Annotation Detail

Information
Associated Genes
UGT1A1
Associated Variants
UGT1A1 MUTATION
UGT1A1 MUTATION
Associated Disease
Colorectal cancer recurrent
Source Database
DisGeNET
Description
Previous reports of the influence of UGT1A1 gene polymorphisms on the pharmacokinetics of irinotecan metabolism have not assessed Asian patients treated with FOLFIRI plus bevacizumab for advanced and recurrent colorectal cancer.
Pubmed
24382596
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs