chr15:40987327:> Detail (hg19)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr15:40,987,327-41,024,538 |
| hg38 | chr15:40,695,129-40,732,340 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
| Score | Disease name | Description | Source | Pubmed | Links |
|---|---|---|---|---|---|
| 0.005 | squamous cell carcinoma | NA | BeFree,GAD | Detail | |
| <0.001 | Malignant tumor of cervix | NA | BeFree | Detail | |
| 0.002 | Chromosome Aberrations | NA | GAD | Detail | |
| <0.001 | Congenital chromosomal disease | NA | BeFree | Detail | |
| <0.001 | ulcerative colitis | The GC genotype frequency of RAD51 gene was significantly increased (p = 0.02) i... | BeFree | 25247297 | Detail |
| 0.001 | colorectal carcinoma | NA | BeFree | Detail | |
| 0.002 | Colorectal Neoplasms | NA | GAD | Detail | |
| <0.001 | cystic fibrosis | NA | BeFree | Detail | |
| 0.002 | Deglutition Disorders | NA | GAD | Detail | |
| <0.001 | diphtheria | NA | BeFree | Detail | |
| 0.002 | DNA Damage | NA | GAD | Detail | |
| <0.001 | Esophageal Neoplasms | NA | BeFree | Detail | |
| 0.004 | Fanconi anemia | Here, we report a de novo heterozygous T131P mutation in RAD51/FANCR, the key re... | BeFree | 26253028 | Detail |
| <0.001 | fibrosarcoma | NA | BeFree | Detail | |
| <0.001 | glioblastoma | In addition, HDACi reduce the expression of proteins involved in DNA repair (Rad... | BeFree | 25275596 | Detail |
| 0.006 | Glioma | In addition, HDACi reduce the expression of proteins involved in DNA repair (Rad... | BeFree,GAD | 25275596 | Detail |
| 0.120 | IgA glomerulonephritis | NA | CTD_human | Detail | |
| 0.127 | Head and Neck Neoplasms | NA | CTD_human,GAD,LHGDN | Detail | |
| <0.001 | Herpes Simplex Infections | NA | BeFree | Detail | |
| <0.001 | HIV Infections | NA | BeFree | Detail | |
| 0.080 | Hypertensive disease | NA | RGD | Detail | |
| <0.001 | Fibroid Tumor | NA | BeFree | Detail | |
| 0.008 | leukemia | The pooled results showed that the leukemia risk was not significantly associate... | BeFree,GAD,LHGDN | 23978154 | Detail |
| 0.003 | chronic lymphocytic leukemia | NA | BeFree,GAD | Detail | |
| <0.001 | Leukemia, Lymphocytic, Acute, L1 | We also observed significant influence of hOGG-RAD51 and NBN-RAD51 interactions ... | BeFree | 25746326 | Detail |
| 0.010 | Leukemia, Myelocytic, Acute | Genetic polymorphisms of RAD51 and XRCC3 and acute myeloid leukemia risk: a meta... | BeFree,GAD | 23978154 | Detail |
| 0.005 | myeloid leukemia | NA | GAD | Detail | |
| <0.001 | Myeloid Leukemia, Chronic | NA | BeFree | Detail | |
| 0.080 | Liver Neoplasms, Experimental | NA | RGD | Detail | |
| 0.002 | Chronic Obstructive Airway Disease | NA | GAD | Detail | |
| 0.003 | Lung Neoplasms | NA | LHGDN | Detail | |
| <0.001 | Lyme disease | NA | BeFree | Detail | |
| <0.001 | lymphoma | NA | BeFree | Detail | |
| 0.002 | Lymphoma, Non-Hodgkin | NA | GAD | Detail | |
| 0.003 | Malignant neoplasm of stomach | RAD51 potentiates synergistic effects of chemotherapy with PCI-24781 and cis-dia... | BeFree,GAD | 25110436 | Detail |
| <0.001 | medulloblastoma | NA | BeFree | Detail | |
| 0.002 | Meningeal Neoplasms | NA | GAD | Detail | |
| 0.002 | meningioma | NA | GAD | Detail | |
| <0.001 | Mouth Neoplasms | NA | BeFree | Detail | |
| <0.001 | Movement Disorders | Selective chromatid segregation mechanism invoked for the human congenital mirro... | BeFree | 25210500 | Detail |
| <0.001 | multiple myeloma | NA | BeFree | Detail | |
| 0.002 | multiple sclerosis | NA | GAD | Detail | |
| 0.001 | Neoplasm Metastasis | NA | BeFree | Detail | |
| 0.002 | acoustic neuroma | NA | GAD | Detail | |
