chr12:66218240:> Detail (hg19)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr12:66,218,240-66,360,071 |
| hg38 | chr12:65,824,460-65,966,291 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
| Score | Disease name | Description | Source | Pubmed | Links |
|---|---|---|---|---|---|
| <0.001 | squamous cell carcinoma | HMGA2 is down-regulated by microRNA let-7 and associated with epithelial-mesench... | BeFree | 24612219 | Detail |
| <0.001 | squamous cell carcinoma | The RT-PCR and immunohistochemistry analyses showed that HMGA2 was expressed in ... | BeFree | 25823555 | Detail |
| <0.001 | carcinosarcoma | NA | BeFree | Detail | |
| 0.002 | Cardiovascular Diseases | NA | GAD | Detail | |
| 0.004 | Congenital chromosomal disease | NA | BeFree | Detail | |
| <0.001 | colorectal carcinoma | NA | BeFree | Detail | |
| <0.001 | Phyllodes Tumor | NA | BeFree | Detail | |
| 0.121 | Diabetes Mellitus, Non-Insulin-Dependent | NA | BeFree,GWASCAT | Detail | |
| <0.001 | Diabetic Nephropathy | NA | BeFree | Detail | |
| 0.001 | Dwarfism | NA | BeFree | Detail | |
| <0.001 | endometriosis | NA | BeFree | Detail | |
| <0.001 | Exanthema | Beyond recalculating frequencies for the previously reported frequent integratio... | BeFree | 25581428 | Detail |
| <0.001 | Failure to Thrive | NA | BeFree | Detail | |
| <0.001 | Gigantism | NA | BeFree | Detail | |
| 0.001 | glioblastoma | NA | BeFree | Detail | |
| 0.003 | Glioma | NA | BeFree,GAD | Detail | |
| 0.009 | Hamartoma | NA | BeFree,LHGDN | Detail | |
| <0.001 | HIV Infections | NA | BeFree | Detail | |
| 0.002 | Insulin resistance | NA | GAD | Detail | |
| <0.001 | Kidney Diseases | NA | BeFree | Detail | |
| 0.015 | Fibroid Tumor | These findings strongly suggest that MED12 mutations and HMGA2 overexpression ar... | BeFree,GAD,LHGDN | 24390224 | Detail |
| 0.015 | Fibroid Tumor | All leiomyomas with HMGA2 overexpression also revealed an activation of PLAG1 in... | BeFree,GAD,LHGDN | 24516594 | Detail |
| 0.015 | Fibroid Tumor | Whereas 70.0% (14/20) HMGA2-mutated fibroids made their appearance as solitary n... | BeFree,GAD,LHGDN | 25272295 | Detail |
| 0.015 | Fibroid Tumor | Overexpression of the truncated form of High Mobility Group A proteins (HMGA2) i... | BeFree,GAD,LHGDN | 25542836 | Detail |
| <0.001 | leiomyosarcoma | MED12 and HMGA2 mutations: two independent genetic events in uterine leiomyoma a... | BeFree | 24390224 | Detail |
| <0.001 | leukemia | These findings show that HMGA2-driven leukemia in mice closely resembles spontan... | BeFree | 25014774 | Detail |
| <0.001 | chronic lymphocytic leukemia | NA | BeFree | Detail | |
| <0.001 | Acute lymphocytic leukemia | NA | BeFree | Detail | |
| 0.003 | Myeloid Leukemia, Chronic | NA | BeFree,LHGDN | Detail | |
| 0.015 | lipoma | Further cytogenetic studies of pediatric lipoma would be useful to determinate w... | BeFree | 26319758 | Detail |
| <0.001 | lipomatosis | NA | BeFree | Detail | |
| 0.008 | liposarcoma | NA | BeFree,LHGDN | Detail | |
| 0.008 | Lung Neoplasms | NA | LHGDN | Detail | |
| <0.001 | lymphoma | NA | BeFree | Detail | |
| 0.002 | Malignant neoplasm of stomach | Coexpression of HMGA2 and Oct4 predicts an unfavorable prognosis in human gastri... | BeFree | 25037576 | Detail |
| 0.002 | Malignant neoplasm of stomach | RKIP inhibits gastric cancer cell survival and invasion by regulating the expres... | BeFree | 25172097 | Detail |
| 0.001 | paroxysmal nocturnal hemoglobinuria | NA | BeFree | Detail | |
| <0.001 | Meigs Syndrome | NA | BeFree | Detail | |
| <0.001 | melanoma | The RT-PCR and immunohistochemistry analyses showed that HMGA2 was expressed in ... | BeFree | 25823555 | Detail |
