nephrolithiasis

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Information
Disease name
nephrolithiasis
Disease ID
DOID:585
Description
"A kidney disease characterized by the formation of stoney concentrations in the kidneys." [url:https\://ghr.nlm.nih.gov/condition/kidney-stones, url:https\://medlineplus.gov/kidneystones.html, url:https\://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518455/]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04495608 Active, not recruiting Phase 2 Multicenter, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Fluconazole in Hypercalcicuric Patients With Increased 1.25(OH) 2D Levels January 13, 2021 July 2024
NCT05081960 Active, not recruiting Evaluating the Vitamin K2 Status of Calcium-based Stone Formers August 1, 2022 October 2023
NCT02028559 Active, not recruiting N/A Safety and Effectiveness of the Ultrasonic Propulsion of Kidney Stones January 2014 June 2024
NCT00169780 Completed Kidney Stone Structural Analysis By Helical Computed Tomography (CT) July 2002 August 2011
NCT00169793 Completed N/A Nephrolithiasis and Bariatric Surgery August 2005 December 2012
NCT00226564 Completed N/A Genetic Determinants of Opioids Analgesia August 1997
NCT00263107 Completed Postoperative Telerounding: A Multi-Center Prospective Randomized Assessment of Patient Outcomes and Satisfaction. August 2004 June 2005
NCT00587041 Completed Phase 1/Phase 2 Use of Oral Probiotics to Reduce Urinary Oxalate Excretion February 2006 July 2009
NCT00600405 Completed N/A The Efficacy of Tamsulosin in the Treatment of Ureteral Stones in Emergency Department Patients August 2006 November 2007
NCT05845281 Completed N/A Comparison of Erector Spinae Plane Block and Intravenous Patient-controlled Analgesia in Percutaneous Nephrolithotomy February 2, 2022 March 20, 2023
NCT01217372 Completed Phase 2 Nephrolithiasis Prevention by Lemon Juice January 2009 February 16, 2021
NCT01295879 Completed Phase 4 Vitamin D Repletion in Stone Formers With Hypercalciuria September 2010 June 2011
NCT01300039 Completed Oral Antibiotic Treatment of Helicobacter Pylori Reduces Intestinal Colonization Rates With Oxalobacter Formigenes January 2003 June 2008
NCT01330940 Completed N/A Effect of Diet Orange Soda on Urinary Lithogenicity November 2009 July 2010
NCT05808257 Completed N/A Thulium vs. Hol:YAG Laser January 7, 2022 February 1, 2024
NCT01619735 Completed "Dusting" Versus "Basketing" - Treatment Of Intrarenal Stones April 2013 June 10, 2017
NCT01650935 Completed N/A Comparison of DASH With Oxalate Restricted Diet on Urine in Recurrent Stone Formers With Hyperoxaluria September 2012 April 2013
NCT01690039 Completed Influence of Polymorphisms in the ATP6V1 Gene of the V-ATPase on the Development of Incomplete Distal Renal Tubular Acidosis September 2012 May 12, 2017
NCT03584373 Completed Phase 3 Pain Outcomes of Non-opioid vs. Opioid Analgesia for Kidney Stone Surgery. July 27, 2018 March 23, 2022
NCT00169663 Completed Brushite Kidney Stones: A Registry and Database of Clinical and Laboratory Findings July 2003 November 2010
NCT03774940 Completed N/A Blood Parameters as a Predictor of Fever After Percutaneous Nephrolithotomy January 1, 2005 January 31, 2014
NCT03349099 Completed N/A Impact Ureteral Sheath Design During Ureteroscopy June 27, 2014 July 2016
NCT03379922 Completed N/A Strategies to Maximise Patient Comfort During ESWL March 27, 2017 December 12, 2018
NCT03454139 Completed N/A Subcostal TAP Block For Percutaneous Nephrolithotomy October 2015 September 2017
NCT03461536 Completed N/A Ultrasound First Clinical Decision Support for Suspected Nephrolithiasis January 2, 2019 December 19, 2019