| <0.001 | osteosarcoma | NA | BeFree | Detail | |
| 0.006 | ovarian carcinoma | The RAD51 paralog RAD51C has been identified as a breast and ovarian cancer susc... | BeFree | 25292178 | Detail |
| 0.006 | ovarian carcinoma | Augmentation of response to chemotherapy by microRNA-506 through regulation of R... | BeFree | 25995442 | Detail |
| 0.006 | ovarian carcinoma | We identified 13 RAD51 mutations (0.65%) in unaffected UK_FOCSS participants (RA... | BeFree | 26261251 | Detail |
| 0.080 | Pancreatic Neoplasm | NA | RGD | Detail | |
| <0.001 | Parathyroid Neoplasms | NA | BeFree | Detail | |
| <0.001 | pneumonia | NA | BeFree | Detail | |
| 0.002 | Precancerous Conditions | NA | GAD | Detail | |
| <0.001 | Preleukemia | NA | BeFree | Detail | |
| <0.001 | Prostatic Neoplasms | NA | BeFree | Detail | |
| 0.002 | Radiodermatitis | NA | GAD | Detail | |
| <0.001 | Seizures | Using in vitro OHC we found decreased NG2 vascular staining and increased PDGFRβ... | BeFree | 25088711 | Detail |
| 0.005 | Thyroid Neoplasm | NA | GAD | Detail | |
| <0.001 | Uterine Fibroids | NA | BeFree | Detail | |
| <0.001 | Werner syndrome | NA | BeFree | Detail | |
| <0.001 | acute leukemia | NA | BeFree | Detail | |
| <0.001 | esophageal carcinoma | NA | BeFree | Detail | |
| 0.002 | Malignant neoplasm of brain | NA | GAD | Detail | |
| <0.001 | Tumor Progression | NA | BeFree | Detail | |
| <0.001 | uveal melanoma | NA | BeFree | Detail | |
| <0.001 | Metastatic malignant neoplasm to brain | NA | BeFree | Detail | |
| <0.001 | Hyperparathyroidism, Primary | NA | BeFree | Detail | |
| <0.001 | pancreatic carcinoma | NA | BeFree | Detail | |
| <0.001 | Gastrointestinal Stromal Tumors | NA | BeFree | Detail | |
| 0.001 | Sporadic Breast Carcinoma | Our results suggest XRCC1 Arg399Gln and XRCC3 Thr241Met DNA repair polymorphisms... | BeFree | 17063276 | Detail |
| 0.123 | Breast Cancer, Familial | Our results suggest XRCC1 Arg399Gln and XRCC3 Thr241Met DNA repair polymorphisms... | BeFree | 17063276 | Detail |
| 0.010 | Malignant neoplasm of lung | Our results show that depletion of endogenous Rad51 is sufficient to inhibit the... | BeFree,GAD | 25640347 | Detail |
| <0.001 | parathyroid adenoma | NA | BeFree | Detail | |
| <0.001 | Mirror hands | Selective chromatid segregation mechanism invoked for the human congenital mirro... | BeFree | 25210500 | Detail |
| <0.001 | bilateral breast cancer | NA | BeFree | Detail | |
| <0.001 | Adenocarcinoma of pancreas | NA | BeFree | Detail | |
| <0.001 | cervix carcinoma | NA | BeFree | Detail | |
| <0.001 | Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse | NA | BeFree | Detail | |
| <0.001 | Ovarian dysgenesis | Our findings help delineate the intricate manner in which Hop2-Mnd1 engages and ... | BeFree | 25820426 | Detail |
| <0.001 | intrahepatic cholangiocarcinoma | NA | BeFree | Detail | |
| 0.123 | Breast Cancer, Familial | Germline mutations in BRCA and RAD51 genes, involved in DSB repair, are strongly... | BeFree,CLINVAR | 25409685 | Detail |
| <0.001 | Multiple malignancy | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of pancreas | NA | BeFree | Detail | |
| <0.001 | Secondary malignant neoplasm of pancreas | NA | BeFree | Detail | |
| 0.004 | Malignant neoplasm of prostate | Silencing RAD51 sensitized prostate cancer cells to SAHA and olaparib alone. | BeFree,GAD | 25127709 | Detail |
| 0.001 | Mirror movements disorder | Congenital mirror movements: phenotypes associated with DCC and RAD51 mutations. | BeFree | 25813273 | Detail |
| <0.001 | endometrial carcinoma | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of esophagus | NA | BeFree | Detail | |