| 0.009 | Mixed Salivary Gland Tumor | NA | BeFree,LHGDN | Detail | |
| <0.001 | Myelodysplasia | NA | BeFree | Detail | |
| 0.001 | myelofibrosis | Overexpression of high mobility group AT-hook 2 (Hmga2), which is negatively reg... | BeFree | 25236537 | Detail |
| <0.001 | Myeloproliferative disease | Dysregulation of the MIRLET7/HMGA2 axis with methylation of the CDKN2A promoter ... | BeFree | 25236537 | Detail |
| <0.001 | myoepithelioma | NA | BeFree | Detail | |
| <0.001 | myoma | NA | BeFree | Detail | |
| <0.001 | Myxoma | NA | BeFree | Detail | |
| 0.005 | Neoplasm Metastasis | The aim of this study was to analyze the association between HMGA2 and Oct4 expr... | BeFree | 25037576 | Detail |
| 0.005 | Neoplasm Metastasis | Finally, we demonstrate that the expression pattern of FHIT and miR-30c is inver... | BeFree | 25340791 | Detail |
| 0.005 | Neoplasm Metastasis | Here, we found that low miR-145 expression and HMGA2 overexpression determined b... | BeFree | 25444913 | Detail |
| 0.005 | Neoplasm Metastasis | HMGA2 was upregulated in NPC cell lines and clinical specimens (P < 0.01), and H... | BeFree | 26025649 | Detail |
| <0.001 | neuroblastoma | NA | BeFree | Detail | |
| <0.001 | obesity | NA | BeFree | Detail | |
| <0.001 | Degenerative polyarthritis | NA | BeFree | Detail | |
| <0.001 | osteosarcoma | MicroRNA-490-3p regulates cell proliferation and apoptosis by targeting HMGA2 in... | BeFree | 26341146 | Detail |
| 0.003 | ovarian carcinoma | Low miR-145 and high HMGA2 expressions are potential biomarkers of poor prognosi... | BeFree | 25444913 | Detail |
| 0.003 | Pancreatic Neoplasm | NA | LHGDN | Detail | |
| 0.002 | pituitary adenoma | NA | BeFree | Detail | |
| 0.001 | Pituitary Diseases | NA | BeFree | Detail | |
| 0.006 | Pituitary Neoplasms | NA | BeFree,LHGDN | Detail | |
| 0.120 | polycystic ovary syndrome | NA | GWASCAT | Detail | |
| 0.003 | polycythemia vera | HMGA2 mRNA expression, especially variant 1 with 3'UTR that contains MIRLET7-spe... | BeFree,LHGDN | 25236537 | Detail |
| <0.001 | Preleukemia | NA | BeFree | Detail | |
| 0.001 | prolactinoma | NA | BeFree | Detail | |
| <0.001 | retinoblastoma | NA | BeFree | Detail | |
| <0.001 | rhabdomyosarcoma | NA | BeFree | Detail | |
| <0.001 | Soft Tissue Neoplasms | NA | BeFree | Detail | |
| 0.003 | Stomach Neoplasms | NA | LHGDN | Detail | |
| <0.001 | synovial sarcoma | NA | BeFree | Detail | |
| <0.001 | teratoma | NA | BeFree | Detail | |
| <0.001 | Testicular Neoplasms | NA | BeFree | Detail | |
| <0.001 | tetanus | NA | BeFree | Detail | |
| <0.001 | Thrombocythemia, Essential | HMGA2 mRNA expression, especially variant 1 with 3'UTR that contains MIRLET7-spe... | BeFree | 25236537 | Detail |
| 0.001 | Thyroid Neoplasm | Correlated expression of HMGA2 and PLAG1 in thyroid tumors, uterine leiomyomas a... | BeFree | 24516594 | Detail |
| <0.001 | Thyroid Nodule | NA | BeFree | Detail | |
| 0.002 | Tooth eruption | NA | GAD | Detail | |
| <0.001 | Trisomy | NA | BeFree | Detail | |
| 0.013 | Uterine Fibroids | MED12 and HMGA2 mutations: two independent genetic events in uterine leiomyoma a... | BeFree | 24390224 | Detail |
| 0.013 | Uterine Fibroids | All leiomyomas with HMGA2 overexpression also revealed an activation of PLAG1 in... | BeFree | 24516594 | Detail |
| 0.013 | Uterine Fibroids | Whereas 70.0% (14/20) HMGA2-mutated fibroids made their appearance as solitary n... | BeFree | 25272295 | Detail |
| 0.013 | Uterine Fibroids | Overexpression of the truncated form of High Mobility Group A proteins (HMGA2) i... | BeFree | 25542836 | Detail |
| 0.002 | Uterine Neoplasms | NA | GAD | Detail | |
