Annotation Detail
Information
- Associated Genes
- RAD51
- Associated Variants
-
RAD51 MUTATION
RAD51 MUTATION - Associated Disease
- Malignant neoplasm of breast
- Source Database
- DisGeNET
- Description
- DNA double-strand break (DSB) repair is assisted by PARP1 expression in BRCA-mutated tumours, whereas the loss of DSB repair via RAD51 is predominant in BRCA1 rather than BRCA2 BC.
- Pubmed
- 25690937
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 11
- Original source reporting the Gene Disease association
- BeFree,GAD,UNIPROT
- DisGENET score for the Gene Disease association
- 0.215831721849207
Drugs