| <0.001 | Thyroid carcinoma | NA | BeFree | Detail | |
| <0.001 | Osteosarcoma of bone | NA | BeFree | Detail | |
| 0.004 | Carcinogenesis | This study reveals an elaborate but highly organized molecular interplay between... | BeFree | 24835992 | Detail |
| <0.001 | Chemical Carcinogenesis | Homologous recombination repair signaling in chemical carcinogenesis: prolonged ... | BeFree | 25173789 | Detail |
| 0.001 | prostate carcinoma | Silencing RAD51 sensitized prostate cancer cells to SAHA and olaparib alone. | BeFree | 25127709 | Detail |
| 0.120 | Hereditary Breast and Ovarian Cancer Syndrome | NA | ORPHANET | Detail | |
| 0.003 | Epithelial ovarian cancer | NA | BeFree,GAD | Detail | |
| 0.019 | breast carcinoma | Here, we show that the breast cancer susceptibility protein BRCA2, a key Rad51 b... | BeFree | 24835992 | Detail |
| 0.019 | breast carcinoma | Due to the severity of phenotype and the integrity of exon 11 encoding RAD51 bin... | BeFree | 25304112 | Detail |
| 0.019 | breast carcinoma | The RAD51 135G>C polymorphism is related to the effect of adjuvant therapy in ea... | BeFree | 25354554 | Detail |
| 0.019 | breast carcinoma | Correlation between selected XRCC2, XRCC3 and RAD51 gene polymorphisms and prima... | BeFree | 25556451 | Detail |
| 0.019 | breast carcinoma | Evaluation of miRNA-binding-site SNPs of MRE11A, NBS1, RAD51 and RAD52 involved ... | BeFree | 25566853 | Detail |
| 0.019 | breast carcinoma | Many known breast cancer specific mutated genes like RAD51, BRIP1, ER, PGR and P... | BeFree | 25570853 | Detail |
| 0.019 | breast carcinoma | DNA double-strand break (DSB) repair is assisted by PARP1 expression in BRCA-mut... | BeFree | 25690937 | Detail |
| 0.002 | Carcinoma of lung | Our results show that depletion of endogenous Rad51 is sufficient to inhibit the... | BeFree | 25640347 | Detail |
| <0.001 | Secondary malignant neoplasm of lymph node | NA | BeFree | Detail | |
| <0.001 | colon carcinoma | The hypothesis could be tested by in vitro inhibition of Rad51 protein, orthotop... | BeFree | 25253953 | Detail |
| <0.001 | stomach carcinoma | RAD51 potentiates synergistic effects of chemotherapy with PCI-24781 and cis-dia... | BeFree | 25110436 | Detail |
| <0.001 | Small Lymphocytic Lymphoma | NA | BeFree | Detail | |
| 0.080 | Cardiomyopathies | NA | BeFree,RGD | Detail | |
| 0.002 | Haematotoxicity | NA | GAD | Detail | |
| <0.001 | Invasive Ductal Breast Carcinoma | NA | BeFree | Detail | |
| 0.018 | Malignant neoplasm of ovary | The RAD51 paralog RAD51C has been identified as a breast and ovarian cancer susc... | BeFree,GAD | 25292178 | Detail |
| 0.018 | Malignant neoplasm of ovary | Augmentation of response to chemotherapy by microRNA-506 through regulation of R... | BeFree,GAD | 25995442 | Detail |
| 0.018 | Malignant neoplasm of ovary | We identified 13 RAD51 mutations (0.65%) in unaffected UK_FOCSS participants (RA... | BeFree,GAD | 26261251 | Detail |
| 0.002 | Squamous cell carcinoma of the head and neck | NA | BeFree | Detail | |
| 0.003 | sarcoma | NA | BeFree,LHGDN | Detail | |
| <0.001 | Hereditary Malignant Neoplasm | NA | BeFree | Detail | |
| 0.001 | Sporadic Breast Carcinoma | NA | BeFree | Detail | |
| <0.001 | Treatment related acute myeloid leukaemia | NA | BeFree | Detail | |
| 0.151 | Mammary Neoplasms | We determined their HR capacity by studying the formation of ionizing radiation ... | BeFree,CTD_human,GAD,LHGDN | 24963051 | Detail |
| 0.151 | Mammary Neoplasms | Here we describe a set of mutations associated with human breast tumors that occ... | BeFree,CTD_human,GAD,LHGDN | 25539919 | Detail |
| 0.003 | colorectal cancer | NA | BeFree,GAD | Detail | |
| <0.001 | Glioblastoma multiforme | In addition, HDACi reduce the expression of proteins involved in DNA repair (Rad... | BeFree | 25275596 | Detail |
| 0.001 | prostate carcinoma | We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in ... | BeFree | 19914098 | Detail |
| <0.001 | uterine corpus cancer | NA | BeFree | Detail | |
| <0.001 | liver carcinoma | NA | BeFree | Detail | |
| <0.001 | Nasopharyngeal carcinoma | Inhibition of autophagy enhances the radiosensitivity of nasopharyngeal carcinom... | BeFree | 25175062 | Detail |
| 0.004 | Malignant neoplasm of prostate | We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in ... | BeFree | 19914098 | Detail |
| 0.005 | myelodysplastic syndrome | NA | BeFree,GAD | Detail | |
| 0.003 | FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) | Here, we report a de novo heterozygous T131P mutation in RAD51/FANCR, the key re... | BeFree | 26253028 | Detail |
| 0.001 | Triple Negative Breast Neoplasms | NA | BeFree | Detail | |
| <0.001 | Pneumonitis | NA | BeFree | Detail | |
| 0.005 | adenocarcinoma | NA | GAD,LHGDN | Detail | |
| <0.001 | adenoma | NA | BeFree | Detail | |
| <0.001 | anemia | NA | BeFree | Detail | |
| 0.080 | Anoxia | NA | RGD | Detail | |
| 0.007 | Malignant neoplasm of urinary bladder | NA | BeFree,GAD | Detail | |
| 0.005 | Brain Neoplasms | NA | BeFree,GAD | Detail | |
| 0.216 | Malignant neoplasm of breast | Here, we show that the breast cancer susceptibility protein BRCA2, a key Rad51 b... | BeFree,GAD,UNIPROT | 24835992 | Detail |
| 0.216 | Malignant neoplasm of breast | Due to the severity of phenotype and the integrity of exon 11 encoding RAD51 bin... | BeFree,GAD,UNIPROT | 25304112 | Detail |
| 0.216 | Malignant neoplasm of breast | The RAD51 135G>C polymorphism is related to the effect of adjuvant therapy in ea... | BeFree,GAD,UNIPROT | 25354554 | Detail |
| 0.216 | Malignant neoplasm of breast | Correlation between selected XRCC2, XRCC3 and RAD51 gene polymorphisms and prima... | BeFree,GAD,UNIPROT | 25556451 | Detail |
| 0.216 | Malignant neoplasm of breast | Evaluation of miRNA-binding-site SNPs of MRE11A, NBS1, RAD51 and RAD52 involved ... | BeFree,GAD,UNIPROT | 25566853 | Detail |
| 0.216 | Malignant neoplasm of breast | Many known breast cancer specific mutated genes like RAD51, BRIP1, ER, PGR and P... | BeFree,GAD,UNIPROT | 25570853 | Detail |
| 0.216 | Malignant neoplasm of breast | DNA double-strand break (DSB) repair is assisted by PARP1 expression in BRCA-mut... | BeFree,GAD,UNIPROT | 25690937 | Detail |
| <0.001 | Malignant tumor of colon | The hypothesis could be tested by in vitro inhibition of Rad51 protein, orthotop... | BeFree | 25253953 | Detail |
| <0.001 | Malignant neoplasm of endometrium | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of thyroid | NA | BeFree | Detail | |
| 0.004 | Non-small cell lung carcinoma | We conclude that independent Rad51 expression is critical to the survival of A54... | BeFree | 25640347 | Detail |
| 0.004 | Non-small cell lung carcinoma | Minocycline enhances mitomycin C-induced cytotoxicity through down-regulating ER... | BeFree | 26212550 | Detail |
| 0.002 | Carcinoma, Papillary | NA | GAD | Detail |
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The GC genotype frequency of RAD51 gene was significantly increased (p = 0.02) in the UC group (50.3... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Here, we report a de novo heterozygous T131P mutation in RAD51/FANCR, the key recombinase essential ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In addition, HDACi reduce the expression of proteins involved in DNA repair (Rad51), mitotic spindle... | DisGeNET | Detail |
