Annotation Detail
Information
- Associated Genes
- HMGA2
- Associated Variants
-
HMGA2 MUTATION
HMGA2 MUTATION - Associated Disease
- Primary myelofibrosis
- Source Database
- DisGeNET
- Description
- A histone deacetylase inhibitor, panobinostat, significantly increased MIRLET7 expression and reduced variant 1 of HMGA2 mRNA expression, but not variant 2, in both U937 cells and PMF-derived CD34(+) cells.
- Pubmed
- 25236537
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 5
- Original source reporting the Gene Disease association
- BeFree,LHGDN
- DisGENET score for the Gene Disease association
- 0.00408155960286869
Drugs