| 0.004 | benign neoplasm | NA | BeFree | Detail | |
| <0.001 | Hamartoma of lung | NA | BeFree | Detail | |
| <0.001 | Oral Cavity Carcinoma | The high mobility group A2 (HMGA2) protein was found to be highly expressed in h... | BeFree | 25245141 | Detail |
| <0.001 | Malignant neoplasm of nasopharynx | Downregulating HMGA2 attenuates epithelial-mesenchymal transition-induced invasi... | BeFree | 26025649 | Detail |
| <0.001 | Malignant neoplasm of gallbladder | NA | BeFree | Detail | |
| 0.001 | Uterine Polyp | NA | BeFree | Detail | |
| <0.001 | Russell-Silver syndrome | NA | BeFree | Detail | |
| <0.001 | Tumor Progression | NA | BeFree | Detail | |
| <0.001 | Adenocarcinoma, Oxyphilic | NA | BeFree | Detail | |
| <0.001 | follicular adenoma | NA | BeFree | Detail | |
| <0.001 | Undifferentiated carcinoma | NA | BeFree | Detail | |
| 0.121 | Liposarcoma, Dedifferentiated | NA | BeFree,ORPHANET | Detail | |
| <0.001 | Liposarcoma, Myxoid | NA | BeFree | Detail | |
| <0.001 | Fibroadenoma | NA | BeFree | Detail | |
| 0.004 | smooth muscle tumor | NA | BeFree,LHGDN | Detail | |
| <0.001 | embryonal carcinoma | NA | BeFree | Detail | |
| <0.001 | Follicular thyroid carcinoma | NA | BeFree | Detail | |
| <0.001 | mucoepidermoid carcinoma | NA | BeFree | Detail | |
| <0.001 | Rhabdoid Tumor | NA | BeFree | Detail | |
| <0.001 | Neuroendocrine Tumors | NA | BeFree | Detail | |
| <0.001 | childhood rhabdomyosarcoma | NA | BeFree | Detail | |
| <0.001 | Lip and oral cavity carcinoma | The high mobility group A2 (HMGA2) protein was found to be highly expressed in h... | BeFree | 25245141 | Detail |
| <0.001 | gallbladder carcinoma | NA | BeFree | Detail | |
| 0.001 | pancreatic carcinoma | Further validation showed that overexpression of PSCA was significantly associat... | BeFree | 25502777 | Detail |
| <0.001 | Cancer of Nasopharynx | Downregulating HMGA2 attenuates epithelial-mesenchymal transition-induced invasi... | BeFree | 26025649 | Detail |
| <0.001 | PULMONARY LYMPHANGIOMYOMATOSIS | NA | BeFree | Detail | |
| 0.001 | Malignant neoplasm of lung | Finally, we demonstrate that the expression pattern of FHIT and miR-30c is inver... | BeFree | 25340791 | Detail |
| 0.002 | Ventricular Dysfunction, Left | NA | GAD | Detail | |
| <0.001 | Endometrioma | NA | BeFree | Detail | |
| <0.001 | Carcinoma breast stage IV | NA | BeFree | Detail | |
| 0.002 | Solid tumour | NA | BeFree | Detail | |
| <0.001 | Leiomyosarcoma of uterus | NA | BeFree | Detail | |
| <0.001 | diffuse astrocytoma | NA | BeFree | Detail | |
| <0.001 | Papillary serous cystadenocarcinoma | NA | BeFree | Detail | |
| <0.001 | Benign Mesenchymoma | NA | BeFree | Detail | |
| <0.001 | anaplastic astrocytoma | NA | BeFree | Detail | |
| <0.001 | Thyroid associated opthalmopathies | NA | BeFree | Detail | |
| 0.001 | Carcinoma ex pleomorphic adenoma | NA | BeFree | Detail | |
| <0.001 | Pleomorphic adenoma of lacrimal gland | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of pancreas | Further validation showed that overexpression of PSCA was significantly associat... | BeFree | 25502777 | Detail |
| <0.001 | Pleomorphic adenoma of parotid gland | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of prostate | NA | BeFree | Detail | |
| 0.120 | Birth length | NA | GWASCAT | Detail | |
| 0.120 | Infant length | NA | GWASCAT | Detail | |
| <0.001 | Follicular neoplasm | NA | BeFree | Detail | |
| <0.001 | Overweight | NA | BeFree | Detail | |
| <0.001 | Thyroid carcinoma | NA | BeFree | Detail | |
| <0.001 | Malignant glioma | NA | BeFree | Detail | |
| <0.001 | Osteosarcoma of bone | MicroRNA-490-3p regulates cell proliferation and apoptosis by targeting HMGA2 in... | BeFree | 26341146 | Detail |