NCT03927781 Completed Phase 3 Perioperative Pregabalin in Ureteroscopy: a Pilot April 1, 2019 October 17, 2020
NCT02095665 Completed Phase 4 Ureteral Stent-related Pain and Mirabegron (SPAM) Trial January 1, 2014 March 23, 2018
NCT02188108 Completed N/A Validation of the Wisconsin Stone-QOL July 2014 June 30, 2023
NCT02276924 Completed N/A Diagnostic Relevance of Laser Confocal Microscopy for the Screening of Upper Urinary Tract Tumors October 2013 October 2016
NCT05525130 Completed N/A Study of the Administration of a Food Supplement in Patients With Lithiasis Treated With Extracorporeal Shock Wave Lithotripsy. April 22, 2020 October 5, 2022
NCT02289755 Completed Phase 2 Evaluating ALLN-177 for Reducing Urinary Oxalate Excretion in Calcium Oxalate Kidney Stone Formers With Hyperoxaluria September 2014 February 2015
NCT02384200 Completed Phase 4 A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Kidney Stone Surgery (Percutaneous Nephrolithotomy [PCNL]) March 2015 June 1, 2019
NCT05350423 Completed N/A Trial Assessing Renal Damage During Ureteroscopy October 22, 2021 November 28, 2022
NCT05153629 Completed N/A Noninvasive Electrical Stimulator as a Pain Control Treatment Post-ureteroscopy January 10, 2021 October 1, 2023
NCT02457494 Completed Kidney Stone Risk Factors in Patients Infected With HIV May 2015 March 2018
NCT02503345 Completed Phase 2 Evaluate the Effect of ALLN-177 in Reducing Urinary Oxalate in Patients With Hyperoxaluria and Kidney Stones July 2015 January 2017
NCT02547805 Completed Phase 2 Evaluate the Effect of ALLN-177 in Reducing Urinary Oxalate in Patients With Secondary Hyperoxaluria and Kidney Stones Over 28 Days September 2015 January 2017
NCT00159393 Completed Percutaneous Nephrolithotomy: A Registry and Database October 2003 December 2018
NCT04998435 Completed N/A Paravertebral Block Versus Erector Spinae Plain Block In Percutaneous Nephrolithotomy August 11, 2021 January 1, 2022
NCT02878148 Completed N/A Conditional Imaging Prescription Strategy for Exploration of Acute Uncomplicated Renal Colic October 17, 2016 February 22, 2018
NCT02938884 Completed N/A Hidrate Me Smart Water Bottle Use in Patient With Nephrolithiasis December 5, 2016 January 31, 2021
NCT04869462 Completed DS Titanium Ligation Clip in Urology (Prostatectomy and Nephrectomy) May 27, 2021 January 29, 2022
NCT03035812 Completed Phase 4 Alkalinization by Urologists & Nephrologists February 1, 2017 February 21, 2020
NCT03057431 Completed Phase 3 Hydrochlorothiazide for Kidney Stone Recurrence Prevention March 9, 2017 April 30, 2022
NCT04597619 Completed N/A Evaluation of a Nonopioid Recovery Pathway Following Surgery for Kidney Stones December 1, 2020 June 11, 2022
NCT03087149 Completed N/A Monitored vs Standard Supplementation of Vitamin D in Preterm Infants May 1, 2017 March 31, 2020
NCT04556396 Completed N/A Intraoperative Cone-beam CT for Percutaneous Nephrolithotomy June 25, 2020 May 1, 2022
NCT03095885 Completed N/A A Pilot Study of Oxalate Absorption in Secondary Hyperoxaluria November 2016 March 2017
NCT04505956 Completed N/A A Comparison of Ureteroscopic Treatment of Nephrolithiasis With and Without Moses Technology January 13, 2021 December 1, 2023
NCT04299204 Completed N/A The Success of Pediatric Percutaneous Nephrolithotomy January 15, 1998 July 1, 2018
NCT03332056 Completed Phase 4 The Use of Belladonna and Opium Suppository in the Treatment of Postoperative Stent Pain August 2013 October 2015
NCT04285658 Completed Pediatric KIDney Stone (PKIDS) Care Improvement Network April 2, 2020 January 31, 2024
NCT03348228 Completed N/A Effect of Hydroxycitrate on Urine Chemistry October 4, 2018 December 15, 2020
