chr7:17171814:> Detail (hg19)

Information

Genome

Assembly Position
hg19 chr7:17,171,814-17,385,774
hg38 chr7:17,132,190-17,346,150 

HGVS

Type Transcript Protein
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

[No Data.]

Prediction

[No Data.]

ClinVar

Clinical Significance
Review star [No Data.]
Show details
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score Disease name Description Source Pubmed Links
<0.001 Carcinoma, Transitional Cell NA BeFree Detail
<0.001 Uterine Cervical Neoplasm NA BeFree Detail
<0.001 choriocarcinoma NA BeFree Detail
0.002 colitis NA BeFree Detail
<0.001 ulcerative colitis NA BeFree Detail
0.002 Colorectal Neoplasms NA GAD Detail
<0.001 dermatitis NA BeFree Detail
<0.001 Dermatitis, Atopic NA BeFree Detail
0.120 contact dermatitis NA CTD_human Detail
<0.001 Diabetic Angiopathies NA BeFree Detail
<0.001 Eczema NA BeFree Detail
<0.001 Experimental Autoimmune Encephalomyelitis NA BeFree Detail
0.008 endometriosis NA BeFree,GAD,LHGDN Detail
<0.001 Eosinophilia NA BeFree Detail
<0.001 Fatty Liver NA BeFree Detail
<0.001 glioblastoma NA BeFree Detail
<0.001 Glioma NA BeFree Detail
0.120 Growth Disorders NA CTD_human Detail
<0.001 Head and Neck Neoplasms NA BeFree Detail
0.120 congenital heart defects NA BeFree,CTD_human Detail
0.120 Cardiomegaly NA CTD_human Detail
<0.001 hepatitis NA BeFree Detail
<0.001 hepatitis A NA BeFree Detail
<0.001 hydronephrosis NA BeFree Detail
<0.001 hyperglycemia NA BeFree Detail
0.120 Hypertensive disease NA BeFree,CTD_human Detail
0.120 Hyperventilation NA CTD_human Detail
0.121 male infertility NA BeFree,CTD_human Detail
0.123 Inflammation NA CTD_human,LHGDN Detail
<0.001 Inflammatory Bowel Diseases AHR-related compounds might be the new and promising therapeutic medicaments for... BeFree 25799939 Detail
0.120 Insulin resistance NA CTD_human Detail
0.003 Laryngeal neoplasm NA BeFree,GAD Detail
0.003 Fibroid Tumor NA BeFree,LHGDN Detail
0.001 leukemia NA BeFree Detail
<0.001 Acute lymphocytic leukemia NA BeFree Detail
<0.001 Acute Megakaryocytic Leukemias NA BeFree Detail
<0.001 Myeloid Leukemia, Chronic NA BeFree Detail
0.003 Adult T-Cell Lymphoma/Leukemia NA BeFree,LHGDN Detail
0.120 Liver diseases NA CTD_human Detail
0.126 Liver neoplasms We examined the expression kinetics of some of the aryl hydrocarbon receptor (Ah... BeFree,CTD_human 25637755 Detail
0.003 Lung diseases NA LHGDN Detail
0.003 Chronic Obstructive Airway Disease NA BeFree,GAD Detail
0.005 Lung Neoplasms NA BeFree,GAD,LHGDN Detail
0.005 lymphoma NA BeFree,GAD,LHGDN Detail
0.005 Lymphoma, Non-Hodgkin NA BeFree,GAD Detail
<0.001 malaria NA BeFree Detail
0.001 Malignant neoplasm of stomach NA BeFree Detail
<0.001 medulloblastoma NA BeFree Detail
<0.001 melanoma NA BeFree Detail
<0.001 premature menopause NA BeFree Detail
0.120 Metabolic Diseases NA CTD_human Detail
0.003 multiple myeloma Collectively, these data implicate polycyclic aromatic hydrocarbons and AhR in t... BeFree,GAD 24798859 Detail
0.120 Necrosis NA CTD_human Detail
0.120 Neoplasm Invasiveness NA CTD_human Detail
0.121 Neoplasm Metastasis NA BeFree,CTD_human Detail
0.120 Neoplasms, Experimental NA CTD_human Detail
<0.001 neuroblastoma NA BeFree Detail
<0.001 Nevus NA BeFree Detail
0.002 Occupational Diseases NA GAD Detail
0.002 oligospermia NA GAD Detail