| In addition, HDACi reduce the expression of proteins involved in DNA repair (Rad51), mitotic spindle... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The pooled results showed that the leukemia risk was not significantly associated with RAD51: the sa... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| We also observed significant influence of hOGG-RAD51 and NBN-RAD51 interactions on susceptibility to... | DisGeNET | Detail |
| Genetic polymorphisms of RAD51 and XRCC3 and acute myeloid leukemia risk: a meta-analysis. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| RAD51 potentiates synergistic effects of chemotherapy with PCI-24781 and cis-diamminedichloroplatinu... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Selective chromatid segregation mechanism invoked for the human congenital mirror hand movement diso... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The RAD51 paralog RAD51C has been identified as a breast and ovarian cancer susceptibility gene. | DisGeNET | Detail |
| Augmentation of response to chemotherapy by microRNA-506 through regulation of RAD51 in serous ovari... | DisGeNET | Detail |
| We identified 13 RAD51 mutations (0.65%) in unaffected UK_FOCSS participants (RAD51C, n = 7; RAD51D,... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Using in vitro OHC we found decreased NG2 vascular staining and increased PDGFRβ(+) ramifications as... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Our results suggest XRCC1 Arg399Gln and XRCC3 Thr241Met DNA repair polymorphisms as important biomar... | DisGeNET | Detail |
| Our results suggest XRCC1 Arg399Gln and XRCC3 Thr241Met DNA repair polymorphisms as important biomar... | DisGeNET | Detail |
| Our results show that depletion of endogenous Rad51 is sufficient to inhibit the growth of the A549 ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Selective chromatid segregation mechanism invoked for the human congenital mirror hand movement diso... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Our findings help delineate the intricate manner in which Hop2-Mnd1 engages and functions with RAD51... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Germline mutations in BRCA and RAD51 genes, involved in DSB repair, are strongly associated with her... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Silencing RAD51 sensitized prostate cancer cells to SAHA and olaparib alone. | DisGeNET | Detail |
| Congenital mirror movements: phenotypes associated with DCC and RAD51 mutations. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| This study reveals an elaborate but highly organized molecular interplay between Rad51 regulators an... | DisGeNET | Detail |
| Homologous recombination repair signaling in chemical carcinogenesis: prolonged particulate hexavale... | DisGeNET | Detail |
| Silencing RAD51 sensitized prostate cancer cells to SAHA and olaparib alone. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Here, we show that the breast cancer susceptibility protein BRCA2, a key Rad51 binding partner, coor... | DisGeNET | Detail |
| Due to the severity of phenotype and the integrity of exon 11 encoding RAD51 binding domain, and the... | DisGeNET | Detail |
| The RAD51 135G>C polymorphism is related to the effect of adjuvant therapy in early breast cancer. | DisGeNET | Detail |
| Correlation between selected XRCC2, XRCC3 and RAD51 gene polymorphisms and primary breast cancer in ... | DisGeNET | Detail |