NCT04746378 Enrolling by invitation PRedictive Accuracy of Initial Stone Burden Evaluation. September 9, 2021 December 31, 2028
NCT06266793 Enrolling by invitation N/A Comparison of Holmium Laser and Thulium Laser for Mini PCNL March 7, 2024 June 1, 2027
NCT06149455 Not yet recruiting N/A Preoperative Prophylactic Antibiotic Duration in Moderate to High Risk Ureteroscopy January 1, 2024 January 1, 2026
NCT02214836 Not yet recruiting N/A Ultrasound Imaging of Kidney Stones and Lithotripsy October 1, 2024 December 2025
NCT06199102 Not yet recruiting N/A The High Initial Dose of Monitored Vitamin D Supplementation in Preterm Infants. September 1, 2024 December 31, 2027
NCT06331546 Recruiting N/A Gut Oxalate Absorption in Calcium Oxalate Stone Disease April 17, 2024 December 31, 2031
NCT02829060 Recruiting N/A Endourology Disease Group Excellence (EDGE) Consortium: Antibiotics (Abx) for Percutaneous Nephrolithotomy (PCNL) Part 2 January 2016 January 2025
NCT03692715 Recruiting Phase 4 Antibiotic Prophylaxis Before Shock Wave Lithotripsy September 27, 2018 December 31, 2024
NCT04389853 Recruiting N/A Mini-PNCL vs fURS in Management of Nephrolithiasis October 5, 2020 December 31, 2025
NCT04669886 Recruiting Serum Endotoxin Assay to Predict the Development of Postoperative Infectious Complications and Systemic Inflammatory Response Following Percutaneous Nephrolithotomy. November 1, 2023 September 1, 2025
NCT04726345 Recruiting Phase 2 Effect of Antihistamines on Ureteral Stent-Related Symptoms June 29, 2021 June 30, 2024
NCT05014178 Recruiting Kidney Sodium Functional Imaging September 16, 2021 December 31, 2024
NCT05100017 Recruiting N/A Methocarbamol vs Oxybutynin for Management of Pain and Discomfort S/P Ureteroscopy Procedure September 30, 2021 September 2024
NCT05237063 Recruiting N/A Prediction of Recurrence and Complications of Nephrolithiasis Using a Precision Medicine Approach January 13, 2021 February 2031
NCT05365477 Recruiting Phase 4 Empiric Versus Selective Prevention Strategies for Kidney Stone Disease August 4, 2022 March 31, 2025
NCT05701098 Recruiting N/A SOUND Pivotal Trial - (Sonomotion stOne comminUtion resoNance ultrasounD) October 9, 2023 January 2025
NCT05872230 Recruiting N/A Massage Percussion for Passage of Urolithiasis Fragments After Ureteroscopy. February 1, 2024 December 2025
NCT05924165 Recruiting Phase 4 Narcotic-Free Percutaneous Nephrolithotomy May 19, 2023 June 2025
NCT06269783 Recruiting N/A Dual-process Mechanisms of Action for sipIT Intervention Effects in Patients With Urolithiasis January 10, 2024 December 31, 2024
NCT06330246 Recruiting N/A O. Formigenes Colonization in Calcium Oxalate Kidney Stone Disease April 17, 2024 December 31, 2031
NCT01371422 Terminated N/A Trial Comparing the Effect of a Paravertebral Block on Pain Post Percutaneous Nephrolithotomy August 2011 November 2013
NCT03656913 Terminated N/A Validation of Low Dose CT for Diagnosis of Urolithiasis November 30, 2018 September 28, 2020
NCT00638482 Terminated Phase 2/Phase 3 Dose-Dependent Effect of Thiazide in Dent's Disease Hypercalciuria July 2003 December 2005
NCT00149305 Terminated Genetic Study of Nephrolithiasis in Gouty Diathesis May 2005 May 2010
NCT02837393 Terminated Understanding the Urine Electrolyte Profile of the Individual Renal Unit July 2016 April 1, 2017
NCT00860093 Terminated Phase 2 Efficacy and Safety of Using MPC-5971 in Subjects Undergoing Shock Wave Lithotripsy April 2010 December 2010
NCT02443909 Unknown status Phase 4 Comparison of Safety and Efficiency of 20w and 30w Holmium Laser Device in Management of 2-3 cm Diameter Kidney Stones With Retrograde Intrarenal Surgery January 2015 January 2017
NCT05270421 Unknown status Phase 3 Effect of Furosemide on ESWL Outcomes for Renal and Ureteral Calculi July 1, 2020 July 30, 2022
NCT02430883 Unknown status Phase 4 Is There Any Relation Between Pain and Stone Location in Retrograde Intrarenal Surgery? January 2015 January 2016
NCT03229889 Unknown status Phase 4 Trial of Tadalafil, Tamsulosin and Combination for Access Sheath Deployment June 7, 2017 April 2022
NCT03092908 Unknown status N/A Mature Vinegar Prophylaxis Against Recurrent Calcium Oxalate Nephrolithiasis March 22, 2017 December 31, 2022
NCT02986997 Unknown status Over 2000 Epidural Anesthesias for Percutaneous Nephrolithotomy - a Retrospective Analysis December 2016 September 2017
NCT02966236 Unknown status Phase 4 Impact of Tranexamic Acid Use in Percutaneous Nephrolithotomy June 2016 June 2019
NCT02451319 Unknown status Phase 4 Comparison of Safety and Efficiency of 20w 30w Holmium Laser Device in Treatment of 1-2 cm Diameter Kidney Stones With RIRS January 2015 January 2017
NCT00409227 Unknown status Phase 2 Does Treatment With Alfuzosin Increase Success Rates of (SWL) Shock Wave Lithotripsy December 2006
NCT02279927 Unknown status N/A Prospective Comparison Between Different Laser Settings for Ureteral \ Kidney Stones Treatment During Ureteroscopy October 2014 December 2015
NCT03102086 Unknown status The Association Between Nephrolithiasis and Periodontal Status May 11, 2017 January 2019
NCT03951558 Unknown status N/A Comparison of the Impact of Diet vs Thiazide in BMD in Children With Idiopathic Hypercalciuria May 11, 2018 June 30, 2020
NCT04153461 Unknown status N/A Mini- Percutaneous Nephrolithotomy Versus Standard Percutaneous Nephrolithotomy in the Treatment of Renal Stones. May 1, 2019 May 1, 2021
NCT04169165 Unknown status Patient Compliance for Metabolic Evaluation and Medical Management in Calcium Stone Patients January 2020 February 2021
NCT03346369 Unknown status Phase 3 Lanthanum Carbonate (Fosrenol®) to Reduce Oxalate Excretion in Patients With Secondary Hyperoxaluria and Nephrolithiasis August 18, 2017 December 31, 2022
NCT04286152 Unknown status Phase 3 Mirabegron And Ureteral Stent-related Pain (MAP) Trial February 3, 2020 June 30, 2021
NCT03307096 Unknown status N/A Evaluation of Two Different Treatments for Lower Pore Renal Stone: Microperc Vs FURS November 17, 2017 December 31, 2019
NCT04346485 Unknown status N/A Comparison of SP TFL and Ho:YAG for RIRS Using 145 µm and 200 µm Fibers March 13, 2020 May 31, 2022
NCT04367155 Unknown status N/A Efficacy of Tranexamic Acid on Blood Loss During Percutaneous Nephrolithotomy. September 1, 2019 March 1, 2022
NCT04374188 Unknown status N/A Efficacy of Ciprofloxacin Therapy in Avoidance of Sepsis in Patient Undergoing Percutanous Nephrolithotomy September 1, 2019 March 1, 2022
NCT00948740 Withdrawn Phase 2/Phase 3 The Effect of Vitamin D on Urinary Calcium Excretion in Kidney Stone Formers With High Urinary Calcium August 2009 June 2010
NCT03058614 Withdrawn Phase 2 Contrast-enhanced Ultrasound Versus CT Scan for Kidney Stone Patient Management June 30, 2017 May 2, 2022
Disase is a (Disease Ontology)
DOID:557
Cross Reference ID (Disease Ontology)
EFO:0004253
Cross Reference ID (Disease Ontology)
ICD10CM:N20
Cross Reference ID (Disease Ontology)
ICD9CM:592
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:155867005
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0156257
Exact Synonym (Disease Ontology)
kidney stones
Exact Synonym (Disease Ontology)
Stone - kidney/ureter
HPO alt_id (Human Phenotype Ontology)
HP:0000102
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0000787
MeSH unique ID (MeSH (Medical Subject Headings))
D053040