0.001 ovarian carcinoma NA BeFree Detail
<0.001 Ovarian Cysts NA BeFree Detail
0.120 Pancreatic Neoplasm NA CTD_human Detail
0.120 Peripheral neuropathy NA CTD_human Detail
0.001 pituitary adenoma Although AHR has been found differently expressed in pituitary adenomas, AHR gen... BeFree 24521362 Detail
<0.001 Pituitary Neoplasms NA BeFree Detail
0.120 pneumonia NA BeFree,CTD_human Detail
<0.001 polyps NA BeFree Detail
0.120 Prostatic Neoplasms NA CTD_human Detail
<0.001 psoriasis NA BeFree Detail
<0.001 Signs and Symptoms, Respiratory NA BeFree Detail
0.120 silicosis NA CTD_human Detail
<0.001 Dermatologic disorders NA BeFree Detail
<0.001 Sleep disturbances NA BeFree Detail
0.120 Splenic Diseases NA CTD_human Detail
0.120 Splenomegaly NA CTD_human Detail
0.123 Stomach Neoplasms NA CTD_human,LHGDN Detail
<0.001 Cerebrovascular accident L-kynurenine/aryl hydrocarbon receptor pathway mediates brain damage after exper... BeFree 25359166 Detail
0.120 Tachycardia NA CTD_human Detail
0.120 Tobacco use disorder NA CTD_human Detail
0.120 Ureteral Neoplasms NA CTD_human Detail
<0.001 Uterine Fibroids NA BeFree Detail
0.120 Vascular Diseases NA CTD_human Detail
<0.001 vitiligo NA BeFree Detail
<0.001 diffuse large B-cell lymphoma It is particularly interesting that BCL6 - regulated by AhR/ARNT and wild-type M... BeFree 25769544 Detail
<0.001 Lymphoma, Large-Cell, Follicular NA BeFree Detail
0.002 Neoplasms, Second Primary NA GAD Detail
<0.001 Ovarian Failure, Premature NA BeFree Detail
<0.001 Xeroderma Pigmentosum, Complementation Group D We assessed polymorphisms in the aryl hydrocarbon receptor (AhR-Arg554Lys), null... BeFree 15459223 Detail
0.120 Left Ventricular Hypertrophy NA CTD_human Detail
<0.001 Small cell carcinoma of lung NA BeFree Detail
<0.001 Atrophic condition of skin NA BeFree Detail
0.121 Adenocarcinoma of lung (disorder) NA BeFree,CTD_human Detail
<0.001 Secondary malignant neoplasm of lung NA BeFree Detail
0.001 Tumor Progression In conclusion AhR knockdown alters the expression of genes known to enhance or i... BeFree 24932473 Detail
<0.001 Carcinoma, Endometrioid NA BeFree Detail
<0.001 Cystadenocarcinoma, Serous NA BeFree Detail
0.002 Squamous Cell Neoplasms NA GAD Detail
<0.001 Angiofibroma NA BeFree Detail
0.120 Chronobiology Disorders NA CTD_human Detail
0.120 Dyslipidemias NA CTD_human Detail
0.010 Malignant neoplasm of lung NA BeFree,GAD Detail
0.003 age related macular degeneration Collectively, our findings identify AhR as a regulator of multiple pathogenic pa... BeFree,GAD 25186463 Detail
0.120 Hyperoxia NA CTD_human Detail
<0.001 Parasitemia NA BeFree Detail
<0.001 Chloracne NA BeFree Detail
<0.001 Chronic nonspecific lung disease NA BeFree Detail
<0.001 Xeroderma Pigmentosum, Complementation Group D NA BeFree Detail
0.120 Lung Injury NA CTD_human Detail
<0.001 Carcinoma breast stage IV NA BeFree Detail
<0.001 Liver and Intrahepatic Biliary Tract Carcinoma NA BeFree Detail
<0.001 Squamous cell carcinoma of esophagus NA BeFree Detail
<0.001 Conventional (Clear Cell) Renal Cell Carcinoma Activation of aryl hydrocarbon receptor promotes invasion of clear cell renal ce... BeFree 25523818 Detail
<0.001 laryngeal squamous cell carcinoma NA BeFree Detail
0.120 Atrophic NA CTD_human Detail
<0.001 Hyperplastic Polyp NA BeFree Detail
<0.001 Malignant neoplasm of liver NA BeFree Detail
<0.001 Growth Hormone-Secreting Pituitary Adenoma In this study, we evaluated patients with apparently sporadic GH-secreting pitui... BeFree 24521362 Detail
<0.001 Asthma attack NA BeFree Detail
0.002 Malignant neoplasm of prostate NA BeFree Detail
<0.001 Hematologic Neoplasms NA BeFree Detail
<0.001 Papillary neoplasm NA BeFree Detail
0.001 endometrial carcinoma Aryl hydrocarbon receptor exogenous ligand 3-methylchoranthrene inhibited endome... BeFree 24817304 Detail
0.002 dementia NA GAD Detail
<0.001 Metabolic syndrome X NA BeFree Detail
<0.001 Early Awakening NA BeFree Detail
0.120 Allergy to peanuts NA CTD_human Detail
0.007 Carcinogenesis Aryl hydrocarbon receptor (AHR) pathway has a key role in cellular detoxificatio... BeFree 24521362 Detail
0.007 Carcinogenesis Collectively, our results suggest that p53 affects AhR-dependent gene expression... BeFree 24736433 Detail
0.007 Carcinogenesis The present study was designed to elucidate the role of the aryl hydrocarbon rec... BeFree 25523818 Detail
<0.001 Tumor Initiation NA BeFree Detail
0.002 prostate carcinoma NA BeFree Detail
<0.001 Hot flushes NA BeFree Detail
<0.001 Epithelial ovarian cancer NA BeFree Detail
0.012 breast carcinoma Depletion of the aryl hydrocarbon receptor in MDA-MB-231 human breast cancer cel... BeFree 24932473 Detail
0.012 breast carcinoma DIM is an aryl hydrocarbon receptor (AhR) ligand and a potential anticancer agen... BeFree 25048790 Detail
0.012 breast carcinoma A novel compound, NK150460, exhibits selective antitumor activity against breast... BeFree 25522763 Detail
0.012 breast carcinoma Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers D... BeFree 25781201 Detail
0.003 Carcinoma of lung NA BeFree Detail
<0.001 Malignant neoplasm of gastrointestinal tract NA BeFree Detail
<0.001 colon carcinoma NA BeFree Detail
0.001 stomach carcinoma NA BeFree Detail
<0.001 Central neuroblastoma NA BeFree Detail
0.120 congenital nystagmus NA CTD_human Detail
<0.001 Dissecting aneurysm of the thoracic aorta NA BeFree Detail
<0.001 Middle Cerebral Artery Occlusion Finally, we have also found that L-kynurenine, a tryptophan metabolite with AhR ... BeFree 25359166 Detail
<0.001 Malignant neoplasm of kidney NA BeFree Detail
<0.001 Ovarian failure NA BeFree Detail
<0.001 Sleep Disorders NA BeFree Detail
<0.001 Carcinogenicity NA BeFree Detail
0.120 Drug-Induced Liver Injury NA CTD_human Detail
<0.001 Sleeplessness NA BeFree Detail
<0.001 ovarian neoplasm NA BeFree Detail
<0.001 Vascular inflammations NA BeFree Detail
<0.001 Polyp of large intestine NA BeFree Detail
<0.001 Arthritis, Collagen-Induced NA BeFree Detail
0.120 Arthritis, Experimental NA CTD_human Detail
<0.001 Malignant neoplasm of ovary NA BeFree Detail
<0.001 Squamous cell carcinoma of the head and neck NA BeFree Detail
<0.001 sarcoma NA BeFree Detail
<0.001 Uroporphyrinuria NA BeFree Detail
0.002 Systemic arterial pressure NA GAD Detail
<0.001 Precursor B-cell lymphoblastic leukemia NA BeFree Detail
<0.001 Eosinophilic disorder NA BeFree Detail
<0.001 Hormone refractory prostate cancer NA BeFree Detail
<0.001 renal carcinoma NA BeFree Detail
0.003 Penis agenesis NA BeFree,GAD Detail
0.127 Mammary Neoplasms NA BeFree,CTD_human,LHGDN Detail
<0.001 Hepatocarcinogenesis NA BeFree Detail