| Evaluation of miRNA-binding-site SNPs of MRE11A, NBS1, RAD51 and RAD52 involved in HRR pathway genes... | DisGeNET | Detail |
| Many known breast cancer specific mutated genes like RAD51, BRIP1, ER, PGR and PTPRD have been succe... | DisGeNET | Detail |
| DNA double-strand break (DSB) repair is assisted by PARP1 expression in BRCA-mutated tumours, wherea... | DisGeNET | Detail |
| Our results show that depletion of endogenous Rad51 is sufficient to inhibit the growth of the A549 ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The hypothesis could be tested by in vitro inhibition of Rad51 protein, orthotopic grafting of human... | DisGeNET | Detail |
| RAD51 potentiates synergistic effects of chemotherapy with PCI-24781 and cis-diamminedichloroplatinu... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The RAD51 paralog RAD51C has been identified as a breast and ovarian cancer susceptibility gene. | DisGeNET | Detail |
| Augmentation of response to chemotherapy by microRNA-506 through regulation of RAD51 in serous ovari... | DisGeNET | Detail |
| We identified 13 RAD51 mutations (0.65%) in unaffected UK_FOCSS participants (RAD51C, n = 7; RAD51D,... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| We determined their HR capacity by studying the formation of ionizing radiation induced foci (IRIF) ... | DisGeNET | Detail |
| Here we describe a set of mutations associated with human breast tumors that occur in a common struc... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| In addition, HDACi reduce the expression of proteins involved in DNA repair (Rad51), mitotic spindle... | DisGeNET | Detail |
| We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in 5 genes involved in ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Inhibition of autophagy enhances the radiosensitivity of nasopharyngeal carcinoma by reducing Rad51 ... | DisGeNET | Detail |
| We examined the association between PC risk with nonsynonymous SNPs (nsSNPs) in 5 genes involved in ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Here, we report a de novo heterozygous T131P mutation in RAD51/FANCR, the key recombinase essential ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Here, we show that the breast cancer susceptibility protein BRCA2, a key Rad51 binding partner, coor... | DisGeNET | Detail |
| Due to the severity of phenotype and the integrity of exon 11 encoding RAD51 binding domain, and the... | DisGeNET | Detail |
| The RAD51 135G>C polymorphism is related to the effect of adjuvant therapy in early breast cancer. | DisGeNET | Detail |
| Correlation between selected XRCC2, XRCC3 and RAD51 gene polymorphisms and primary breast cancer in ... | DisGeNET | Detail |
| Evaluation of miRNA-binding-site SNPs of MRE11A, NBS1, RAD51 and RAD52 involved in HRR pathway genes... | DisGeNET | Detail |
| Many known breast cancer specific mutated genes like RAD51, BRIP1, ER, PGR and PTPRD have been succe... | DisGeNET | Detail |
| DNA double-strand break (DSB) repair is assisted by PARP1 expression in BRCA-mutated tumours, wherea... | DisGeNET | Detail |
| The hypothesis could be tested by in vitro inhibition of Rad51 protein, orthotopic grafting of human... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| We conclude that independent Rad51 expression is critical to the survival of A549 cells and can be a... | DisGeNET | Detail |
| Minocycline enhances mitomycin C-induced cytotoxicity through down-regulating ERK1/2-mediated Rad51 ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- dbSNP
- rs386493716 dbSNP
- Genome
- hg19
- Position
- chr15:40,987,327-41,024,538
- Variant Type
- snv
Genome browser