| 0.008 | Carcinogenesis | These findings strongly suggest that MED12 mutations and HMGA2 overexpression ar... | BeFree | 24390224 | Detail |
| <0.001 | Tumor Initiation | NA | BeFree | Detail | |
| <0.001 | prostate carcinoma | NA | BeFree | Detail | |
| 0.001 | Epithelial ovarian cancer | Low miR-145 and high HMGA2 expressions are potential biomarkers of poor prognosi... | BeFree | 25444913 | Detail |
| 0.004 | Primary myelofibrosis | Abnormal expression of HMGA2 and CXCR4 in IM granulocytes was dependent on the p... | BeFree | 16990584 | Detail |
| 0.001 | breast carcinoma | NA | BeFree | Detail | |
| 0.001 | Carcinoma of lung | Finally, we demonstrate that the expression pattern of FHIT and miR-30c is inver... | BeFree | 25340791 | Detail |
| <0.001 | Benign bone neoplasm | NA | BeFree | Detail | |
| <0.001 | Secondary malignant neoplasm of lymph node | Further validation showed that overexpression of PSCA was significantly associat... | BeFree | 25502777 | Detail |
| <0.001 | colon carcinoma | NA | BeFree | Detail | |
| 0.002 | stomach carcinoma | Coexpression of HMGA2 and Oct4 predicts an unfavorable prognosis in human gastri... | BeFree | 25037576 | Detail |
| 0.002 | stomach carcinoma | RKIP inhibits gastric cancer cell survival and invasion by regulating the expres... | BeFree | 25172097 | Detail |
| <0.001 | Carcinoma of bladder | NA | BeFree | Detail | |
| <0.001 | Central neuroblastoma | NA | BeFree | Detail | |
| 0.003 | lymphangioleiomyomatosis | NA | BeFree,LHGDN | Detail | |
| <0.001 | malignant peripheral nerve sheath tumor | NA | BeFree | Detail | |
| <0.001 | Spots on skin | Beyond recalculating frequencies for the previously reported frequent integratio... | BeFree | 25581428 | Detail |
| <0.001 | Adenocarcinoma of lung, stage IV | NA | BeFree | Detail | |
| <0.001 | Growth failure | NA | BeFree | Detail | |
| 0.003 | ovarian neoplasm | NA | LHGDN | Detail | |
| 0.003 | chondroma | We here described clinical and pathological features in a new case of convexity ... | BeFree,LHGDN | 25250651 | Detail |
| <0.001 | Colon Lipoma | NA | BeFree | Detail | |
| <0.001 | Myolipoma | NA | BeFree | Detail | |
| 0.003 | Malignant neoplasm of ovary | Our findings suggest that miR-145 functions as a tumor suppressor in ovarian can... | BeFree | 25444913 | Detail |
| <0.001 | Squamous cell carcinoma of the head and neck | NA | BeFree | Detail | |
| <0.001 | Lipoblastoma | Lack of PLAG1 and HMGA2 expression in the majority of LLTV suggests that these l... | BeFree | 25929353 | Detail |
| 0.001 | sarcoma | NA | BeFree | Detail | |
| <0.001 | Myofibroma (morphologic abnormality) | NA | BeFree | Detail | |
| <0.001 | spindle cell rhabdomyosarcoma | NA | BeFree | Detail | |
| <0.001 | Atypical teratoid/rhabdoid tumor | Our results indicate a role for HMGA2 in AT/RT in vitro and in vivo and demonstr... | BeFree | 25575139 | Detail |
| <0.001 | soft tissue chondroma | Although the molecular mechanism underlying its pathogenesis remains largely unk... | BeFree | 25250651 | Detail |
| <0.001 | Chronic myeloproliferative disorder | Dysregulation of the MIRLET7/HMGA2 axis with methylation of the CDKN2A promoter ... | BeFree | 25236537 | Detail |
| <0.001 | Salivary duct carcinoma | NA | BeFree | Detail | |
| 0.002 | Aggressive angiomyxoma | NA | BeFree | Detail | |
| <0.001 | Ovarian Serous Adenocarcinoma | NA | BeFree | Detail | |
| <0.001 | pancreatic ductal adenocarcinoma | Importantly, we show that there is a statistically significant correlation betwe... | BeFree | 24807963 | Detail |
| <0.001 | Vaginal Leiomyoma | NA | BeFree | Detail | |
| <0.001 | Epithelioma | NA | BeFree | Detail | |
