Annotation Detail
Information
- Associated Genes
- HMGA2
- Associated Variants
-
HMGA2 MUTATION
HMGA2 MUTATION - Associated Disease
- myelofibrosis
- Source Database
- DisGeNET
- Description
- Overexpression of high mobility group AT-hook 2 (Hmga2), which is negatively regulated by MIRLET7 micro RNAs through 3'-untranslated region (3'UTR), causes proliferative haematopoiesis mimicking myeloproliferative neoplasms (MPNs) and contributes to progression of myelofibrosis in mice.
- Pubmed
- 25236537
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 1
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00108576748832121
Drugs