology)
Charcot's syndrome
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0004417
MeSH unique ID (MeSH (Medical Subject Headings))
D007383