| 0.121 | Liposarcoma, well differentiated | NA | BeFree,ORPHANET | Detail | |
| 0.006 | Mammary Neoplasms | NA | BeFree,LHGDN | Detail | |
| <0.001 | Mammary Tumorigenesis | NA | BeFree | Detail | |
| <0.001 | Salivary Gland Pleomorphic Adenoma | NA | BeFree | Detail | |
| <0.001 | colorectal cancer | NA | BeFree | Detail | |
| <0.001 | Glioblastoma multiforme | NA | BeFree | Detail | |
| <0.001 | Non-Neoplastic Disorder | NA | BeFree | Detail | |
| 0.001 | Pygmy (disorder) | NA | BeFree | Detail | |
| <0.001 | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | Human HMGA2 protein overexpressed in mice induces precursor T-cell lymphoblastic... | BeFree | 25014774 | Detail |
| <0.001 | Precursor Cell Lymphoblastic Leukemia Lymphoma | NA | BeFree | Detail | |
| <0.001 | liver carcinoma | NA | BeFree | Detail | |
| <0.001 | Benign symmetrical lipomatosis | NA | BeFree | Detail | |
| <0.001 | Nasopharyngeal carcinoma | Downregulating HMGA2 attenuates epithelial-mesenchymal transition-induced invasi... | BeFree | 26025649 | Detail |
| 0.124 | Lipomatosis, Multiple | Further cytogenetic studies of pediatric lipoma would be useful to determinate w... | BeFree,CTD_human | 26319758 | Detail |
| <0.001 | Triple Negative Breast Neoplasms | NA | BeFree | Detail | |
| 0.003 | adenocarcinoma | NA | BeFree,LHGDN | Detail | |
| 0.002 | adenoma | NA | BeFree | Detail | |
| 0.004 | Primary myelofibrosis | A histone deacetylase inhibitor, panobinostat, significantly increased MIRLET7 e... | BeFree,LHGDN | 25236537 | Detail |
| <0.001 | beta thalassemia | NA | BeFree | Detail | |
| 0.120 | Birth Weight | NA | CTD_human | Detail | |
| <0.001 | Malignant neoplasm of urinary bladder | NA | BeFree | Detail | |
| <0.001 | Blast Phase | NA | BeFree | Detail | |
| 0.002 | Brain Diseases | NA | GAD | Detail | |
| 0.003 | Brain Neoplasms | High-mobility group A2 was recently identified as being upregulated in AT/RT tis... | BeFree,GAD | 25575139 | Detail |
| 0.001 | Malignant neoplasm of breast | NA | BeFree | Detail | |
| <0.001 | Malignant tumor of colon | NA | BeFree | Detail | |
| <0.001 | Malignant neoplasm of thyroid | Herein, we observed a strong correlation between the expression of HMGA2 and PLA... | BeFree | 24516594 | Detail |
| <0.001 | Non-small cell lung carcinoma | MUC1-C Induces the LIN28B→LET-7→HMGA2 Axis to Regulate Self-Renewal in NSCLC. | BeFree | 25368430 | Detail |
| <0.001 | Carcinoma, Papillary | NA | BeFree | Detail |
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| HMGA2 is down-regulated by microRNA let-7 and associated with epithelial-mesenchymal transition in o... | DisGeNET | Detail |
| The RT-PCR and immunohistochemistry analyses showed that HMGA2 was expressed in the great majority o... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Beyond recalculating frequencies for the previously reported frequent integration sites POU5F1B (9.7... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| These findings strongly suggest that MED12 mutations and HMGA2 overexpression are independent geneti... | DisGeNET | Detail |
| All leiomyomas with HMGA2 overexpression also revealed an activation of PLAG1 in the absence of dete... | DisGeNET | Detail |
| Whereas 70.0% (14/20) HMGA2-mutated fibroids made their appearance as solitary nodules, 85.5% (153/1... | DisGeNET | Detail |
| Overexpression of the truncated form of High Mobility Group A proteins (HMGA2) in human myometrial c... | DisGeNET | Detail |
| MED12 and HMGA2 mutations: two independent genetic events in uterine leiomyoma and leiomyosarcoma. | DisGeNET | Detail |