<0.001 Mammary Tumorigenesis NA BeFree Detail
<0.001 Skin Carcinogenesis NA BeFree Detail
<0.001 Tumor Immunity These results suggest that AhR regulates the invasion of ccRCC and may be involv... BeFree 25523818 Detail
<0.001 Tumor Promotion NA BeFree Detail
<0.001 Xenograft Model NA BeFree Detail
0.005 colorectal cancer NA BeFree,GAD Detail
<0.001 Non-Malignant Ascites Adverse Event NA BeFree Detail
<0.001 Adenocarcinoma, Endometrioid NA BeFree Detail
<0.001 Disorder characterized by eosinophilia NA BeFree Detail
<0.001 Benign Prostatic Hyperplasia NA BeFree Detail
<0.001 VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding) NA BeFree Detail
<0.001 uterine corpus cancer Aryl hydrocarbon receptor exogenous ligand 3-methylchoranthrene inhibited endome... BeFree 24817304 Detail
<0.001 Precursor Cell Lymphoblastic Leukemia Lymphoma NA BeFree Detail
<0.001 Urothelial Carcinoma NA BeFree Detail
0.006 liver carcinoma We examined the expression kinetics of some of the aryl hydrocarbon receptor (Ah... BeFree 25637755 Detail
<0.001 Steatohepatitis NA BeFree Detail
0.120 Pancreatic cancer, adult NA CTD_human Detail
<0.001 Clear-cell metastatic renal cell carcinoma Therefore, inhibiting the activation of AhR may represent a potentially attracti... BeFree 25523818 Detail
<0.001 Triple Negative Breast Neoplasms NA BeFree Detail
<0.001 Melanocytic nevus of skin NA BeFree Detail
0.004 adenocarcinoma NA BeFree,LHGDN Detail
0.003 Alzheimer's disease NA BeFree,GAD Detail
<0.001 Angina, Unstable Compared with the controls, circulating AhR expression was found to be significa... BeFree 25620626 Detail
0.003 Anoxia NA LHGDN Detail
<0.001 arteriosclerosis NA BeFree Detail
<0.001 arthritis NA BeFree Detail
0.121 rheumatoid arthritis NA BeFree,CTD_human Detail
0.002 asthma We used a murine model for ovalbumin (OVA)-induced asthma to examine the effect ... BeFree 24819718 Detail
0.121 atherosclerosis NA BeFree,CTD_human Detail
0.001 Autoimmune Diseases NA BeFree Detail
0.002 azoospermia NA GAD Detail
0.120 Urinary Bladder Calculi (disorder) NA CTD_human Detail
0.007 Malignant neoplasm of urinary bladder NA BeFree,GAD Detail
0.120 Bone Resorption NA CTD_human Detail
<0.001 borderline personality disorder NA BeFree Detail
<0.001 Brain Neoplasms NA BeFree Detail
0.027 Malignant neoplasm of breast Depletion of the aryl hydrocarbon receptor in MDA-MB-231 human breast cancer cel... BeFree,GAD 24932473 Detail
0.027 Malignant neoplasm of breast DIM is an aryl hydrocarbon receptor (AhR) ligand and a potential anticancer agen... BeFree,GAD 25048790 Detail
0.027 Malignant neoplasm of breast A novel compound, NK150460, exhibits selective antitumor activity against breast... BeFree,GAD 25522763 Detail
0.027 Malignant neoplasm of breast Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers D... BeFree,GAD 25781201 Detail
<0.001 bronchopulmonary dysplasia NA BeFree Detail
<0.001 Malignant tumor of colon NA BeFree Detail
<0.001 Malignant neoplasm of endometrium Aryl hydrocarbon receptor exogenous ligand 3-methylchoranthrene inhibited endome... BeFree 24817304 Detail
<0.001 mucinous adenocarcinoma NA BeFree Detail
<0.001 Non-small cell lung carcinoma NA BeFree Detail
<0.001 renal cell carcinoma RCC cell lines were exposed to indirubin or 2,3,7,8-tetrachlorodibenzo-p-dioxin ... BeFree 25523818 Detail
Annotation

