Annotation Detail
Information
- Associated Genes
- RAD51
- Associated Variants
-
RAD51 MUTATION
RAD51 MUTATION - Associated Disease
- breast carcinoma
- Source Database
- DisGeNET
- Description
- Here, we show that the breast cancer susceptibility protein BRCA2, a key Rad51 binding partner, coordinates the activity of the central cell-cycle drivers CDKs and Plk1 to promote Rad51-mediated genome stability control.
- Pubmed
- 24835992
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 3
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0190009310456212
Drugs