| These findings show that HMGA2-driven leukemia in mice closely resembles spontaneous human T-ALL, in... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Further cytogenetic studies of pediatric lipoma would be useful to determinate whether some partner ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Coexpression of HMGA2 and Oct4 predicts an unfavorable prognosis in human gastric cancer. | DisGeNET | Detail |
| RKIP inhibits gastric cancer cell survival and invasion by regulating the expression of HMGA2 and OP... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The RT-PCR and immunohistochemistry analyses showed that HMGA2 was expressed in the great majority o... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Overexpression of high mobility group AT-hook 2 (Hmga2), which is negatively regulated by MIRLET7 mi... | DisGeNET | Detail |
| Dysregulation of the MIRLET7/HMGA2 axis with methylation of the CDKN2A promoter in myeloproliferativ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The aim of this study was to analyze the association between HMGA2 and Oct4 expression and various c... | DisGeNET | Detail |
| Finally, we demonstrate that the expression pattern of FHIT and miR-30c is inversely correlated with... | DisGeNET | Detail |
| Here, we found that low miR-145 expression and HMGA2 overexpression determined by qRT-PCR and immuno... | DisGeNET | Detail |
| HMGA2 was upregulated in NPC cell lines and clinical specimens (P < 0.01), and HMGA2 expression corr... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| MicroRNA-490-3p regulates cell proliferation and apoptosis by targeting HMGA2 in osteosarcoma. | DisGeNET | Detail |
| Low miR-145 and high HMGA2 expressions are potential biomarkers of poor prognosis of ovarian carcino... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| HMGA2 mRNA expression, especially variant 1 with 3'UTR that contains MIRLET7-specific sites, rather ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| HMGA2 mRNA expression, especially variant 1 with 3'UTR that contains MIRLET7-specific sites, rather ... | DisGeNET | Detail |
| Correlated expression of HMGA2 and PLAG1 in thyroid tumors, uterine leiomyomas and experimental mode... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| MED12 and HMGA2 mutations: two independent genetic events in uterine leiomyoma and leiomyosarcoma. | DisGeNET | Detail |
| All leiomyomas with HMGA2 overexpression also revealed an activation of PLAG1 in the absence of dete... | DisGeNET | Detail |
| Whereas 70.0% (14/20) HMGA2-mutated fibroids made their appearance as solitary nodules, 85.5% (153/1... | DisGeNET | Detail |
| Overexpression of the truncated form of High Mobility Group A proteins (HMGA2) in human myometrial c... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The high mobility group A2 (HMGA2) protein was found to be highly expressed in human OSCC and its ex... | DisGeNET | Detail |
| Downregulating HMGA2 attenuates epithelial-mesenchymal transition-induced invasion and migration in ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| The high mobility group A2 (HMGA2) protein was found to be highly expressed in human OSCC and its ex... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Further validation showed that overexpression of PSCA was significantly associated with lymph node m... | DisGeNET | Detail |
| Downregulating HMGA2 attenuates epithelial-mesenchymal transition-induced invasion and migration in ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Finally, we demonstrate that the expression pattern of FHIT and miR-30c is inversely correlated with... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Further validation showed that overexpression of PSCA was significantly associated with lymph node m... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| MicroRNA-490-3p regulates cell proliferation and apoptosis by targeting HMGA2 in osteosarcoma. | DisGeNET | Detail |