Annotations

DescrptionSourceLinks
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AHR-related compounds might be the new and promising therapeutic medicaments for the treatment of pa... DisGeNET Detail
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We examined the expression kinetics of some of the aryl hydrocarbon receptor (AhR)-regulated genes i... DisGeNET Detail
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Collectively, these data implicate polycyclic aromatic hydrocarbons and AhR in the regulation of p53... DisGeNET Detail
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Although AHR has been found differently expressed in pituitary adenomas, AHR gene mutation status ha... DisGeNET Detail
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L-kynurenine/aryl hydrocarbon receptor pathway mediates brain damage after experimental stroke. DisGeNET Detail
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It is particularly interesting that BCL6 - regulated by AhR/ARNT and wild-type MEF2B - may drive exp... DisGeNET Detail
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We assessed polymorphisms in the aryl hydrocarbon receptor (AhR-Arg554Lys), null variants of the glu... DisGeNET Detail
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In conclusion AhR knockdown alters the expression of genes known to enhance or inhibit cancer progre... DisGeNET Detail
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Collectively, our findings identify AhR as a regulator of multiple pathogenic pathways in experiment... DisGeNET Detail
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Activation of aryl hydrocarbon receptor promotes invasion of clear cell renal cell carcinoma and is ... DisGeNET Detail
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In this study, we evaluated patients with apparently sporadic GH-secreting pituitary adenoma for AHR... DisGeNET Detail
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Aryl hydrocarbon receptor exogenous ligand 3-methylchoranthrene inhibited endometrial cancer cells p... DisGeNET Detail
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Aryl hydrocarbon receptor (AHR) pathway has a key role in cellular detoxification mechanisms and see... DisGeNET Detail
Collectively, our results suggest that p53 affects AhR-dependent gene expression, PAH metabolism, an... DisGeNET Detail
The present study was designed to elucidate the role of the aryl hydrocarbon receptor (AhR), a major... DisGeNET Detail
NA DisGeNET Detail
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Depletion of the aryl hydrocarbon receptor in MDA-MB-231 human breast cancer cells altered the expre... DisGeNET Detail
DIM is an aryl hydrocarbon receptor (AhR) ligand and a potential anticancer agent, namely for the tr... DisGeNET Detail
A novel compound, NK150460, exhibits selective antitumor activity against breast cancer cell lines t... DisGeNET Detail
Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers DNA Damage in Human B... DisGeNET Detail
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Finally, we have also found that L-kynurenine, a tryptophan metabolite with AhR agonistic properties... DisGeNET Detail
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These results suggest that AhR regulates the invasion of ccRCC and may be involved in tumor immunity... DisGeNET Detail
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Aryl hydrocarbon receptor exogenous ligand 3-methylchoranthrene inhibited endometrial cancer cells p... DisGeNET Detail
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We examined the expression kinetics of some of the aryl hydrocarbon receptor (AhR)-regulated genes i... DisGeNET Detail
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Therefore, inhibiting the activation of AhR may represent a potentially attractive therapeutic targe... DisGeNET Detail
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Compared with the controls, circulating AhR expression was found to be significantly increased in pa... DisGeNET Detail
NA DisGeNET Detail
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We used a murine model for ovalbumin (OVA)-induced asthma to examine the effect of intranasal delive... DisGeNET Detail
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Depletion of the aryl hydrocarbon receptor in MDA-MB-231 human breast cancer cells altered the expre... DisGeNET Detail
DIM is an aryl hydrocarbon receptor (AhR) ligand and a potential anticancer agent, namely for the tr... DisGeNET Detail
A novel compound, NK150460, exhibits selective antitumor activity against breast cancer cell lines t... DisGeNET Detail
Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers DNA Damage in Human B... DisGeNET Detail
NA DisGeNET Detail
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Aryl hydrocarbon receptor exogenous ligand 3-methylchoranthrene inhibited endometrial cancer cells p... DisGeNET Detail
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RCC cell lines were exposed to indirubin or 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), AhR ligands,... DisGeNET Detail

Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
dbSNP
rs386493716 dbSNP
Genome
hg19
Position
chr7:17,171,814-17,385,774
Variant Type
snv
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