| These findings strongly suggest that MED12 mutations and HMGA2 overexpression are independent geneti... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Low miR-145 and high HMGA2 expressions are potential biomarkers of poor prognosis of ovarian carcino... | DisGeNET | Detail |
| Abnormal expression of HMGA2 and CXCR4 in IM granulocytes was dependent on the presence and the muta... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Finally, we demonstrate that the expression pattern of FHIT and miR-30c is inversely correlated with... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Further validation showed that overexpression of PSCA was significantly associated with lymph node m... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Coexpression of HMGA2 and Oct4 predicts an unfavorable prognosis in human gastric cancer. | DisGeNET | Detail |
| RKIP inhibits gastric cancer cell survival and invasion by regulating the expression of HMGA2 and OP... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Beyond recalculating frequencies for the previously reported frequent integration sites POU5F1B (9.7... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| We here described clinical and pathological features in a new case of convexity dural chondroma with... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Our findings suggest that miR-145 functions as a tumor suppressor in ovarian cancer and directly tar... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Lack of PLAG1 and HMGA2 expression in the majority of LLTV suggests that these lesions are distinct ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Our results indicate a role for HMGA2 in AT/RT in vitro and in vivo and demonstrate that HMGA2 is a ... | DisGeNET | Detail |
| Although the molecular mechanism underlying its pathogenesis remains largely unknown, 12q13-15 rearr... | DisGeNET | Detail |
| Dysregulation of the MIRLET7/HMGA2 axis with methylation of the CDKN2A promoter in myeloproliferativ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Importantly, we show that there is a statistically significant correlation between BRD4 and HMGA2 in... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Human HMGA2 protein overexpressed in mice induces precursor T-cell lymphoblastic leukemia. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Downregulating HMGA2 attenuates epithelial-mesenchymal transition-induced invasion and migration in ... | DisGeNET | Detail |
| Further cytogenetic studies of pediatric lipoma would be useful to determinate whether some partner ... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| A histone deacetylase inhibitor, panobinostat, significantly increased MIRLET7 expression and reduce... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| High-mobility group A2 was recently identified as being upregulated in AT/RT tissue, but the role of... | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| NA | DisGeNET | Detail |
| Herein, we observed a strong correlation between the expression of HMGA2 and PLAG1 in 14 benign and ... | DisGeNET | Detail |
| MUC1-C Induces the LIN28B→LET-7→HMGA2 Axis to Regulate Self-Renewal in NSCLC. | DisGeNET | Detail |
| NA | DisGeNET | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- dbSNP
- rs386626619 dbSNP
- Genome
- hg19
- Position
- chr12:66,218,240-66,360,071
- Variant Type
- snv
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